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Left subclavian artery coverage during thoracic endovascular aortic aneurysm repair does not mandate revascularization

Maldonado, Thomas S; Dexter, David; Rockman, Caron B; Veith, Frank J; Garg, Karan; Arko, Frank; Bertoni, Hernan; Ellozy, Sharif; Jordan, William; Woo, Edward
OBJECTIVE: This study assessed the risk of left subclavian artery (LSA) coverage and the role of revascularization in a large population of patients undergoing thoracic endovascular aortic aneurysm repair. METHODS: A retrospective multicenter review of 1189 patient records from 2000 to 2010 was performed. Major adverse events evaluated included cerebrovascular accident (CVA) and spinal cord ischemia (SCI). Subgroup analysis was performed for noncovered LSA (group A), covered LSA (group B), and covered/revascularized LSA (group C). RESULTS: Of 1189 patients, 394 had LSA coverage (33.1%), and 180 of these patients (46%) underwent LSA revascularization. In all patients, emergency operations (9.5% vs 4.3%; P = .001), renal failure (12.7% vs 5.3%; P = .001), hypertension (7% vs 2.3%; P = .01), and number of stents placed (1 = 3.7%, 2 = 7.4%, >/=3 = 10%; P = .005) were predictors of SCI. History of cerebrovascular disease (9.6% vs 3.5%; P = .002), chronic obstructive pulmonary disease (9.5% vs 5.4%; P = .01), coronary artery disease (8.5% vs 5.3%; P = .03), smoking (8.9% vs 4.2%) and female gender (5.3% men vs 8.2% women; P = .05) were predictors of CVA. Subgroup analysis showed no significant difference between groups B and C (SCI, 6.3% vs 6.1%; CVA, 6.7% vs 6.1%). LSA revascularization was not protective for SCI (7.5% vs 4.1%; P = .3) or CVA (6.1% vs 6.4%; P = .9). Women who underwent revascularization had an increased incidence of CVA event compared with all other subgroups (group A: 5.6% men, 8.4% women, P = .16; group B: 6.6% men, 5.3% women, P = .9; group C: 2.8% men, 11.9% women, P = .03). CONCLUSIONS: LSA coverage does not appear to result in an increased incidence of SCI or CVA event when a strategy of selective revascularization is adopted. Selective LSA revascularization results in similar outcomes among the three cohorts studied. Revascularization in women carries an increased risk of a CVA event and should be reserved for select cases.
PMID: 23021570
ISSN: 0741-5214
CID: 207302

Endovascular Grafts in the Treatment of Isolated Iliac Aneurysms

Chapter by: Berland, TL; Veith, Frank J; Garg, K; Cayne, NS
in: Haimovici's vascular surgery by Haimovici, Henry; Ascher, Enrico [Eds]
Chichester, West Sussex : Wiley-Blackwell, 2012
pp. 594-601
ISBN: 1444330713
CID: 845242

Further Consideration for Subclavian Revascularization with TEVAR

Garg, Karan; Maldonado, Thomas S
Management of the left subclavian artery (LSA) during thoracic endovascular aortic repair (TEVAR) continues to be controversial, despite recent guidelines submitted by the Society for Vascular Surgery recommending routine revascularization of the LSA in most circumstances. Up to one third of patients require coverage of the LSA during TEVAR. The LSA provides extensive circulation to the upper extremity, spinal cord, and brain, consequently, sacrifice of this great vessel might not be physiologically tolerated. Studies supporting routine preoperative revascularization of the LSA note increased rates of spinal cord ischemia, strokes, and upper extremity ischemia when the LSA is sacrificed. Other studies supporting a selective revascularization strategy note no difference in neurologic outcomes and recommend expectant management of upper extremity ischemia. In addition, LSA revascularization has associated complications that are avoided by selective revascularization. The purpose of this article is to review and focus the available data in support of routine versus selective LSA revascularization.
PMID: 23206571
ISSN: 0895-7967
CID: 197482

A Unique Technique for Intentional Occlusion of an Abdominal Aortic Aneurysm [Meeting Abstract]

Garg, Karan; Berland, Todd L.; Veith, Frank J.; Cayne, Neal S.
ISI:000308085500089
ISSN: 0741-5214
CID: 178298

Outcome of endovascular repair of popliteal artery aneurysm using the Viabahn endoprosthesis

Garg, Karan; Rockman, Caron B; Kim, Billy J; Jacobowitz, Glenn R; Maldonado, Thomas S; Adelman, Mark A; Veith, Frank J; Cayne, Neal S
OBJECTIVE: This study reviews a single-center experience of endovascular popliteal aneurysm (PAA) repair. METHODS: A retrospective review was performed to identify all endovascular PAA repairs performed between September 2004 and January 2011. RESULTS: We identified 21 patients (mean age, 74 +/- 9 years, 91% men) with PAAs (mean size, 2.89 +/- 1.0 cm) in 26 limbs, of which 38% were symptomatic. All patients underwent endovascular repair with a Viabahn covered stent graft (W. L. Gore & Assoc, Inc, Flagstaff, Ariz). Postoperatively, all patients were maintained on antiplatelet therapy with clopidogrel or aspirin, or both. Mean follow-up was 22 +/- 17 months (range, 1-57 months). One patient with one aneurysm was lost to follow-up. Primary and secondary patencies were both 91.2% at 1 year and were 85.5% and 91.2%, respectively, at 2 years. The limb salvage rate was 100%. Four stent graft failures occurred at a mean of 12.3 +/- 11 months. One technical failure due to stent graft infolding required conversion to an open femoral-popliteal bypass. Three additional graft failures occurred in patients with poor (single-vessel) runoff. Compared with patients with two- or three-vessel runoff, the graft failure rate in patients with single-vessel runoff was statistically significant (P = .02). Two of the graft failures were successfully treated with open thrombectomy, and one required a tibial artery bypass for limb salvage. CONCLUSIONS: Endovascular repair of PAAs is feasible and has acceptable midterm patency rates. Poor distal runoff predicted graft failure.
PMID: 22608040
ISSN: 0741-5214
CID: 167506

Contemporary presentation and management of carotid artery aneurysms and pseudoaneurysms

Garg, K; Rockman, CB; Lee, V; Maldonado, TS; Jacobowitz, GR; Adelman, MA; Mussa, FF
OBJECTIVE: The objective of this study was to review a single-institution contemporary experience with extracranial aneurysms of the carotid artery. METHODS: A retrospective review was conducted of patients evaluated for an aneurysm of the extracranial carotid artery from 2005 to 2010. Demographics, presentation, and operative management were reviewed. The mean follow-up was 22 months (range, 1-58 months). RESULTS: Over the study period, 16 aneurysms and pseudoaneurysms were identified in 15 patients. Of these, 14 aneurysms (in six men and eight women with mean age of 63 years) underwent surgical repair. The mean aneurysm size was 2.45 cm (range, 0.8-5 cm). One aneurysm (7.1%) was associated with neurologic symptoms, and 13 were asymptomatic. The underlying etiology was trauma in five (35.7%), prior carotid endarterectomy in five (35.7%), and degenerative atherosclerosis in four (28.6%). Aneurysms were isolated to the common carotid artery in six (42.9%), internal carotid artery in five (35.7%), and carotid bifurcation in three (21.4%). Five patients underwent aneurysmectomy with primary repair; seven underwent repair with an interposition graft, one required an innominate to common carotid artery bypass, and one patient had a plication and patch angioplasty. No mortalities or neurologic events were documented within 30 days. One patient had transient cranial nerve palsy. One patient required reintervention at 4 months for stenosis of the bypass graft, and one patient died at 10 months from an unrelated condition. There were no neurologic events on follow-up. CONCLUSIONS: Carotid artery aneurysms and pseudoaneurysms are uncommon and usually asymptomatic. Prior trauma and carotid surgery were common etiologies. The location of the aneurysms was equally distributed between the internal and common carotid arteries. Surgical repair was safe and effective with no significant morbidity or mortality and good midterm stroke prevention.
PMID: 22341576
ISSN: 0741-5214
CID: 162331

Midterm Outcome of Endovascular Popliteal Artery Aneurysm Repair Using the Viabahn Endoprosthesis [Meeting Abstract]

Garg, Karan; Rockman, Caron B; Kim, Billy J; Jacobowitz, Glenn R; Maldonado, Thomas S; Lamparello, Patrick J; Adelman, Mark A; Veith, Frank J; Cayne, Neal S
ISI:000294505300055
ISSN: 0741-5214
CID: 2726002

Contemporary Presentation and Management of Carotid Artery Aneurysms [Meeting Abstract]

Garg, Karan; Lee, Victoria; Rockman, Caron B; Maldonado, Thomas S; Jacobowitz, Glenn R; Cayne, Neal S; Adelman, Mark A; Mussa, Firas F
ISI:000294505300065
ISSN: 0741-5214
CID: 2726012

Surgical relief of small bowel obstruction by migrated biliary stent: extraction without enterotomy

Garg, Karan; Zagzag, Jonathan; Khaykis, Inessa; Liang, Howard
BACKGROUND: Distal stent migration is a well-known complication following insertion of biliary stents. Most such cases can be managed expectantly, because the stents pass through the gastrointestinal tract. However, small bowel obstruction as a result of the stent mandates surgical intervention. METHODS: We report the case of a patient who had distal stent migration causing a small bowel obstruction. We successfully retrieved the stent without an enterotomy, by using a combination of laparoscopy, endoscopy, and fluoroscopy. Our unique technique greatly decreased the risk of bacterial peritonitis in this patient with decompensated cirrhosis and associated ascites, which in this patient population results in a high mortality. RESULTS: Management of small bowel obstruction secondary to biliary stent migration necessitates operative intervention. Retrieval of a dislodged stent can be performed safely without subjecting the patient to an enterotomy or a small bowel resection. Postoperative morbidity should be significantly reduced by this approach. CONCLUSION: Retrieval of biliary stents in cases of small bowel obstruction without perforation may be successfully performed without enterotomy or bowel resection. A similar approach may be applied to other foreign bodies dislodged in the small bowel
PMCID:3148878
PMID: 21902982
ISSN: 1086-8089
CID: 139040

Cystic adventitial disease of the popliteal artery: is there a consensus in management?

Baxter, Andrew R; Garg, Karan; Lamparello, Patrick J; Mussa, Firas F; Cayne, Neal S; Berland, Todd
Cystic adventitial disease (CAD) is a well described disease entity that commonly affects the popliteal artery, presenting as a rare cause of non-atherosclerotic claudication. The traditional surgical approaches are cyst resection and bypass, or cyst evacuation or aspiration. We report the case of a 58-year-old female with CAD of the popliteal artery treated successfully with cyst resection and bypass using an autologous graft. We reviewed the literature over the last 25 years on management and outcomes of CAD of the popliteal artery. We identified a total of 123 cases; most cases were treated using a traditional repair, while 3 cases used an endovascular approach. The overall success rate using bypass was 93.3%, compared to 85% in the evacuation/aspiration cohort. All cases treated endovascularly resulted in failure. While no consensus exists regarding the preferred modality to treat CAD, we believe that resection of the cyst and bypass affords the best outcomes
PMID: 21652669
ISSN: 1708-5381
CID: 134316