Faculty Bibliography
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235
HOSPITAL READMISSION FOLLOWING PERIOPERATIVE ACUTE MYOCARDIAL INFARCTION ASSOCIATED WITH NON-CARDIAC SURGERY [Meeting Abstract]
ISI:000429659705123
ISSN: 0735-1097
CID: 3055212
ASSOCIATIONS BETWEEN CONVENTIONAL CARDIOVASCULAR RISK FACTORS AND RISK OF PERIOPERATIVE ACUTE MYOCARDIAL INFARCTION AFTER NON-CARDIAC SURGERY [Meeting Abstract]
ISI:000429659703516
ISSN: 0735-1097
CID: 3055252
THE IMPACT OF CARDIOVASCULAR DISEASE RISK FACTORS ON ATHEROSCLEROSIS IN PSORIASIS [Meeting Abstract]
ISI:000429659703510
ISSN: 0735-1097
CID: 3055262
LEFT VENTRICULAR WALL MOTION FINDINGS IN MYOCARDIAL INFARCTION WITH NONOBSTRUCTIVE CORONARY ARTERY DISEASE (MINOCA) [Meeting Abstract]
ISI:000429659700136
ISSN: 0735-1097
CID: 3055342
ACUTE MYOCARDIAL INFARCTION DURING PREGNANCY AND THE PUERPERIUM IN THE UNITED STATES [Meeting Abstract]
ISI:000429659700006
ISSN: 0735-1097
CID: 3055362
Hospital Readmission After Perioperative Acute Myocardial Infarction Associated With Noncardiac Surgery
PMCID:5995321
PMID: 29525764
ISSN: 1524-4539
CID: 2994102
Letter by Smilowitz Regarding Article, "Three-Vessel Assessment of Coronary Microvascular Dysfunction in Patients With Clinical Suspicion of Ischemia: Prospective Observational Study With the Index of Microcirculatory Resistance" [Letter]
PMCID:5798473
PMID: 29386189
ISSN: 1941-7632
CID: 2933402
Trends in cardiovascular risk factor and disease prevalence in patients undergoing non-cardiac surgery
OBJECTIVES/OBJECTIVE:Cardiovascular risk factors are prevalent in the population undergoing non-cardiac surgery. Changes in perioperative cardiovascular risk factor profiles over time are unknown. The objective of this study was to evaluate national trends in cardiovascular risk factors and atherosclerotic cardiovascular disease (ASCVD) among patients undergoing non-cardiac surgery. METHODS:Adults aged ≥45 years old who underwent non-cardiac surgery were identified using the US National Inpatient Sample from 2004 to 2013. The prevalence of traditional cardiovascular risk factors (hypertension, dyslipidaemia, diabetes mellitus, obesity and chronic kidney disease) and ASCVD (coronary artery disease, peripheral artery disease and prior stroke] were evaluated over time. RESULTS:A total of 10 581 621 hospitalisations for major non-cardiac surgery were identified. Between 2008 and 2013, ≥2 cardiovascular risk factors and ASCVD were present in 44.5% and 24.3% of cases, respectively. Over time, the prevalence of multiple (≥2) cardiovascular risk factors increased from 40.5% in 2008-2009 to 48.2% in 2012-2013, P<0.001. The proportion of patients with coronary artery disease (17.2% in 2004-2005 vs 18.2% in 2012-2013, P<0.001), peripheral artery disease (6.3% in 2004-2005 vs 7.4% in 2012-2013, P<0.001) and prior stroke (3.5% in 2008-2009 vs 4.7% 2012-2013, P<0.001) also increased over time. The proportion of patients with a modified Revised Cardiac Risk Index score ≥3 increased from 6.6% in 2008-2009 to 7.7% in 2012-2013 (P<0.001). CONCLUSIONS:Among patients undergoing major non-cardiac surgery, the burden of cardiovascular risk factors and the prevalence of ASCVD increased over time. Adverse trends in risk profiles require continued attention to improve perioperative cardiovascular outcomes.
PMCID:6102124
PMID: 29305561
ISSN: 1468-201x
CID: 2899442
Controversies Surrounding Authorship of Manuscripts by Industry Employees: Academic and Industry Perspectives
AIMS/OBJECTIVE:The medical device and pharmaceutical industries play an essential role in the development of cardiovascular devices and drugs, and industry employees are frequently listed as co-authors of clinical trials published in peer-reviewed journals. Potential conflicts of interest in biomedical research have attracted significant attention in recent years, but issues and challenges surrounding authors who are industry employees have not received nearly as much scrutiny. METHODS AND RESULTS/RESULTS:We present a comprehensive discussion of the concerns and challenges regarding the role of industry in the authorship of scientific manuscripts. Academic co-authors, industry employees, the editors of medical journals, and, most importantly, readers, need to consider the perception and implications that accompany industry employee authorship. Potential concerns include the effect of industry authors (and industry support) on study design, data analysis, interpretations, conclusions, and, ultimately, scientific content. CONCLUSIONS:Meaningful contributions from industry employees must be acknowledged and reported in scientific and clinical publications. Efforts to provide full transparency on industry support and the role of industry contributors are necessary to maintain confidence in the reports of studies with industry involvement.
PMID: 29278351
ISSN: 1969-6213
CID: 2895952
Systemic lupus erythematosus and the risk of perioperative major adverse cardiovascular events
Systemic lupus erythematosus (SLE) is a significant risk factor for cardiovascular disease. The relationship between SLE and perioperative cardiovascular risks following non-cardiac surgery is uncertain. We investigated associations between a diagnosis of SLE and outcomes following major non-cardiac surgery in a large national database from the United States. Patients age ≥ 18 years requiring major non-cardiac surgery were identified from Healthcare Cost and Utilization Project's National Inpatient Sample data from 2004 to 2014. Systemic lupus erythematosus and perioperative major adverse cardiovascular events (MACE; myocardial infarction, ischemic stroke or death) were defined by ICD-9 diagnosis codes. Perioperative MACE were reported for SLE patients stratified by age and sex. From 2004 to 2014, a total of 17,853,194 hospitalizations for major non-cardiac surgery met study inclusion criteria. SLE was identified in 70,578 (0.4%) hospitalizations. Overall, the frequency of perioperative MACE was higher in patients with vs. without SLE [2.4 vs. 2.0%, p < 0.001; adjusted OR (aOR) 1.25; 95% CI 1.18-1.31]. Perioperative MACE associated with SLE was largely driven by increased death (aOR 1.58 95% CI 1.40-1.77) and myocardial infarction (aOR 1.32; 95% CI 1.05-1.66) in younger patients with SLE. The increased risk of perioperative MACE associated with SLE in younger patients was attenuated with increasing age. A diagnosis of SLE is associated with increased risk of perioperative MACE, particularly among younger patients. Efforts to improve the perioperative management and outcomes of patients with SLE are needed.
PMCID:5756514
PMID: 29230625
ISSN: 1573-742x
CID: 2844452
