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Clinical and radiographic comparison of a hybrid cage glenoid to a cemented polyethylene glenoid in anatomic total shoulder arthroplasty
Friedman, Richard J; Cheung, Emilie; Grey, Sean G; Flurin, Pierre-Henri; Wright, Thomas W; Zuckerman, Joseph D; Roche, Christopher P
BACKGROUND:This study reports the clinical and radiographic outcomes of a hybrid cage glenoid compared with an age-matched, sex-matched, and follow-up-matched cohort of cemented all-polyethylene peg glenoids in patients undergoing anatomic total shoulder arthroplasty with 2 years' minimum follow-up. MATERIALS AND METHODS/METHODS:We reviewed 632 primary anatomic total shoulder arthroplasty patients from an international multi-institutional database; 316 patients received hybrid cage glenoids and were matched for age, sex, and follow-up with 316 patients with cemented all-polyethylene peg glenoids. Each cohort received the same humeral component. Scoring was performed in all patients preoperatively and at latest follow-up using 5 outcome scoring metrics and 4 active range-of-motion measurements. A Student 2-tailed unpaired t test identified differences in outcomes; P < .05 denoted a significant difference. RESULTS:Cage glenoid patients had significantly lower rates of radiolucent glenoid lines (9.0% vs. 37.6%, P < .0001) and radiolucent humeral lines (3.0% vs. 9.1%, P = .0088) than all-polyethylene peg glenoid patients. In the cage glenoid cohort, 4 cases of aseptic glenoid loosening (1.3%) and 4 cases of articular surface dissociation (1.3%) occurred. In the all-polyethylene peg cohort, 12 cases of aseptic loosening (3.8%) occurred. Cage glenoid patients had a significantly lower revision rate than all-polyethylene peg glenoid patients (2.5% vs. 6.9%, P = .0088). CONCLUSION/CONCLUSIONS:At 50 months' mean follow-up, cage glenoids demonstrated equally good clinical outcomes to all-polyethylene peg glenoids. Cage glenoids had significantly fewer radiolucent lines around both the glenoid and humeral components and a lower revision rate. Longer-term follow-up is required to confirm these promising short-term results.
PMID: 31324502
ISSN: 1532-6500
CID: 3978172
Microbial colonization of subscapularis tagging sutures in shoulder arthroplasty: a prospective, controlled study
Roach, Ryan; Yu, Stephen; Pham, Hien; Pham, Vinh; Virk, Mandeep; Zuckerman, Joseph D
BACKGROUND:Reducing intraoperative wound contamination is a critical preventive strategy for reducing the risk of prosthetic joint infection in shoulder arthroplasty. The aim of this study was to investigate the potential microbial colonization of subscapularis tagging sutures during shoulder arthroplasty. METHODS:In this prospective study, 50 consecutive patients undergoing primary shoulder arthroplasty (anatomic or reverse) were enrolled. Patients with revision shoulder arthroplasty and proximal humeral fractures were excluded. Nonabsorbable, braided tagging sutures were placed through the subscapularis tendon prior to tenotomy. A similar nonabsorbable, braided suture (control) was placed in a sterile container on the back table, open to the operating room environment. Subscapularis tagging sutures (experimental specimens) and control sutures were collected prior to subscapularis tenotomy repair and submitted for aerobic and anaerobic cultures. Cultures were held for 21 days to account for extended growth of slow-growing bacteria. RESULTS:A total of 12 of 50 experimental and 16 of 50 control sutures had positive cultures. Staphylococcus epidermidis and Cutibacterium acnes were the 2 most commonly isolated organisms. Active tobacco use (P = .038) and procedure length (P = .03) were significantly associated with positive cultures. No significant association between positive subscapularis tagging suture cultures and positive control cultures was found (P = .551). Patient age, sex, body mass index, and significant medical comorbidities were not significantly associated with positive cultures. DISCUSSION/CONCLUSIONS:Subscapularis tagging sutures are a potential source of microbial contaminant in shoulder arthroplasty, and we recommend exchanging the tagging suture with a suture opened immediately prior to subscapularis repair.
PMID: 31300367
ISSN: 1532-6500
CID: 3976942
Policy and Ethical Considerations for Widespread Utilization of Generic Orthopedic Implants
Pean, Christian A; Lajam, Claudette; Zuckerman, Joseph; Bosco, Joseph
PMCID:6588801
PMID: 31286053
ISSN: 2352-3441
CID: 3973852
2019 Frank Stinchfield Award: A comparison of prosthetic joint infection rates between direct anterior and non-anterior approach total hip arthroplasty
Aggarwal, V K; Weintraub, S; Klock, J; Stachel, A; Phillips, M; Schwarzkopf, R; Iorio, R; Bosco, J; Zuckerman, J D; Vigdorchik, J M; Long, W J
AIMS/OBJECTIVE:non-anterior (NA) surgical approaches on prosthetic joint infection (PJI), and examined the impact of new perioperative protocols on PJI rates following all surgical approaches at a single institution. PATIENTS AND METHODS/METHODS:(13.3 to 57.6, sd 6.1), respectively. Infection rates were calculated yearly for the DA and NA approach groups. Covariates were assessed and used in multivariate analysis to calculate adjusted odds ratios (ORs) for risk of development of PJI with DA compared with NA approaches. In order to determine the effect of adopting a set of infection prevention protocols on PJI, we calculated ORs for PJI comparing patients undergoing THA for two distinct time periods: 2013 to 2014 and 2015 to 2016. These periods corresponded to before and after we implemented a set of perioperative infection protocols. RESULTS:There were 1985 patients in the DA group and 4101 patients in the NA group. The overall rate of PJI at our institution during the study period was 0.82% (50/6086) and decreased from 0.96% (12/1245) in 2013 to 0.53% (10/1870) in 2016. There were 24 deep PJIs in the DA group (1.22%) and 26 deep PJIs in the NA group (0.63%; p = 0.023). After multivariate analysis, the DA approach was 2.2 times more likely to result in PJI than the NA approach (OR 2.2 (95% confidence interval 1.1 to 3.9); p = 0.006) for the overall study period. CONCLUSION/CONCLUSIONS:2019;101-B(6 Supple B):2-8.
PMID: 31146560
ISSN: 2049-4408
CID: 3929622
Posterior augmented glenoids compared to non-augmented glenoids in anatomic total shoulder arthroplasty [Meeting Abstract]
Friedman, R J; Grey, S; Wright, T W; Flurin, P -H; Zuckerman, J D; Roche, C
Purpose: The use of a posterior augmented glenoid to correct posterior wear, subluxation and retroversion remains controversial. The purpose of this study is to compare the clinical and radiographic outcomes of patients with significant posterior glenoid wear treated with a posterior augmented glenoid and compare them to age/gender/follow-up matched patients without glenoid wear treated with a non-augmented pegged glenoid in anatomic total shoulder arthroplasty (aTSA). Method(s): 182 patients undergoing primary aTSA with 2 year minimum follow-up (mean 42 months)were reviewed. 91 patients (mean age = 66 yrs; 37F/54M)received a posterior augmented pegged glenoid and 91 age/gender/follow-up matched patients received a non-augmented pegged glenoid. Patient data was retrospectively reviewed from a multi-institutional WIRB approved registry. Each patient was evaluated preoperatively and at latest follow-up using SST, UCLA, ASES, Constant, and SPADI scoring metrics; active abduction, forward flexion, and internal/external rotation were measured. Radiolucent glenoid line assessment was performed from radiographs at latest follow up. A Student's two tailed unpaired t-test (P <.05)quantified differences. Result(s): Each cohort demonstrated significant improvements in pain and function following primary aTSA. At latest follow-up, augmented glenoids were generally better than non-augmented glenoids; however, few differences were noted in pre-to-postoperative improvement between augmented and non-augmented glenoids. Augmented glenoids were associated with significantly more improvement in active abduction, forward flexion, and external rotation as compared to non-augmented glenoids. The overall complication rate was 6.6%, where augmented patients had 1 aseptic glenoid loosening compared to 3 cases in the non-augmented group. Radiographic data was available for 70% of the patients. There were no significant differences in the rate of glenoid radiolucent lines (35% augmented, 40% non-augmented)or the average line grade (0.68 augmented, 0.86 non-augmented)between the two cohorts. There were no differences in humeral radiolucent line rates between the two groups. Discussion(s): At a mean follow-up of 3.5 years, few clinically relevant differences were observed between the augmented and non-augmented cohorts, despite the augment cohort being disadvantaged by posterior glenoid wear. This is likely due to the correction of the retroversion and posterior subluxation, with improved tensioning of the rotator cuff. There were no patients in which the humeral head re-subluxated posteriorly. Complication rates and radiographic outcomes were similar between the two groups. Posterior augmented glenoids are a viable option for the posteriorly worn osteoarthritic glenoid; however, longer follow-up is necessary to determine how these early results hold up over time.
EMBASE:2001991230
ISSN: 1058-2746
CID: 3904752
Subscapularis-Sparing Total Shoulder Arthroplasty: A Prospective, Double-Blinded, Randomized Clinical Trial
Kwon, Young W; Zuckerman, Joseph D
Although total shoulder arthroplasty (TSA) is generally associated with good to excellent outcomes in most patients, the integrity and function of the subscapularis tendon (SSC) is of paramount importance because SSC rupture after TSA can lead to inferior outcomes. Therefore, the efficacy of a SSC-sparing TSA procedure was evaluated through a prospective, double-blinded, randomized study. Patients with end-stage osteoarthritis of the shoulder were randomized into 2 groups. Group 1 patients were treated with TSA in which the prosthesis was inserted entirely through the rotator interval without violating the SSC tendon (SPARING). Group 2 patients were treated with TSA using the SSC tenotomy approach (STANDARD). Both the patients and the evaluators remained blinded to the surgical approach throughout the study. Outcome data collected included the visual analog scale score for pain and the American Shoulder and Elbow Surgeons outcome score. Complete 2-year outcome data were collected from 32 SPARING and 38 STANDARD patients at a mean follow-up of 31.1 and 33.4 months, respectively. The American Shoulder and Elbow Surgeons and visual analog scale scores improved significantly for both groups. Differences between groups did not reach statistical significance. Complication profiles were similar for the 2 groups, with 3 patients in the SPARING group and 2 patients in the STANDARD group requiring revision surgery during the study. At short-term follow-up, the outcome of TSA using the SSC-sparing surgical approach was similar to the outcome of TSA using the standard approach. Studies with longer follow-up are required to document the potential benefits of this surgical technique. [Orthopedics. 2019; 42(1):e61-e67.].
PMID: 30427055
ISSN: 1938-2367
CID: 3631152
Effect of Tuberosity Healing on Clinical Outcomes in Elderly Patients Treated With a Reverse Shoulder Arthroplasty for 3- and 4-Part Proximal Humerus Fractures
Simovitch, Ryan W; Roche, Chris P; Jones, Richard B; Routman, Howard D; Marczuk, Yann; Wright, Thomas W; Zuckerman, Joseph D
OBJECTIVES/OBJECTIVE:To evaluate tuberosity union rate and clinical outcome after 3- and 4-part proximal humerus fractures in the elderly. DESIGN/METHODS:Retrospective, multicenter database cohort study. SETTING/METHODS:Level I and Level II trauma centers. PATIENTS/METHODS:Fifty-five patients older than 65 years had insertion of reverse shoulder arthroplasty (RTSA) for OTA/AO 11-B and 11-C proximal humerus fractures. INTERVENTION/METHODS:Treatment with RTSA using a dedicated low profile onlay fracture stem using variable tuberosity fixation. MAIN OUTCOME MEASURES/METHODS:Constant score, the American Shoulder and Elbow Surgeons score, Shoulder Pain and Disability Index score, University of California at Los Angeles score, Simple Shoulder Test score, visual analog pain score, shoulder function score, active range of motion, external rotation (ER)-specific tasks and position, rate of greater tuberosity healing, effect of tuberosity healing on overall clinical metrics, incidence of humeral lucency, and scapular notching. RESULTS:Eighty-three percent of the greater tuberosities that were repaired united. Greater tuberosity union resulted in greater active ER (P = 0.0415). There was a statistically significant difference in the ability to do ER-type activities between the 2 cohorts reflected in the ability to position one's hand behind their head with the elbow forward (P = 0.002) and comb their hair (P < 0.001). CONCLUSION/CONCLUSIONS:The use of a low profile onlay fracture stem in RTSA for acute 3- and 4-part proximal humerus fractures in the elderly can result in a high tuberosity union rate. Greater tuberosity healing significantly influences ER and ER-type activities that are not apparent by analysis of the overall metrics studied. LEVEL OF EVIDENCE/METHODS:Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
PMID: 30688837
ISSN: 1531-2291
CID: 3626362
Preoperative bisphosphonate treatment may adversely affect the outcome after shoulder arthroplasty
Mai, D H; Oh, C; Doany, M E; Rokito, A S; Kwon, Y W; Zuckerman, J D; Virk, M S
AIMS/OBJECTIVE:The aim of this study was to investigate the effects of preoperative bisphosphonate treatment on the intra- and postoperative outcomes of arthroplasty of the shoulder. The hypothesis was that previous bisphosphonate treatment would adversely affect both intra- and postoperative outcomes. PATIENTS AND METHODS/METHODS:group, there were 52 female and six male patients, with a mean age of 72.1 years (53 to 88). RESULTS:Previous treatment with bisphosphonates was positively associated with intraoperative complications (fracture; odds ratio (OR) 39.40, 95% confidence interval (CI) 2.42 to 6305.70) and one-year postoperative complications (OR 7.83, 95% CI 1.11 to 128.82), but did not achieve statistical significance for complications two years postoperatively (OR 3.45, 95% CI 0.65 to 25.28). The power was 63% for complications at one year. CONCLUSION/CONCLUSIONS:Patients who are treated with bisphosphonates during the three-year period before shoulder arthroplasty have a greater risk of intraoperative and one-year postoperative complications compared with those without this previous treatment.
PMID: 30700113
ISSN: 2049-4408
CID: 3626202
Results of total shoulder arthroplasty in patients aged 55 years or younger versus those older than 55 years: an analysis of 1135 patients with over 2 years of follow-up
Patel, Ravi B; Muh, Stephanie; Okoroha, Kelechi R; Wright, Thomas W; Flurin, Pierre-Henri; Roche, Christopher; Zuckerman, Joseph D
BACKGROUND:The results of anatomic total shoulder arthroplasty (TSA) in younger patients have not been clearly elucidated. The purpose of this study was to compare early outcomes after TSA in patients aged 55 years or younger versus patients older than 55 years. METHODS:A total of 1135 patients who were treated with TSA for glenohumeral arthritis and had a mean follow-up period of over 4 years were retrospectively reviewed. Etiologies included osteoarthritis (n = 1044), osteonecrosis (n = 35), inflammatory arthritis (n = 34), and post-traumatic arthritis (n = 22). Validated outcome measures, range of motion, and patient satisfaction were recorded. Preoperative and postoperative metrics were compared, and a multivariate analysis was performed to isolate age from sex, body mass index, previous surgery, and diagnosis as independent factors. RESULTS:Female patients, patients with a history of surgery, and patients with a diagnosis of osteonecrosis were more likely to undergo TSA when aged 55 years or younger. Both age groups showed similar preoperative range of motion and showed no differences in recorded outcome scores. Postoperatively, patients older than 55 years had slightly greater active abduction (P = .004) and internal rotation (P = .030). A higher percentage of patients older than 55 years rated their outcome as better or much better compared with those aged 55 years or younger (P = .003). CONCLUSIONS:Female sex, a history of surgery, and a diagnosis of osteonecrosis were associated with undergoing TSA when aged 55 years or younger. Despite similar preoperative function and minor differences in postoperative range of motion and outcome scores, patients aged 55 years or younger reported lower overall satisfaction with their TSA.
PMID: 30591214
ISSN: 1532-6500
CID: 3560482
Multilevel glenoid morphology and retroversion assessment in Walch B2 and B3 types
Samim, Mohammad; Virk, Mandeep; Mai, David; Munawar, Kamran; Zuckerman, Joseph; Gyftopoulos, Soterios
OBJECTIVE:A major factor that impacts the long-term outcome and complication rates of total shoulder arthroplasty is the preoperative posterior glenoid bone loss quantified by glenoid retroversion. The purpose of this study was to assess if glenoid retroversion varies significantly at different glenoid heights in Walch B2 and B3 glenoids. MATERIALS AND METHODS/METHODS:Patients with B2 and B3 glenoid types were included following retrospective review of 386 consecutive CT shoulder studies performed for arthroplasty preoperative planning. True axial CT reconstructions were created using a validated technique. Two readers independently measured the glenoid retroversion angles according to the Friedman method using the "intermediate" glenoid at three glenoid heights: 75% (upper), 50% (equator), and 25% (lower). The variances between the three levels for a given patient were calculated. RESULTS:Twenty-nine B2 and 8 B3 glenoid types were included. There was no significant difference in variance of glenoid version among the three levels in B2 or B3 groups. The mean variance in retroversion degree between equator-lower, upper-equator, and upper-lower glenoid was - 0.4, 0.3, and - 0.2 for B2; and - 0.2, 1.9, and 1.9 for B3 glenoid, respectively. The level of inter-reader agreement was fair to good for variance at equator-lower, and good to excellent for upper-equator and upper-lower glenoid. CONCLUSIONS:Glenoid version can be accurately measured at any level between 25 and 75% of glenoid height for Walch B2 and B3. We recommend that the glenoid equator be used as the reference to assure consistent and reliable version measurements in this group of patients.
PMID: 30328484
ISSN: 1432-2161
CID: 3368512