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Hybrid cage glenoids compared to cemented peg glenoids in anatomic total shoulder arthroplasty [Meeting Abstract]

Friedman, R J; Flurin, P -H; Grey, S G; Wright, T W; Zuckerman, J D; Roche, C
Introduction: Aseptic glenoid loosening remains a long-term complication of total shoulder arthroplasty (TSA). To improve long-term fixation and decrease the risk of aseptic loosening, glenoid components with hybrid fixation, consisting of a large metal ingrowth central peg and cemented peripheral pegs, have been developed. The purpose of this prospective study is to determine the clinical and radiographic outcomes of a hybrid cage glenoid component compared to an age and gender matched polyethylene (PE) peg glenoid component with a minimum tow year follow-up. Methods: Three hundred and seventy-two patients with a mean age of 65 years were treated with a TSA for osteoarthritis by 7 sur-geons using either a cemented pegged glenoid or a hybrid fixation cage glenoid. 186 patients who received a cage glenoid (94 female and 92 males) were matched for sex and age with 186 patients who received a peg glenoid. The patients were scored preoperatively and at latest follow-up using the SST, UCLA, ASES, Constant, and SPADI metrics; active abduction, forward flexion, and active and passive external rotation were also measured. The average follow-up for all patients was 32 months (cage 31 months; peg 33 months). A St-udent's two-tailed, unpaired t-test was used to identify differences in preoperative, postoperative, and pre-to-post-operative improve-ments in results, where P <.05 denoted a significant difference. IRB approval was obtained at each institution. Results: All patients demonstrated significant improvements in pain and function following TSA with a cage or peg glenoid (P <.0001). For the cage prosthesis, ASES scores improved from 38 to 89, Constant scores from 40 to 76 (P <.0001). Significant improvements were also seen in the SST, UCLA and SPADI scores (P <.001). For the peg glenoid, ASES scores improved from 34 to 81, Constant scores from 36 to 69 (P <.0001), and significant improvements were also seen in the SST, UCLA and SPADI scores (P <.0001). Active forward flexion for a cage glenoid improved from 103degree to 151degree and active external rotation from 24degree to 54degree. Active forward flexion for a peg prosthesis improved from 93degree to 141degree and active external rotation from 18degree to 49degree (all P <.0001). Cemented peg glenoids were noted to have significantly lower preoperative ab-duction, active forward flexion and external rotation measurements (but not clinically meaningful differences) and there were significant differences in the preoperative scoring metrics between the two groups. Postoperatively, the cage prosthesis was significantly higher for all 5 scoring metrics, and significantly better in active forward flexion and external rotation, though unlikely clinically significant. Cage patients had significantly less blood loss than peg patients (mean 224 cc vs 268 cc; P =.0006). Radiographic data was available for 65% of cases. Radiolucent lines (RLL) were noted in 10% of cage glenoid patients and 28% of peg patients (P =.0003). The average RLL score was also significantly less in the cage group compared to the peg patients (.24 vs.51, P =.02). There were 2 revisions in the cage group and 6 in the peg group. The complication rate was 3.2% in the cage glenoid cohort and 8.6% in the peg cohort (P =.028). Discussion: Similar or better clinical outcomes were found at a minimum two years follow-up comparing a hybrid cage glenoid prosthesis with a cemented peg glenoid. Short-term results demon-strate statistically significant clinical improvements in both groups. Radiographically, there was a highly significant decrease in the incidence of RLL and average RLL grade following implantation of a cage glenoid relative to cemented peg glenoid, with an almost 3 times reduction in the appearance of RLL. Less blood loss was seen due to the decreased operative time. Despite widespread use of hybrid glenoids, there is little clinical data demonstrating any differences. This is the largest series to date and the first to demonstrate a decrease in the incidence of radiolucent lines following implantation of a hybrid cage glenoid component. Additional and longer-term follow-up is needed to confirm these early outcomes
EMBASE:622879259
ISSN: 1532-6500
CID: 3193642

A Comparison of Assessment Tools: Is Direct Observation an Improvement Over Objective Structured Clinical Examinations for Communications Skills Evaluation?

Goch, Abraham M; Karia, Raj; Taormina, David; Kalet, Adina; Zuckerman, Joseph; Egol, Kenneth A; Phillips, Donna
Background /UNASSIGNED:Evaluation of resident physicians' communications skills is a challenging task and is increasingly accomplished with standardized examinations. There exists a need to identify the effective, efficient methods for assessment of communications skills. Objective /UNASSIGNED:We compared objective structured clinical examination (OSCE) and direct observation as approaches for assessing resident communications skills. Methods /UNASSIGNED:We conducted a retrospective cohort analysis of orthopaedic surgery resident physicians at a single tertiary care academic institution, using the Institute for Healthcare Communication "4 Es" model for effective communication. Data were collected between 2011 and 2015. A total of 28 residents, each with OSCE and complete direct observation assessment checklists, were included in the analysis. Residents were included if they had 1 OSCE assessment and 2 or more complete direct observation assessments. Results /UNASSIGNED: = .16), after adjusting for chance agreement. Conclusions /UNASSIGNED:Our results suggest that OSCE and direct observation tools provide different insights into resident communications skills (simulation of rare and challenging situations versus real-life daily encounters), and may provide useful perspectives on resident communications skills in different contexts.
PMCID:5901804
PMID: 29686764
ISSN: 1949-8357
CID: 3054442

Risk factors for recurrent instability or revision surgery following arthroscopic Bankart repair

Mahure, S A; Mollon, B; Capogna, B M; Zuckerman, J D; Kwon, Y W; Rokito, A S
Aims The factors that predispose to recurrent instability and revision stabilization procedures after arthroscopic Bankart repair for anterior glenohumeral instability remain unclear. We sought to determine the rate and risk factors associated with ongoing instability in patients undergoing arthroscopic Bankart repair for instability of the shoulder. Materials and Methods We used the Statewide Planning and Research Cooperative System (SPARCS) database to identify patients with a diagnosis of anterior instability of the shoulder undergoing arthroscopic Bankart repair between 2003 and 2011. Patients were followed for a minimum of three years. Baseline demographics and subsequent further surgery to the ipsilateral shoulder were analyzed. Multivariate analysis was used to identify independent risk factors for recurrent instability. Results A total of 5719 patients were analyzed. Their mean age was 24.9 years (sd 9.3); 4013 (70.2%) were male. A total of 461 (8.1%) underwent a further procedure involving the ipsilateral shoulder at a mean of 31.5 months (sd 23.8) postoperatively; 117 (2.1%) had a closed reduction and 344 (6.0%) had further surgery. Revision arthroscopic Bankart repair was the most common subsequent surgical procedure (223; 65.4%). Independent risk factors for recurrent instability were: age < 19 years (odds ratio 1.86), Caucasian ethnicity (hazard ratio 1.42), bilateral instability of the shoulder (hazard ratio 2.17), and a history of closed reduction(s) prior to the initial repair (hazard ratio 2.45). Revision arthroscopic Bankart repair was associated with significantly higher rates of ongoing persistent instability than revision open stabilization (12.4% vs 5.1%, p = 0.041). Conclusion The incidence of a further procedure being required in patients undergoing arthroscopic Bankart repair for anterior glenohumeral instability was 8.1%. Younger age, Caucasian race, bilateral instability, and closed reduction prior to the initial repair were independent risk factors for recurrent instability, while subsequent revision arthroscopic Bankart repair had significantly higher rates of persistent instability than subsequent open revision procedures. Cite this article: Bone Joint J 2018;100-B:324-30.
PMID: 29589497
ISSN: 2049-4408
CID: 3008952

Clinical Skills and Professionalism: Assessing Orthopaedic Residents With Unannounced Standardized Patients

Taormina, David P; Zuckerman, Joseph D; Karia, Raj; Zabar, Sondra; Egol, Kenneth A; Phillips, Donna P
OBJECTIVE: We developed a series of orthopedic unannounced standardized patient (USP) encounters for the purpose of objective assessment of residents during clinic encounters. DESIGN: Consecutive case-series. SETTING: NYU-Langone Multi-center Academic University Hospital System. PARTICIPANTS: NYU-Langone/Hospital for Joint Diseases Orthopedic Surgery residents; 48 consecutive residents assessed. METHODS: Four orthopedic cases were developed. USPs presented themselves as patients in outpatient clinics. Residents were evaluated on communication skills (information gathering, relationship development, and education and counseling). USPs globally rated whether they would recommend the resident. RESULTS: Forty-eight USP encounters were completed over a 2-year period. Communication skills items were rated at 51% (+/-30) "well done." Education and counseling skills were rated as the lowest communication domain at 33% (+/-33). Residents were globally recommended based on communication skills in 63% of the encounters recommended in 70% of encounters based on both professionalism and medical competence. CONCLUSIONS: The USP program has been useful in assessing residents' clinical skills, interpersonal and communications skills, and professionalism. Use of USP in orthopedic surgery training programs can be an objective means for trainee assessment.
PMID: 28888419
ISSN: 1878-7452
CID: 2702212

Multilevel glenoid morphology and retroversion assessmentinwalchb2 and b 3types [Meeting Abstract]

Samim, M; Virk, M; Zuckerman, J; Gyftopoulos, S
Purpose: As glenohumeral osteoarthritis progresses, there is increased risk for posterior glenoid bone loss which impacts an increasingly common treatment for these patients, total shoulder arthroplasty. Defining the level of maximum posterior bone loss and accurate assessment of its severity, using glenoid version measurements, are crucial to correctly align the glenoid prosthesis with glenoid to prevent prosthetic failure. While the importance of this information is clear, how these measurements should be performed remains in question with several techniques described in the literature. The purpose of this study was to define the most accurate level to measure glenoid version on CT for the most clinically relevant variants of posterior glenoid bone loss, Walch B2 and B3 types. Materials and Methods: 386 consecutive CT shoulder studies performed for shoulder arthroplasty preoperative planning between 2013- 2016 were retrospectively reviewed. Patients with B2 and B3 glenoid types were included. Two radiologists measured glenoid retroversion independently according to Friedman method on true axial CT images using the "intermediate glenoid line", at three glenoid heights: 25% (upper) 50% (equator) and 75% (lower). Results: 29 B2 and 8 B3 glenoid types were included. There was no statistically significant difference found in the retroversion measurements performed by each reader at the three glenoid levels on the B2 or B3 glenoid types (Mean angles (%) in upper, equator and lower in B2: 16.5, 17,0 and 17.5 and B3: 20.6, 20.7 and 23.2, respectively). There was substantial inter-reader correlation (r>=0.7) in angle measurements. Conclusion: Our study suggests that glenoid version can be accurately measured at any level between 25%-75%of the glenoid height forWalch B2 and B3 types. We recommend that the glenoid equator be used as the reference in order to assure consistent and reliable version measurements in this group of patients
EMBASE:620615481
ISSN: 1432-2161
CID: 2959312

Topical vancomycin and its effect on survival and migration of osteoblasts, fibroblasts, and myoblasts: An in vitro study

Liu, James X; Bravo, Dalibel; Buza, John; Kirsch, Thorsten; Kennedy, Oran; Rokito, Andrew; Zuckerman, Joseph D; Virk, Mandeep S
The purpose of this study was to examine the influence of topical vancomycin on cell migration and survival of tissue healing cells. Human osteoblasts, myoblasts and fibroblasts were exposed to vancomycin at concentrations of 1, 3, 6, or 12 mg/cm2 for either a 1-h or 48-h (continuous) duration. Continuous exposure to all vancomycin concentrations significantly reduced cell survival (<22% cells survived) and migration in osteoblasts and myoblasts (P < 0.001). 1-h vancomycin exposure reduced osteoblast and myoblast survival and migration only at 12 mg/cm2 (P < 0.001). Further in vivo studies are warranted to optimize the dosage of intrawound vancomycin.
PMCID:5895903
PMID: 29657439
ISSN: 0972-978x
CID: 3040782

Diagnostic utility of lavage for periprosthetic joint infection: Are the culture results reliable? [Meeting Abstract]

Lin, D; Burke, C; Jia, N; Zuckerman, J; Ciavarra, G
Purpose: Image-guided joint aspiration is often requested for clinically suspected periprosthetic joint infection (PJI). For "dry taps" when no native joint fluid can be aspirated, a lavage with non-bacteriostatic saline can be performed. The purpose of this study is to determine the diagnostic utility of lavage versus native joint fluid aspiration in the setting of clinically suspected PJI. Materials and Methods: IRB approval was obtained and informed consent was waived for this retrospective study. A PACS search from 2011- 2017 for image-guided aspirations yielded 918 procedures, of which 630 were excluded for non-articular and non-arthroplasty aspirations, antibiotic cement spacers, and lack of clinical information in the electronic medical record. The study cohort included 288 procedures from 173 patients who underwent operative or non-operative management. The reference standard was the intraoperative culture for operative patients and clinical follow-up for conservatively managed patients. A Fisher exact test was used for statistical analysis. Results: The study cohort consisted of 98 females, 75 males, mean age 64 (range 34-90) with the following arthroplasty types: 176 hips, 65 knees, and 47 shoulders. Of 288 procedures, 105 were performed with lavage and 183 were native joint fluid aspirations; 112 were subsequently operatively managed. The mean follow-up for non-operative patients was 5 months (range 0-42). For native joint fluid aspiration versus lavage, accuracy was 81% vs. 73% (p=0.14), sensitivity was 58% vs. 28% (p=0.03), specificity was 88% vs. 91% (p=0.66), negative predictive value was 89% vs. 77% (p=0.02), and positive predictive value was 55% vs. 53% (p=1.00), respectively. Conclusion: Lavage is less sensitive with a lower negative predictive value for the diagnosis of PJI compared to native joint fluid aspirations, possibly due to a lower pretest probability of infection and the inherent dilutional effects of the procedure
EMBASE:620615492
ISSN: 1432-2161
CID: 2959292

Quantifying success after total shoulder arthroplasty: the minimal clinically important difference

Simovitch, Ryan; Flurin, Pierre-Henri; Wright, Thomas; Zuckerman, Joseph D; Roche, Christopher P
BACKGROUND:Knowledge of the minimal clinically important difference (MCID) for different shoulder outcome metrics and range of motion after total shoulder arthroplasty (TSA) can be useful to establish a minimum threshold of improvement that defines successful treatment. This study quantifies how MCID varies with different prosthesis types, patient age, gender, and length of follow-up after TSA. METHODS:A total of 466 anatomic TSA (aTSA) and reverse TSA (rTSA) with 2-year minimum follow-up were performed by 13 shoulder surgeons. The MCID for the American Shoulder and Elbow Surgeons, Constant, University of California Los Angeles Shoulder Rating Scale, Simple Shoulder Test, Shoulder Pain and Disability Index, global shoulder function, and visual analog scale for pain scores, as well as active abduction, forward flexion, and external rotation, were calculated for different prosthesis types and patient cohorts using an anchor-based method. RESULTS:The anchor-based MCID results were American Shoulder and Elbow Surgeons = 13.6 ± 2.3, Constant score = 5.7 ± 1.9, University of California Los Angeles Shoulder Rating Scale = 8.7 ± 0.6, Simple Shoulder Test score = 1.5 ± 0.3, Shoulder Pain and Disability Index score = 20.6 ± 2.6, global shoulder function = 1.4 ± 0.3, pain visual analog scale  = 1.6 ± 0.3, active abduction = 7° ± 4°, active forward flexion = 12° ± 4°, and active external rotation = 3° ± 2°. Female gender and rTSA were associated with lower MCID values compared with male gender and aTSA patients. CONCLUSION/CONCLUSIONS:The minimum improvement necessary for patients to achieve a result they believe is clinically meaningful after aTSA and rTSA is nominal and was achieved by at least 80% of the patients. Future endeavors should investigate the influence of different anchor questions on the MCID calculation.
PMID: 29162305
ISSN: 1532-6500
CID: 2907712

Personality Factors Associated With Resident Performance: Results From 12 Accreditation Council for Graduate Medical Education Accredited Orthopaedic Surgery Programs

Phillips, Donna; Egol, Kenneth A; Maculatis, Martine C; Roloff, Kathryn S; Friedman, Alan M; Levine, Brett; Garfin, Steven; Schwartz, Alexandra; Sterling, Robert; Kuivila, Thomas; Paragioudakis, Steve J; Zuckerman, Joseph D
OBJECTIVES/OBJECTIVE:To understand the personality factors associated with orthopedic surgery resident performance. DESIGN/METHODS:A prospective, cross-sectional survey of orthopedic surgery faculty that assessed their perceptions of the personality traits most highly associated with resident performance. Residents also completed a survey to determine their specific personality characteristics. A subset of faculty members rated the performance of those residents within their respective program on 5 dimensions. Multiple regression models tested the relationship between the set of resident personality measures and each aspect of performance; relative weights analyses were then performed to quantify the contribution of the individual personality measures to the total variance explained in each performance domain. Independent samples t-tests were conducted to examine differences between the personality characteristics of residents and those faculty identified as relevant to successful resident performance. SETTING/METHODS:throughout the United States. The level of clinical care provided by participating institutions varied. PARTICIPANTS/METHODS:Data from 175 faculty members and 266 residents across 12 programs were analyzed. RESULTS:The personality features of residents were related to faculty evaluations of resident performance (for all, p < 0.01); the full set of personality measures accounted for 4%-11% of the variance in ratings of resident performance. Particularly, the characteristics of agreeableness, neuroticism, and learning approach were found to be most important for explaining resident performance. Additionally, there were significant differences between the personality features that faculty members identified as important for resident performance and the personality features that residents possessed. CONCLUSION/CONCLUSIONS:Personality assessments can predict orthopedic surgery resident performance. However, results suggest the traits that faculty members value or reward among residents could be different from the traits associated with improved resident performance.
PMID: 28688967
ISSN: 1878-7452
CID: 2984222

Cytotoxicity evaluation of chlorhexidine gluconate on human fibroblasts, myoblasts, and osteoblasts

Liu, James X; Werner, Jordan; Kirsch, Thorsten; Zuckerman, Joseph D; Virk, Mandeep S
Introduction: Chlorhexidine gluconate (CHX) is widely used as a preoperative surgical skin-preparation solution and intra-wound irrigation agent, with excellent efficacy against wide variety of bacteria. The cytotoxic effect of CHX on local proliferating cells following orthopaedic procedures is largely undescribed. Our aim was to investigate the in vitro effects of CHX on primary fibroblasts, myoblasts, and osteoblasts. Methods: Cells were exposed to CHX dilutions (0%, 0.002%, 0.02%, 0.2%, and 2%) for either a 1, 2, or 3-minute duration. Cell survival was measured using a cytotoxicity assay (Cell Counting Kit-8). Cell migration was measured using a scratch assay: a "scratch" was made in a cell monolayer following CHX exposure, and time to closure of the scratch was measured. Results: All cells exposed to CHX dilutions of ≥ 0.02% for any exposure duration had cell survival rates of less than 6% relative to untreated controls (p < 0.001). Cells exposed to CHX dilution of 0.002% all had significantly lower survival rates relative to control (p < 0.01) with the exception of 1-minute exposure to fibroblasts, which showed 96.4% cell survival (p = 0.78). Scratch defect closure was seen in < 24 hours in all control conditions. However, cells exposed to CHX dilutions ≥ 0.02% had scratch defects that remained open indefinitely. Conclusions: The clinically used concentration of CHX (2%) permanently halts cell migration and significantly reduces survival of in vitro fibroblasts, myoblasts, and osteoblasts. Further in vivo studies are required to examine and optimize CHX safety and efficacy when applied near open incisions or intra-wound application.
PMCID:6098817
PMID: 30155401
ISSN: 2206-3552
CID: 3255952