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Surgical Management of Ulcerative Colitis

Grieco, Michael J; Remzi, Feza H
Ulcerative colitis can be managed by surgical resection of the colon and rectum. The final reconstruction options of traditional end ileostomy, continent ileostomy, ileorectal anastomosis, or ileal pouch anal anastomosis (IPAA). We maintain that the IPAA is the gold standard management of ulcerative colitis and should be performed in stages. This article includes descriptions of technique, management alternatives, and intraoperative and postoperative management of pouch issues.
PMID: 33121694
ISSN: 1558-1942
CID: 4646812

S-pouch to the Rescue - video vignette [Letter]

Aydinli, H Hande; Grieco, Michael; Kirat, Hasan T; Remzi, Feza H
Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the operation of choice for patients with ulcerative colitis (UC). The most common type of IPAA is a J-pouch. If despite all other mobilization maneuvers, inadequate mesenteric reach prevents a tension free anastomosis with J-pouch, a good alternative is S-pouch creation, which can provide an additional 2 to 4 cm of length (1). This article is protected by copyright. All rights reserved.
PMID: 31090991
ISSN: 1463-1318
CID: 3919732

Is the whole world watching and waiting? An International Questionnaire on the current practices of 'Watch & Wait' rectal cancer treatment

Schwartzberg, David M; Grieco, Michael J; Timen, Micah; Grucela, Alexis L; Bernstein, Mitchell A; Wexner, Steven D
PMID: 30506653
ISSN: 1463-1318
CID: 3520202

30-day readmission after ileal pouch anal anastomosis surgery: A report from ACS-NSQIP database [Meeting Abstract]

Hande, A H; Lynn, P; Aytac, E; Grieco, M; Remzi, F
Background: Ileal pouch anal anastomosis (IPAA) is the preferred surgical option in patients with medically refractory ulcerative colitis (UC) to preserve gastrointestinal continuity. Tis study aimed to describe 30-day readmission rates, as well as predictive factors for it from a national dataset. METHODS: Patients who underwent IPAA surgery for UC between 2012 and 2015 were identifed from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database using current procedural terminology codes. Demographics, perioperative, and operative variables were collected. Patients were grouped according to the presence of 30-day readmission: (+)/(-). RESULTS: Query identifed 1882 patients, mean age was 40.8+/- 13.9 years, mean length of stay was 7.2+/- 5 days and postoperative 30-day morbidity rate was 28% (n=530). Most common complications in the study group were transfusion (7.5%), organ space surgical site infection (SSI) (3.3%), reoperation (3%) and superfcial SSI (2%). Twenty-two percent (n=416) were readmitted within 30 days of surgery. Reasons for readmission were: surgical site infection (n=88), dehydration (n=77), small bowel obstruction/ileus (n=38/18) and abdominal pain (n=28). Mean time for readmission was 14+/- 7 days, 39 patients had second readmission and 4 had a third readmission within 30-days of surgery. Multivariate analysis showed an ASA score of 4 [OR: 14.4 (2.3-89.7), P=0.004] and age<40 [OR: 1.3 (1.08-1.7), P=0.006] were associated with 30-day readmission. Preoperative albumin level of <3.5 was associated with a second readmission [OR:3 (1.1-8.2), P=0.02)]. CONCLUSION(S): IPAA surgery for UC has high morbidity. One ffh of patients were readmitted within 30 days from IPAA surgery for UC and one third of them had a second readmission. Tis study brings the possibility and consideration for national health care initiative in surgical management of patients with UC, undergoing IPAA surgery
EMBASE:621500968
ISSN: 1572-0241
CID: 3113202

A QUESTIONNAIRE ON THE CURRENT PRACTICES OF "WATCH & WAIT" RECTAL CANCER TREATMENT FROM AMERICAN SOCIETY OF COLON AND RECTAL SURGEONS, EUROPEAN SOCIETY OF COLOPROCTOLOGY, ASSOCIATION OF COLOPROCTOLOGY OF GREAT BRITAIN AND IRELAND, COLORECTAL SURGICAL SOCIETY OF AUSTRALIA AND NEW ZEALAND & BRAZILIAN SOCIETY OF COLOPROCTOLOGY. [Meeting Abstract]

Schwartzberg, D.; Wexner, S.; Grucela, A.; Bernstein, M.; Grieco, M.; Timen, M.
ISI:000401172800472
ISSN: 0012-3706
CID: 3256322

THE TANDEM IMPACT OF AN ELECTRONIC HEALTH RECORD-INTEGRATED COLON PATHWAY AND A TARGETED SURGICAL SITE REDUCTION PROTOCOL ON SURVIVAL SITE INFECTION RATES. [Meeting Abstract]

Schwartzberg, D.; Cahan, E.; Grieco, M.; Grucela, A.; Bernstein, M.
ISI:000401172800177
ISSN: 0012-3706
CID: 3256312

AN ELECTRONIC HEALTH RECORD-INTEGRATED COLON PATHWAY: EXAMINING VARIABLE DIRECT COST, OVERALL SAVINGS AND REDUCTION IN LENGTH OF STAY. [Meeting Abstract]

Schwartzberg, D.; Cahan, E.; Grieco, M.; Grucela, A.; Bernstein, M.
ISI:000401172800176
ISSN: 0012-3706
CID: 3256302

Catastrophic systemic embolism resulting from spontaneous pulmonary vein thrombosis with extension into the left atrium in a patient with Crohn's disease [Meeting Abstract]

Lowe, S C; Pitman, M; Grieco, M; Malter, L B
Patients with inflammatory bowel disease (IBD) are well known to be at increased risk of venous thromboembolism. Systemic thrombotic events are rare, but likely more common among IBD patients as well. We describe a case of Crohn's colitis complicated by spontaneous pulmonary vein thrombosis eventually resulting in systemic embolism and acute mesenteric ischemia. A 25-year-old female with stricturing Crohn's colitis presented to the emergency department with one week of back pain and pleuritic chest pain. She was initially diagnosed with Crohn's disease three years prior, when she presented with large bowel obstruction requiring emergent transverse colostomy. Infliximab was begun after surgery, and she achieved complete clinical remission. She continued to feel well until the present illness. Upon hospital admission, a computed tomography (CT) scan revealed multiple right sided pulmonary emboli as well as a large pulmonary vein thrombus extending into the left atrium. Echocardiogram revealed no evidence of right heart strain. Anticoagulation was initiated with unfractionated heparin, and the patient was eventually transitioned to apixaban. On the evening prior to anticipated discharge, she developed sudden onset fever and epigastric pain. A CT scan of the abdomen revealed acute thrombosis of the superior mesenteric artery. The patient underwent emergent laparotomy with thrombectomy, initially without small bowel resection. Subsequent second-look laparotomy revealed 75cm of ischemic small bowel, which was resected. The patient continued to have fever and abdominal pain, however, and further exploration revealed necrosis of the entire remaining small bowel, which was resected leaving only a duodenal stump. The patient was eventually transferred to another center for consideration of intestinal transplant. Pulmonary vein thrombosis is an extremely rare condition usually precipitated by intrathoracic neoplasm or thoracic surgery, particularly lung transplantation. There is an associated risk of pulmonary hypertension as well as systemic arterial embolization. To our knowledge, this is the first reported case of spontaneous pulmonary vein thrombosis with IBD as the inciting factor. Due to the risk of catastrophic complications from systemic embolism, rapid diagnosis and treatment are essential. Anticoagulation alone may not be sufficient in all cases, and thrombectomy may be considered if the thrombus does not resolve with medical management
EMBASE:620839789
ISSN: 1572-0241
CID: 2968132

Morbidity associated with colectomy for cecal volvulus: A nationwide analysis [Meeting Abstract]

Aydinli, H H; Aytac, E; Grieco, M J; Keshinro, A; Bernstein, M A; Remzi, F H
INTRODUCTION: The aim of this study was to evaluate 30-day postoperative morbidity in patients undergoing colectomy for cecal volvulus. METHODS: Patients who underwent surgery for cecal volvulus between 2012 and 2015 were identified from the American College of Surgeons-NSQIP by using current procedural terminology codes and ICD-9 code. Demographics, perioperative, and operative factors were assessed and compared between 2 groups, which were classified according to the presence or absence of postoperative morbidity. RESULTS: A total of 591 patients were identified with a mean age of 61.8 (range 18-89) of which 74% were female. Forty-three percent of patients had postoperative complications and 3% of patients died within 30 days of surgery. Most common postoperative complication was ileus (23%) followed by transfusion (10%) and superficial surgical site infection (8%). Mean length of stay was 8.5 days >=days and 9% of patients were readmitted within 30 days of surgery. African American (AA) race (odds ratio [OR]: 2.3, p=0.03), preoperative septic status (OR: 1.8, p=0.04) and wound class of 3-4 (OR: 1.9, p=0.01) were associated with 30-day postoperative morbidity. Length of stay (5.7+/- 2.6 vs 12.2+/- 10, p<0.0001) was longer and readmission rates (11 (3.2) vs 44 (17.1), p<0.0001) were higher among the patents with postoperative morbidity. CONCLUSIONS: Thirty-day postoperative morbidity in patients who underwent colectomy for cecal volvulus is high with a longer length of stay. Severity of infection seems strictly related to postoperative morbidity and individualized patient care can be designed based on the extent of infection in these patients
EMBASE:619489785
ISSN: 1879-1190
CID: 2862042

Anal Canal Neoplasia

Chapter by: Schwartzberg, David; Grieco, M
in: Clinical Decision Making in Colorectal Surgery by Steele, Scott R; Maykel, Justin, Wexner, Steven D (Eds)
[S.l.] : Springer, 2016
pp. ?-?
ISBN: 978-3-319-65941-1
CID: 3256352