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Bosniak classification of cystic renal masses, version 2019: interpretation pitfalls and recommendations to avoid misclassification

Edney, Elizabeth; Davenport, Matthew S; Curci, Nicole; Schieda, Nicola; Krishna, Satheesh; Hindman, Nicole; Silverman, Stuart G; Pedrosa, Ivan
The purpose of this review is to describe the potential sources of variability or discrepancy in interpretation of cystic renal masses under the Bosniak v2019 classification system. Strategies to avoid these pitfalls and clinical examples of diagnostic approaches are also presented. Potential pitfalls in the application of Bosniak v2019 are divided into three categories: interpretative, technical, and mass related. An organized, comprehensive review of possible discrepancies in interpreting Bosniak v2019 cystic masses is presented with pictorial examples of difficult clinical cases and proposed solutions. The scheme provided can guide readers to consistent, precise application of the classification system. Radiologists should be aware of the possible sources of misinterpretation of cystic renal masses when applying Bosniak v2019. Knowing which features and types of cystic masses are prone to interpretive errors, in addition to the inherent trade-offs between the CT and MR techniques used to characterize them, can help radiologists avoid these pitfalls.
PMID: 33484283
ISSN: 2366-0058
CID: 4799502

Update on MRI of Cystic Renal Masses Including Bosniak Version 2019

Krishna, Satheesh; Schieda, Nicola; Pedrosa, Ivan; Hindman, Nicole; Baroni, Ronaldo H; Silverman, Stuart G; Davenport, Matthew S
Incidental cystic renal masses are common, usually benign, and almost always indolent. Since 1986, the Bosniak classification has been used to express the risk of malignancy in a cystic renal mass detected at imaging. Historically, magnetic resonance imaging (MRI) was not included in that classification. The proposed Bosniak v.2019 update has formally incorporated MRI, included definitions of imaging terms designed to improve interobserver agreement and specificity for malignancy, and incorporated a variety of masses that were incompletely defined or not included in the original classification. For example, at unenhanced MRI, homogeneous masses markedly hyperintense at T2 -weighted imaging (similar to cerebrospinal fluid) and homogeneous masses markedly hyperintense at fat suppressed T1 -weighted imaging (approximately ≥2.5 times more intense than adjacent renal parenchyma) are classified as Bosniak II and may be safely ignored, even when they have not been imaged with a complete renal mass MRI protocol. MRI has specific advantages and is recommended to evaluate masses that at computed tomography (CT) 1) have abundant thick or nodular calcifications; 2) are homogeneous, hyperattenuating, ≥3 cm, and nonenhancing; or 3) are heterogeneous and nonenhancing. Although MRI is generally excellent for characterizing cystic renal masses, there are unique weaknesses of MRI that bear consideration. These details and others related to MRI of cystic renal masses are described in this review, with an emphasis on Bosniak v.2019. A website (https://bosniak-calculator.herokuapp.com/) and mobile phone apps named "Bosniak Calculator" have been developed for ease of assignment of Bosniak classes. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY STAGE: 3.
PMID: 33009722
ISSN: 1522-2586
CID: 4651752

Current State of Membership Diversity Among North American Radiology Societies: Analysis of Public Information on Society Websites

Prabhu, Vinay; Pascual Van Sant, Eduardo; Lovett, Jessica T; Hindman, Nicole M
RATIONALE AND OBJECTIVES/OBJECTIVE:Diversity is an identified priority amongst governing medical bodies. We systematically analyzed public membership diversity data posted by North American radiology societies. MATERIALS AND METHODS/METHODS:Two independent study members reviewed North American radiology society websites to collect public data on membership diversity, specifically related to gender, race, and sexual orientation or gender identity, and categorized data using a coding system. Supplemental searches were conducted to confirm findings. Study team members created accounts on each society website to identify whether diversity data was collected during member enrollment. RESULTS:We reviewed a total of 26 society websites, with median 1500 members (range 110-54,600). We categorized five societies as "diversity leaders" based on having diversity statement(s), diversity initiatives, and diversity publication(s). While 62%, 8%, and 0% of societies collected data on gender, race, and sexual orientation or gender identity, respectively, no societies posted membership composition of these groups. Fourty-six percent of societies had membership diversity statement(s) on their webpages. Fifty-four percent had initiative(s) targeted at diversity (23% had multiple). Fifty percent had membership diversity publication(s). Sexual orientation and gender identity minority members were least frequently specified as beneficiaries of diversity statements, initiatives, and publications. Societies with larger memberships were more likely to have membership diversity initiatives (p = 0.01), journal articles on membership diversity (p = 0.005), and be "diversity leaders" (p = 0.02). CONCLUSION/CONCLUSIONS:Public support of membership diversity by many North American radiology societies, especially those with fewer members, is lacking. Identified "diversity leaders" can serve as models for societies aiming to establish their commitment to diversity.
PMID: 32771316
ISSN: 1878-4046
CID: 4615022

Changing National Medicare Utilization of Catheter, Computed Tomography, and Magnetic Resonance Extremity Angiography: A Specialty-focused 16-Year Analysis

Guichet, Phillip L; Duszak, Richard; Chaves Cerdas, Laura; Hughes, Danny R; Hindman, Nicole; Rosenkrantz, Andrew B
To assess changing utilization of extremity angiography from 2001 to 2016, focusing on modalities and provider specialties. Medicare PSPS Master Files from 2001-2016 and POSPUF from 2016 were used to determine overall and specialty utilization of diagnostic catheter angiography (DCA), CT angiography (CTA), and MR angiography (MRA). From 2001 to 2016, extremity angiography increased from 1107 to 1590 extremities imaged per 100,000 beneficiaries, with rapid expansion of CTA (22 in 2001 to 619 in 2009; plateau of 645 in 2016), but declines in DCA (1039 to 914) and MRA (45 to 30). Over time, extremity angiography shifted from 94% DCA, 4% MRA, and 2% CTA to 58% DCA, 41% CTA, and 2% MRA. For radiologists, extremity angiography increased slightly (741 to 767) with increases in CTA (20 to 595) and large decreases in DCA (681 to 145), with MRA remaining low (40 to 27). Extremity angiography increased for cardiologists (197 to 349) and vascular surgeons (87 to 351), both overwhelmingly performing DCA. Radiologists' share of all extremity angiography shifted from 67% to 48%, with interventionalists (47%), generalists (43%), and abdominal radiologists (7.4%) providing most radiologist services in 2016. Throughout, radiologists were the dominant providers of CTA (89% to 92%) and MRA (89% to 90%). Extremity angiography utilization in Medicare beneficiaries increased nearly 50% from 2001 to 2016, largely related to CTA performed by radiologists. Of radiologists, interventionalists and generalists together render most services. Cardiologists and surgeons assumed a large share of DCA previously performed by radiologists.
PMID: 32029351
ISSN: 1535-6302
CID: 4300622

ACR Appropriateness Criteria® Liver Lesion-Initial Characterization

Chernyak, Victoria; Horowitz, Jeanne M; Kamel, Ihab R; Arif-Tiwari, Hina; Bashir, Mustafa R; Cash, Brooks D; Farrell, James; Goldstein, Alan; Grajo, Joseph R; Gupta, Samir; Hindman, Nicole M; Kamaya, Aya; McNamara, Michelle M; Porter, Kristin K; Solnes, Lilja Bjork; Srivastava, Pavan K; Zaheer, Atif; Carucci, Laura R
Incidental liver masses are commonly identified on imaging performed for other indications. Since the prevalence of benign focal liver lesions in adults is high, even in patients with primary malignancy, accurate characterization of incidentally detected lesions is of paramount clinical importance. This document reviews utilization of various imaging modalities for characterization of incidentally detected liver lesions, discussed in the context of several clinical scenarios. For each clinical scenario, a summary of current evidence supporting the use of a given diagnostic modality is reported. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 33153555
ISSN: 1558-349x
CID: 4668662

Spectrum of imaging findings in gender-affirming genital surgery: Intraoperative photographs, normal post-operative anatomy, and common complications

Nazarian, Matthew; Bluebond-Langner, Rachel; Smereka, Paul; Zhao, Lee; Ream, Justin; Hindman, Nicole
Gender-affirming surgery is becoming more accessible, and radiologists must be familiar with both terminology and anatomy following gender-affirming surgical procedures. This essay will review the most common gender-affirming genital surgeries, their post-operative anatomy, and common complications by providing intraoperative photographs, illustrations, and cross-sectional images. Routine radiologic imaging recommendations for transgender patients will also be reviewed.
PMID: 32659682
ISSN: 1873-4499
CID: 4538582

One-Stop Shopping: Dual-Energy CT for the Confident Diagnosis of Adrenal Adenomas [Comment]

Hindman, Nicole M; Megibow, Alec J
PMID: 32452734
ISSN: 1527-1315
CID: 4481952

ACR Appropriateness Criteria® Pancreatic Cyst

Fábrega-Foster, Kelly; Kamel, Ihab R; Horowitz, Jeanne M; Arif-Tiwari, Hina; Bashir, Mustafa R; Chernyak, Victoria; Goldstein, Alan; Grajo, Joseph R; Hindman, Nicole M; Kamaya, Aya; McNamara, Michelle M; Porter, Kristin K; Scheiman, James M; Solnes, Lilja Bjork; Srivastava, Pavan K; Zaheer, Atif; Carucci, Laura R
Incidental pancreatic cysts are increasingly detected on imaging studies performed for unrelated indications and may be incompletely characterized on these studies. Adequate morphological characterization is critical due to the small risk of malignant degeneration associated with neoplastic pancreatic cysts, as well as the risk of associated pancreatic adenocarcinoma. For all pancreatic cysts, both size and morphology determine management. Specifically, imaging detection of features, such as pancreatic ductal communication and presence or absence of worrisome features or high-risk stigmata, have important management implications. The recommendations in this publication determine the appropriate initial imaging study to further evaluate a pancreatic cyst that was incidentally detected on a nondedicated imaging study. The recommendations are designed to maximize the yield of diagnostic information in order to better risk-stratify pancreatic cysts and assist in guiding future management. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 32370963
ISSN: 1558-349x
CID: 4422372

ACR Appropriateness Criteria® Chronic Liver Disease

Bashir, Mustafa R; Horowitz, Jeanne M; Kamel, Ihab R; Arif-Tiwari, Hina; Asrani, Sumeet K; Chernyak, Victoria; Goldstein, Alan; Grajo, Joseph R; Hindman, Nicole M; Kamaya, Aya; McNamara, Michelle M; Porter, Kristin K; Solnes, Lilja Bjork; Srivastava, Pavan K; Zaheer, Atif; Carucci, Laura R
The liver fibrosis stage is the most important clinical determinate of morbidity and mortality in patients with chronic liver diseases. With newer therapies, liver fibrosis can be stabilized and possibly reversed, thus accurate diagnosis and staging of liver fibrosis are clinically important. Ultrasound, CT, and conventional MRI can be used to establish the diagnosis of advanced fibrosis/cirrhosis but have limited utility for assessing earlier stages of fibrosis. Elastography-based ultrasound and MRI techniques are more useful for assessment of precirrhotic hepatic fibrosis. In patients with advanced fibrosis at risk for hepatocellular carcinoma (HCC), ultrasound is the surveillance modality recommended by international guidelines in nearly all circumstances. However, in patients in whom ultrasound does not assess the liver well, including those with severe steatosis or obesity, multiphase CT or MRI may have a role in surveillance for HCC. Both multiphase CT and MRI can be used for continued surveillance in patients with a history of HCC, and contrast-enhanced ultrasound may have an emerging role in this setting. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 32370979
ISSN: 1558-349x
CID: 4422382

Medical management of endometriosis: what the radiologist needs to know

Hindman, Nicole; Eswar, Christopher; Huang, Kathy; Tong, Angela
The role of the radiologist in the diagnosis and management of patients with endometriosis is increasing. Improvement in MRI imaging techniques has improved detection rate of subtle manifestations of endometriosis by radiologists. Therefore, the role of imaging in the diagnosis and follow-up after treatment is also likely to increase. Knowledge of new medical management pathways used in treating patients with endometriosis-related pain is important. The knowledge of various medication regimens will allow radiologists to continue to evaluate baseline disease, and to potentially assess for imaging response/stability to these medications. This article will review the current medical therapies in use in the management of endometriosis-related pain and describe potential imaging-related findings expected with these therapies.
PMID: 32270260
ISSN: 2366-0058
CID: 4378972