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Refinement and validation of the urethral stricture score in categorizing anterior urethral stricture complexity
Eswara, Jairam R; Han, Justin; Raup, Valary T; Dielubanza, Elodi; Gonzalez, Christopher M; Vetter, Joel M; Brandes, Steven B
OBJECTIVE:To update, simplify, and validate the UREThRAL Stricture Score (now called the U-score) for anterior urethral strictures, with the goal of using this system as a predictor of surgical complexity. METHODS:This is a retrospective review of 102 patients (test set) who underwent anterior urethroplasty at Barnes-Jewish Hospital from 2009 to 2012 and a validation set of 96 patients from Northwestern University. The U-score was based on length (1-3 points), stricture number (1-2 points), location (1-2 points), and etiology (1-2 points) for a total ranging from 4 to 9. Excision and primary anastomosis, buccal mucosal graft, and augmented anterior urethroplasty were classified as low complexity, and double buccal mucosal graft, flap, or flap-graft combo were classified as high complexity. Operative time and estimated blood loss were used as surrogates of surgical complexity. RESULTS:Mean U-score for low-complexity surgeries was 5.2 and for high complexity surgeries was 7.3. Factors that were associated with high-complexity repairs included stricture etiology (trauma or idiopathic or iatrogenic vs inflammatory or hypospadias; P ≤.0001), number (1 vs. >1; P = .003), location (penile vs. bulbar; P <.001), and length (<2 vs. 2-5 vs. >5 cm; P <.001). Increasing U-score correlated with increasing surgical complexity (P ≤.0001). A linear relationship between U-score and operative time was observed (P = .0018). U-score did not correlate with estimated blood loss (P = .82). Among the validation data set, etiology (P = .0014), location (P ≤.0001), stricture length (P ≤.0001), and overall U-score (P ≤.0001) correlated with surgical complexity. CONCLUSION/CONCLUSIONS:The U-score is a validated scale to describe the complexity of anterior urethral strictures that correlates with surgical time and complexity of procedure.
PMID: 25559728
ISSN: 1527-9995
CID: 4994252
Testicular Interposition Flap for Repair of Perineal Urinary Fistulae: A Novel Surgical Technique
Raup, Valary T; Eswara, Jairam R; Marshall, Stephen D; Brandes, Steven B
Rectourinary fistulae and urinary-cutaneous fistulae are a rare yet devastating complication. Current options for tissue interposition include rectus, gracilis, or gluteal muscle, omentum, or intestine for use in coloanal pull-through procedures. In elderly patients, testicular interposition flaps may be an excellent tissue option to use when vitalized tissue is necessary to supplement fistula repair. Elderly patients frequently have increased spermatic cord length, potentially offering a longer flap reach than use of a muscle flap. Additionally, mobilizing one of the testicles and developing it through the external inguinal ring may be a less morbid and less costly procedure than harvesting and tunneling a muscle flap. Longer follow-up and further studies are needed to determine the outcomes of this novel technique.
PMCID:4592900
PMID: 26483985
ISSN: 2090-696x
CID: 4994342
Seminoma presenting as renal mass, inferior vena caval thrombus, and regressed testicular mass
Raup, Valary T; Johnson, Michael H; Weese, Jonathan R; Hagemann, Ian S; Marshall, Stephen D; Brandes, Steven B
Testicular cancer is the most common malignancy of men aged 15-40. Metastatic spread classically begins with involvement of the retroperitoneal lymph nodes, with metastases to the liver, lung, bone, and brain representing advancing disease. Treatment is based on pathologic analysis of the excised testicle and presence of elevated tumor markers. We report a case of a 34-year-old male presenting with back pain who was found to have a right renal mass with tumor extension into the inferior vena cava. Subsequent biopsy was consistent with seminoma. We review this rare case and discuss the literature regarding its diagnosis and management.
PMCID:4325215
PMID: 25705542
ISSN: 2090-696x
CID: 4994262
The pitfalls of electronic health orders: development of an enhanced institutional protocol after a preventable patient death
Manley, Brandon J; Gericke, Rebecca K; Brockman, John A; Robles, Jennifer; Raup, Valary T; Bhayani, Sam B
BACKGROUND:Continuous bladder irrigation (CBI) is a long-standing treatment used in the setting of gross hematuria and other acute bladder issues. Its use has traditionally been reserved for patients under direct urologic care, but with the constraints of modern large-hospital healthcare, many patients have CBI administered by providers unfamiliar with its use and potential complications. FINDINGS/RESULTS:There were 136 CBI orders placed in 2013 by non-urologic providers. The biggest hazard found in our analysis was the requirement for entering a rate of irrigation administration. Nurses with no experience with CBI viewed this order as an indication to administer via an infusion pump, which can easily exceed the mechanical integrity of the bladder and increase the risk of bladder perforation. Our panel also found that due to lack of experience by nurses and non-urologic providers, that signs and symptoms of CBI dysfunction were not common knowledge. Also we found that non-urologic providers were unfamiliar with administration and dosing of medications for CBI patients to help with the intrinsic discomfort with CBI administration. CONCLUSIONS:In our revised order set we found that removing the requirement for an infusion rate, along with placing warnings in the CPOE, helped staff better understand this possible complication. We created a best practice alert in our CPOE to strongly recommend the urology service be consulted. Communication text boxes were added to the order set to help staff be aware of the signs and symptoms of CBI dysfunction, along with a guide for trouble shooting.
PMCID:4193978
PMID: 25309624
ISSN: 1754-9493
CID: 4994242