Faculty Bibliography
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Total Results:
204
Drug delivery and toxicity of adjuvant chemotherapy for non-small cell lung cancer (NSCLC): Washington University experience [Letter]
PMID: 17653916
ISSN: 0284-186x
CID: 3237392
Clinical utility of routinely adding positron emission tomography (PET) to computer tomography (CT) and endoscopic ultrasound (EUS) in the initial staging of esophageal carcinoma: The Washington University in St. Louis experience [Meeting Abstract]
ISI:000241288000085
ISSN: 0012-3692
CID: 3237962
Insulin-like growth factor and lung cancer
Lung cancer is the leading cause of cancer-related death in the United States. Despite the availability of several cytotoxic and a few molecularly targeted agents, the outlook for patients with advanced non-small cell lung cancer continues to be dismal. Novel approaches are desperately needed. The insulin-like growth factor (IGF) pathway plays an important role in a number of human malignancies contributing to unregulated cell proliferation. The IGF pathway has several targets for therapeutic intervention. Preclinical studies of IGF inhibitors have demonstrated synergism when combined with chemotherapy agents and radiation. Clinical studies are currently ongoing to investigate the safety and efficacy of IGF inhibitors in combination with chemotherapy agents. In this review, we discuss the biology of the IGF pathway and various potential targets for therapy.
PMID: 17409926
ISSN: 1556-1380
CID: 3237362
The proportion of patients with metastatic non-small cell lung cancer potentially eligible for treatment with bevacizumab: a single institutional survey [Letter]
PMID: 17409907
ISSN: 1556-1380
CID: 3237352
