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The management of patients with dysplastic and congenital nevi
Rigel DS; Friedman RJ
Although both dysplastic and congenital nevi appear to have a greater-than-expected risk for evolving into malignant melanoma, the magnitude of that risk is uncertain. For this reason, the management of patients with these lesions remains controversial. The National Institutes of Health Consensus Conference guidelines are presented with specific recommendations for the management of patients
PMID: 3830488
ISSN: 0733-8635
CID: 16849
The dysplastic nevus. Clinical and pathologic features
Friedman RJ; Heilman ER; Rigel DS; Kopf AW
The dysplastic nevus has not only been considered to be a 'marker,' but also a formal 'precursor' of malignant melanoma. Therefore, these lesions are important to recognize clinically. This article presents a classification of the dysplastic nevus based upon its variable clinical presentations. It is hoped that this classification will assist the physician to recognize many of the clinical variants of this unusual melanocytic nevus and, thus, to identify patients at greater risk for the development of malignant melanoma
PMID: 3830487
ISSN: 0733-8635
CID: 16850
Congenital-nevus-like nevi, nevi spili, and cafe-au-lait spots in patients with malignant melanoma
Kopf AW; Levine LJ; Rigel DS; Friedman RJ; Levenstein M
The prevalence of congenital-nevus-like nevi (CNLN) in a group of 105 adults who had malignant melanoma (MM) was compared with that in a control group of 601 adults not afflicted by MM. Total cutaneous examinations were performed on both groups. The control group presented with complaints other than pigmented lesions. In this series, 10 (9.5%) of the group with MM had clinically diagnosed CNLN 1.5 cm or larger in diameter. These CNLN were not in contiguity with the MM sites. The 9.5% prevalence of CNLN in the group with MM was significantly higher (p less than 0.005) than the 2.5% CNLN observed in the control population. None of the patients in either group had large congenital nevocytic nevi (greater than or equal to 20 cm). In addition, in the group with MM, 5 patients (4.8%) had nevi spili (NS) and 13 (12.4%) had cafe-au-lait spots (CLS). The prevalence rates for these two types of pigmented lesions were not significantly different from those observed in the nonmelanoma control group (2.3% for NS; 13.8% for CLS). The relative risk for developing MM is 4.1 in people with CNLN compared with those without CNLN, which indicates that these nevi may be markers for individuals prone to develop malignant melanoma
PMID: 3973199
ISSN: 0148-0812
CID: 16851
Is it time for a computer in your practice? V. How to evaluate if a computer is appropriate for your practice
Rigel DS
In this article, a strategy for evaluating your practice in terms of its potential for computerization has been outlined. The rules that have been presented are general guidelines and exceptions may exist in any practice due to its specific needs. The use of a medical office computer consultant may help you to make this evaluation in a more effective manner. Once you have determined that your practice may benefit by the use of a computer, the next step is to select between the myriad of currently available systems. The next article in the series will be devoted to describing a method to help you select the system most appropriate for your setting
PMID: 3919072
ISSN: 0148-0812
CID: 16852
HAZARD-RATE ANALYSIS IN STAGE-I MELANOMA [Meeting Abstract]
Rogers, GS; Kopf, AW; Levenstein, M; Rigel, DS
ISI:A1985AQD5900220
ISSN: 0009-9279
CID: 30726
SYMPOSIUM ON MELANOMA AND PIGMENTED LESIONS - FOREWORD [Editorial]
Rigel, DS; Friedman, RJ
ISI:A1985AGH9600001
ISSN: 0733-8635
CID: 30913
Symposium on melanoma and pigmented lesions
Friedman, Robert J.; Rigel, Darrell S
Philadelphia : Saunders, 1985
Extent: x, p. 195-369 : ill. ; 27 cm
ISBN: n/a
CID: 41
PROGNOSIS IN MALIGNANT-MELANOMA [Meeting Abstract]
Rigel, DS
ISI:A1985ANQ5000047
ISSN: 0148-0812
CID: 30861
Surgical margins for removal of dysplastic nevi
Rigel DS; Friedman RJ; Kopf AW
ORIGINAL:0005560
ISSN: 0148-0812
CID: 62472
Malignant melanoma in World War II veterans
Brown J; Kopf AW; Rigel DS; Friedman RJ
In a consecutive series of 1,067 patients entered into the data base of the Melanoma Cooperative Group at New York University School of Medicine between 1972 and 1980, 120 men were of draft age (18-31 years) during World War II (1941-1945). Questionnaires were sent to these 120 individuals; 89 responded. Simultaneously, a control (nonmelanoma) population of 65 men of similar age was queried. Each subject in both groups was asked whether he had served in the armed forces during World War II and, if so, what were his theaters of operation. Based on the response, 83% (74 of 89) of the melanoma group compared with 76% (49 of 65) of the control group had served in the armed forces during World War II; however, a significantly (p = 0.0002) greater percent of the melanoma patients (34%) served in the tropics than did the control subjects (6%). Further, overrepresented in the melanoma group that served in the tropics (compared with the melanoma group who served in the armed forces in nontropical theaters) were malignant melanomas that had their origin in nevocytic nevi. The findings suggest that Caucasian individuals heavily exposed to sunlight in the tropics for several years during early life may be at higher risk to the subsequent development of cutaneous malignant melanoma. In some individuals this may be a two-step phenomenon, in which the first step is the solar induction of nevocytic nevi and the second is malignant transformation within them
PMID: 6526560
ISSN: 0011-9059
CID: 16853