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Opioids and designer drugs
Ford M; Hoffman RS; Goldfrank LR
Despite the increasing use of other illicit drugs, opioid abuse, overdose, and the ensuing medical complications continue to pose management challenges for the emergency physician. Heroin use is increasing as abusers of cocaine seek a drug to prolong cocaine's effects while blunting the postcocaine depression. Clandestine chemists have created newer, more powerful compounds--designer drugs--whose potencies are many-fold that of the presently available opioids. Aggressive airway support and use of naloxone enable the emergency physician to salvage many of these patients, leaving the many medical complications of parenteral and inhalational use as the greatest management challenge
PMID: 2201517
ISSN: 0733-8627
CID: 44395
The impact of drug abuse and addiction on society
Hoffman RS; Goldfrank LR
Over 28 million Americans have admitted to abusing a substance in the last year alone, at a direct purchase price of over 79 billion dollars. Substance abuse and addiction have grave consequences on our existing social systems, effecting crime rates, hospitalizations, child abuse, and child neglect, and are rapidly consuming limited public funds. The intravenous drug abuser represents the fastest growing vector of HIV virus. This report focuses on the social and economic implications of substance abuse and addiction and discusses the merits and limitations of several popular solutions to the problem
PMID: 2201515
ISSN: 0733-8627
CID: 44396
Prospective evaluation of "crack-vial" ingestions
Hoffman RS; Chiang WK; Weisman RS; Goldfrank LR
The 'crack' (cocaine alkaloid) epidemic has resulted in an increasing number of hospitalizations of 'crack-vial body-stuffers,' or patients who ingest 'crack-vials' in an attempt to avoid prosecution. Management strategies for this type of ingestion are lacking because of the paucity of data. This report discusses the demographics and symptomatology of 23 patients with 'crack-vial' ingestions, as well as the value of abdominal radiographs and the utility of varied strategies for decontamination in this patient population
PMID: 2327069
ISSN: 0145-6296
CID: 42090
BRETYLIUM TOSYLATE AND ELECTRICALLY INDUCED CARDIAC-ARRHYTHMIAS DURING HYPOTHERMIA IN DOGS [Meeting Abstract]
Orts, A; Alcaraz, C; Goldfrank, L; Delaney, K; Turndorf, H; Puig, MM
ISI:A1990CP98700277
ISSN: 0009-9236
CID: 32008
The medical complications of drug abuse
Chiang W; Goldfrank L
There is a vast array of abused drugs, and only a few of the more commonly used substances have been discussed. Patients with drug abuse frequently present with atypical syndromes and diseases. These individuals usually have less social, medical and economic support, making them more susceptible to the diseases that are associated with poverty, such as tuberculosis, and the complications of diseases such as hypertension, congestive heart disease and diabetes that require long-term care. Our strategy in the evaluation of these patients should consider all these aspects of medicine. A meticulous assessment and comprehensive care are necessary to render quality care for these complicated human and toxicological problems
PMID: 2404189
ISSN: 0025-729x
CID: 42093
Goldfrank's toxicologic emergencies
Flomenbaum, Neal E.; Lewin, Neal A.; Howland, Mary Ann.; Goldfrank, Lewis R
Norwalk, Conn. : Appleton & Lange, c1990
Extent: xxiii, 992 p. : ill. ; 29 cm
ISBN: n/a
CID: 258
Goldfrank's toxicologic emergencies
Goldfrank LR
Norwalk CT : Appleton & Lange, 1990
Extent: 992 p.
ISBN: 0838531433
CID: 795
Metabolic aspects of hyperthermia
Chapter by: Delaney KA; Goldfrank LR
in: The metabolic and molecular basis of acquired disease by Cohen RD [Eds]
London : Balliere Tindall, 1990
pp. 381-402
ISBN: 0702014931
CID: 3323
Buprenorphine decreases lethal effects of cocaine [Meeting Abstract]
Shukla VK; Goldfrank L; Turndorf H; Puig MM; Bansinath M
ORIGINAL:0004975
ISSN: 0031-7004
CID: 47308
Vital signs and toxic syndromes
Chapter by: Goldfrank L; Flomenbaum R; Lewin N
in: Goldfrank's toxicologic emergencies by Goldfrank, Lewis R [Eds]
Norwalk CT : Appleton & Lange, 1990
pp. 65-71
ISBN: 0838531431
CID: 4491