Faculty Bibliography

Mononeuropathy multiplex and mixed sensorimotor neuropathy are known complications of systemic vasculitis and related autoimmune disorders. Autonomic dysfunction is not generally considered a neurologic complication of these diseases. We report two patients who came to neurologic attention because of autonomic dysfunction and were then discovered to have autoimmune disease. Autonomic dysfunction may be the presenting sign of autoimmune disorders, which should be considered in the differential diagnosis of acquired autonomic disturbances

Cholangiocarcinoma is an uncommon tumor that presents with hepatobiliary dysfunction. We report a patient with a chronic progressive organic mental syndrome, diffuse weakness, and gait disturbance who was discovered to have obstructive hydrocephalus due to a neoplasm. Pathologic examination revealed primary cholangiocarcinoma metastatic to the cerebellum. This tumor has not been previously reported to present with neurologic involvement.