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Re: Prostate Cancer Detection with Magnetic Resonance-Ultrasound Fusion Biopsy: The Role of Systematic and Targeted Biopsies

Taneja, Samir S
PMID: 27321501
ISSN: 1527-3792
CID: 2263782

Re: Androgen Deprivation Therapy and Future Alzheimer's Disease Risk

Taneja, Samir S
PMID: 27321500
ISSN: 1527-3792
CID: 2263772

Re: Medium-Term Outcomes after Whole-Gland High-Intensity Focused Ultrasound for the Treatment of Nonmetastatic Prostate Cancer from a Multicentre Registry Cohort

Taneja, Samir S
PMID: 27321502
ISSN: 1527-3792
CID: 2263792

Application of anatomically accurate, patient-specific 3D printed models from MRI data in urological oncology

Wake, N; Chandarana, H; Huang, W C; Taneja, S S; Rosenkrantz, A B
PMID: 26983650
ISSN: 1365-229x
CID: 2032012

Re: Statin Use at the Time of Initiation of Androgen Deprivation Therapy and Time to Progression in Patients with Hormone-Sensitive Prostate Cancer

Taneja, Samir S
PMID: 27191069
ISSN: 1527-3792
CID: 2263722

Re: Nadir Testosterone within First Year of Androgen-Deprivation Therapy (ADT) Predicts for Time to Castration-Resistant Progression: A Secondary Analysis of the PR-7 Trial of Intermittent versus Continuous ADT

Taneja, Samir S
PMID: 27191068
ISSN: 1527-3792
CID: 2263712

Re: Nine-Year Follow-up for a Study of Diffusion-Weighted Magnetic Resonance Imaging in a Prospective Prostate Cancer Active Surveillance Cohort

Taneja, Samir S
PMID: 27191070
ISSN: 1527-3792
CID: 2263732

Re: Validation of an RNA Cell Cycle Progression Score for Predicting Death from Prostate Cancer in a Conservatively Managed Needle Biopsy Cohort

Taneja, Samir S
PMID: 27191067
ISSN: 1527-3792
CID: 2263702

Prostate Cancer Detection Using Computed Very High b-value Diffusion-weighted Imaging: How High Should We Go?

Rosenkrantz, Andrew B; Parikh, Nainesh; Kierans, Andrea S; Kong, Max Xiangtian; Babb, James S; Taneja, Samir S; Ream, Justin M
RATIONALE AND OBJECTIVES: The aim of this study was to assess prostate cancer detection using a broad range of computed b-values up to 5000 s/mm2. MATERIALS AND METHODS: This retrospective Health Insurance Portability and Accountability Act-compliant study was approved by an institutional review board with consent waiver. Forty-nine patients (63 +/- 8 years) underwent 3T prostate magnetic resonance imaging before prostatectomy. Examinations included diffusion-weighted imaging (DWI) with b-values of 50 and 1000 s/mm2. Seven computed DWI image sets (b-values: 1000, 1500, 2000, 2500, 3000, 4000, and 5000 s/mm2) were generated by mono-exponential fit. Two blinded radiologists (R1 [attending], R2 [fellow]) independently evaluated diffusion weighted image sets for image quality and dominant lesion location. A separate unblinded radiologist placed regions of interest to measure tumor-to-peripheral zone (PZ) contrast. Pathologic findings from prostatectomy served as reference standard. Measures were compared between b-values using the Jonckheere-Terpstra trend test, Spearman correlation coefficient, and generalized estimating equations based on logistic regression for correlated data. RESULTS: As b-value increased, tumor-to-PZ contrast and benign prostate suppression for both readers increased (r = +0.65 to +0.71, P 6 tumor was highest for R1 at b1500-3000 (90%-93%) and for R2 at 1500-2500 (78%-80%). The positive predictive value for tumor for R1 was similar from b1000 to 4000 (93%-98%) and for R2 was similar from b1500 to 4000 (88%-94%). CONCLUSIONS: Computed b-values in the range of 1500-2500 s/mm2 (but not higher) were optimal for prostate cancer detection; b-values of 1000 or 3000-5000 exhibited overall lower performance.
PMID: 26992738
ISSN: 1878-4046
CID: 2032222

Re: Long-Term Follow-up of a Randomized Trial of Radiation with or without Androgen Deprivation Therapy for Localized Prostate Cancer

Taneja, Samir S
PMID: 27186728
ISSN: 1527-3792
CID: 2263672