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Scar resurfacing with high-energy, short-pulsed and flashscanning carbon dioxide lasers [see comments] [Comment]

Bernstein LJ; Kauvar AN; Grossman MC; Geronemus RG
BACKGROUND: Scars have a significant effect on a person's physical and social being. Many treatment modalities for scar improvement such as surgical scar revision, electrosurgical planing, chemical peeling, filler substance implantation, and dermabrasion have been developed. Recently, the resurfacing carbon dioxide (CO2) laser systems have proven to be a useful and safe treatment in the treatment of facial rhytides and acne scarring. OBJECTIVE: The purpose of this study was to evaluate the resurfacing CO2 lasers in the treatment of various surgical, traumatic, acne, and varicella scars. METHODS: Thirty subjects, aging between 14 and 84 years, with surgical, traumatic, acne, or varicella scars were evaluated. Two types of resurfacing laser systems were utilized in this study, a high-energy, short-pulsed CO2 laser and a continuous wave CO2 laser with an optico-mechanical computer flash-scanner. Post-surgical scars were treated with laser resurfacing between 4 and 6 weeks after scar formation. Traumatic, acne, and varicella scars were treated after scar maturation (range, 1-10 years). Scar improvement was evaluated by photographic analysis of before and after images by four independent health care workers using a quartile scale of improvement (< 25%, 25-49%, 50-74%, > 75%) as well as optical profilometry using silicone surface impressions in 12 scars. RESULTS: Twenty of 24 surgical scars had greater than 75% improvement, and 24 of 24 had greater than 50% improvement by photographic analysis. All six traumatic, acne and varicella scars had greater than 50% improvement. Optical profilometry and surface topography maps reveal a significant flattening of related and depressed scars. CONCLUSION: The high-energy, short-pulsed CO2 laser and the continuous wave CO2 laser with flash-scanning attachment are safe and effective as a treatment modality for scar revision. In general, elevated scars improve more dramatically than depressed scars
PMID: 9464297
ISSN: 1076-0512
CID: 9152

Multimodal management of diffuse neonatal hemangiomatosis [Letter]

Blei F; Orlow SJ; Geronemus R
PMID: 9418785
ISSN: 0190-9622
CID: 57104

Guidelines of care for hemangiomas of infancy. American Academy of Dermatology Guidelines/Outcomes Committee [see comments] [Comment]

Frieden IJ; Eichenfield LF; Esterly NB; Geronemus R; Mallory SB
PMID: 9344205
ISSN: 0190-9622
CID: 9153

Effect of dynamic cooling on 585-nm pulsed dye laser treatment of port-wine stain birthmarks [see comments] [Comment]

Waldorf HA; Alster TS; McMillan K; Kauvar AN; Geronemus RG; Nelson JS
BACKGROUND AND OBJECTIVE: The objective of this study was to determine the effectiveness of a dynamic cooling device (DCD), spraying the skin with a brief spurt of cryogen prior to the laser pulse, in reducing transient pain associated with 585-nm pulsed dye laser (PDL) treatment of port-wine stains (PWS), and reducing epidermal damage (hypo/hyperpigmentation) caused by this laser during PWS treatment. MATERIALS AND METHODS: Matched treatment sites were compared with and without the use of the cryogen spray in 47 patients at two investigational sites. Pain ratings, clearance of the PWS, and pigmentation changes were assessed. The results were analyzed by skin type and patient age. RESULTS: A statistically significant reduction in pain ratings was found in all patient groups using the DCD without changing the efficacy of PWS clearance. Pain reduction was most remarkable in patients with darker skin types. Dynamic cooling prevented the occurrence of epidermal damage or pigmentation change in most cases. CONCLUSIONS: This study suggests that dynamic cooling can dramatically diminish pain during PWS treatment with the 585-nm PDL without reducing treatment efficacy. The absence of epidermal damage in most patients suggests that precooling with the DCD may allow the use of higher laser fluences to expedite clearance without inducing epidermal change. Dynamic cooling has potential use with other lasers and different lesions where discomfort and epidermal effects limit therapy
PMID: 9256912
ISSN: 1076-0512
CID: 9154

The short- and long-term side effects of carbon dioxide laser resurfacing [see comments] [Comment]

Bernstein LJ; Kauvar AN; Grossman MC; Geronemus RG
BACKGROUND: Carbon dioxide (CO2) laser resurfacing has become a very popular method of rhytide and scar removal in the recent past. Preliminary studies have been published describing the method, histology, and clinical results of CO2 laser resurfacing. However, none of these studies has dealt with long-term follow-up results. OBJECTIVE: To review all side effects resulting from CO2 laser resurfacing with regard to both short- and long-term effects. METHOD: Retrospective analysis of 104 patients who have undergone CO2 laser resurfacing for either facial rhytides and/or scarring with follow-up periods of 4-23 months (average, 8.2 months). RESULTS: The incidence of side effects are generally very low for CO2 laser resurfacing, including scarring, postinflammatory hyperpigmentation, and infection. However, there is a significant and previously unreported risk of hypopigmentation in an area of the population who often seek improvement in the appearance. CONCLUSIONS: CO2 laser resurfacing of facial rhytides and acne scars can be a very safe procedure by an experienced laser operator. However, careful patient selection, thorough patient instruction, and proper aesthetic analysis of treatment sites must be followed to insure the most favorable outcomes with CO2 laser resurfacing
PMID: 9236869
ISSN: 1076-0512
CID: 9155

Histology of laser resurfacing

Kauvar AN; Geronemus RG
The development of high-peak power or scanned CO2 lasers that precisely remove layers of photodamaged skin has provided a novel method of skin rejuvenation. Clinical data suggest that laser resurfacing provides comparable or better results than conventional methods of chemical peeling and mechanical dermabrasion, with a lower risk-to-benefit ratio. Histologic studies of the effects of these lasers on tissue have been helpful in establishing guidelines for appropriate clinical use of these lasers and insights into the mechanisms whereby facial skin rejuvenation is achieved
PMID: 9189682
ISSN: 0733-8635
CID: 9156

Keloid formation with the 585-nm pulsed dye laser during isotretinoin treatment [Letter]

Bernestein LJ; Geronemus RG
PMID: 9006390
ISSN: 0003-987x
CID: 9157

Tattoo formation from absorbable synthetic suture and successful removal with Q-switched ruby laser [see comments] [Comment]

Bernstein LJ; Palaia DA; Bank D; Geronemus RG
BACKGROUND: Traumatic tattoos result from accidental or unintentional deposition of exogenous pigment within injured skin. Pigments may consist of heavy metals, vegetable matter, or commercial dyes. OBJECTIVE: The clinical and histologic description of a traumatic tattoo resulting from a surgical procedure using undyed, braided, synthetic, absorbable suture material and its removal with the Q-switched ruby laser (694 nm, 28 nsec). METHODS: The pigmented linear lesion was biopsied and processed using standard histological methods. Subsequently, the area was treated on two occasions with the Q-switched ruby laser. RESULTS: The pigmented lesion was completely removed with the Q-switched laser treatments. CONCLUSION: We report on the occurrence of a traumatic tattoo resulting from synthetic suture material and complete removal with the Q-switched ruby laser
PMID: 9078317
ISSN: 1076-0512
CID: 9158

Histology of high-energy pulsed CO2 laser resurfacing

Alster TS; Kauvar AN; Geronemus RG
Cutaneous laser resurfacing is already proving to be a highly effective tool for improving photodamaged or scarred skin. The clinical and histological effects of the new high-energy, pulsed carbon dioxide (CO2) systems compare favorably with other treatments such as dermabrasion and chemical peels. The tissue-tightening effect noted after laser treatment may account for the claims of superior clinical improvement and needs further investigation
PMID: 8948537
ISSN: 1085-5629
CID: 9159

Surgical pearl: Q-switched Nd:YAG laser removal of eyeliner tattoo [Case Report]

Geronemus RG
PMID: 8682942
ISSN: 0190-9622
CID: 9160