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Wound complications after obstetric anal sphincter injuries
Lewicky-Gaupp, Christina; Leader-Cramer, Alix; Johnson, Lisa L; Kenton, Kimberly; Gossett, Dana R
OBJECTIVE:To estimate the incidence of and risk factors for wound complications in women who sustain obstetric anal sphincter injuries. METHODS:This was a prospective cohort study of women who sustained obstetric anal sphincter injuries during delivery of a full-term neonate between September 2011 and August 2013. Women were seen in the urogynecology clinic within 1 week of delivery and at 2, 6, and 12 weeks postpartum for perineal wound assessment. A visual analog scale for pain was administered at each visit. RESULTS:Five hundred two women met inclusion criteria for the study, and, ultimately, 268 women (54%) were enrolled. Eighty-seven percent of the cohort was nulliparous and 81% had a third-degree laceration. The majority (n=194) underwent an operative vaginal delivery (66.0% forceps and 6.0% vacuum). The overall risk was 19.8% (95% confidence interval [CI] 15.2-25.1%) for wound infection (n=53) and 24.6% (95% CI 19.6-30.2%) for wound breakdown (n=66). Operative vaginal delivery was associated with wound complications (infection, breakdown, or both) (adjusted odds ratio [OR] 2.54, 95% CI 1.32-4.87, P=.008). Intrapartum antibiotic therapy for obstetric indications was associated with a decreased risk of wound complications (adjusted OR 0.50, 95% CI 0.27-0.94, P=.03). Women with a wound complication reported significantly more pain within 1 week of delivery than women with a normally healing perineum (visual analog scale: 40.1±25.6 compared with 31.0±23, P=.002); this persisted at 12 weeks postpartum (6.6±7.5 compared with 3.4±7.1, P=.005). CONCLUSION/CONCLUSIONS:Women who sustain obstetric anal sphincter injuries are at high risk for the development of wound complications in the early postpartum period, warranting immediate and consistent follow-up. LEVEL OF EVIDENCE/METHODS:II.
PMID: 25932836
ISSN: 1873-233x
CID: 4418892
Risk of venous thromboembolism in abdominal versus minimally invasive hysterectomy for benign conditions
Barber, Emma L; Neubauer, Nikki L; Gossett, Dana R
OBJECTIVE:We sought to describe the incidence of venous thromboembolism (VTE) following hysterectomy for benign conditions and to estimate if VTE incidence differs for abdominal and minimally invasive hysterectomy. STUDY DESIGN/METHODS:Data for patients who underwent hysterectomy for benign conditions from 2010 through 2012 were abstracted from the American College of Surgeons National Surgical Quality Improvement Program database. Cases of VTE were compared to those without VTE. Minimally invasive hysterectomy was defined as both vaginal and laparoscopic hysterectomy. Pearson χ2 test, Student t test, and binary logistic regression were used for analysis. RESULTS:A total of 44,167 patients underwent hysterectomy; 12,733 (28.8%) underwent open hysterectomy, 22,559 (51.1%) underwent laparoscopic hysterectomy, and 8875 (20.1%) underwent vaginal hysterectomy. The incidence of VTE for open hysterectomy was higher (0.6%, 81/12,733) than minimally invasive hysterectomy (0.2% 73/31,434, P<.001). Open surgery (P<.001), body mass index (P=.006), race (P<.001), diabetes (P=.037), preoperative functional status (P<.001), American Society of Anesthesiologists class (P<.001), total operative time (P<.001), and time from surgery to discharge (P<.001) were each associated with VTE. Age, hypertension, current smoking, pack-year history, and year operation was performed were not associated with VTE. Using binary logistic regression, open surgery (P<.001), operative time (P<.001), and length of stay (P<.001) remained associated with VTE. The odds ratio for VTE after open hysterectomy compared with minimally invasive hysterectomy was 2.45 (95% confidence interval, 1.77-3.40). CONCLUSION/CONCLUSIONS:In this large quality database, a minimally invasive approach to hysterectomy was independently associated with a decreased incidence of VTE when compared with open hysterectomy.
PMID: 25511239
ISSN: 1097-6868
CID: 4418882
Postpartum Contraceptive Choice Among Patients After High-Risk Pregnancy [Meeting Abstract]
French, Maureen; Albanese, Alexandra; Gossett, Dana R.
ISI:000354128700206
ISSN: 0029-7844
CID: 4419182
Management of Menstrual Bleeding During Treatment for Nongynecologic Malignancy [Meeting Abstract]
Johnson, Kiila Nicole; Bortoletto, Pietro; Gossett, Dana R.
ISI:000354128700111
ISSN: 0029-7844
CID: 4419172
Request and Fulfillment of Postpartum Tubal Ligation in Patients After High-Risk Pregnancy [Meeting Abstract]
Albanese, Alexandra; French, Maureen; Gossett, Dana R.
ISI:000354128700242
ISSN: 0029-7844
CID: 4419192
Development and evaluation of cesarean section surgical training using computer-enhanced visual learning
York, Sloane L; Maizels, Max; Cohen, Elaine; Stoltz, Rachel Stork; Jamil, Adeel; McGaghie, William C; Gossett, Dana R
BACKGROUND:Skilled performance of cesarean deliveries is essential in obstetrics and gynecology residency. A computer-enhanced visual learning module (CEVL Cesarean) was developed to teach cesarean deliveries. METHODS:An online module presented cesarean deliveries as a series of components using text, audio, video and animation. First-year residents used CEVL Cesarean and were evaluated intra-operatively by trained raters, then provided feedback about surgical performance. Clinical outcomes were collected for approximately 50 cesarean deliveries for each resident. RESULTS:From 2010 to 2011, 12 first-year residents participated in the study. About 406 unique observed cesarean deliveries were analyzed. Procedures up to each resident's 70th case were analyzed by grouping cases in 10 s (cases 1-10 and 11-20), or deciles. Resident performance significantly improved by decile [χ(2)(6) = 47.56, p < 0.001]. When examining each resident's performance, surgical skill acquisition plateaued by cases 21-30. Procedural performance, independent of resident, also improved significantly by decile [χ(2)(6) = 186.95, p < 0.001], plateauing by decile 4 (cases 31-40). Throughout the observation period, operative time decreased by 3.84 min (p = 0.006). CONCLUSIONS:Pre-clinical teaching using computer-based modules for cesarean sections is feasible to develop. Novice surgeons required at least 30 procedures before performing the procedure competently. When residents performed competently, operative time and complications decreased.
PMID: 25072410
ISSN: 1466-187x
CID: 4418862
Association between obstetrician forceps volume and maternal and neonatal outcomes
Miller, Emily S; Barber, Emma L; McDonald, Katherine D; Gossett, Dana R
OBJECTIVE:To estimate the association between obstetric forceps volume and severe perineal lacerations or adverse neonatal outcomes. METHODS:This is a retrospective cohort of forceps deliveries performed at a tertiary care hospital. Obstetricians were grouped by quartile of forceps volume over the study time period. Severe (third- or fourth-degree) perineal lacerations and adverse neonatal outcomes were compared across quartiles. Individual patient characteristics were controlled for using multilevel multivariable analysis. This study had 90% power to detect a twofold difference in severe perineal lacerations between the first and fourth quartiles. Additional analyses were performed using physician years in practice or year of residency of the involved resident physicians. RESULTS:One hundred eighteen attending physicians (2,369 forceps deliveries) were included. The median (interquartile range) annual number of forceps per quartile was 1.3 (1.0-1.8), 3.8 (3.0-4.3), 6.3 (5.5-6.8), and 11.5 (9.8-17.3). The frequency of severe perineal lacerations from lowest to highest quartile was 29.9%, 27.5%, 33.3%, and 36.9% (P=.013). After adjusting for confounders, the relationship between volume quartile and severe perineal lacerations became nonsignificant. Although not powered to this outcome, the frequency of composite adverse neonatal outcome was not associated with volume quartile in either bivariate or multivariable analysis. Similarly, neither physician years of practice nor resident year was associated with severe perineal laceration. However, more experience as a resident was associated with a reduced odds of composite adverse neonatal outcomes. CONCLUSIONS:After controlling for patient factors, neither attending forceps volume nor physician years in practice was associated with severe perineal lacerations or composite neonatal injury. LEVEL OF EVIDENCE/METHODS:II.
PMID: 24402600
ISSN: 1873-233x
CID: 4418852
Subsequent Pregnancy Outcomes After Obstetric Anal Sphincter Injuries (OASIS) [Editorial]
Basham, Elizabeth; Stock, Laura; Lewicky-Gaupp, Christina; Mitchell, Christopher; Gossett, Dana R.
ISI:000331541900009
ISSN: 0029-7828
CID: 4419142
Subsequent pregnancy outcomes after obstetric anal sphincter injuries (OASIS)
Basham, Elizabeth; Stock, Laura; Lewicky-Gaupp, Christina; Mitchell, Christopher; Gossett, Dana R
OBJECTIVES/OBJECTIVE:To describe obstetric outcomes in women with a prior obstetric anal sphincter injury (OASIS) and to identify risk factors for recurrence. METHODS:A retrospective chart review of women who sustained an OASIS between November 2005 and March 2010 at a tertiary care hospital was performed to identify risk factors for recurrence. RESULTS:One thousand six hundred twenty-nine patients had an OASIS. Of these, 758 patients (90%) subsequently delivered during the aforementioned timeframe; 685 patients had a subsequent vaginal delivery. Of the women, 3.2% had a recurrent OASIS. Recurrence was associated with larger birth weight (27% ≥4000 g vs 11.6% <4000 g; P = 0.04) and delivery mode (25.0%, 12.5%, and 2.7% for forceps-assisted, vacuum-assisted, and spontaneous deliveries, respectively (P = 0.0001)), whereas a history of fourth-degree laceration, prior wound complication, or episiotomy at subsequent delivery were not (P = 0.5, P = 0.5, and P = 0.4, respectively). CONCLUSIONS:Recurrent OASIS occurred in a small percentage of women (3.2%) who subsequently delivered vaginally. Recurrent OASIS was associated with operative vaginal delivery and birth weight 4000 g or greater. Neither episiotomy at first delivery nor at subsequent delivery conferred an increased recurrence risk.
PMID: 24165445
ISSN: 2151-8378
CID: 4418842
Controversy over contraception coverage--reply [Comment]
Gossett, Dana R; Kiley, Jessica; Hammond, Cassing
PMID: 24065021
ISSN: 1538-3598
CID: 4418822