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BMI Trajectory and Attributable Risk of New Onset Hypertension Among Obese Living Kidney Donors. [Meeting Abstract]

Reed, R. D.; McLeod, M. C.; MacLennan, P. A.; Kumar, V.; Brooks, S. E.; Maynor, A. G.; Stanford, L. A.; Baker, G. A.; Schinstock, C. A.; Silkensen, J. R.; Roll, G. R.; Segev, D. L.; Orandi, B. J.; Lewis, C. E.; Locke, J. E.
ISI:000842606302100
ISSN: 1600-6135
CID: 5521272

Evaluation of Diabetes-Free Life Expectancy Among Living Kidney Donors and Non-Donors with Obesity: A Longitudinal Cohort Study. [Meeting Abstract]

Killian, C.; Reed, R.; McLeod, M.; MacLennan, P.; Kumar, V.; Brooks, S.; Maynor, A.; Stanford, L.; Baker, G.; Schinstock, C.; Silkensen, J.; Roll, G.; Segev, D.; Orandi, B.; Lewis, C.; Locke, J.
ISI:000842606302099
ISSN: 1600-6135
CID: 5521262

Designing Continuous Distribution for Liver Allocation. [Meeting Abstract]

Mankowski, M.; Wood, N.; Segev, D.; Gentry, S.
ISI:000842606302312
ISSN: 1600-6135
CID: 5486642

SARS-coV-2 Antibody Response to a Third Dose of Homologous mRNA Vaccination in Liver Transplant Recipients [Meeting Abstract]

Chang, Amy; Strauss, Alexandra T.; Alejo, Jennifer L.; Chiang, Teresa Py; Hernandez, Nicole F.; Zeiser, Laura B.; Boyarsky, Brian J.; Avery, Robin K.; Tobian, Aaron Ar; Levan, Macey L.; Warren, Daniel S.; Massie, Allan B.; Garonzik-Wang, Jacqueline M.; Segev, Dorry L.; Werbel, William A.
ISI:000889117000393
ISSN: 0041-1337
CID: 5480722

Response to a Pandemic: The Fall and Rise of Kidney Transplantation in the United States [Meeting Abstract]

Bisen, Shivani; Boyarsky, Brian; Werbel, William; Snyder, Jon; Zeiser, Laura B.; Garonzik-Wang, Jacqueline; Levan, Macey L.; Segev, Dorry L.; Massie, Allan B.
ISI:000889117000331
ISSN: 0041-1337
CID: 5480712

Prediction of ESRD Risk in Living Kidney Donors Through Thirty Years Postdonation [Meeting Abstract]

Massie, Allan; Bendersky, Victoria A.; Snyder, Jon J.; Levan, Macey L.; Al-Ammary, Fawaz; Brennan, Daniel C.; Segev, Dorry L.
ISI:000889117000219
ISSN: 0041-1337
CID: 5480702

Ad.26.COV2.S Versus BNT162b2 or mRNA-1273 as a Third Dose in Solid Organ Transplant Recipients Seronegative After 2-dose mRNA Vaccination [Meeting Abstract]

Chiang, Teresa Po-Yu; Alejo, Jennifer L.; Mitchell, Jonathan; Kim, Jake D.; Abedon, Aura T.; Karaba, Andrew H.; Thomas, Letitia; Levan, Macey L.; Garonzik-Wang, Jacqueline M.; Avery, Robin K.; Pekosz, Andrew; Clarke, William A.; Warren, Daniel S.; Tobian, Aaron A. R.; Massie, Allan B.; Segev, Dorry L.; Werbel, William A.
ISI:000889117000108
ISSN: 0041-1337
CID: 5480682

Antibody Response to a Third Dose of SARS-CoV-2 Vaccine in Heart and Lung Transplant Recipients [Meeting Abstract]

Alejo, Jennifer; Ruck, Jessica M.; Chiang, Teresa P. Y.; Massie, Allan B.; Abedon, Aura T.; Tobian, Aaron A. R.; Levan, Macey L.; Warren, Daniel S.; Garonzik-Wang, Jacqueline M.; Segev, Dorry L.; Werbel, William A.
ISI:000889117000105
ISSN: 0041-1337
CID: 5480672

A CONTENT ANALYSIS OF VIDEO-BASED EDUCATIONAL MATERIALS FOR LIVER TRANSPLANT PATIENTS THROUGH THE LENSES OF BOTH PEDAGOGY AND HEALTH EQUITY [Meeting Abstract]

Rajpal, Neha; Hamilton, James P.; Levan, Macey L.; Segev, Dorry L.; Strauss, Alexandra T.
ISI:000870796603205
ISSN: 0270-9139
CID: 5480652

Diabetes-free survival among living kidney donors and non-donors with obesity: A longitudinal cohort study

Killian, A Cozette; Reed, Rhiannon D; McLeod, M Chandler; MacLennan, Paul A; Kumar, Vineeta; Pittman, Sydney E; Maynor, Andrew G; Stanford, Luke A; Baker, Gavin A; Schinstock, Carrie A; Silkensen, John R; Roll, Garrett R; Segev, Dorry L; Orandi, Babak J; Lewis, Cora E; Locke, Jayme E
BACKGROUND:Approval of living kidney donors (LKD) with end-stage kidney disease (ESKD) risk factors, such as obesity, has increased. While lifetime ESKD development data are lacking, the study of intermediate outcomes such as diabetes is critical for LKD safety. Donation-attributable diabetes risk among persons with obesity remains unknown. The purpose of this study was to evaluate 10-year diabetes-free survival among LKDs and non-donors with obesity. METHODS:This longitudinal cohort study identified adult, LKDs (1976-2020) from 42 US transplant centers and non-donors from the Coronary Artery Risk Development in Young Adults (1985-1986) and the Atherosclerosis Risk in Communities (1987-1989) studies with body mass index ≥30 kg/m2. LKDs were matched to non-donors on baseline characteristics (age, sex, race, body mass index, systolic and diastolic blood pressure) plus diabetes-specific risk factors (family history of diabetes, impaired fasting glucose, smoking history). Accelerated failure time models were utilized to evaluate 10-year diabetes-free survival. FINDINGS:Among 3464 participants, 1119 (32%) were LKDs and 2345 (68%) were non-donors. After matching on baseline characteristics plus diabetes-specific risk factors, 4% (7/165) LKDs and 9% (15/165) non-donors developed diabetes (median follow-up time 8.5 (IQR: 5.6-10.0) and 9.1 (IQR: 5.9-10.0) years, respectively). While not significant, LKDs were estimated to live diabetes-free 2 times longer than non-donors (estimate 1.91; 95% CI: 0.79-4.64, p = 0.15). CONCLUSIONS:LKDs with obesity trended toward living longer diabetes-free than non-donors with obesity, suggesting within the decade following donation there was no increased diabetes risk among LKDs. Further work is needed to evaluate donation-attributable diabetes risk long-term.
PMCID:9674148
PMID: 36399462
ISSN: 1932-6203
CID: 5371742