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Does transrenal fixation of aortic endografts impair renal function?

Cayne, Neal S; Rhee, Soo J; Veith, Frank J; Lipsitz, Evan C; Ohki, Takao; Gargiulo, Nicholas J 3rd; Mehta, Manish; Suggs, William D; Wain, Reese A; Rosenblit, Alla; Timaran, Carlos
OBJECTIVES: Transrenal fixation (TFX) of aortic endografts is thought to increase the risk for renal infarction and impaired renal function. We studied the late effects of TFX on renal function and perfusion. METHODS: Of 189 patients with commercial aortic endografts, which we inserted between 1995 and 2002, we reviewed data for 130 patients (112 men, 18 women) with available creatinine (Cr) concentration and contrast enhanced computed tomography (CT) scans preoperatively and 1 to 97 months after the procedure. Of the 130 patients, 69 patients had TFX and 61 patients had infrarenal fixation (IFX). Both groups were physiologically comparable. Average age was 76 +/- 8 years for patients with TFX and 75 +/- 8 years for patients with IFX. Presence of renal infarct or renal artery occlusion was determined by nephrograms on serial contrast-enhanced CT scans. RESULTS: Mean follow-up was 17 +/- 16 months (range, 1-54 months) for TFX and 21 +/- 21 months (range, 1-97 months) for IFX. Mean serum Cr concentration increased significantly during long-term follow-up in both groups (TFX, 1.3 +/- 0.5 mg/dL to 1.5 +/- 0.8 mg/dL, P <.01; IFX, 1.3 +/- 0.7 mg/dL to 1.4 +/- 0.8 mg/dL, P <.03). Creatinine clearance (CrCl) similarly decreased over long-term follow-up in both groups (TFX, 53.3 +/- 17.7 mL/min/1.73 m(2) to 47.9 +/- 16.2 mL/min/1.73 m(2), P <.01; IFX, 58.1 +/- 22.7 mL/min/1.73 m(2) to 53.1 +/- 23.4 mL/min/1.73 m(2), P <.02). There were no significant differences in the increase in Cr concentration (P =.19) or decrease in CrCl (P =.68) between TFX and IFX groups. Small renal infarcts were noted in four patients (5.8%) in the TFX group and one patient (1.6%) in the IFX group. No increase in Cr concentration or decrease in CrCl was noted in any patient with a renal infarct. Postoperative renal dysfunction developed in 7 of 69 patients (10.1%) in the TFX group and 7 of 61 patients (11.5%) in the IFX group. There were no statistically significant differences between groups with respect to number of patients with new renal infarcts (P =.37) or postoperative renal dysfunction (P =.81). CONCLUSION: There is a slight increase in serum Cr concentration and decrease in CrCl after aortic endografting. However, there was no significant difference in these changes between patients with TFX and IFX. Although TFX may produce a higher incidence of small renal infarcts, these do not impair renal function. Thus our midterm results suggest that TFX can be performed safely, with no greater change in renal function than observed after IFX
PMID: 14560206
ISSN: 0741-5214
CID: 38326

Endovascular repair of a traumatic pseudoaneurysm of the thoracic aorta in a patient with concomitant intracranial and intra-abdominal injuries [Case Report]

Zager, Jonathan S; Ohki, Takao; Simon, Jason E; Gruber, Brian; Zoe, Holly; Teperman, Sheldon H; Stone, Melvin E Jr; Veith, Frank J; Simon, Ronald J
PMID: 14566138
ISSN: 0022-5282
CID: 89479

Use of abdominal aortic endovascular prostheses in France from 1999 to 2001 - Invited commentary [Comment]

Veith, FJ
ISI:000186955400031
ISSN: 0741-5214
CID: 80083

Technical adjuncts to facilitate endovascular repair of various thoracic pathology

Ohki, Takao; Veith, Frank J
PMID: 12869183
ISSN: 0886-0440
CID: 79536

Regarding "Hemodynamic benefits of regional anesthesia for carotid endarterectomy" [Letter]

Mehta, Manish; Veith, Frank J
PMID: 12756368
ISSN: 0741-5214
CID: 79537

Vascular surgery won a battle but is losing the war: a call to arms for every vascular surgeon [Editorial]

Veith, Frank J
This paper describes the present status of the initiative to obtain American Board of Medical Specialties (ABMS) approval of an independent American Board of Vascular Surgery (ABVS). The need for such a board arises from the evolution of vascular surgery into a distinct, well-defined specialty that deals with all aspects of vascular disease, including knowledge of its natural history, all methods of noninvasive and invasive diagnosis, conservative and medical treatment, open operative treatment, endovascular treatment, and periprocedural care. Because of the greater skill requirements and increased complexity of vascular surgery, its paradigms of training must be changed. Longer periods of vascular training are required with a reciprocal 2- to 3-year shortening of training in general surgery. This cannot be done without an independent ABVS. The effort to obtain ABVS approval has elicited opposition from the American Board of Surgery (ABS) and from some vascular surgery leaders associated with it, making the ABVS a contentious issue. A successful effort was made to reach consensus within vascular surgery, and the ABVS application was submitted to the ABMS. As a result of an ABS campaign that combined pressure and dire warnings, this application encountered intense opposition within the ABMS and its Liaison Committee for Specialty Boards (LCSB). Institutional and professional self-interest, rather than quality of patient care, appeared to be the overriding considerations in the ABS argument. Measures to overcome this ABS opposition and obstructionism are proposed. They require unity, action, and tangible support from all vascular surgeons. If this call to arms goes unheeded, vascular surgery will not continue to be the self-sufficient specialty it has become and, most importantly, patient care will suffer
PMID: 12712373
ISSN: 0890-5096
CID: 79538

Current status of management of type II endoleaks after endovascular repair of abdominal aortic aneurysms

Rhee, Soo J; Ohki, Takao; Veith, Frank J; Kurvers, Harrie
PMID: 12712372
ISSN: 0890-5096
CID: 79539

Detection of endoleaks after endovascular repair of abdominal aortic aneurysm: value of unenhanced and delayed helical CT acquisitions

Rozenblit, Alla M; Patlas, Michael; Rosenbaum, Ayala T; Okhi, Takao; Veith, Frank J; Laks, Mitchell P; Ricci, Zina J
PURPOSE: To assess unenhanced and delayed phase computed tomographic (CT) images combined with arterial phase images for detecting endoleaks after endovascular treatment for abdominal aortic aneurysm (AAA). MATERIALS AND METHODS: CT scans were retrospectively evaluated for the presence of endoleaks after endovascular treatment of AAAs in 33 patients with endoleak (positive group) and 40 patients without evidence of endoleak or aneurysm enlargement (negative group). All patients underwent unenhanced and biphasic contrast material-enhanced CT. The CT scans were reviewed in the following combinations: (a) arterial phase and unenhanced scans (uniphasic/unenhanced set), (b) arterial and delayed phase scans only (biphasic set), and (c) arterial and delayed phase scans with unenhanced scans (complete set). Each set was reviewed by two radiologists blinded to the diagnosis of endoleak. Findings were recorded as positive, negative, or indeterminate for endoleak. RESULTS: Within the positive group, endoleaks were diagnosed with the uniphasic/unenhanced, biphasic, and complete image sets in 30 (91%), 32 (97%), and 33 (100%) patients, respectively. With the uniphasic/unenhanced set, three (9%) endoleaks (seen only on delayed phase images) were missed. With the biphasic set, one (3%) endoleak was interpreted as indeterminate. Within the negative group, uniphasic/unenhanced, biphasic, and complete image sets were negative for endoleaks in 100%, 80%, and 100% of patients, respectively. With the biphasic set, results were indeterminate in 20% of cases. CONCLUSION: A delayed CT acquisition enables detection of additional endoleaks, while an unenhanced acquisition helps eliminate indeterminate results. Thus, both acquisitions contribute to accurate diagnosis of endoleaks when combined with an arterial phase acquisition
PMID: 12676973
ISSN: 0033-8419
CID: 79540

Five-year results of a merger between vascular surgeons and interventional radiologists in a university medical center - Discussion [Editorial]

Akbari, C; Green, RM; Pappas, PJ; Veith, FJ; Sicard, GA; Shah, DM; Ricotta, JJ
ISI:000186955400020
ISSN: 0741-5214
CID: 80081

Endovascular treatment of ruptured infrarenal aortic and iliac aneurysms

Veith, F J; Gargiulo, N J 3rd; Ohki, T
PMID: 14743558
ISSN: 0001-5458
CID: 79636