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367


Effect of the topical anesthetic EMLA on the efficacy of pulsed dye laser treatment of port-wine stains

Ashinoff R; Geronemus RG
EMLA cream (Eutectic Mixture of Local Anesthetics) is a new topical anesthetic composed of 25 mg lidocaine and 25 mg prilocaine in an oil-in-water emulsion cream. It has been found to be very effective for local anesthesia prior to venepuncture, minor surgical procedures, and pulsed dye laser (PDL) therapy for port-wine stains (PWS) in children. However, since EMLA may cause vasoconstriction of cutaneous vessels, we tried to determine whether pretreatment with EMLA decreases the efficacy of subsequent PDL treatment. We report eight patients between the ages of 4 and 32 years with PWS who received two test site treatments prior to PDL treatment. One site was pretreated with EMLA cream under occlusion for 60 minutes and then left unoccluded for 15 minutes prior to PDL test treatment. The other site, in the same area of the PWS and patient's body, was not pretreated with EMLA. The test sites were compared 6-8 weeks later to determine whether EMLA decreased the degree of lightening of the PWS compared to the non-EMLA-treated site. We conclude that EMLA is an effective topical anesthetic for PDL treatment of PWS and does not adversely affect the efficacy of the treatment
PMID: 2246405
ISSN: 0148-0812
CID: 9200

Thrombocytopenia-absent radii syndrome and lack of response to the pulsed dye laser [Letter]

Ashinoff R; Geronemus RG
PMID: 2241212
ISSN: 0003-987x
CID: 9201

Presuturing in alopecia reductions

Meirson D; Reyes BA; Geronemus R
The technique of presuturing for alopecia reductions is described. With this procedure, the area of potential reduction is sutured 12-24 hours prior to surgery to enhance the laxity of the scalp
PMID: 2204646
ISSN: 0148-0812
CID: 9202

Poikiloderma of civatte [Letter]

Geronemus R
PMID: 2322008
ISSN: 0003-987x
CID: 9203

Dermatologic laser surgery

Garden JM; Geronemus RG
The laser is becoming an increasingly important surgical and medical instrument in the field of dermatology. Developments in the areas of laser technology and application have significantly broadened its clinical use over the past several years. These rapid changes and advances in the use of the laser for cutaneous processes may make it difficult for the physician to maintain a current base of knowledge in this area. Relevant laser systems and their clinical applications are presented and discussed, as are investigational laser systems, which may be of importance for the future. This will allow the dermatologic surgeon the opportunity to update concepts and evaluate the various laser systems and their cutaneous applications
PMID: 2105986
ISSN: 0148-0812
CID: 9204

Microcystic adnexal carcinoma of the scalp [Case Report]

Chow WC; Cockerell CJ; Geronemus RG
Microcystic adnexal carcinoma (MAC) is a recently described rare adnexal neoplasm showing benign histologic features but a locally aggressive behavior. It has most commonly been reported to occur on the face but it has also been noted in the axilla and buttock. We describe a 41-year-old white male with a 5-year history of MAC on the scalp and treatment by Mohs micrographic surgery. To our knowledge, this is the first case of MAC reported to occur on the scalp
PMID: 2473103
ISSN: 0148-0812
CID: 9205

The treatment of Zoon's balanitis with the carbon dioxide laser [Case Report]

Baldwin HE; Geronemus RG
Zoon's balanitis, or plasma cell balanitis, is a chronic erosive process of the uncircumcised penis. The lesions are often refractory to conservative topical and surgical therapy and frequently require circumcision as a curative measure. This case report describes the first reported successful use of the carbon dioxide laser in the defocused mode to vaporize the chronic penile erosions of Zoon's balanitis
PMID: 2497162
ISSN: 0148-0812
CID: 9206

The association of lichen planus of the penis with squamous cell carcinoma in situ and with verrucous squamous carcinoma [Case Report]

Bain L; Geronemus R
Two cases of squamous cell carcinoma (SCC) of the penis, one verrucous type and one in situ, arising in association with an inflammatory dermatosis most consistent with lichen planus, are described. Although SCC has previously been reported to have arisen from lichen planus of the oral mucosa, these are the first reported cases of the coexistence of these processes on the penis
PMID: 2925986
ISSN: 0148-0812
CID: 9207

Continuous arteriovenous hemofiltration for acute renal failure

Bartlett RH; Bosch J; Geronemus R; Paganini E; Ronco C; Swartz R
PMID: 3288257
ISSN: 0889-7190
CID: 9208

Ultraviolet laser ablation of skin: healing studies and a thermal model

Lane RJ; Wynne JJ; Geronemus RG
We have followed the course of healing of incisions made with the krypton-fluoride excimer laser. Incisions were made in guinea pig skin, in vivo, under identical conditions of irradiation. The progressive healing of these incisions was followed over the course of 3 weeks. We noted excellent healing with re-epithelialization, and the re-formation of collagen fibers with minimal fibrosis. We present a simple thermal model for ablation of tissue by a short pulse of strongly absorbed laser radiation.
PMID: 3573922
ISSN: 0196-8092
CID: 9209