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person:loebs01
Baseline prostate-specific antigen testing at a young age
Loeb, Stacy; Carter, H Ballentine; Catalona, William J; Moul, Judd W; Schroder, Fritz H
CONTEXT: Prostate cancer screening is highly controversial, including the age to begin prostate-specific antigen (PSA) testing. Several studies have evaluated the usefulness of baseline PSA measurements at a young age. OBJECTIVE: Review the literature on baseline PSA testing at a young age (=60 yr) for the prediction of prostate cancer risk and prognosis. EVIDENCE ACQUISITION: PubMed was searched for English-language publications on baseline PSA and prostate cancer for the period ending April 2011. EVIDENCE SYNTHESIS: In most published series, median PSA levels in the general male population range from approximately 0.4 to 0.7 ng/ml in men in their 40s and from approximately 0.7 to 1.0 ng/ml in men in their 50s. Evidence from both nonscreening and screening populations has demonstrated the predictive value of a single baseline PSA measurement for prostate cancer risk assessment. Specifically, men with baseline PSA levels above the age-group-specific median have a greater risk of prostate cancer diagnosis during the next 20-25 yr. Additional studies confirmed that higher baseline PSA levels at a young age are also associated with a greater risk of aggressive disease, metastasis, and disease-specific mortality many years later. CONCLUSIONS: Baseline PSA measurements at a young age are significant predictors of later prostate cancer diagnosis and disease-specific outcomes. Thus baseline PSA testing may be used for risk stratification and to guide screening protocols.
PMID: 21862205
ISSN: 0302-2838
CID: 160282
Prostate-specific antigen (PSA) should drive doing prostate biopsies
Loeb, Stacy; Catalona, William J
PMID: 21458316
ISSN: 1078-1439
CID: 160283
Reply from Authors re: Seth A. Strope, Gerald L. Andriole. Prostate-Specific Antigen-Based Risk Assessment in Younger Men. Eur Urol 2012;61:8-9 [Editorial]
Loeb, S; Carter, H B; Catalona, W J; Moul, J; Schroder, F H
EMBASE:51669061
ISSN: 1873-7560
CID: 3932432
Early detection, diagnosis, and staging of prostate cancer
Chapter by: Loeb, S; Carter, HB
in: Campbell-Walsh urology by Wein, Alan J [Eds]
Philadelphia, PA : Elsevier Saunders, c2012
pp. ?-?
ISBN: 9789996059186
CID: 160554
Radical retropubic prostatectomy: comparison of the open and robotic approaches for treatment of prostate cancer
Tosoian, Jeffrey J; Loeb, Stacy
Radical prostatectomy represents the standard of care for surgical treatment of clinically localized prostate cancer. First described in 1904, the operation became widely performed only after advances in diagnostic and surgical techniques occurred later in the century. Over time, open retropubic radical prostatectomy (RRP) became the most common operation for prostate cancer, and excellent long-term survival outcomes have been reported. More recently, minimally invasive techniques such as the robotic-assisted laparoscopic radical prostatectomy (RALRP) were introduced. Despite a lack of prospectively collected, long-term data supporting its use, RALRP has overtaken RRP as the most frequently performed prostate cancer operation in the United States. This article uses currently available data to compare oncologic, functional, and quality-of-life outcomes associated with both the open and robotic approaches to radical prostatectomy.
PMCID:3502048
PMID: 23172996
ISSN: 1523-6161
CID: 250492
Innovation in Endourology and Minimally Invasive Surgery: Highlights From the 29th World Congress of Endourology and SWL 2011, November 30-December 3, 2011, Kyoto, Japan
Loeb, Stacy; Borin, James F
PMCID:3502049
PMID: 23172997
ISSN: 1523-6161
CID: 250482
Prostate cancer screening and surgical management of localized disease: highlights from the 27th annual congress of the European association of urology, february 24-28, 2012, paris, france
Loeb, Stacy
PMCID:3602731
PMID: 23526727
ISSN: 1523-6161
CID: 250412
Best of the 2012 AUA Annual Meeting: Highlights From the 2012 American Urological Association Meeting, May 19-23, 2012, Atlanta, GA
Nickel, J Curtis; Partin, Alan W; Nirmal, Jayabalan; Chancellor, Michael B; Loeb, Stacy; Brawer, Michael K; Assimos, Dean; Shapiro, Ellen
PMCID:3602732
PMID: 23526762
ISSN: 1523-6161
CID: 250402
Utility of single nucleotide polymorphisms in prostate biopsy decisions
Loeb, Stacy; Braithwaite, R Scott; Hayes, Richard B
PMCID:3602735
PMID: 23526876
ISSN: 1523-6161
CID: 250392
Re: randomised prostate cancer screening trial: 20 year follow-up [Comment]
Loeb, Stacy; Trock, Bruce J
PMID: 22054407
ISSN: 0302-2838
CID: 160285