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Optical coherence tomography of bleb-like subretinal lesions after retinal reattachment surgery [Case Report]
Kaga, T; Fonseca, R A; Dantas, M A; Yannuzzi, L A; Spaide, R F
PURPOSE: To report the optical coherence tomographic characteristics of persistent bleb-like subretinal lesions after retinal reattachment surgery, including scleral buckling and cryopexy. METHODS: Case reports. RESULTS: In two eyes of two patients yellow to yellowish-orange bleb-like lesions were found in the posterior pole after retinal reattachment surgery. The common aspects of the surgery were scleral buckling procedures and cryopexy. There were subretinal precipitates in some of the lesions. The lesions showed no associated leakage during fluorescein or indocyanine green angiography. Optical coherence tomography demonstrated that the bleb-like lesions were tiny retinal detachments. CONCLUSION: Optical coherence tomography examination of bleb-like subretinal lesions showed that they were actually retinal detachments. Our patients and previously reported patients developed these lesions after scleral buckling and cryopexy. These lesions may represent persistent retinal detachment because of the presence of protein in the subretinal fluid
PMID: 11438071
ISSN: 0002-9394
CID: 103451
Polypoidal choroidal vasculopathy and central serous chorioretinopathy - Reply [Letter]
Yannuzzi, LA
ISI:000169027100014
ISSN: 0161-6420
CID: 103715
Retinal thickness and visual prognosis in central serous chorioretinopathy [Meeting Abstract]
Iida, T; Carvalho, C; Spaide, RF; Yannuzzi, LA
ISI:000168392103650
ISSN: 0146-0404
CID: 103642
Yellowish subretinal deposits in a leopard-spot pattern in central serous chorioretinopathy [Meeting Abstract]
Miller, AI; Iida, T; Spaide, RF; Haas, A; Yannuzzi, L
ISI:000168392103643
ISSN: 0146-0404
CID: 103644
Treatment of angiomatous lesions of the retina with photodynamic therapy [Meeting Abstract]
Rodriguez-Coleman, H; Spaide, R; Yannuzzi, LA
ISI:000168392102345
ISSN: 0146-0404
CID: 103645
Ring delimiting laser photoregulation of choroidal neovascularization [Meeting Abstract]
Spaide, RF; Yannuzzi, LA; Iida, T
ISI:000168392101229
ISSN: 0146-0404
CID: 103646
Sub-tenon's retrobulbar anecortave acetate with and without Visudyne (TM) photodynamic therapy (PDT) in patients with subfoveal choroidal neovascularization (CNV) in age-related macular degeneration (AMD) [Meeting Abstract]
Singerman, LJ; Yannuzzi, LA; Russell, S; Hudson, HL; Jerdan, J
ISI:000168392101237
ISSN: 0146-0404
CID: 103713
Differentiation between presumed ocular histoplasmosis syndrome and multifocal choroiditis with panuveitis based on morphology of photographed fundus lesions and fluorescein angiography
Parnell, J R; Jampol, L M; Yannuzzi, L A; Gass, J D; Tittl, M K
OBJECTIVE: To evaluate whether inactive cases of presumed ocular histoplasmosis syndrome (POHS) and multifocal choroiditis with panuveitis (MFC) can be differentiated from each other by their appearance on fundus photography and fluorescein angiography. METHODS: Two masked observers classified 50 patients' photographs (27 with fluorescein angiograms) as POHS, MFC, or 'indeterminate.' Twenty-five patients had known POHS and 25 had known MFC. Statistical analysis was performed to assess agreement and interrater reliability. RESULTS: Observer A classified 33 patients and was indeterminate on 17. Of the 33, he was correct on 26 (79% crude accuracy; kappa = 0.560; 95% confidence interval [CI], 0.286-0.834). Observer B classified 40 patients and was indeterminate on 10. Of the 40, he was correct on 33 (82% crude accuracy; kappa = 0.650; 95% CI, 0.422-0.878). Both observers ventured a diagnosis on 28 common patients. Of these, they selected the same diagnosis on 26 (93% crude agreement). When the 2 observers' diagnoses were compared and indeterminate patients were factored in, the kappa value was 0.408 (95% CI, 0.215-0.601). When the indeterminate patients are excluded, the kappa agreement increased to 0.825 (95% CI, 0.592-1). When pictures only were available, observer A and observer B kappa values against the gold standard were 0.625 (95% CI, 0.270-0.980) and 0.588 (95% CI, 0.235-0.940), respectively. The pictures-only kappa values for observer A vs observer B were 0.582 (95% CI, 0.316-0.848) with indeterminate patients factored in and 1.0 (95% CI, 1.0-1.0) when indeterminate patients were excluded. Pictures and fluorescein angiogram kappa values were 0.493 (95% CI, 0.076-0.909) for observer A and 0.706 (95% CI, 0.413-0.999) for observer B against the gold standard. For observer A vs observer B, the kappa value was 0.261 (95% CI, -0.002 to 0.524) with indeterminate patients factored in and 0.567 (95% CI, 0.032-1) excluding indeterminate patients. Sensitivity for all cases for observer A was 60% (+/-13%) for POHS and 94% (+/-6%) for MFC. For observer B, the sensitivity for all cases was 70% (+/-10%) for POHS and 95% (+/-5%) for MFC. CONCLUSIONS: Given adequate funduscopic information, the experienced observer can often accurately distinguish between POHS and MFC without the need for ancillary testing. Angiography in addition to fundus photography does not appear to increase diagnostic ability. There appears to be a higher sensitivity for MFC than for POHS
PMID: 11176981
ISSN: 0003-9950
CID: 103454
Dr. Donald M. Shafer - Obituary [Obituary]
Yannuzzi, LA
ISI:000173301000029
ISSN: 0275-004x
CID: 103714
Subretinal fibrosis and linear streaks in multifocal choroiditis [Case Report]
Fonseca, R A; Dantas, M A; Kaga, T; Yannuzzi, L A; Spaide, R F
PMID: 11146744
ISSN: 0003-9950
CID: 103455