Faculty Bibliography

We compared the clinical efficacy and side-effect profiles of aspirin, dextran 40, and low-molecular-weight heparin (enoxaparin) in preventing thromboembolic phenomena after hip fracture surgery. All patients admitted with a diagnosis of hip fracture to our institution between July 1, 1987, and December 31, 1999, were evaluated. Study inclusion criteria were age 65 years or older, previously ambulatory, cognitively intact, home-dwelling, and having a nonpathologic intertrochanteric or femoral neck fracture. Each patient received mechanical thromboprophylaxis (above-knee elastic stockings) and 1 pharmacologic agent (aspirin, dextran 40, or enoxaparin); patients who received aspirin were also given a calf sequential compression device. Meeting the selection criteria and included in the study were 917 patients. Findings included low incidence of thromboembolic phenomena (deep vein thrombosis, 0.5%-1.7%; pulmonary embolism, 0%-2.0%; fatal pulmonary embolism, 0%-0.5%) and no difference among the 3 pharmacologic agents in thromboembolic prophylaxis efficacy. Use of enoxaparin was associated with a significant increase (3.8%) in wound hematoma compared with dextran 40 (1.6%) and aspirin (2.4%) (P<.01). The 3 agents were found not to differ with respect to mortality, thromboembolic phenomena, hemorrhagic complications, or wound complications.

Posttraumatic arthritis is a degenerative arthritis of the glenohumeral joint that develops after previous fracture and is characterized by bony deformity and soft tissue changes. Articular incongruity in the absence of significant deformity is a good prognostic factor, as is the ability to correct all osseous and soft tissue abnormalities. The need for greater tuberosity osteotomy is a poor prognostic factor. Poor results may also be due to irreparable soft tissue deficits, tension on the tuberosities interfering with healing, limited healing potential in the presence of nonunion, poor patient compliance, and prosthetic design not being conducive to tuberosity reattachment

The high incidence of preoperative silent pulmonary embolisms (PEs) among elderly patients with hip fractures has led some authors to recommend making acquisition of arterial blood gas (ABG) levels a routine part of the preoperative workup. In the study reported here, we retrospectively reviewed 254 patients in our hip-fracture database and determined that ABG levels have poor positive predictive value for PEs and add little to the positive predictive value or negative predictive value of careful clinical examination. Therefore, we do not recommend making acquisition of ABG levels a routine part of the preoperative evaluation