Faculty Bibliography

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252

Multiple sclerosis. 2021:27(2_SUPPL):292-293.DOI:

Meaning and purpose for people with multiple sclerosis: quality of life reflects more than apparent physical ability [Meeting Abstract]

Kaczmarek, O.; Sethi, A.; Malone, E.; Doshi, M.; Mardonov, J.; Bumstead, B.; Buhse, M.; Zarif, M.; Wilken, J.; Gudesblatt, M.
ISI:000706771301085
ISSN: 1352-4585
CID: 5342902
Multiple sclerosis. 2021:27(1_SUPPL):113-114.DOI:

Multiple Sclerosis, Cognition and the Ability to Participate in Social Roles and Activities: Disease Impact Beyond Physical Disability [Meeting Abstract]

Kaczmarek, O.; Petroski, J.; Kodym, C.; Bumstead, B.; Buhse, M.; Lund, D.; Zarif, M.; Golan, D.; Wilken, J.; Gudesblatt, M.
ISI:000669008200237
ISSN: 1352-4585
CID: 5342852
Multiple sclerosis. 2021:27(1_SUPPL):36-37.DOI:

Efficacy and Safety Outcomes After Transition From Glatiramer Acetate to Diroximel Fumarate: Results From the Phase 3 EVOLVE-MS-1 Study [Meeting Abstract]

Wray, S.; Wundes, A.; Arnold, D. L.; Singer, B. A.; Bowen, J. D.; Hunter, S. F.; Gudesblatt, M.; Chen, H.; Lyons, J.; Melikov, M.; Mendoza, J. P.; Messer, J.; Naismith, R. T.
ISI:000669008200077
ISSN: 1352-4585
CID: 5342832
Multiple sclerosis. 2021:27(2_SUPPL):362-363.DOI:

Multiple sclerosis, quantitative MRI maging, immune profile: exploration of a potential relationship between brain atrophy and IgG sub-class profiles in a population of people with multiple sclerosis [Meeting Abstract]

Dasaro, C.; Srinivasan, J.; Kaczmarek, O.; Bumstead, B.; Buhse, M.; Zarif, M.; Sima, D.; Smeets, D.; Gudesblatt, M.
ISI:000706771301203
ISSN: 1352-4585
CID: 5342942
Multiple sclerosis. 2021:27(2_SUPPL):302-303.DOI:

Multiple sclerosis, medication management, health literacy and accumulative cognitive impairment: is perception sufficient for performance? [Meeting Abstract]

Sethi, A.; Kaczmarek, O.; Petroski, J.; Bumstead, B.; Buhse, M.; Zarif, M.; Wilken, J.; Golan, D.; Krieger, S.; Doniger, G.; Gudesblatt, M.
ISI:000706771301102
ISSN: 1352-4585
CID: 5342912
Movement disorders. 2021:36(SI):S303-S304.DOI:

Parkinson's Disease, Cognitive Function and Medication Management: A Problem in Routine Care [Meeting Abstract]

Tierney, P.; Kaczmarek, O.; Sethi, A.; Bumstead, B.; Buhse, M.; Kravis, E.; Anand, B.; Zarif, M.; Gudesblatt, M.
ISI:000694886400021
ISSN: 0885-3185
CID: 5342862
Multiple sclerosis. 2021:27(1_SUPPL):113-113.DOI:

Multiple Sclerosis and the Ability to Participate in Social Roles and Activities: Disease Impact Beyond Physical Disability [Meeting Abstract]

Kaczmarek, O.; Petroski, J.; Zodiatis, E.; Bumstead, B.; Buhse, M.; Zarif, M.; Golan, D.; Wilken, J.; Gudesblatt, M.
ISI:000669008200236
ISSN: 1352-4585
CID: 5342842
Multiple sclerosis. 2021:27(2_SUPPL):667-668.DOI:

Multiple sclerosis, natalizumab, cognition: multi-domain cognitive NEDA [Meeting Abstract]

Kaczmarek, O.; Sethi, A.; Kodym, C.; Bumstead, B.; Buhse, M.; Zarif, M.; Golan, D.; Wilken, J.; Gudesblatt, M.
ISI:000706771302185
ISSN: 1352-4585
CID: 5342952
Movement disorders. 2021:36(SI):S506-S506.DOI:

Parkinson's Disease, Cognitive Function: Exploration of the Relation of Multi-Domain Computerized Cognitive Testing and IADL (instrumental activities of daily living) and Neuro-QoL Upper Extremity Function (Fine Motor, ADL) [Meeting Abstract]

Tierney, P.; Kaczmarek, O.; Sethi, A.; Bumstead, B.; Buhse, M.; Kravis, E.; Anand, B.; Zarif, M.; Gudesblatt, M.
ISI:000694886400458
ISSN: 0885-3185
CID: 5342882
Neurology. Clinical practice. 2020:10(6):510-519.DOI: 10.1212/CPJ.0000000000000800

Lymphocyte reconstitution after DMF discontinuation in clinical trial and real-world patients with MS

Chan, Andrew; Rose, John; Alvarez, Enrique; Bar-Or, Amit; Butzkueven, Helmut; Fox, Robert J; Gold, Ralf; Gudesblatt, Mark; Haartsen, Jodi; Spelman, Tim; Wright, Katy; Ferraro, Diana; Sola, Patrizia; Hodgkinson, Suzanne; Kalincik, Tomas; Lechner-Scott, Jeannette; McGuigan, Christopher; Spach, Karen; Chen, Chongshu; Fam, Sami; Wu, Fan; Miller, Catherine
BACKGROUND:Delayed-release dimethyl fumarate (DMF) has demonstrated robust efficacy in treating patients with relapsing-remitting multiple sclerosis. Decreases in absolute lymphocyte count (ALC) are a well-known pharmacodynamic effect of DMF treatment, but lymphocyte recovery dynamics are not well characterized after discontinuation of DMF. METHODS:Data sources included the Biogen DMF integrated clinical trial data set, a retrospective US chart abstraction study, and data from MSBase. We assessed rate and time course of lymphocyte reconstitution after DMF discontinuation. RESULTS:/L was 12-18 months vs 2-3 months in patients with lymphopenia persisting <6 months. CONCLUSIONS:The majority of patients who discontinued DMF due to lymphopenia experienced ALC reconstitution within 2-4 months following DMF discontinuation. This may help guide clinicians in managing patients who develop lymphopenia during DMF treatment. Prolonged lymphopenia on DMF treatment is associated with slow lymphocyte recovery after DMF discontinuation.
PMCID:7837440
PMID: 33510947
ISSN: 2163-0402
CID: 5342282