Try a new search

Format these results:

Searched for:

in-biosketch:true

person:hagiwm01

Total Results:

80


Potential Role of PET/MRI for Imaging Metastatic Lymph Nodes in Head and Neck Cancer

Kim, Sungheon Gene; Friedman, Kent; Patel, Sohil; Hagiwara, Mari
OBJECTIVE: This article explores recent developments in PET and MRI, separately or combined, for assessing metastatic lymph nodes in patients with head and neck cancer. CONCLUSION: The synergistic role of PET and MRI for imaging metastatic lymph nodes has not been fully explored. To facilitate the understanding of the areas that need further investigation, we discuss potential mechanisms and evidence reported so far, as well as future directions and challenges for continued development and clinical research.
PMCID:5756667
PMID: 27163282
ISSN: 1546-3141
CID: 2107572

Extrinsic Esophageal Compression by Cervical Osteophytes in Diffuse Idiopathic Skeletal Hyperostosis: A Contraindication to Transesophageal Echocardiography?

Chang, Kevin; Barghash, Maya; Donnino, Robert; Freedberg, Robin S; Hagiwara, Mari; Bennett, Genevieve; Benenstein, Ricardo; Saric, Muhamed
Contraindications to transesophageal echocardiography (TEE) include various esophageal pathologies, but compression of the esophagus by vertebral osteophytes is not listed in the current American Society of Echocardiography guidelines. We report a case of diffuse idiopathic skeletal hyperostosis (DISH) in an 81-year-old man who had incidentally been found to have extrinsic esophageal compression by cervical osteophytes prior to a proposed TEE. The incidence of esophageal perforation in patients with DISH and vertebral osteophytes is not well documented. We believe these patients are at increased risk of esophageal perforation during TEE, and thus, TEE may be relatively contraindicated in patients with DISH.
PMID: 26603685
ISSN: 1540-8175
CID: 1856922

Orbital lesions with low signal intensity on T2-weighted imaging

Hoch, M; Win, W; Hagiwara, M; Fatterpekar, G; Patel, S
The purpose of the present review is to discuss and display orbital lesions that demonstrate hypo-intense signal on T2-weighted images (T2WI). The physical basis for hypo-intense signal on T2WI produced by various substances is discussed. Orbital lesions that are hypo-intense on T2WI are subsequently reviewed, including a discussion on their composition as well as relevant clinical and imaging clues that may aid in their diagnosis.
PMID: 26602937
ISSN: 1365-229x
CID: 1856912

Use of computed tomography to assess volume change after endoscopic orbital decompression for Graves' ophthalmopathy

Schiff, Bradley A; McMullen, Caitlin P; Farinhas, Joaquim; Jackman, Alexis H; Hagiwara, Mari; McKellop, Jason; Lui, Yvonne W
BACKGROUND: Orbital decompression is frequently performed in the management of patients with sight-threatening and disfiguring Graves' ophthalmopathy. The quantitative measurements of the change in orbital volume after orbital decompression procedures are not definitively known. Furthermore, the quantitative effect of septal deviation on volume change has not been previously analyzed. OBJECTIVES: To provide quantitative measurement of orbital volume change after medial and inferior endoscopic decompression and describe a straightforward method of measuring this change using open-source technologies. A secondary objective was to assess the effect of septal deviation on orbital volume change. METHODS: A retrospective review was performed on all patients undergoing medial and inferior endoscopic orbital decompression for Graves' ophthalmopathy at a tertiary care academic medical center. Pre-operative and post-operative orbital volumes were calculated from computed tomography (CT) data using a semi-automated segmenting technique and Osirix, an open-source DICOM reader. Data were collected for pre-operative and post-operative orbital volumes, degree of septal deviation, time to follow-up scan, and individual patient Hertel scores. RESULTS: Nine patients (12 orbits) were imaged before and after decompression. Mean pre-operative orbital volume was 26.99cm(3) (SD=2.86cm(3)). Mean post-operative volume was 33.07cm(3) (SD=3.96cm(3)). The mean change in volume was 6.08cm(3) (SD=2.31cm(3)). The mean change in Hertel score was 4.83 (SD=0.75). Regression analysis of change in volume versus follow-up time to imaging indicates that follow-up time to imaging has little effect on change in volume (R=-0.2), and overall mean maximal septal deviation toward the operative side was -0.5mm. Negative values were attributed to deviation away form the operative site. A significant correlation was demonstrated between change in orbital volume and septal deviation distance site (R=0.66), as well as between change in orbital volume and septal deviation angle (R=0.67). Greater volume changes were associated with greater degree of septal deviation away from the surgical site, whereas smaller volume changes were associated with greater degree of septal deviation toward the surgical site. CONCLUSION: A straightforward, semi-automated segmenting technique for measuring change in volume following endoscopic orbital decompression is described. This method proved useful in determining that a mean increase of approximately 6cm in volume was achieved in this group of patients undergoing medial and inferior orbital decompression. Septal deviation appears to have an effect on the surgical outcome and should be considered during operative planning.
PMID: 26545461
ISSN: 1532-818x
CID: 1826112

Fungal Sinusitis

Raz, Eytan; Win, William; Hagiwara, Mari; Lui, Yvonne W; Cohen, Benjamin; Fatterpekar, Girish M
Fungal sinusitis is characterized into invasive and noninvasive forms. The invasive variety is further classified into acute, chronic and granulomatous forms; and the noninvasive variety into fungus ball and allergic fungal sinusitis. Each of these different forms has a unique radiologic appearance. The clinicopathologic and corresponding radiologic spectrum and differences in treatment strategies of fungal sinusitis make it an important diagnosis for clinicians and radiologists to always consider. This is particularly true of invasive fungal sinusitis, which typically affects immuno compromised patients and is associated with significant morbidity and mortality. Early diagnosis allows initiation of appropriate treatment strategies resulting in favorable outcome.
PMID: 26476380
ISSN: 1557-9867
CID: 1803842

Continuous Versus Sequential Acquisition Head Computed Tomography: A Phantom and Clinical Image Quality Comparative Study

Davis, Adam J; Ozsvath, Jessica; Vega, Emilio; Babb, James S; Hagiwara, Mari; George, Ajax
OBJECTIVE: Sequential computed tomography (CT) technique remains the most common protocol for CT evaluation of the head despite nearly universal adoption of continuous technique for all other body parts. This may be attributable to the belief by radiologists that this technique is superior to helical scanning uniquely for this indication. This study attempts to clarify the issue. METHODS: A phantom evaluation and a prospective randomized clinical image quality trial were performed comparing sequential and helical technique using the most current generation 128-row detector CT scanner. RESULTS: Phantom evaluation demonstrated equivalence between the 2 techniques for low-contrast resolution and line pair spatial discrimination. Continuous scanning provided the highest contrast-to-noise ratio. There was no significant difference between the 2 techniques regarding image quality except for cortical visualization at the cerebral hemispheres, which was subtly but significantly superior for sequential technique. CONCLUSIONS: Head CT image quality for sequential and continuous techniques are virtually equivalent.
PMID: 26359580
ISSN: 1532-3145
CID: 1772632

Evaluation of the orbit using contrast-enhanced radial 3D fat-suppressed T1-weighted gradient-echo (Radial-VIBE) sequence

Bangiyev, Lev; Raz, Eytan; Block, Tobias; Hagiwara, Mari; Wu, Xin; Yu, Eugene; Fatterpekar, Girish M
OBJECTIVES: Contrast-enhanced fat-suppressed T1-weighted-2D-TSE and MPRAGE sequence with water excitation are routinely obtained to evaluate orbit pathology. However, these sequences can be marred by artifacts. The Radial-VIBE sequence is a motion-robust fat-suppressed T1W sequence which has demonstrated value in pediatric and body imaging. The purpose of our study is to evaluate its role in assessing the orbit, and to compare it with routinely acquired sequences. METHODS: A HIPAA-compliant and IRB-approved retrospective study was performed in 46 patients (age range: 1-81 years) who underwent orbit studies on a 1.5-T MRI using contrast-enhanced Radial-VIBE, MPRAGE and 2D-TSE sequences. Two radiologists blinded to the sequence analyzed evaluated multiple parameters of image quality including motion artifact, degree of fat-suppression, clarity of choroidal enhancement, intraorbital vessels, extraocular muscles, optic nerves, brain parenchyma and evaluation of pathology. Each parameter was assessed on a 5-point scale, with a higher score indicating the more optimal exam. Mix-model analysis of variance and interobserver variability were assessed. RESULTS: Radial-VIBE demonstrated superior quality (p<0.001) for all orbit parameters when compared to MPRAGE and 2D-TSE. Interobserver agreement demonstrated average fair-to -good agreement for: degree of motion artifact (0.745), fat suppression (0.678), clarity of choroidal enhancement (0.688), vessels (0.655), extraocular muscles (0.675), optic nerves (0.518), brain parenchyma (0.710), and evaluation of pathology (0.590). CONCLUSION: Radial-VIBE sequence demonstrates superior image quality when evaluating the orbits as compared to conventional MPRAGE and 2D-TSE sequences. Advances in knowledge: Radial-VIBE employs unique non-Cartesian k-space sampling in a radial or spoke-wheel fashion which provides superior image quality improving diagnostic capability in evaluation of the orbits.
PMCID:4730962
PMID: 26194589
ISSN: 1748-880x
CID: 1683772

Parry Romberg Syndrome: 7 Cases and Literature Review

Wong, M; Phillips, C D; Hagiwara, M; Shatzkes, D R
Parry Romberg syndrome is a rare progressive hemiatrophy of the face that typically occurs in children and young adults and has a peculiar progression that ceases without apparent cause after a highly variable period. Only a subset of patients with Parry Romberg syndrome will develop secondary neurologic or ophthalmologic symptoms, and prognosis is highly variable. Inconsistency in the pattern of atrophy and the development of associated symptoms in patients with Parry Romberg syndrome has made it challenging to diagnose, prognosticate, and treat. The precise etiology of this disease remains unknown, but some authors have implicated sympathetic cervical ganglion dysfunction, abnormal embryogenesis, autoimmune and inflammatory mechanisms, or vasculopathy as potential causes. We present 7 cases of Parry Romberg syndrome and their associated clinical and imaging findings with specific attention to the radiographic characteristics of this disease.
PMID: 26066627
ISSN: 1936-959x
CID: 1669702

EFFECTS OF EVEROLIMUS ON MENINGIOMA GROWTH IN PATIENTS WITH NEUROFIBROMATOSIS TYPE 2 [Meeting Abstract]

Osorio, Diana; Filatov, Alexander; Hagiwara, Mari; Mitchell, Carole; Wisoff, Jeffrey; Golfinos, John; Roland, J. Thomas; Allen, Jeffrey; Karajannis, Matthias
ISI:000361304800159
ISSN: 1522-8517
CID: 2964282

Age-Related Changes in Pharyngeal Lumen Size: A Retrospective MRI Analysis

Molfenter, Sonja M; Amin, M R; Branski, R C; Brumm, J D; Hagiwara, M; Roof, S A; Lazarus, C L
Age-related loss of muscle bulk and strength (sarcopenia) is often cited as a potential mechanism underlying age-related changes in swallowing. Our goal was to explore this phenomenon in the pharynx, specifically, by measuring pharyngeal wall thickness and pharyngeal lumen area in a sample of young versus older women. MRI scans of the neck were retrospectively reviewed from 60 women equally stratified into three age groups (20s, 60s, 70+). Four de-identified slices were extracted per scan for randomized, blinded analysis: one mid-sagittal and three axial slices were selected at the anterior inferior border of C2 and C3, and at the pit of the vallecula. Pixel-based measures of pharyngeal wall thickness and pharyngeal lumen area were completed using ImageJ and then converted to metric units. Measures of pharyngeal wall thickness and pharyngeal lumen area were compared between age groups with one-way ANOVAs using Sidak adjustments for post-hoc pairwise comparisons. A significant main effect for age was observed across all variables whereby pharyngeal wall thickness decreased and pharyngeal lumen area increased with advancing age. Pairwise comparisons revealed significant differences between 20s versus 70+ for all variables and 20s versus 60s for all variables except those measured at C2. Effect sizes ranged from 0.54 to 1.34. Consistent with existing sacropenia literature, the pharyngeal muscles appear to atrophy with age and consequently, the size of the pharyngeal lumen increases.
PMID: 25750039
ISSN: 0179-051x
CID: 1494562