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Cryopreserved bone allograft for the treatment of shoulder instability with glenoid defect

Abdelshahed, Mina M; Shamah, Steven D; Mahure, Siddharth A; Mollon, Brent; Kwon, Young W
The purpose of this study was to examine outcomes after cryopreserved tri-cortical iliac crest allograft reconstruction for glenoid bone loss in patients with shoulder instability. 10 patients completed the required assessments at a mean follow up of 4.5 years. At final follow up, mean ASES was 92 ± 12, mean WOSI was 315 ± 319, with good range of motion. None of the final radiographs demonstrated graft resorption or failure of hardware. The data demonstrated that patients who were treated with glenoid bone grafting with cryopreserved tri-cortical iliac crest allograft can expect good range of motion and functional capacity.
PMCID:5895933
PMID: 29657478
ISSN: 0972-978x
CID: 3040802

Risk factors for recurrent instability or revision surgery following arthroscopic Bankart repair

Mahure, S A; Mollon, B; Capogna, B M; Zuckerman, J D; Kwon, Y W; Rokito, A S
Aims The factors that predispose to recurrent instability and revision stabilization procedures after arthroscopic Bankart repair for anterior glenohumeral instability remain unclear. We sought to determine the rate and risk factors associated with ongoing instability in patients undergoing arthroscopic Bankart repair for instability of the shoulder. Materials and Methods We used the Statewide Planning and Research Cooperative System (SPARCS) database to identify patients with a diagnosis of anterior instability of the shoulder undergoing arthroscopic Bankart repair between 2003 and 2011. Patients were followed for a minimum of three years. Baseline demographics and subsequent further surgery to the ipsilateral shoulder were analyzed. Multivariate analysis was used to identify independent risk factors for recurrent instability. Results A total of 5719 patients were analyzed. Their mean age was 24.9 years (sd 9.3); 4013 (70.2%) were male. A total of 461 (8.1%) underwent a further procedure involving the ipsilateral shoulder at a mean of 31.5 months (sd 23.8) postoperatively; 117 (2.1%) had a closed reduction and 344 (6.0%) had further surgery. Revision arthroscopic Bankart repair was the most common subsequent surgical procedure (223; 65.4%). Independent risk factors for recurrent instability were: age < 19 years (odds ratio 1.86), Caucasian ethnicity (hazard ratio 1.42), bilateral instability of the shoulder (hazard ratio 2.17), and a history of closed reduction(s) prior to the initial repair (hazard ratio 2.45). Revision arthroscopic Bankart repair was associated with significantly higher rates of ongoing persistent instability than revision open stabilization (12.4% vs 5.1%, p = 0.041). Conclusion The incidence of a further procedure being required in patients undergoing arthroscopic Bankart repair for anterior glenohumeral instability was 8.1%. Younger age, Caucasian race, bilateral instability, and closed reduction prior to the initial repair were independent risk factors for recurrent instability, while subsequent revision arthroscopic Bankart repair had significantly higher rates of persistent instability than subsequent open revision procedures. Cite this article: Bone Joint J 2018;100-B:324-30.
PMID: 29589497
ISSN: 2049-4408
CID: 3008952

Arthroscopic Repair of Type II SLAP Tears Using Suture Anchor Technique

Hamula, Mathew; Mahure, Siddharth A; Kaplan, Daniel J; Mollon, Brent; Zuckerman, Joseph D; Kwon, Young W; Rokito, Andrew S
Arthroscopic SLAP tear repair has become an increasingly used treatment for patients presenting with symptomatic SLAP tears after failed nonoperative management. Debridement, SLAP repair, and open or arthroscopic biceps tenodesis or tenotomy have been used for the treatment of SLAP tears. Various techniques for repair have been described, and furthermore, there is a high incidence of concomitant pathology of the shoulder. Repair remains an excellent option in isolated SLAP tears amenable to repair, with excellent outcomes in well-indicated patients. We present a method for repairing a SLAP tear using standard suture anchor fixation, anterior and posterior portals, and an accessory portal of Wilmington. Adequate labral repair can be achieved with this technique in patients with no concomitant biceps pathology. This report highlights this technique for SLAP repair in patients with isolated symptomatic SLAP tears that have failed conservative management.
PMCID:5766350
PMID: 29349009
ISSN: 2212-6287
CID: 2915302

+/- subscapularis sparing total shoulder arthroplasty: A prospective, double blinded, randomized clinical trial [Meeting Abstract]

Kwon, Y W; Zuckerman, J D
Introduction: While total shoulder arthroplasty (TSA) is generally associated with good to excellent outcomes in majority of patients, the integrity and the function of the subscapularis tendon may be compromised after the procedure and lead to inferior outcomes. Therefore, the efficacy of a subscapularis sparing TSA procedure was evaluated in a prospective, double blinded, randomized study. Methods: With IRB approval, patients with end stage osteoarthritis of the shoulder were enrolled into a prospective clinical trial from 2010 to 2014. These patients were randomized into two groups. Group 1 patients were treated with TSA using the subscapularis sparing surgical approach in which the prosthesis was inserted entirely through the rotator interval without violating the subscapularis tendon (SPARING). Group 2 patients were treated with TSA using the standard surgical approach with subscapularis tenotomy (STANDARD). Both the patient and the evaluators remained "blinded" to the surgical approach throughout the study period. Minimum 2 year outcome data was collected using the visual analog score (VAS) for pain and the American Shoulder and Elbow Surgeon (ASES) outcome score. Results: A total of 107 shoulders were enrolled (57 SPARING, 50 STANDARD). Of these, 14 TSA procedures could not be completed as initially randomized. In addition, 3 patients expired (unrelated to the procedure), 7 patients withdrew from the study, and 2 moved away. Of the remaining 81 patients, 2 year outcome data could not be collected from another 11. Thus, complete 2 year outcome data was collected from 32 SPARING and 38 STANDARD patients at an average follow up of 31.1 and 34.4 months, respectively. The ASES score and VAS for the SPARING group improved significantly from 29.3 +/- 12.5 and 6.6 +/- 2.1 to 82.6 +/- 18.8 and 1.6 +/- 2.2 (mean +/- standard deviation). Similarly, the ASES score and VAS for the STANDARD group also improved significantly from 32.8 +/- 16.1 and 6.3 +/- 2.4 to 87.1 +/- 14.5 and 1.0 +/- 1.7. In comparison to their pre-operative status, the ASES score for the SPARING and the STANDARD groups improved 53.9 +/- 22.3 and 54.0 +/- 18.7 points, respectively. The VAS for the SPARING and the STANDARD groups also improved 5.1 +/- 3.1 and 5.3 +/- 2.5 points, respectively. Neither of these differences between the SPARING and the STANDARD groups reached statistical significance. Complication profiles were similar in both groups with 3 in the SPARING group and 2 patients in the STANDARD group requiring revision surgery during the study period. Discussion: At a short term follow up, the outcome of TSA using the subscapularis sparing surgical approach was similar to that after TSA using the standard surgical approach. Future studies with longer follow up of these patients will be required to document the potential benefits of this surgical technique
EMBASE:619247594
ISSN: 1532-6500
CID: 2860492

Impact of Diabetes on Perioperative Complications in Patients Undergoing Elective Total Shoulder Arthroplasty

Mahure, Siddharth; Mollon, Brent; Quien, Mary; Karia, Raj; Zuckerman, Joseph; Kwon, Young
INTRODUCTION: Diabetes has been associated with negative outcomes following orthopaedic surgery. While previous studies have reported on diabetes-associated complications in shoulder arthroplasty, those cohorts were heterogeneous in terms of patient population, nature of elective surgery, and arthroplasty type. Given that the number of elective total shoulder arthroplasties (TSAs) performed has grown substantially in volume and is predicted to rise even further, it is important to recognize the role that diabetes may play in developing in-hospital complications within a more homogenous sample of patients undergoing elective TSA. METHODS: The Nationwide Inpatient Sample (NIS) was searched for the year 2012 to identify all patients undergoing elective TSA. Patients with diabetes were identified, and differences regarding demographics and in-hospital outcomes were compared to non-diabetics using multivariate logistic regression. RESULTS: A total of 44,050 patients underwent elective total shoulder arthroplasty (TSA) in 2012. Diabetic patients tended to be older, of minority racial status, and had a greater medical comorbidity burden. When controlling for preoperative factors and comorbidities, diabetes was an independent risk factor for non-home bound discharge (OR 1.285; 95% CI 1.093-1.509, p = 0.002), length of stay in 75th percentile (OR 1.390; 95% CI 1.233-1.567, p < 0.001), total charges in the 75th percentile (OR 1.136; 95% CI 1.006-1.283, p = 0.040), and postoperative acute renal failure (OR 1.460; 1.002-2.128, p = 0.048). CONCLUSION: Diabetes was associated with marginal increases in non-home bound discharge, length of stay, and total charges, following elective TSA. Subgroup analysis revealed that diabetic patients undergoing reverse total shoulder arthroplasty (rTSA) have higher comorbidity burden and worse outcomes than diabetic patients undergoing anatomic total shoulder arthroplasty (aTSA).
PMID: 28902601
ISSN: 2328-5273
CID: 2709662

Transcutaneous electrical nerve stimulation for postoperative pain relief after arthroscopic rotator cuff repair: a prospective double-blinded randomized trial

Mahure, Siddharth A; Rokito, Andrew S; Kwon, Young W
BACKGROUND: Arthroscopic rotator cuff repair (ARCR) can be associated with significant postoperative pain. Concern for opioid abuse has led surgeons to identify alternative, efficacious methods of postoperative analgesia. To determine whether transcutaneous electrical nerve stimulation (TENS) can have a similarly beneficial effect after shoulder procedures, we conducted a prospective double-blinded randomized trial in patients undergoing outpatient ARCR. METHODS: All patients undergoing ARCR of a full-thickness rotator cuff tear by the senior authors were identified. Patients with a history of recent narcotic use or prior narcotic abuse and those under management of a pain control specialist were excluded. Patients were randomized into 2 groups, active or placebo TENS, and used the device for 4 sessions/day for 45 minutes/session for the first postoperative week. All patients received Percocet 5/325 mg (oxycodone/acetaminophen) for use as rescue pain pills. One-week narcotic consumption and visual analog scale pain scores were compared between groups. RESULTS: The final analysis included 37 patients (21 active,16 placebo). Baseline and procedural differences were not different between groups. At 1 week postoperatively, patients in the active group had significantly lower pain scores (3.6 +/- 2.1 vs. 5.8 +/- 1.2; P= .008). Postoperative Percocet consumption during the initial 48 hours (12.8 +/- 4.7 vs. 17.2 +/- 6.3; P = .020) and during the first week (25.2 +/- 9.9 vs. 33.8 +/- 14.3; P = .037) was also significantly lower in the active group. CONCLUSION: Results from this prospective double-blinded randomized trial demonstrate that compared with placebo TENS, active TENS can result in significantly less pain and reduced opioid use in the immediate postoperative period after ARCR, suggesting that TENS may be potentially useful in a multimodal approach to managing postoperative pain.
PMID: 28735847
ISSN: 1532-6500
CID: 2669342

Comparison of general versus isolated regional anesthesia in total shoulder arthroplasty: A retrospective propensity-matched cohort analysis

Ding, David Y; Mahure, Siddharth A; Mollon, Brent; Shamah, Steven D; Zuckerman, Joseph D; Kwon, Young W
BACKGROUND: Intraoperative anesthetic typically consists of either general anesthesia (GA) or isolated regional anesthesia (RA). METHODS: A retrospective propensity-matched cohort analysis on patients undergoing TSA was performed to determine differences between GA and RA in regard to patient population, complications, LOS and hospital readmission. RESULTS: 4158 patients underwent TSA with GA or isolated RA. Propensity-matching resulted in 912 patients in each cohort. RA had lower overall in-hospital complications and greater homebound discharge disposition with lower 90-day readmission rates than GA. CONCLUSION: After TSA, isolated RA was associated with lower in-hospital complications, readmission rates and odds of hospital readmission than GA.
PMCID:5537444
PMID: 28794581
ISSN: 0972-978x
CID: 2663922

Risk factors for subsequent instability or revision surgery following arthroscopic bankart repair [Meeting Abstract]

Mahure, S A; Mollon, B; Capogna, B M; Zuckerman, J D; Kwon, Y W; Rokito, A S
Background: Factors contributing to recurrent instability and revision stabilization procedures after isolated arthroscopic stabilization of anterior glenohumeral instability have not been examined in a Statewide cohort. Additionally, practice patterns of the management of the failed Bankart repair are unclear. We sought to identify the type, rate and risk factors associated with subsequent ipsilateral shoulder procedures in a large cohort of individuals undergoing arthroscopic stabilizations for anterior shoulder instability. Methods: The New York State Department of Health's Statewide Planning and Research Cooperative Systems (SPARCS) database was examined from 2003 to 2011 to identify all patients with a primary diagnosis of anterior shoulder instability (ICD-9-CM codes 831.01, 718.81 and 718.31) undergoing outpatient arthroscopic capsulorraphy (CPT code 29806). Patients younger than 10 or older than 60 years of age, and entries with missing data, were excluded. Patients were longitudinally followed for a minimum of three years (through 2014). Baseline demographics and all subsequent ipsilateral outpatient shoulder procedures were collected. SAS version 9.3 (Cary, NC) was used for data collection and statistical analysis. Results: We identified 5,719 unique patients who met the inclusion criteria. Mean patient age was 24.9 + /- 9.3 years, and 70.2% of the sample was male. A total of 461 (8.1%) patients underwent subsequent ipsilateral shoulder instability interventions a mean of 31.5 + /- 23.8 months after the initial stabilization procedure (2.1% had closed reduction alone; 6.0% had repeat instability surgery + /- closed reduction). Repeat arthroscopic capsulorraphy was the most common subsequent procedure (48.8%). Patients undergoing procedures for subsequent shoulder instability were younger (22.6 + /- 8.6 vs. 25.1 + /- 9.4 years of age, P < .001). Evidence of additional instability following arthroscopic Bankart was independently associated with age 19 years or younger (HR 1.82; 95% CI 1.50-2.21; P < .001), Caucasian ethnicity (HR 1.38; 95% CI 1.11-1.71; P = .003), evidence of bilateral shoulder instability (HR 1.54; 95% CI 1.06-2.23; P = .023) and a history of closed reduction(s) prior to initial arthroscopic Bankart repair (HR 2.45; 95% CI 1.90-3.15 P = < .001). Gender and surgeon volume was not associated with subsequent instability procedures. When followup was normalized to three years to allow for between year comparisons, year of surgery did not predict subsequent shoulder instability. Conclusion: Patients undergoing arthroscopic stabilization of anterior glenohumeral instability in New York State had an 8.1% chance of undergoing subsequent ipsilateral instability procedures. Younger age, Caucasian race, bilateral glenohumeral instability and closed reduction prior to initial Bankart repair were independent risk factors for additional instability procedures. The most common second surgical procedure was a repeat arthroscopic stabilization (Table 1). (Table Presented)
EMBASE:616241023
ISSN: 1058-2746
CID: 2579712

Two-stage revision for infected shoulder arthroplasty after minimum 2-year follow-up [Meeting Abstract]

Buchalter, D B; Mahure, S A; Mollon, B; Yu, S; Kwon, Y W; Zuckerman, J D
Introduction: Periprosthetic shoulder infections (PSIs) are challenging to treat and often result in significant patient morbidity. Without a standardized treatment protocol, PSIs are often managed similarly to periprosthetic hip and knee infections. Because two-stage revision is the gold standard for treating periprosthetic hip and knee infections, we performed a case series and literature review to determine its effectiveness in PSIs. Methods: We identified nineteen patients from our institution that were treated with two-stage revision after presenting with a PSI. Minimum follow-up for all patients was 2 years. Mean patient age was 63 +/- 9 years, 14/19 patients were male, and average BMI was 30.8 +/- 5.8. Average time from index arthroplasty to treatment was 40 months, 8/13 positive cultures were P. acnes, and 9/19 patients had multiple shoulder operations before presenting with infection. Results: After a mean follow up of 63 months (Range 25-184 months), 15/19 patients in our study were successfully treated for PSI. Average postoperative ASES score was 69 (32-98) and average postoperative forward elevation was significantly increased from 58 to 119 degrees (P < .001). The incidence of recurrent infection was 26%; the rate of non-infection complications was 16% for a total complication rate of 42%. Conclusion: In patients with PSIs, especially those with intractable, chronic infections, a two-stage revision represents a viable treatment option for eradicating infection and restoring function. However, it is important to recognize the risk of recurrent infection and postoperative complications in this challenging patient population
EMBASE:616240969
ISSN: 1058-2746
CID: 2579722

Two-stage revision for infected shoulder arthroplasty

Buchalter, Daniel B; Mahure, Siddharth A; Mollon, Brent; Yu, Stephen; Kwon, Young W; Zuckerman, Joseph D
BACKGROUND: Periprosthetic shoulder infections (PSIs) are challenging to treat and often result in significant patient morbidity. Without a standardized treatment protocol, PSIs are often managed similarly to periprosthetic hip and knee infections. Because 2-stage revision is the gold standard for treating periprosthetic hip and knee infections, we performed a case series and literature review to determine its effectiveness in PSIs. METHODS: We identified 19 patients (14 men) from our institution who were treated with a 2-stage revision after presenting with a PSI. Mean patient age was 63 +/- 9 years, and average body mass index was 30.8 +/- 5.8. The average time from the index arthroplasty to treatment was 40 months, 8 of 13 positive cultures were Propionibacterium acnes, and 9 of 19 patients had multiple shoulder operations before presenting with infection. Minimum follow-up for all patients was 2 years. RESULTS: After a mean follow-up of 63 months (range, 25-184 months), 15 of 19 patients in our study were successfully treated for PSI. Average postoperative American Shoulder and Elbow Surgeons (ASES) Shoulder Assessment score was 69 (range, 32-98) and average postoperative forward elevation was significantly increased from 58 degrees to 119 degrees (P < .001). The incidence of recurrent infection was 26%. The rate of noninfection complications was 16%, for a total complication rate of 42%. CONCLUSION: In patients with PSIs, especially those with intractable, chronic infections, a 2-stage revision represents a viable treatment option for eradicating infection and restoring function. However, it is important to recognize the risk of recurrent infection and postoperative complications in this challenging patient population.
PMID: 27887875
ISSN: 1532-6500
CID: 2314602