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Utilization of a Novel Opioid-Sparing Protocol in Primary Total Hip Arthroplasty Results in Reduced Opiate Consumption and Improved Functional Status
Feng, James E; Mahure, Siddharth A; Waren, Daniel P; Lajam, Claudette M; Slover, James D; Long, William J; Schwarzkopf, Ran M; Macaulay, William B; Davidovitch, Roy I
BACKGROUND:Total hip arthroplasty (THA) candidates have historically received high doses of opioids within the perioperative period; however, the amounts are being continually reduced as awareness of opioid abuse spreads. Here we seek to evaluate the effectiveness of a novel opiate-sparing protocol (OSP) for primary THAs in reducing opiate administrations, while maintaining similar levels of pain control and postoperative function. METHODS:All patients undergoing primary THA between January 1, 2019 and June 30, 2019 were placed under a novel OSP. Data were prospectively collected as part of standard of care. To assess the primary outcome of opiate consumption, nursing documented opiate administration events were converted into morphine milligram equivalences (MMEs) per patient encounter per 24-hour interval. Postoperative pain and functional status were assessed as secondary outcomes using the Verbal Rating Scale for pain and the Activity Measure for Post-Acute Care scores, respectively. RESULTS:One thousand fifty primary THAs had received our institution's OSP, and 953 patients were utilized as our historical control. OSP patients demonstrated significantly lower 0-24, 24-48, and 48-72 hours with less opiate administration variance (total MME: Control 75.55 ± 121.07 MME vs OSP 57.10 ± 87.48 MME; 24.42% decrease, P < .001). Although pain scores reached statistical significance between 0 and 12 (Control 2.09 vs OSP 2.36, P < .001), their differences were not clinically significant. Finally, OSP patients demonstrated a trend toward higher Activity Measure for Post-Acute Care scores across all 6 domains (total scores: Control 20.53 ± 3.67 vs OSP 20.76 ± 3.64, P = .18). CONCLUSION/CONCLUSIONS:Implementation of an OSP can significantly decrease the utilization of opioids in the immediate postoperative period. Inpatient opioid administration can be significantly reduced while maintaining a comparable and non-inferior level of pain and function.
PMID: 32139187
ISSN: 1532-8406
CID: 4339902
Comparison of Payment Margins Between the Bundled Payments for Care Improvement Initiative and the Comprehensive Care for Joint Replacement Model Shows a Marked Reduction for a Successful Program
Padilla, Jorge A; Gabor, Jonathan A; Kalkut, Gary E; Pazand, Lily; Zuckerman, Joseph D; Macaulay, William; Bosco, Joseph A; Slover, James D
BACKGROUND:The Comprehensive Care for Joint Replacement (CJR) model was implemented to address the 2 most commonly billed inpatient surgical procedures, total hip arthroplasty and total knee arthroplasty. The primary purpose of this study was to review the economic implications of 1 institution's mandatory involvement in the CJR in comparison with prior involvement in the Bundled Payments for Care Improvement (BPCI) initiative. METHODS:The mean cost per episode of care was calculated using our institution's historical data. The target prices, projected savings or losses per episode of care, and projected annual savings for both BPCI and CJR were established and were comparatively analyzed. RESULTS:The CJR target prices will decrease in comparison with BPCI target prices by 24.0% for Medicare Severity-Diagnosis Related Group (MS-DRG) 469 without fracture, 22.8% for MS-DRG 469 with fracture, 26.1% for MS-DRG 470 without fracture, and 27.7% for MS-DRG 470 with fracture, resulting in a reduction in savings per episode of care by 92.8% for MS-DRG 469 without fracture, 166.0% for MS-DRG 469 with fracture, 94.9% for MS-DRG 470 without fracture, and 61.7% for MS-DRG 470 with fracture. Our institution's projected annual savings under CJR will decrease by 83.3%. CONCLUSIONS:These results suggest that the margin for savings in the CJR will be substantially reduced compared with the margin for savings in the BPCI. In hospitals that had previously devoted resources, these will have far less impact in the CJR, and hospitals new to the CJR that have not made these investments previously will require even greater resources for developing cost reduction and quality control strategies to remain financially solvent. LEVEL OF EVIDENCE/METHODS:Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.
PMID: 31567678
ISSN: 1535-1386
CID: 4116002
Recurrent Hemarthrosis Following Total Knee Arthroplasty
Held, Michael B; Grosso, Matthew J; Sarpong, Nana O; Hamilton, William G; Sista, Akhilesh K; Macaulay, William
PMID: 31663920
ISSN: 2329-9185
CID: 4163302
Virtual Reality Simulation Facilitates Resident Training in Total Hip Arthroplasty: A Randomized Controlled Trial
Hooper, Jessica; Tsiridis, Eleftherios; Feng, James E; Schwarzkopf, Ran; Waren, Daniel; Long, William J; Poultsides, Lazaros; Macaulay, William
BACKGROUND:No study has yet assessed the efficacy of virtual reality (VR) simulation for teaching orthopedic surgery residents. In this blinded, randomized, and controlled trial, we asked if the use of VR simulation improved postgraduate year (PGY)-1 orthopedic residents' performance in cadaver total hip arthroplasty and if the use of VR simulation had a preferentially beneficial effect on specific aspects of surgical skills or knowledge. METHODS:Fourteen PGY-1 orthopedic residents completed a written pretest and a single cadaver total hip arthroplasty (THA) to establish baseline levels of knowledge and surgical ability before 7 were randomized to VR-THA simulation. All participants then completed a second cadaver THA and retook the test to assess for score improvements. The primary outcomes were improvement in test and cadaver THA scores. RESULTS:There was no significant difference in the improvement in test scores between the VR and control groups (P = .078). In multivariate regression analysis, the VR cohort demonstrated a significant improvement in overall cadaver THA scores (P = .048). The VR cohort demonstrated greater improvement in each specific score category compared with the control group, but this trend was only statistically significant for technical performance (P = .009). CONCLUSIONS:VR-simulation improves PGY-1 resident surgical skills but has no significant effect on medical knowledge. The most significant improvement was seen in technical skills. We anticipate that VR simulation will become an indispensable part of orthopedic surgical education, but further study is needed to determine how best to use VR simulation within a comprehensive curriculum. LEVEL OF EVIDENCE/METHODS:Level 1.
PMID: 31056442
ISSN: 1532-8406
CID: 4125112
Tramadol in Knee Osteoarthritis: Does Preoperative Use Affect Patient-Reported Outcomes After Total Knee Arthroplasty?
Driesman, Adam; Kaplan, Daniel; Feng, James E; Waren, Daniel P; Vigdorchik, Jonathan; Meere, Patrick; Fernandez-Madrid, Ivan; Slover, James; Macaulay, William
BACKGROUND:The 2013 American Academy of Orthopedic Surgeons evidence-based guidelines recommend against the use of preoperative narcotics in the management of symptomatic osteoarthritic knees; however, the guidelines strongly recommend tramadol in this patient population. To our knowledge, no study to date has evaluated outcomes in patients who use tramadol exclusively as compared with narcotics naive patients. METHODS:This is a retrospective study of prospectively collected data for patients who underwent unilateral primary total knee arthroplasty between January 2017 and March 2018. PRO scores were obtained using a novel electronic patient rehabilitation application, which pushed PRO surveys via email and mobile devices within 1 month prior to surgery and 3 months postoperatively. RESULTS:One hundred and thirty-six patients were opiate naïve, while 63 had obtained narcotics before the index operation. Of those, 21 patients received tramadol. The average preoperative Knee Disability and Osteoarthritis Outcome Scores were 50.4, 49.95, and 48.01 for the naïve, tramadol, and narcotic populations, respectively, (P = .60). The tramadol cohort had the least gain in 3 months postoperative Knee Disability and Osteoarthritis Outcome Scores, improving on average 12.5 points in comparison to the 19.1 and 20.1 improvements seen in the narcotic and naïve cohorts, respectively (P = .09). This difference was statistically significant when comparing the naïve and tramadol populations alone in post hoc analysis (P = .016). CONCLUSIONS:When comparing patients who took tramadol preoperatively to patients who were opiate naïve, patients that used tramadol trended toward significantly less improvement in functional outcomes in the short-term postoperative period.
PMID: 31076193
ISSN: 1532-8406
CID: 4002032
Cemented versus Cementless Stems in Revision Total Knee Arthroplasty
Driesman, Adam S; Macaulay, William; Schwarzkopf, Ran
Successful arthroplasty of the knee requires a stable foundation for implant placement, adequate mechanical alignment, and durable fixation. In the revision setting, the later may be difficult to obtain, especially in the setting of significant bone loss. While augments, cones, and sleeves have greatly enhanced the modern knee surgeon's ability to gain fixation in metaphyseal bone, stems continue to be a cornerstone tool in revision arthroplasty to bypass deficient or damaged bone surfaces to enhance structural stability of a revision construct. When placing a revision construct, there remains two options to assist with fixation, either fully cementing the entire implant or using a "hybrid" system, which combines an uncemented press-fit diaphyseal stem with cement in both the metaphysis and metaphysis-diaphysis junction of the keel. In this review, we discuss the history of these two techniques, evaluate the theoretical benefits and pitfalls, and assess the best evidence supporting each in the literature. To conclude, we will examine future directions and questions needed to better elucidate the best treatment options in a variety of revision scenarios.
PMID: 30736057
ISSN: 1938-2480
CID: 3632512
Modifying Patient Expectations Can Enhance Total Hip Arthroplasty Postoperative Satisfaction
Padilla, Jorge A; Feng, James E; Anoushiravani, Afshin A; Hozack, William J; Schwarzkopf, Ran; Macaulay, William B
BACKGROUND:A better understanding of patient expectations within the perioperative setting will enable clinicians to better tailor care to the needs of the total hip arthroplasty (THA) recipient. Such an approach will promote patient-centered decision-making and optimize recovery times while enhancing mandated hospital quality metrics. In the present study, we preoperatively and postoperatively surveyed THA candidates to elucidate the relationship between patient expectations and length of stay (LOS). METHODS:This is a multi-institutional prospective study among THA candidates. Patients were surveyed regarding discharge planning 1 week preoperatively and postoperatively to capture perioperative patient expectations and correlate with inpatient LOS. RESULTS:In total, 93 THAs performed by 6 high-volume orthopedic surgeons at 2 medical centers. Our results demonstrated that patients of male gender and commercial insurance had significantly (P < .05) shorter LOS. Shorter LOS patients demonstrated significantly higher levels of LOS acceptance ("very comfortable" rate in same-day discharge: 75.0% and next-day discharge: 63.8%; 2 days: 40.7%; 3+ days: 42.9%; P < .05) and a higher likelihood to participate in SDD programs. Postoperatively, patients with a shorter LOS had more acceptance to their LOS, albeit not statistically significant (PÂ = .20). CONCLUSION/CONCLUSIONS:Our results suggest that guiding patient expectations within the perioperative setting is an essential component for successful and timely discharge after THA. Having clear and transparent discussion with the surgical team regarding the perioperative course can improve a THA candidate's understanding and buy-in with the postoperative plan, regardless of LOS. Finally, inpatient LOS does not appear to affect patient satisfaction. LEVEL OF EVIDENCE/METHODS:Level II, prospective observational study.
PMID: 30795937
ISSN: 1532-8406
CID: 3688092
Payer type does not impact patient-reported outcomes after primary total knee arthroplasty
Feng, James E; Gabor, Jonathan A; Anoushiravani, Afshin A; Long, William J; Vigdorchik, Jonathan M; Meere, Patrick A; Iorio, Richard; Schwarzkopf, Ran; Macaulay, William
Background/UNASSIGNED:There is a paucity of literature assessing whether payer type has an impact on postoperative patient-reported outcomes (PROs) after total knee arthroplasty (TKA). The aim of this study was to comparatively evaluate TKA PROs among patients with commercial and Medicare insurance. Methods/UNASSIGNED:We conducted a single-center, retrospective review of patients operated between January 2017 and March 2018. Knee Disability and Osteoarthritis Outcome Score Junior (KOOS-Jr) and Veterans RAND 12 Health Survey (VR-12) Physical Component (VR-12 PCS) and Mental Component (VR-12 MCS) PRO scores were collected prospectively at baseline and 12 weeks postoperatively via an electronic patient rehabilitation application. Univariable and multivariable linear regressions were utilized to assess the effects of patient insurance type on PRO. Results/UNASSIGNED:> .05). Conclusions/UNASSIGNED:After adjusting for patient-specific variables, PROs are similar at baseline and 12 weeks postoperatively between commercial and Medicare cohorts. For TKA candidates with similar baseline demographics, surgeons can expect similar perioperative PROs regardless of insurance type.
PMCID:6470348
PMID: 31020034
ISSN: 2352-3441
CID: 3821722
Multi-system manifestion of cobalt toxicity in the setting of metal-on-polyethylene total hip arthroplasty [Meeting Abstract]
Grosso, M; Park, P; Macaulay, W
Case Study: Objectives: Cobalt toxicity in the setting of total hip arthroplasty is a rare and striking condition, which can lead to significant hip and systemic issues. The purpose of this case report is to describe the constellation of symptoms and importance of addressing the problem of cobalt toxicity in the operating room in a timely manner. Methods: We retrospectively reviewed the chart of a 66 year old male who underwent left total hip arthroplasty with ceramic femoral head four years prior which was subsequently revised to a cobalt chromium head on polyethylene line one year prior to presentation due to ceramic liner failure, who presented with cobalt toxicity. Results: The patient presented with progressive loss of vision and colour vision, balance issues, lower extremity swelling, cold intolerance, and progressive hearing loss with tinnitus. Blood cobalt chromium level revealed elevation to 1076 ug/L (normal < 0.5 ug/L). Intraoperatively, grey milky fluid was found consistent with diffuse metallosis. Approximately 10-15 shards of ceramic particles, ranging in size from 1-9 mm in length, were found in the periarticular area. The damaged polyethylene liner and cobalt chromium head were replaced and a ceramic head was implanted. The patient did well postoperatively. By 7 months postoperatively hearing and vision had almost completely returned to baseline. Conclusion: Cobalt toxicity from local adverse tissue reactions in the setting of metal femoral heads is exceedingly rare. As seen in our patient presented here, early recognition using serum cobalt levels and a multi-disciplinary approach can lead to timely identification of cobalt toxicity and increase the chances of full recovery with prompt revision surgery and close follow-up
EMBASE:624286815
ISSN: 1120-7000
CID: 3370802
Opioids vs Nonopioids for Chronic Back, Hip, or Knee Pain
Wang, Wenbao; Macaulay, William
PMID: 30088003
ISSN: 1538-3598
CID: 3226202