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Symptomatic central venous stenosis in a hemodialysis patient leading to loss of arteriovenous access: a case report and literature review

Tatapudi, Vasishta S; Spinowitz, Noam; Goldfarb, David S
Central venous stenosis is a well-described sequel to the placement of hemodialysis catheters in the central venous system. The presence of an ipsilateral arteriovenous fistula or graft often leads to severe venous dilatation, arm edema and recurrent infections. Vascular access thrombosis, compromised blood flow and inadequate dialysis delivery are dreaded complications that eventually render the access unusable. We report the case of a 58-year-old male hemodialysis patient who developed symptomatic central venous stenosis to illustrate the problem and review the pertinent literature. This patient developed severe enlargement of upper extremity veins due to central venous stenosis. The symptoms were refractory to multiple endovascular interventions and eventually necessitated ligation of his arteriovenous fistula. Central venous stenosis remains a pervasive problem despite advances in our understanding of its etiology and recognition of the enormity of its consequences. Due to the lack of effective therapeutic options, prevention is better than cure.
PMCID:3999441
PMID: 24803921
ISSN: 1664-5529
CID: 970272

Megakaryocyte morphometry in chronic myeloid leukaemia and thrombocytopenic purpura

Tatapudi, Surya Vasishta; Basu, Debdatta
ORIGINAL:0012419
ISSN: 0970-938x
CID: 2905052