Faculty Bibliography

Cerebral spinal fluid (CSF) pulse waveform basing on 899 records was classified. Eleven types of CSF pulse waveform were further classified according to the harmonic wave relation and the configuration of the pulse waveform. The characteristic features of various types of CSF pulse waveform were considered to reflect certain intracranial pathophysiological conditions including cerebral compliance, cerebral vasomotor reactivity and intracranial elastance.

The results of the Be-induced leukocyte migration inhibition test (Be-MIT), the lymphocyte transformation test (LI), the E-rosette formation test (E-RFC), the old tuberculin test (OT), and sero-immunoglobulin (IgG, IgA, IgM) measurements on 13 cases of berylliosis, 44 members of the observation group, and 51 members of the contact group are reported. In the Be-MIT, 2 of the berylliosis patients were new cases that had been diagnosed and treated for a long time, and both tested positive (18%). Fourteen patients from the observation group tested positive (32%), and 15 from the contact group tested positive (30%). The 8 cases in the control group tested negative; 7 patients from the observation group and 3 of the berylliosis cases tested negative after being treated. The lymphocyte transformation rates of the observation group and the berylliosis group were significantly lower than that of the control group (P less than 0.01). Both Et-RFC and Ea-RFC contents in the group with berylliosis were much lower than those in the control group (P less than 0.01). OT tests were performed on 8 berylliosis patients and 10 healthy men. Seven patients showed negative reactions and one showed a positive reaction. All the healthy men showed positive reactions. The IgG and IgA levels of the observation group were significantly higher than those of the control group (P less than 0.01). The Be-MIT could detect active beryllium disease at an early stage as well as Be-sensitive individuals. This test could be used as a supplementary diagnostic index for the differential diagnosis of berylliosis and for the evaluation of a curative effect.

beta-endorphin-like immunoreactivity (beta-ELI) was measured in cerebrospinal fluid (CSF) of 36 acute head-injured patients and 12 patients without head injury as controls. The mean level of beta-ELI in CSF of controls, mild cerebral contusions, and severe cerebral contusion patients were 51.9 +/- 5.6 pg/ml, 110.5 +/- 14.5 pg/ml, and 173.8 +/- 20.1 pg/ml respectively, with significant difference between them. The results also showed that beta-ELI may reflect the prognosis of acute head-injured patients.