Faculty Bibliography

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616

Neurology. 2002:58(8 Suppl 4):S32-9.DOI: 10.1212/wnl.58.8_suppl_4.s32

Symptomatic therapy for underrecognized manifestations of multiple sclerosis

Krupp, Lauren B; Rizvi, Syed A
The symptoms that affect individuals with MS are diverse and change over time. Addressing symptoms in a multidisciplinary fashion and helping patients address problems as they occur are the major elements of symptom management. Successful management involves treating not only the more readily recognized manifestations of MS but also the less apparent MS features, including fatigue, cognitive loss, mood disturbance, and pain. Management of these symptoms is reviewed.
PMID: 11971124
ISSN: 0028-3878
CID: 1682832
Neurology. 2002:58(7):A405-A405.DOI:

A randomized, double-masked clinical trial studying the treatment of post-Lyme disease [Meeting Abstract]

Krupp, LB; Hyman, LG; Grimson, R; Coyle, PK; Melville, P; Ahnn, S; Dattwyler, R; Chandler, B; Kornheiser, L
ISI:000174875901023
ISSN: 0028-3878
CID: 2233182
Annals of neurology. 2002:52(3):S87-S87.DOI:

The use of inteferon-beta-1a (Avonex) and modafinil to evaluate and treat cytokine-induced fatigue in multiple sclerosis [Meeting Abstract]

Krupp, LB; Christodoulou, C; Madigan, D; Morgan, T; Scherl, WF; Melville, P; McIlree, C
ISI:000177900500275
ISSN: 0364-5134
CID: 2233422
Annals of neurology. 2002:52(3):S118-S118.DOI:

Preliminary report from the pediatric multiple sclerosis study group [Meeting Abstract]

Belman, AL; Krupp, L; Cianciulli, C; Milazzo, M; Preston, T; Christodoulou, C; Morgan, T; MacAllister, W; Novak, G; Mattis, P; Blitz, K; Wilson, B; Panasci, D; Banwell, B; Anderson, P; Weinstock-Guttman, B; Benedict, R; Rommohan, K; Lynn, DJ
ISI:000177900500338
ISSN: 0364-5134
CID: 2233592
Multiple sclerosis. 2006:12(Suppl 1).DOI:

Consensus definitions of acquired demyelinating disorders of childhood [Meeting Abstract]

Krupp, Lauren; Tenembaum, S; Banwell, B; International Pediatric MS Study Group
ORIGINAL:0011445
ISSN: 1352-4585
CID: 2238312
Multiple sclerosis. 2002:8(Suppl).DOI:

Clinical, demographic and cognitive features of childhood onset multiple sclerosis [Meeting Abstract]

Krupp, Lauren B; Belman, Anita; Cianciulli, C; Milazzo, M; Blitz, K; Morgan, T; Melville, P
ORIGINAL:0011444
ISSN: 1352-4585
CID: 2238302
Multiple sclerosis. 2002:8(Suppl).DOI:

Cognitive screening in MS patients recruited for a clinical trial [Meeting Abstract]

Christodoulou, C; Krupp, Lauren B; Melville, P; Scherl, W; Morgan, T; McIlree, C
ORIGINAL:0011443
ISSN: 1352-4585
CID: 2238292
Current neurology & neuroscience reports. 2001:1(3):294-8.DOI: 10.1007/s11910-001-0033-7

Fatigue in multiple sclerosis

Krupp, L B; Christodoulou, C
Fatigue is among the most common, yet least understood, symptoms of multiple sclerosis (MS) [1.]. It can profoundly disrupt the occupational and social functioning of patients, and is recognized as a criterion for MS disability by the Social Security Administration. Most approaches to fatigue assessment can be classified as either self-report scales or performance-based measures of motor or cognitive output. During the clinical management of fatigue, it is important to consider the role of other MS symptoms on fatigue, as well as that of non-MS-related medical conditions. Management of fatigue in MS often entails both pharmacologic and behavioral components. This article reviews recent developments in the assessment, treatment, and pathogenesis of MS fatigue.
PMID: 11898532
ISSN: 1528-4042
CID: 1682842
Applied neuropsychology. 2001:8(3):155-60.DOI: 10.1207/S15324826AN0803_4

Cognitive dysfunction lateralizes with NAA in multiple sclerosis

Pan, J W; Krupp, L B; Elkins, L E; Coyle, P K
Recent studies have demonstrated the utility of magnetic resonance (MR) spectroscopic imaging to evaluate axonal integrity in patients with multiple sclerosis (MS). Patient status in MS is frequently assessed by the Expanded Disability Status Scale, which emphasizes ambulation but underestimates the contribution of cognitive factors. Yet, cognitive functions of memory and processing are known to be impaired in MS. We used quantitative MR spectroscopy to determine this relation between cognitive function and N-acetyl aspartate (NAA) levels. We find a significant correlation (r = .63, p < .005) for the left periventricular (PV) NAA concentrations with performance on the verbal Selective Reminding Test. Right PVNAA was significantly (p < .02) correlated with the Tower of Hanoi performance, with r = .58.
PMID: 11686650
ISSN: 0908-4282
CID: 1682852
Neurology. 2001:56(8):A479-A480.DOI:

Diagnostic accuracy of serologic testing for Lyme disease [Meeting Abstract]

Beitinjaneh, F; Rizvi, SA; Coyle, PK; Krupp, LB
ISI:000168270601264
ISSN: 0028-3878
CID: 2233172