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Can We Tell if the Syndesmosis is Reduced Using Fluoroscopy?

Koenig, Scott J; Tornetta, Paul 3rd; Merlin, Gabriel; Bodgan, Yelena; Egol, Kenneth A; Ostrum, Robert F; Wolinsky, Philip R
OBJECTIVE:: To evaluate the ability of surgeons to determine if the fibula is reduced in the sagittal plane in relation to the tibia based upon fluoroscopic images by comparison with the known normal for both the ipsilateral and contralateral ankles. METHODS:: Perfect lateral radiographs of both ankles were obtained in seven cadaveric specimens. The fibula was translated 2.5mm and 5mm in the anterior and posterior directions. Four orthopedic trauma-trained surgeons were presented with a fictitious case consisting of a "normal" image, followed by 10 randomly selected images from both ankles, and were asked to determine if the fibula was reduced, or displaced anteriorly or posteriorly. The ability of the surgeons to identify displacement and inter-observer reliability were assessed. RESULTS:: The surgeons were better able to identify malreduction than reduction (NPV 95% ipsilateral, 85% contralateral). The overall sensitivity for reduction was 94% for the ipsilateral ankle, but only 68% for the contralateral ankle. Anterior displacement and greater magnitudes of displacement were most easily diagnosed. All reviewers had the most difficulty with 2.5mm of posterior displacement. The intraobserver agreement was excellent for anterior displacement and 5mm of displacement in either direction (kappa .71/.75). Surgeons who routinely used the contralateral lateral radiograph were more accurate. CONCLUSIONS:: While it is unknown how much translational displacement of the syndesmosis is acceptable, it seems that the experienced surgeon will be able to reduce the joint within 2.5mm and that fluoroscopic comparisons to the normal ankle are helpful in determining malreduction.
PMID: 25635357
ISSN: 0890-5339
CID: 1447982

A Biomechanical Study of Posteromedial Tibial Plateau Fracture Stability: Do They All Require Fixation?

Cuellar, Vanessa G; Martinez, Danny; Immerman, Igor; Oh, Cheongeun; Walker, Peter S; Egol, Kenneth A
OBJECTIVES: While the posteromedial fragment in tibial plateau fractures is often considered unstable, biomechanical evidence supporting this view is lacking. We aimed to evaluate the stability of the fragment in a cadaver model. Our hypothesis was that under the expected small axial force during rehabilitation and the combined effects of this force with shear force, internal rotation torque and varus moment, the most common posteromedial tibia fragment morphology could maintain stability in early flexion. METHODS: Axial compression force alone or combined with either posterior shear, internal rotation torque, or varus moment was applied to the femurs of five fresh cadaveric knees. A Tekscan pressure mapping system was used to measure pressure and contact area between the femoral condyles, meniscus, and tibial plateau. A Microscribe 3D digitizer was used to define the three-dimensional positions of the femur and tibia. A 10 mm and then a 20 mm osteotomy was created with a saw at an angle of 30 degrees in the axial plane with respect to the tangent of the posterior tibial plateau and 75 degrees in the sagittal plane, representing a typical posteromedial fracture fragment. At each flexion angle (15 degrees , 30 degrees , 60 degrees , 90 degrees , 120 degrees ) and loading condition (axial compression only, compression with shear force, torque, and varus moment), distal displacement of the medial femoral condyle as well as the tibial fracture fragments, were determined. RESULTS: For the 10 mm fragment, medial femoral condyle displacement was little affected up to approximately 30 degrees flexion, after which it increased. For the 20 mm fragment, there was progressive medial femoral condyle displacement with increasing flexion from baseline. However, for the 10mm and 20mm fragments themselves, displacements were noted at every flexion angle, starting at 1.7mm inferior displacement with 15 degrees of flexion and internal rotation torque and up to 10.2mm displacement with 90 degrees flexion and varus bending moment. CONCLUSIONS: In this cadaveric model of a posteromedial tibial plateau fracture, both fracture fragments studied displaced with knee flexion, even at low flexion angles. While such fragments may initially appear non-displaced after injury, posteromedial fragments similar to these tested are likely to displace during knee range of motion exercises in non-weight bearing conditions.
PMID: 25591035
ISSN: 0890-5339
CID: 1436422

Measurement reproducibility of magnetic resonance imaging-based finite element analysis of proximal femur microarchitecture for in vivo assessment of bone strength

Chang, Gregory; Hotca-Cho, Alexandra; Rusinek, Henry; Honig, Stephen; Mikheev, Artem; Egol, Kenneth; Regatte, Ravinder R; Rajapakse, Chamith S
INTRODUCTION: Osteoporosis is a disease of weak bone. Our goal was to determine the measurement reproducibility of magnetic resonance assessment of proximal femur strength. METHODS: This study had institutional review board approval, and written informed consent was obtained from all subjects. We obtained images of proximal femur microarchitecture by scanning 12 subjects three times within 1 week at 3T using a high-resolution 3-D FLASH sequence. We applied finite element analysis to compute proximal femur stiffness and femoral neck elastic modulus. RESULTS: Within-day and between-day root-mean-square coefficients of variation and intraclass correlation coefficients ranged from 3.5 to 6.6 % and 0.96 to 0.98, respectively. CONCLUSION: The measurement reproducibility of magnetic resonance assessment of proximal femur strength is suitable for clinical studies of disease progression or treatment response related to osteoporosis bone-strengthening interventions.
PMCID:4605426
PMID: 25487834
ISSN: 0968-5243
CID: 1393492

Displaced Intra-Articular Fractures Involving the Volar Rim of the Distal Radius

Marcano, Alejandro; Taormina, David P; Karia, Raj; Paksima, Nader; Posner, Martin; Egol, Kenneth A
PURPOSE: To describe the features of displaced intra-articular fractures confined to the volar rim of the distal radius and compare outcomes after their operative fixation to complete intra-articular and extra-articular fractures treated with operative fixation. METHODS: A total of 627 distal radius fractures were treated over a 6-year period. Twenty-eight patients had volar rim fractures (type 23-B3, as classified by the Orthopaedic Trauma Association [OTA]), all treated with operative reduction and fixation using a volar buttress plate. Clinical outcome information including radiographs, Short Form-36 health survey, and Disabilities of the Arm, Shoulder, and Hand questionnaire were collected at regular postoperative intervals. Patients with volar rim fractures were compared with patients who sustained other types of operatively managed distal radius fractures (OTA types 23-A, 23-B1/B2, and 23-C). RESULTS: The most common type of volar rim fracture consisted of a single large fragment (OTA 23-B3.2; 46%), followed by comminuted fractures (OTA 23-B3.3; 36%). Restoration of radiographic parameters was similar between groups except for an increased volar tilt in volar rim fractures compared with group 23-B1/B2. Active wrist and finger motion improved in all groups except for wrist extension, which was less in the 23-B1/B2 groups. The 23-B1/B2 group had the greatest pain and worst Short Form-36 scores. Disabilities of the Arm, Shoulder, and Hand questionnaire scores were similar and without differences between groups. CONCLUSIONS: Our data suggest that patients with volar rim distal radius fractures can expect a rapid return to function with minimal risk for complications and have outcomes similar to other types of operatively treated distal radius fractures. Further investigation of type 23-B fractures (23-B1/B2) is warranted owing to evidence of diminished outcomes. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III.
PMID: 25446998
ISSN: 0363-5023
CID: 1370352

Development of Compartment Syndrome Negatively Impacts Length of Stay and Cost Following Tibia Fracture

Crespo, Alexander M; Manoli, Arthur 3rd; Konda, Sanjit R; Egol, Kenneth A
OBJECTIVES:: To quantify the impact of compartment syndrome in the setting of tibial shaft fracture on hospital length of stay and total hospital charges. DESIGN:: Retrospective case-control study. SETTING:: All New York State hospital admissions from 2001-2011, as recorded by the New York Statewide Planning and Research Cooperative System (SPARCS) database. PATIENTS:: 33,629 inpatients with isolated open or closed fractures of the tibia and/or fibula (AO/OTA 41-43). 692 patients developed a compartment syndrome in the setting of tibia fracture. All patients were filtered to ensure none had other complications or medical comorbidities that would increase length of stay or total hospital charges. INTERVENTION:: Fasciotomy and delayed closure in patients who developed a compartment syndrome. MAIN OUTCOME MEASURE:: Hospital length of stay (days) and total inflation-adjusted hospital charges RESULTS:: A total of 33,629 patients with tibial shaft fracture were included in the study. There were 32,937 patients who did not develop a compartment syndrome. For this group, the mean length of stay was 6 days and the mean inflation-adjusted hospital charges were $34,000. Patients who developed compartment syndrome remained in-house for an average of 14 days with average charges totaling $79,000. These differences were highly significant for both lengths of stay and hospital charges (p < 0.001). CONCLUSION:: Besides the obvious physical detriment experienced by patients with compartment syndrome, there is also a significant economic impact to the healthcare system. Compartment syndrome following a tibial fracture more than doubles length of stay and total hospital charges. These findings highlight the need for a standardized care algorithm aimed towards efficiently and adequately treating acute compartment syndrome. Such an algorithm would optimize cost of care and presumably decrease length of stay. LEVEL OF EVIDENCE:: Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.
PMID: 25463427
ISSN: 0890-5339
CID: 1370892

Do orthopaedic fracture skills courses improve resident performance?

Egol, Kenneth A; Phillips, Donna; Vongbandith, Tom; Szyld, Demian; Strauss, Eric J
INTRODUCTION: We hypothesized that resident participation in a hands-on fracture fixation course leads to significant improvement in their performance as assessed in a simulated fracture fixation model. METHODS: Twenty-three junior orthopaedic surgery residents were tasked to treat radial shaft fractures with standard fixation techniques in a sawbones fracture fixation simulation twice during the year. Before the first simulation, 6 of the residents participated in a fraction fixation skills course. The simulation repeated 6 months later after all residents attended the course. Residents also completed a 15-question written examination. Assessment included evaluation of each step of the procedure, a score based on the objective structured assessment of technical skill (OSATS) system, and grade on the examination. Comparisons were made between the two cohorts and the two testing time points. RESULTS: Significant improvements were present in the percentage of tasks completed correctly (64.1% vs 84.3%) the overall OSATS score (13.8 vs 17.1) and examination correct answers (8.6 vs 12.5) for the overall cohort between the two testing time points (p<0.001, p<0.03, p<0.04 respectively). Residents who had not participated in the surgical skills course at the time of their initial simulation demonstrated significant improvements in percentage of tasks completed correctly (61.3% vs 81.2%) and OSATS score (12.4 vs 17.0) (p<0.002, p<0.01 respectively). No significant difference was noted in performance for the cohort who had already participated in the course (p=0.87 and p=0.68). The cohort that had taken the course prior to the initial simulation showed significantly higher scores at initial evaluation (88.5% vs 58.5% percentage of tasks completed correctly, 17.3 vs 12.0 OSATS score, 12.5 vs 8.6 correct answers on the examination). At the second simulation, no significant difference was seen with task completion or examination grade, but a significant difference still existed with respect to the OSATS score (20.0 vs 17.0; p<0.03). CONCLUSION: Participation in a formal surgical skills course significantly improved practical operative skills as assessed by the simulation. The benefits of the course were maintained to 6 months with residents who completed the training earlier continuing to demonstrate an advantage in skills. Such courses are a valuable training resource which directly impact resident performance.
PMID: 25476015
ISSN: 0020-1383
CID: 1371212

7 Tesla MRI of bone microarchitecture discriminates between women without and with fragility fractures who do not differ by bone mineral density

Chang, Gregory; Honig, Stephen; Liu, Yinxiao; Chen, Cheng; Chu, Kevin K; Rajapakse, Chamith S; Egol, Kenneth; Xia, Ding; Saha, Punam K; Regatte, Ravinder R
Osteoporosis is a disease of poor bone quality. Bone mineral density (BMD) has limited ability to discriminate between subjects without and with poor bone quality, and assessment of bone microarchitecture may have added value in this regard. Our goals were to use 7 T MRI to: (1) quantify and compare distal femur bone microarchitecture in women without and with poor bone quality (defined clinically by presence of fragility fractures); and (2) determine whether microarchitectural parameters could be used to discriminate between these two groups. This study had institutional review board approval, and we obtained written informed consent from all subjects. We used a 28-channel knee coil to image the distal femur of 31 subjects with fragility fractures and 25 controls without fracture on a 7 T MRI scanner using a 3-D fast low angle shot sequence (0.234 mm x 0.234 mm x 1 mm, parallel imaging factor = 2, acquisition time = 7 min 9 s). We applied digital topological analysis to quantify parameters of bone microarchitecture. All subjects also underwent standard clinical BMD assessment in the hip and spine. Compared to controls, fracture cases demonstrated lower bone volume fraction and markers of trabecular number, plate-like structure, and plate-to-rod ratio, and higher markers of trabecular isolation, rod disruption, and network resorption (p < 0.05 for all). There were no differences in hip or spine BMD T-scores between groups (p > 0.05). In receiver-operating-characteristics analyses, microarchitectural parameters could discriminate cases and controls (AUC = 0.66-0.73, p < 0.05). Hip and spine BMD T-scores could not discriminate cases and controls (AUC = 0.58-0.64, p >/= 0.08). We conclude that 7 T MRI can detect bone microarchitectural deterioration in women with fragility fractures who do not differ by BMD. Microarchitectural parameters might some day be used as an additional tool to detect patients with poor bone quality who cannot be detected by dual-energy X-ray absorptiometry (DXA).
PMCID:4363287
PMID: 24752823
ISSN: 0914-8779
CID: 1320282

Fibulectomy, Tibial Shortening, and Ankle Arthrodesis as an Alternative Treatment of Nonhealing Wounds Following Open Ankle Fracture in Compromised Elderly Adults

Crespo, Alexander M; Rautenberg, Alyssa F; Siev, Noam; Saadeh, Pierre; Egol, Kenneth A
PMID: 25201329
ISSN: 1071-1007
CID: 1181432

Sleep Disturbance Following Fracture is Related to Emotional Well Being Rather than Functional Result

Shulman, Brandon S; Liporace, Frank A; Davidovitch, Roy I; Karia, Raj; Egol, Kenneth A
OBJECTIVES:: The aim of our study was to investigate the rate, longitudinal improvement, and risk factors of sleep disturbance following four common orthopaedic traumatic conditions. METHODS:: The functional status of 1,095 patients was prospectively assessed using validated questionnaires for patients with acute proximal humerus (n=111), distal radius (n=440), tibial plateau (n=109), and ankle fractures (n=435). Patient reported sleep difficulty was compared to the overall functional and emotional status of each patient at three, six, and twelve months post-treatment. RESULTS:: Sleep difficulty at three months follow-up was reported in 41% of proximal humerus fracture patients, 25% of distal radius fracture patients, 36% of tibial plateau patients, and 19% of ankle fracture patients. By twelve months follow-up less than 20% of patients with all fracture types reported sleep difficulty. At twelve months follow-up the SF-36 Mental Health category for patients with distal radius fractures (p=0.001) and the Short Musculoskeletal Function Assessment (SMFA) Emotional category for patients with tibial plateau fractures (p=0.024) and ankle fractures (p=<0.001) were independent predictors of poor sleep while the respective functional status categories were not. CONCLUSIONS:: At twelve months follow-up, poor sleep was independently associated with poor emotional status, but not associated with poor functional status. The mental health status of patients with sleep difficulty in the latter stages of fracture healing should be carefully assessed in order to provide the highest level of care. The results of this study should allow orthopaedic trauma surgeons to counsel patients regarding expectations of difficulty sleeping following acute fractures. LEVEL OF EVIDENCE:: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
PMID: 25072285
ISSN: 0890-5339
CID: 1090052

Minimally Displaced Radial Head/Neck Fractures (Mason Type-I, OTA Types 21A2.2 and 21B2.1): Are We "Over Treating" Our Patients?

Shulman, Brandon S; Lee, James H; Liporace, Frank; Egol, Kenneth A
OBJECTIVE:: The purpose of this study was to investigate the nonoperative treatment strategies for Mason-Johnson Type-I radial head fractures. DESIGN AND SETTING:: Retrospective review of every patient with a closed radial head/neck fracture who presented to our tertiary care specialty institution in the past two years.Patients/Participants: A search of ICD-9 code 813.05, closed fracture of the radial head/neck, in our electronic record system yielded 82 consecutive patients. MAIN OUTCOME MEASUREMENTS:: Complications and treatment interventions were recorded. Demographic, radiographic, and physical exam data were collected for all patients treated nonoperatively and analyzed for association with recommendation for continued follow-up and radiographic assessment. RESULTS:: 54 patients (68%) had 56 nondisplaced or minimally displaced (< 2mm) radial head or neck fractures without additional injury to the affected limb. All patients were treated nonoperatively and no patients in this cohort developed a complication or had any medical or surgical intervention other than physical therapy. No radiographic or physical exam measure was significantly associated with recommendation for a second outpatient follow-up, third outpatient follow-up, or with the number of additional radiographs ordered beyond the initial exam. An average of 4.4 (SD 3.3) additional x-rays were taken of each affected elbow after initial outpatient presentation. CONCLUSIONS:: Orthopaedic surgeons are likely over treating patients with Mason-Johnson Type-I radial head fractures by recommending frequent radiographic follow-up without modifying treatment, leading to unnecessary patient visits, radiation exposure, and increased costs. LEVEL OF EVIDENCE:: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
PMID: 24978945
ISSN: 0890-5339
CID: 1065632