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Total Hip Arthroplasty for Posttraumatic Osteoarthritis of the Hip Fares Worse Than THA for Primary Osteoarthritis

Khurana, Sonya; Nobel, Tamar B; Merkow, Justin S; Walsh, Michael; Egol, Kenneth A
We conducted a study to evaluate differences between patients who had total hip arthroplasty (THA) for posttraumatic osteoarthritis (OA) and patients who had THA for primary OA. Using a prospective database, we followed 3844 patients who had THA for OA. Those who had THA for secondary causes of hip OA, developmental hip dysplasia, or inflammatory processes were excluded. Of the remaining 1199 patients, 62 (63 fractures) had THA for posttraumatic OA after previous acetabular or proximal femur fracture fixation, and 1137 had THA for primary OA and served as the control group. In the posttraumatic OA group, mean time between fracture repair and conversion to THA was 74 months. Compared with the control patients, the posttrauma patients lost more blood, were transfused more units of blood, had longer operating room times, and had more complications (all Ps < .001). Posttrauma patients had a mean follow-up of 4.44 years and a mean postoperative modified Harris Hip Score of 81.3 at latest follow-up. Of these patients, 12.5% required revision a mean of 3.5 years after initial arthroplasty. THA in patients with posttraumatic hip OA after an acetabular or proximal femur fracture is a longer and more complicated procedure with a higher rate of early failure.
PMID: 26161760
ISSN: 1934-3418
CID: 1669792

Definitive Fixation of Tibial Plateau Fractures

Yoon, Richard S; Liporace, Frank A; Egol, Kenneth A
Tibial plateau fractures present in a wide spectrum of injury severity and pattern, each requiring a different approach and strategy to achieve good clinical outcomes. Achieving those outcomes starts with a thorough evaluation and preoperative planning period, which leads to choosing the most appropriate surgical approach and fixation strategy. Through a case-based approach, this article presents the necessary pearls, techniques, and strategies to maximize outcomes and minimize complications for some of the more commonly presenting plateau fracture patterns.
PMID: 26043050
ISSN: 1558-1373
CID: 1615712

Supination external rotation ankle fractures: A simpler pattern with better outcomes

Tejwani, Nirmal C; Park, Ji Hae; Egol, Kenneth A
BACKGROUND: Rotational injuries are the most common and usually classified as per the Lauge Hansen classification; with the most common subgroup being the supination external rotation (SER) mechanism. Isolated fractures of the distal fibula (SE2) without associated ligamentous injury are usually treated with a splint or brace and the patient may be allowed to weight bear as tolerated. This study reports the functional outcomes following a stable, low energy, rotational ankle fracture supination external rotation (SER2) when compared to unstable SER4 fractures treated operatively. MATERIALS AND METHODS: 64 patients who were diagnosed and treated nonoperatively for a stable SER2 ankle fracture were followed prospectively. In the comparison group, 93 operatively treated fibular fractures were extracted from a prospectively collected database and evaluated comparison. Baseline characteristics obtained by trained interviewers at the time of injury included: Patient demographics, short form-36, short musculoskeletal functional assessment (SMFA) and American Orthopedic Foot and Ankle Society (AOFAS) questionnaires. Patients were followed at 3, 6 and 12 months postsurgery. Additional information obtained at each followup point included any complications or evidence on fracture healing. Data were analyzed by the Student's t-test and theFisher's Exact Test to compare demographic and functional outcomes between the two cohorts. P < 0.05 was considered to be significant. RESULTS: The average of patients' age in the stable fracture cohort was 43 versus 45 in the SER4 group. Nearly 64% of the patient population was female when compared with 37% in the operative group. In the SER2 by 6 months all patients had returned to baseline functional status. There were 18 delayed unions (all healed by 6 months). Based on the functional outcome scores all patients had returned to preoperative level. In comparison, SE4 patients had less functional recovery at 3 and 6 months (P < 0.05) based on the SMFA scores and at 3, 6 and 12 months based on the AOFAS (P < 0.001) scores. There was no difference in pain levels between the two groups at all time points. There were three nonunions in the SE4 group and six delayed unions. CONCLUSIONS: An SER2 ankle fracture is a relatively benign injury with functional limitations resolving by 3 months while the need for surgical fixation in SER ankle fractures appears to affect lower extremity function to a greater degree for a longer time period. Patients should be counseled as to these expected outcomes.
PMCID:4436489
PMID: 26015612
ISSN: 0019-5413
CID: 1602992

Uses of Negative Pressure Wound Therapy in Orthopedic Trauma

Gage, Mark J; Yoon, Richard S; Egol, Kenneth A; Liporace, Frank A
Negative pressure wound therapy (NPWT) is a useful management tool in the treatment of traumatic wounds and high-risk incisions after surgery. Since its development nearly 2 decades ago, uses and indications of NPWT have expanded, allowing its use in a variety of clinical scenarios. In addition to providing a brief summary on its mechanism of action, this article provides a focused, algorithmic approach on the use of NPWT by reviewing the available data, the appropriate clinical scenarios and indications, and the specific strategies that can be used to maximize outcomes.
PMID: 25771317
ISSN: 0030-5898
CID: 1505712

Delay in hip fracture surgery: an analysis of patient- and hospital-specific risk factors

Ryan, Devon J; Yoshihara, Hiroyuki; Yoneoka, Daisuke; Egol, Kenneth A; Zuckerman, Joseph D
OBJECTIVES:: To empirically define a "delay" for hip fracture surgery based on clinical outcomes, and to identify patient demographics and hospital factors contributing to surgical delay. DESIGN:: Retrospective database analysis. SETTING:: Hospital discharge data. PATIENTS/PARTICIPANTS:: A total of 2,121,215 patients undergoing surgical repair of hip fracture in the National Inpatient Sample (NIS) between 2000 and 2009. INTERVENTION:: Internal fixation or partial/total hip replacement. MAIN OUTCOME MEASUREMENTS:: Logistic regressions were performed to assess the effect of surgical timing on in-hospital complication and mortality rates, controlling for patient characteristics and hospital attributes. Subsequent regressions were performed to analyze which patient characteristics (age, gender, race, comorbidity burden, insurance status, and day of admission) and hospital factors (size, teaching status, and region) independently contributed to the likelihood of surgical delay. RESULTS:: Compared to same-day surgery, each additional day of delay was associated with a significantly higher overall complication rate. However, next-day surgery was not associated with an increased risk of in-hospital mortality. Surgery 2 calendar days (OR: 1.13) and 3+ days (OR: 1.33) following admission was associated with higher mortality rates. Based on these findings, "delay" was defined as surgery performed two or more days after admission. Significant factors related to surgical delay included comorbidity score, race, insurance status, hospital region, and day of admission. CONCLUSIONS:: Surgical delay in hip fracture care contributes to patient morbidity and mortality. A variety of patient and hospital characteristics seem to contribute to surgical delay, and point to important health care disparities. LEVEL OF EVIDENCE:: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
PMID: 25714442
ISSN: 0890-5339
CID: 1473882

Can We Tell if the Syndesmosis is Reduced Using Fluoroscopy?

Koenig, Scott J; Tornetta, Paul 3rd; Merlin, Gabriel; Bodgan, Yelena; Egol, Kenneth A; Ostrum, Robert F; Wolinsky, Philip R
OBJECTIVE:: To evaluate the ability of surgeons to determine if the fibula is reduced in the sagittal plane in relation to the tibia based upon fluoroscopic images by comparison with the known normal for both the ipsilateral and contralateral ankles. METHODS:: Perfect lateral radiographs of both ankles were obtained in seven cadaveric specimens. The fibula was translated 2.5mm and 5mm in the anterior and posterior directions. Four orthopedic trauma-trained surgeons were presented with a fictitious case consisting of a "normal" image, followed by 10 randomly selected images from both ankles, and were asked to determine if the fibula was reduced, or displaced anteriorly or posteriorly. The ability of the surgeons to identify displacement and inter-observer reliability were assessed. RESULTS:: The surgeons were better able to identify malreduction than reduction (NPV 95% ipsilateral, 85% contralateral). The overall sensitivity for reduction was 94% for the ipsilateral ankle, but only 68% for the contralateral ankle. Anterior displacement and greater magnitudes of displacement were most easily diagnosed. All reviewers had the most difficulty with 2.5mm of posterior displacement. The intraobserver agreement was excellent for anterior displacement and 5mm of displacement in either direction (kappa .71/.75). Surgeons who routinely used the contralateral lateral radiograph were more accurate. CONCLUSIONS:: While it is unknown how much translational displacement of the syndesmosis is acceptable, it seems that the experienced surgeon will be able to reduce the joint within 2.5mm and that fluoroscopic comparisons to the normal ankle are helpful in determining malreduction.
PMID: 25635357
ISSN: 0890-5339
CID: 1447982

A Biomechanical Study of Posteromedial Tibial Plateau Fracture Stability: Do They All Require Fixation?

Cuellar, Vanessa G; Martinez, Danny; Immerman, Igor; Oh, Cheongeun; Walker, Peter S; Egol, Kenneth A
OBJECTIVES: While the posteromedial fragment in tibial plateau fractures is often considered unstable, biomechanical evidence supporting this view is lacking. We aimed to evaluate the stability of the fragment in a cadaver model. Our hypothesis was that under the expected small axial force during rehabilitation and the combined effects of this force with shear force, internal rotation torque and varus moment, the most common posteromedial tibia fragment morphology could maintain stability in early flexion. METHODS: Axial compression force alone or combined with either posterior shear, internal rotation torque, or varus moment was applied to the femurs of five fresh cadaveric knees. A Tekscan pressure mapping system was used to measure pressure and contact area between the femoral condyles, meniscus, and tibial plateau. A Microscribe 3D digitizer was used to define the three-dimensional positions of the femur and tibia. A 10 mm and then a 20 mm osteotomy was created with a saw at an angle of 30 degrees in the axial plane with respect to the tangent of the posterior tibial plateau and 75 degrees in the sagittal plane, representing a typical posteromedial fracture fragment. At each flexion angle (15 degrees , 30 degrees , 60 degrees , 90 degrees , 120 degrees ) and loading condition (axial compression only, compression with shear force, torque, and varus moment), distal displacement of the medial femoral condyle as well as the tibial fracture fragments, were determined. RESULTS: For the 10 mm fragment, medial femoral condyle displacement was little affected up to approximately 30 degrees flexion, after which it increased. For the 20 mm fragment, there was progressive medial femoral condyle displacement with increasing flexion from baseline. However, for the 10mm and 20mm fragments themselves, displacements were noted at every flexion angle, starting at 1.7mm inferior displacement with 15 degrees of flexion and internal rotation torque and up to 10.2mm displacement with 90 degrees flexion and varus bending moment. CONCLUSIONS: In this cadaveric model of a posteromedial tibial plateau fracture, both fracture fragments studied displaced with knee flexion, even at low flexion angles. While such fragments may initially appear non-displaced after injury, posteromedial fragments similar to these tested are likely to displace during knee range of motion exercises in non-weight bearing conditions.
PMID: 25591035
ISSN: 0890-5339
CID: 1436422

Measurement reproducibility of magnetic resonance imaging-based finite element analysis of proximal femur microarchitecture for in vivo assessment of bone strength

Chang, Gregory; Hotca-Cho, Alexandra; Rusinek, Henry; Honig, Stephen; Mikheev, Artem; Egol, Kenneth; Regatte, Ravinder R; Rajapakse, Chamith S
INTRODUCTION: Osteoporosis is a disease of weak bone. Our goal was to determine the measurement reproducibility of magnetic resonance assessment of proximal femur strength. METHODS: This study had institutional review board approval, and written informed consent was obtained from all subjects. We obtained images of proximal femur microarchitecture by scanning 12 subjects three times within 1 week at 3T using a high-resolution 3-D FLASH sequence. We applied finite element analysis to compute proximal femur stiffness and femoral neck elastic modulus. RESULTS: Within-day and between-day root-mean-square coefficients of variation and intraclass correlation coefficients ranged from 3.5 to 6.6 % and 0.96 to 0.98, respectively. CONCLUSION: The measurement reproducibility of magnetic resonance assessment of proximal femur strength is suitable for clinical studies of disease progression or treatment response related to osteoporosis bone-strengthening interventions.
PMCID:4605426
PMID: 25487834
ISSN: 0968-5243
CID: 1393492

Displaced Intra-Articular Fractures Involving the Volar Rim of the Distal Radius

Marcano, Alejandro; Taormina, David P; Karia, Raj; Paksima, Nader; Posner, Martin; Egol, Kenneth A
PURPOSE: To describe the features of displaced intra-articular fractures confined to the volar rim of the distal radius and compare outcomes after their operative fixation to complete intra-articular and extra-articular fractures treated with operative fixation. METHODS: A total of 627 distal radius fractures were treated over a 6-year period. Twenty-eight patients had volar rim fractures (type 23-B3, as classified by the Orthopaedic Trauma Association [OTA]), all treated with operative reduction and fixation using a volar buttress plate. Clinical outcome information including radiographs, Short Form-36 health survey, and Disabilities of the Arm, Shoulder, and Hand questionnaire were collected at regular postoperative intervals. Patients with volar rim fractures were compared with patients who sustained other types of operatively managed distal radius fractures (OTA types 23-A, 23-B1/B2, and 23-C). RESULTS: The most common type of volar rim fracture consisted of a single large fragment (OTA 23-B3.2; 46%), followed by comminuted fractures (OTA 23-B3.3; 36%). Restoration of radiographic parameters was similar between groups except for an increased volar tilt in volar rim fractures compared with group 23-B1/B2. Active wrist and finger motion improved in all groups except for wrist extension, which was less in the 23-B1/B2 groups. The 23-B1/B2 group had the greatest pain and worst Short Form-36 scores. Disabilities of the Arm, Shoulder, and Hand questionnaire scores were similar and without differences between groups. CONCLUSIONS: Our data suggest that patients with volar rim distal radius fractures can expect a rapid return to function with minimal risk for complications and have outcomes similar to other types of operatively treated distal radius fractures. Further investigation of type 23-B fractures (23-B1/B2) is warranted owing to evidence of diminished outcomes. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III.
PMID: 25446998
ISSN: 0363-5023
CID: 1370352

Development of Compartment Syndrome Negatively Impacts Length of Stay and Cost Following Tibia Fracture

Crespo, Alexander M; Manoli, Arthur 3rd; Konda, Sanjit R; Egol, Kenneth A
OBJECTIVES:: To quantify the impact of compartment syndrome in the setting of tibial shaft fracture on hospital length of stay and total hospital charges. DESIGN:: Retrospective case-control study. SETTING:: All New York State hospital admissions from 2001-2011, as recorded by the New York Statewide Planning and Research Cooperative System (SPARCS) database. PATIENTS:: 33,629 inpatients with isolated open or closed fractures of the tibia and/or fibula (AO/OTA 41-43). 692 patients developed a compartment syndrome in the setting of tibia fracture. All patients were filtered to ensure none had other complications or medical comorbidities that would increase length of stay or total hospital charges. INTERVENTION:: Fasciotomy and delayed closure in patients who developed a compartment syndrome. MAIN OUTCOME MEASURE:: Hospital length of stay (days) and total inflation-adjusted hospital charges RESULTS:: A total of 33,629 patients with tibial shaft fracture were included in the study. There were 32,937 patients who did not develop a compartment syndrome. For this group, the mean length of stay was 6 days and the mean inflation-adjusted hospital charges were $34,000. Patients who developed compartment syndrome remained in-house for an average of 14 days with average charges totaling $79,000. These differences were highly significant for both lengths of stay and hospital charges (p < 0.001). CONCLUSION:: Besides the obvious physical detriment experienced by patients with compartment syndrome, there is also a significant economic impact to the healthcare system. Compartment syndrome following a tibial fracture more than doubles length of stay and total hospital charges. These findings highlight the need for a standardized care algorithm aimed towards efficiently and adequately treating acute compartment syndrome. Such an algorithm would optimize cost of care and presumably decrease length of stay. LEVEL OF EVIDENCE:: Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.
PMID: 25463427
ISSN: 0890-5339
CID: 1370892