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83


Three-dimensional MRI Bone Models of the Glenohumeral Joint Using Deep Learning: Evaluation of Normal Anatomy and Glenoid Bone Loss

Cantarelli Rodrigues, Tatiane; Deniz, Cem M; Alaia, Erin F; Gorelik, Natalia; Babb, James S; Dublin, Jared; Gyftopoulos, Soterios
Purpose/UNASSIGNED:To use convolutional neural networks (CNNs) for fully automated MRI segmentation of the glenohumeral joint and evaluate the accuracy of three-dimensional (3D) MRI models created with this method. Materials and Methods/UNASSIGNED:Shoulder MR images of 100 patients (average age, 44 years; range, 14-80 years; 60 men) were retrospectively collected from September 2013 to August 2018. CNNs were used to develop a fully automated segmentation model for proton density-weighted images. Shoulder MR images from an additional 50 patients (mean age, 33 years; range, 16-65 years; 35 men) were retrospectively collected from May 2014 to April 2019 to create 3D MRI glenohumeral models by transfer learning using Dixon-based sequences. Two musculoskeletal radiologists performed measurements on fully and semiautomated segmented 3D MRI models to assess glenohumeral anatomy, glenoid bone loss (GBL), and their impact on treatment selection. Performance of the CNNs was evaluated using Dice similarity coefficient (DSC), sensitivity, precision, and surface-based distance measurements. Measurements were compared using matched-pairs Wilcoxon signed rank test. Results/UNASSIGNED:value range, .097-.99). Conclusion/UNASSIGNED:© RSNA, 2020.
PMCID:7529433
PMID: 33033803
ISSN: 2638-6100
CID: 4627252

Radiographic features and complications following coracoclavicular ligament reconstruction

Kennedy, Brian P; Rosenberg, Zehava Sadka; Alaia, Michael J; Samim, Mohammad; Alaia, Erin F
OBJECTIVE:To report radiographic features and complications of coracoclavicular ligament reconstruction and the association of radiographic features with symptomatology. MATERIALS AND METHODS/METHODS:Retrospective picture archiving and communication system query (1/2012-8/2018) identified subjects with prior coracoclavicular ligament reconstruction. Post-operative radiographs were reviewed with attention to the following: (1) acromioclavicular alignment, (2) coracoclavicular width, (3) distal clavicular osteolysis, (4) osseous tunnel widening, and (5) hardware complication or fracture. Medical records were reviewed to determine purpose of imaging follow-up (symptomatic versus routine). Statistical analysis determined associations between binary features and outcomes, and inter-reader agreement. RESULT/RESULTS:Review of 55 charts identified 32 subjects (23 male, 9 females; age range 24-64; imaged 1-34 months following surgery) meeting inclusion criteria. Loss of acromioclavicular reduction was the most common imaging finding (n = 25, 78%), with 76% progressing to coracoclavicular interval widening. Distal clavicular osteolysis was seen in 21 cases (66%) and was significantly associated with loss of acromioclavicular joint reduction (p = 0.032). Tunnel widening occurred in 23 patients (82%) with more than one follow-up radiograph. Six (19%) had hardware complication or fracture. No radiographic feature or complication had significant correlation with symptomatology (p values 0.071-0.721). Inter-reader agreement was moderate to substantial for coracoclavicular interval widening and hardware complication, fair to substantial for tunnel widening, and fair to moderate for loss of acromioclavicular reduction and distal clavicular osteolysis. CONCLUSION/CONCLUSIONS:Loss of acromioclavicular joint reduction, coracoclavicular interval widening, distal clavicular osteolysis, and tunnel widening are common radiographic features after coracoclavicular ligament reconstruction; however, they do not necessarily correlate with symptomatology.
PMID: 31925463
ISSN: 1432-2161
CID: 4257832

Shoulder MR Imaging and MR Arthrography Techniques: New Advances

Alaia, Erin F; Subhas, Naveen
MR imaging is the standard diagnostic modality that provides a comprehensive and accurate assessment for both osseous and soft-tissue pathologic conditions of the shoulder. This article discusses standard MR imaging and arthrography protocols used routinely in clinical practice, as well as more innovative sequences and reconstruction techniques, facilitated by the increasing availability of high-field-strength magnets and multichannel phased array surface coils and incorporation of artificial intelligence. These exciting innovations allow for a more detailed and diagnostic imaging assessment, improvements in image quality, and more rapid image acquisition.
PMID: 32241655
ISSN: 1557-9786
CID: 4371562

CROHN'S DISEASE PHENOTYPE AND ACTIVITY ARE NOT ASSOCIATED WITH SACROILIITIS IN PATIENTS UNDERGOING MAGNETIC RESONANCE ENTEROGRAPHY [Meeting Abstract]

Levine, Irving; Malik, Fardina; Castillo, Gabriel; Jaros, Brian; Alaia, Erin; Ream, Justin; Scher, Jose; Hudesman, David; Axelrad, Jordan E.
ISI:000540349503073
ISSN: 0016-5085
CID: 5524192

Anteroposterior Radiograph of the Ankle with Cross-Sectional Imaging Correlation

Lin, Dana J; Alaia, Erin F; Rossi, Ignacio Martín; Zember, Jonathan; Rosenberg, Zehava Sadka
The focus of this article is to illustrate various pathologic entities and variants, heralding disease about the ankle, based on scrutiny of AP radiographs of the ankle, with correlative findings on cross-sectional imaging. Many of these entities can only be detected on the AP ankle radiograph and, if not recognized, may lead to delayed diagnosis and persistent morbidity to the patient. However, a vigilant radiologist, equipped with the knowledge of the characteristic appearance and typical locations of the imaging findings, should be able to make the crucial initial diagnosis and surmise additional findings to be confirmed on cross-sectional imaging.
PMID: 31575401
ISSN: 1557-9786
CID: 4115642

Magnetic resonance enterography as a screening tool to detect sacroiliitis in crohn's disease: Association with clinical and endoscopic Markers of Crohn's Disease Activity [Meeting Abstract]

Malik, F; Levine, I; Castillo, G; Jaros, B; Alaia, E; Ream, J; Axelrad, J E; Hudesman, D P; Scher, J
Background/Purpose : Prevalence of sacroiliitis (SI) in Crohn's disease (CD) varies widely (range 4% -39%), depending on criteria utilized to define the disease (e.g. inflammatory back pain, plain radiographs or MRI). Sacroiliitis may remain underdiagnosed in CD patients given lack of association with clinical symptoms of back pain and CD activity. However, patients with CD often undergo magnetic resonance enterography (MRE) to assess extent, severity of small bowel CD and radiographic healing, affording clinicians the opportunity to evaluate for the presence of active and/or chronic SI. We sought to identify the prevalence of sacroiliitis in CD patients utilizing MRE and determine its relationship with CD activity, especially with concurrent biologic therapy. Methods : All CD subjects undergoing MRE between years 2014-2018 at a large IBD referral center were identified. A musculoskeletal radiologist, blinded to clinical data, reviewed all MRE exams for the presence of acute bone marrow edema (BME) lesions and chronic lesions suggestive of acute and chronic SI, respectively. A second radiologist, also blinded, assessed MRE for mucosal CD activity using validated measures. Charts were reviewed for demographics, IBD characteristics, presence of back pain, clinical and endoscopic activity of CD, and Crohn's therapies within 3 months of MRE. Comparisons were made between CD subjects with and without SI using chi-square test. Univariate and multivariate logistic regression were used to determine risk factors of SI. Results : 258 subjects with CD underwent MRE during the study period with a mean age of 35 years old, 53% (n=138) were male, and mean duration of CD at the time of MRE was 9 years. Few reported back pain (8%) and 14% had previously seen a rheumatologist. Overall, 17% (n=45) of patients had MR evidence of sacroiliitis (Table 1). Female gender, presence of back pain, and later age of CD diagnosis were associated with signs of sacroiliitis (p=0.05, p< 0.001, p=0.04 respectively; Table 2). Stricturing phenotype was associated with a lower rate of SI (7% vs. 24%; p=0.018), but inflammatory or penetrating phenotypes were not. CD location, activity as noted by clinical scores, endoscopic disease activity, or radiographic disease activity on MRE, were not associated with sacroiliitis (Table 2). On multivariable analysis, back pain was associated with the presence of sacroiliitis on MRE (OR 3.0, 95% CI 1.1-5.6; p=0.04). Concurrent CD therapy with biologics did not lower the risk of sacroiliitis. Conclusion : Although often underdiagnosed, SI is a common comorbid condition in CD. While recent history of back pain was associated with the presence of sacroiliitis visualized on MRE, no correlations were found with other clinical and endoscopic markers of CD activity. Moreover, concurrent CD therapy, especially biologics, was not associated with a lower risk of sacroiliitis on MRE. With limited clinical clues and CD characteristics to suggest sacroiliitis, gastroenterologists can utilize MRE as a screening tool to detect SI and refer CD patients to rheumatologists. Presence of SI on MRE in CD patients with back pain may help identify a subset of individuals likely to benefit from switching to therapies with proven efficacy in axial SpA
EMBASE:633059004
ISSN: 2326-5205
CID: 4633642

Stener-Like Lesions of the Superficial Medial Collateral Ligament of the Knee: MRI Features

Alaia, Erin F; Rosenberg, Zehava Sadka; Alaia, Michael J
OBJECTIVE. The purpose of this article is to describe Stener-like lesions of the superficial medial collateral ligament (sMCL) of the knee, which, to our knowledge, have not yet been reported in the radiologic literature. This lesion, defined as a distal tear with interposition of osseous or soft-tissue structures between the ligament and its tibial attachment, often requires surgical intervention. MATERIALS AND METHODS. Knee MRI examinations of grade 3 sMCL tears were identified via a search of department imaging and orthopedic case files of medial collateral ligament (MCL) tears for the period of January 2010-April 2017 using the keywords "complete MCL tear" or "near complete MCL tear." Two musculoskeletal radiologists reviewed the MRI examinations. The location of the sMCL tear, presence of a Stener-like lesion, associated ligamentous injuries, and surgical findings were recorded. RESULTS. Review of 65 knee MRI examinations identified 20 cases of distal tibial grade 3 sMCL tear. Of the distal tears, 12 (60%) were Stener-like lesions and six (30%) were borderline lesions. Of these 18 cases, 14 (78%) were associated with multiligament knee injury and nine (50%) underwent MCL repair or reconstruction. Ten of the 12 (83%) Stener-like lesions were displaced superficial to the pes anserinus and two (17%) were entrapped, one in a reverse Segond fracture and one in the femorotibial compartment. CONCLUSION. Stener-like lesions represent a high percentage of tibia-sided sMCL avulsions, are found most often with pes anserinus interposition, and are frequently associated with multiligamentous injury, suggesting high-energy trauma. MRI diagnosis is important because interposition preventing anatomic healing and potential secondary valgus instability often prompt surgical intervention.
PMID: 31461317
ISSN: 1546-3141
CID: 4054482

Loss of reduction is common after coracoclavicular ligament reconstruction [Meeting Abstract]

Kennedy, B; Alaia, E; Alaia, M
Purpose: Soft tissue reconstruction of the coracoclavicular ligament is an increasingly common treatment approach for significant acromioclavicular joint separation injury. We have anecdotally noted loss of acromioclavicular joint reduction, coracoclavicular interval widening, distal clavicular osteolysis, and widening of osseous tunnels on follow-up radiographic exams. Our purpose is to report radiographic features and complications following coracoclavicular soft tissue reconstruction.
Material(s) and Method(s): Retrospective query of our imaging database identified 55 cases of coracoclavicular ligament reconstruction. Cases with at least one month of follow-up and available operative report were reviewed with attention to : 1. alignment of the acromioclavicualar joint, 2. coracoclavicular interval widening, 3. radiographic features of distal clavicular osteolysis, and 4. widening of the reconstruction tunnel.
Result(s): 32 patients with post-operative imaging following coracoclavicular ligament reconstruction (23 male, 9 females; average age 43, age range 24-64, imaged 1 to 34 months following surgery, average 9.5 months) were included. Loss of acromioclavicular joint reduction was the most common imaging finding at follow-up (n = 25, 78%), with 88% of cases seen within 6 months of surgery. 19 (76%) patients with loss of acromioclavicular reduction progressed to coracoclavicular interval widening. Distal clavicular osteolysis was seen in 21 patients (66%), with 90% of cases seen within 6 months of surgery. Reconstruction tunnels widened on average 2 mm (range 0 - 4 mm). Revision surgery was required in 5 patients (16%), with 80% of revisions occurring more than a year following surgery.
Conclusion(s): Loss of acromioclavicular joint reduction, distal clavicular osteolysis, and tunnel widening are frequently demonstrated after coracoclavicular ligament reconstruction. Radiologists should be aware of the frequently observed imaging findings following coracoclavicular reconstruction. Attention to early loss of reduction or distal clavicular may guide treatment approach and impact patient outcomes
EMBASE:626362748
ISSN: 0364-2348
CID: 3690372

Normal Anatomy and Traumatic Injury of the Midtarsal (Chopart) Joint Complex: An Imaging Primer

Walter, William R; Hirschmann, Anna; Alaia, Erin F; Tafur, Monica; Rosenberg, Zehava S
The midtarsal (Chopart) joint complex consists of the talonavicular and calcaneocuboid joints and their stabilizing ligaments. Detailed assessment of this complex at MRI can be challenging owing to frequent anatomic variation and the small size of the structures involved. Nevertheless, a wide spectrum of pathologic conditions affect the joint complex, and its imaging evaluation deserves more thorough consideration. This review focuses on MRI evaluation of normal ligamentous anatomy and common variations about the Chopart joint, presenting practical imaging tips and potential diagnostic pitfalls. Imaging findings across a spectrum of traumatic Chopart joint injuries are also reviewed, from midtarsal sprains to Chopart fracture-dislocations. Midtarsal sprains-commonly associated with ankle inversion injuries-are emphasized, along with their often predictable radiographic and MRI injury patterns. Online DICOM image stacks are available for this article. ©RSNA, 2018.
PMID: 30500305
ISSN: 1527-1323
CID: 3573482

The Prevalence and Clinical Associations of Sacroiliitis in Crohn's Disease Using a Standardized Magnetic Resonance Scoring System [Meeting Abstract]

Levine, Irving; Malik, Fardina; Castillo, Gabriel; Jaros, Brian D.; Alaia, Erin; Ream, Justin; Scher, Jose U.; Hudesman, David P.; Axelrad, Jordan E.
ISI:000509756002037
ISSN: 0002-9270
CID: 5524172