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89


Orthostatic Challenge Reveals Subtle Sympathetic Cardiac Dysfunction in Patients with Mild Traumatic Brain Injury [Meeting Abstract]

Hilz, MJ; Anders, S; Aurnhammer, F; Marthol, H; Baltadhzieva, R; Schroeder, T; Rossmeissl, A; Flanagan, S
ISI:000264527902501
ISSN: 0028-3878
CID: 104737

Ocular Pressure Test Shows Subtle Autonomic Cardiovascular Dysfunction in Patients with Mild Traumatic Brain Injury [Meeting Abstract]

Hilz, MJ; Aurnhammer, F; Anders, S; Marthol, H; Blaszczynska, P; Schroeder, T; Rossmeissl, A; Flanagan, S
ISI:000264527902356
ISSN: 0028-3878
CID: 104736

Managing agitation associated with traumatic brain injury: behavioral versus pharmacologic interventions? [Case Report]

Flanagan, Steven R; Elovic, Elie P; Sandel, Elizabeth
PMID: 19627876
ISSN: 1934-1482
CID: 104362

Pharmacological treatment for cognitive disorders of neurovascular origin

Chapter by: Flanagan, Steven; Gordon, Wayne A
in: Neurovascular neuropsychology by Festa, Joanne R [Eds]
New York, NY, US: Springer Science + Business Media, 2009
pp. 1846-1854
ISBN: 978-0-387-70713-6
CID: 5179

Traumatic brain injury: future assessment tools and treatment prospects

Flanagan, Steven R; Cantor, Joshua B; Ashman, Teresa A
Traumatic brain injury (TBI) is widespread and leads to death and disability in millions of individuals around the world each year. Overall incidence and prevalence of TBI are likely to increase in absolute terms in the future. Tackling the problem of treating TBI successfully will require improvements in the understanding of normal cerebral anatomy, physiology, and function throughout the lifespan, as well as the pathological and recuperative responses that result from trauma. New treatment approaches and combinations will need to be targeted to the heterogeneous needs of TBI populations. This article explores and evaluates the research evidence in areas that will likely lead to a reduction in TBI-related morbidity and improved outcomes. These include emerging assessment instruments and techniques in areas of structural/chemical and functional neuroimaging and neuropsychology, advances in the realms of cell-based therapies and genetics, promising cognitive rehabilitation techniques including cognitive remediation and the use of electronic technologies including assistive devices and virtual reality, and the emerging field of complementary and alternative medicine
PMCID:2626927
PMID: 19183780
ISSN: 1176-6328
CID: 96067

MRI findings in the painful poststroke shoulder

Shah, Rajiv R; Haghpanah, Sepideh; Elovic, Elie P; Flanagan, Steven R; Behnegar, Anousheh; Nguyen, Vu; Page, Stephen J; Fang, Zi-Ping; Chae, John
BACKGROUND AND PURPOSE: We describe the structural abnormalities in the painful shoulder of stroke survivors and their relationships to clinical characteristics. Method- Eighty-nine chronic stroke survivors with poststroke shoulder pain underwent T1- and T2-weighted multiplanar, multisequence MRI of the painful paretic shoulder. All scans were reviewed by one radiologist for the following abnormalities: rotator cuff, biceps and deltoid tears, tendinopathies and atrophy, subacromial bursa fluid, labral ligamentous complex abnormalities, and acromioclavicular capsular hypertrophy. Clinical variables included subject demographics, stroke characteristics, and the Brief Pain Inventory Questions 12. The relationship between MRI findings and clinical characteristics was assessed through logistic regression. RESULTS: Thirty-five percent of subjects exhibited a tear of at least one rotator cuff, biceps or deltoid muscle. Fifty-three percent of subjects exhibited tendinopathy of at least one rotator cuff, bicep or deltoid muscle. The prevalence of rotator cuff tears increased with age. However, rotator cuff tears and rotator cuff and deltoid tendinopathies were not related to severity of poststroke shoulder pain. In approximately 20% of cases, rotator cuff and deltoid muscles exhibited evidence of atrophy. Atrophy was associated with reduced motor strength and reduced severity of shoulder pain. CONCLUSIONS: Rotator cuff tears and rotator cuff and deltoid tendinopathies are highly prevalent in poststroke shoulder pain. However, their relationship to shoulder pain is uncertain. Atrophy is less common but is associated with less severe shoulder pain
PMCID:2398766
PMID: 18388345
ISSN: 1524-4628
CID: 83264

Congenital and acquired brain injury. 2. Medical rehabilitation in acute and subacute settings

Flanagan, Steven R; Kwasnica, Christina; Brown, Allen W; Elovic, Elie P; Kothari, Sunil
This self-directed learning module reviews common clinical problems and issues pertaining to early management of persons with traumatic brain injury (TBI). It is part of the study guide on brain injury medicine in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. Acute TBI is frequently complicated by agitation, dystonia, and numerous orthopedic and neurologic comorbidities, often causing a decrement in function, which requires careful assessment and treatment. Individuals with acute brain injury typically receive rehabilitation in a setting determined by numerous factors, including medical stability and tolerance to rehabilitation interventions. OVERALL ARTICLE OBJECTIVES: To describe (a) common traumatic brain injury-related comorbidities and treatment strategies, (b) potential causes of declining patient performance, and (c) appropriate settings for rehabilitation interventions
PMID: 18295656
ISSN: 1532-821x
CID: 83263

Congenital and acquired brain injury. 3. Spectrum of the acquired brain injury population

Kwasnica, Christina; Brown, Allen W; Elovic, Elie P; Kothari, Sunil; Flanagan, Steven R
This self-directed learning module highlights the subpopulations of traumatic brain injury (TBI) that are treated by the rehabilitation practitioner. It is part of the chapter on TBI in the self-directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. Specifically, this article focuses on the management of patients with mild TBI, children, and individuals with acquired brain injury from other etiologies, such as anoxic events or neoplastic lesions. The clinical spectrum of TBI, from the most severe presentation to the mildest, requires similar clinical skills to evaluate and manage. OVERALL ARTICLE OBJECTIVE: To describe the spectrum of brain injury populations based on age, severity, and etiology
PMID: 18295644
ISSN: 1532-821x
CID: 83259

Congenital and acquired brain injury. 4. Outpatient and community reintegration

Elovic, Elie P; Kothari, Sunil; Flanagan, Steven R; Kwasnica, Christina; Brown, Allen W
This self-directed learning module highlights the rehabilitation aspects of care for people with traumatic brain injury (TBI) after the acute phase. It focuses on issues important to community reentry, outpatient care, and return to work. It is part of the chapter on TBI medicine in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. This article specifically focuses on the formulation of rehabilitation plans to address the issues of cognitive dysfunction, behavioral disturbances, and community reintegration. Topics covered include pharmacologic and nonpharmacologic approaches to cognitive and affective disorders, intimacy, social isolation, mobility, and return to work. Finally, the critical issues of legal competency and obtaining informed consent in the population with cognitive impairment are discussed. OVERALL ARTICLE OBJECTIVE: To summarize the issues that affect outpatient care, independence, and community reentry after traumatic brain injury
PMID: 18295645
ISSN: 1532-821x
CID: 83260

Congenital and acquired brain injury. 5. Emerging concepts in prognostication, evaluation, and treatment

Kothari, Sunil; Flanagan, Steven R; Kwasnica, Christina; Brown, Allen W; Elovic, Elie P
This self-directed learning module describes recent developments in the field of traumatic brain injury (TBI) rehabilitation. In particular, it focuses on the implications of recent technological advances for evaluation, prognostication, and treatment. It is part of the chapter on TBI medicine in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. This article specifically focuses on neuroplasticity and its implications for rehabilitation interventions, the role of innovative neuroimaging modalities, improvements in our ability to prognosticate made possible by newer technologies, technologically based enhancement of motor rehabilitation, and the role of alternative and complementary medicine in TBI rehabilitation. OVERALL ARTICLE OBJECTIVE: To describe recent advances in our ability to evaluate, prognosticate, and treat traumatic brain injury
PMID: 18295646
ISSN: 1532-821x
CID: 83261