Searched for: in-biosketch:true
person:hacquj01
Evaluation of instrumentation and pedicle screw design for posterior lumbar fixation: A pre-clinical in vivo/ex vivo ovine model
Witek, Lukasz; Parente, Paulo Eduardo Lima; Torroni, Andrea; Greenberg, Michael; Nayak, Vasudev Vivekanand; Hacquebord, Jacques Henri; Coelho, Paulo G
BACKGROUND/UNASSIGNED:" osseodensification rotary drilling compacts the bone fragments into the osteotomy walls, creating nucleating sites for regeneration. METHODS/UNASSIGNED:This study aimed to compare both manual versus rotary Osseodensification (OD) instrumentation as well as two different pedicle screw thread designs in a controlled split animal model in posterior lumbar stabilization to determine the feasibility and potential advantages of each variable with respect to mechanical stability and histomorphology. A total of 164 single thread (82 per thread configuration), pedicle screws (4.5 × 35 mm) were used for the study. Each animal received eight pedicles (four per thread design) screws, which were placed in the lumbar spine of 21 adult sheep. One side of the lumbar spine underwent rotary osseodensification instrumentation, while the contralateral underwent conventional, hand, instrumentation. The animals were euthanized after 6- and 24-weeks of healing, and the vertebrae were removed for biomechanical and histomorphometric analyses. Pullout strength and histologic analysis were performed on all harvested samples. RESULTS/UNASSIGNED: = 0.026) greater pullout strength (1060.6 N ± 181) relative to hand instrumentation (769.3 N ± 181) at the 24-week healing time point. Histomorphometric analysis exhibited significantly higher degrees of bone to implant contact for the rotary instrumentation only at the early healing time point (6 weeks), whereas bone area fraction occupancy was statistically higher for rotary instrumentation at both healing times. The levels of soft tissue infiltration were lower for pedicle screws placed in osteotomies prepared using OD instrumentation relative to hand instrumentation, independent of healing time. CONCLUSION/UNASSIGNED:The rotary instrumentation yielded enhanced mechanical and histologic results relative to the conventional hand instrumentation in this lumbar spine stabilization model.
PMCID:10285755
PMID: 37361331
ISSN: 2572-1143
CID: 5540112
Determining the Optimal Dosage of Corticosteroid Injection in Trigger Finger
Bookman, Jared; Rocks, Madeline; Noh, Karen; Ayalon, Omri; Hacquebord, Jacques; Catalano, Louis; Glickel, Steven
BACKGROUND/UNASSIGNED:Corticosteroid injection is the mainstay of nonoperative treatment for trigger finger (stenosing tenosynovitis), but despite substantial experience with this treatment, there is minimal available evidence as to the optimal corticosteroid dosing. The purpose of this study is to compare the efficacy of 3 different injection dosages of triamcinolone acetonide for the treatment of trigger finger. METHODS/UNASSIGNED:Patients diagnosed with a trigger finger were prospectively enrolled and treated with an initial triamcinolone acetonide (Kenalog) injection of 5 mg, 10 mg, or 20 mg. Patients were followed longitudinally over a 6-month period. Patients were assessed for duration of clinical response, clinical failure, Visual Analog Scale (VAS) pain scores, and Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) scores. RESULTS/UNASSIGNED:A total of 146 patients (163 trigger fingers) were enrolled over a 26-month period. At 6-month follow-up, injections were still effective (without recurrence, secondary injection, or surgery) in 52% of the 5-mg group, 62% of the 10-mg group, and 79% of the 20-mg group. Visual Analog Scale at final follow-up improved by 2.2 in the 5-mg group, 2.7 in the 10-mg group, and 4.5 in the 20-mg group. The QuickDASH scores at final follow-up improved by 11.8 in the 5-mg group, 21.5 in the 10-mg group, and 28.9 in the 20-mg group. CONCLUSIONS/UNASSIGNED:Minimal evidence exists to guide the optimal dosing of steroid injection in trigger digits. When compared with 5-mg and 10-mg doses, a 20-mg dose was found to have a significantly higher rate of clinical effectiveness at 6-month follow-up. The VAS and QuickDASH scores were not significantly different between the 3 groups.
PMID: 37191248
ISSN: 1558-9455
CID: 5544232
Reducing Complications in Pilon Fracture Surgery: Surgical Time Matters
Shafiq, Babar; Zhang, Bo; Zhu, Diana; Gupta, Deven K; Cubberly, Mark; Stepanyan, Hayk; Rezzadeh, Kevin; Lim, Philip K; Hacquebord, Jacques; Gupta, Ranjan
OBJECTIVE:To correlate patient and surgeon specific factors with outcomes after operative management of distal intra-articular tibia fractures. DESIGN/METHODS:Retrospective cohort study. SETTING/METHODS:Three Level 1 tertiary academic trauma centers. PATIENTS/PARTICIPANTS/METHODS:A consecutive series of 175 patients with OTA/AO 43-C pilon fractures. MAIN OUTCOME MEASUREMENTS/METHODS:Primary outcomes include superficial and deep infection. Secondary outcomes include nonunion, loss of articular reduction, and implant removal. RESULTS:The following patient specific factors correlated with poor surgical outcomes: increased age with superficial infection rate (p<0.05), smoking with rate of nonunion (p<0.05), and Charlson Comorbidity Index with loss of articular reduction(p<0.05). Each additional 10 minutes of operative time over 120 minutes was associated with increased odds of requiring I&D and any treatment for infection. The same linear effect was seen with addition of each fibular plate. The number of approaches, type of approach, use of bone graft, and staging were not associated with infection outcomes. Each additional 10 minutes of operative time over 120 minutes was associated with increased rate of implant removal, as did fibular plating. CONCLUSIONS:While many of the patient-specific factors that negatively impact surgical outcomes for pilon fractures may not be modifiable, surgeon-specific factors need to be carefully examined as these may be addressed. Pilon fracture fixation has evolved to increasingly utilize fragment specific approaches applied with a staged approach. Although the number and type of approaches did not affect outcomes, longer operative time was associated with increased odds of infection while additional fibular plate fixation, was associated with higher odds of both infection and implant removal. Potential benefits of additional fixation should be weighed against operative time and associated risk of complications. LEVEL OF EVIDENCE/METHODS:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
PMID: 37226911
ISSN: 1531-2291
CID: 5508472
Anterior interosseous nerve palsy in the early postoperative period after open capsular release for elbow stiffness
Colasanti, Christopher A; Boin, Michael; Hacquebord, Jacques; Virk, Mandeep
Surgical release of elbow contracture is associated with injury to structures traversing the elbow. To date, only one other case report has been published describing anterior interosseous nerve (AIN) palsy that developed immediately after open elbow contracture release and debridement. Here we describe the unique case of a patient that developed AIN palsy 1 week after operation, including magnetic resonance imaging and electrodiagnostic studies, to shed some light on the etiology of this rare complication.
PMID: 37088884
ISSN: 2288-8721
CID: 5464902
Brachial Plexus Nerve Injuries and Disorders: MR Imaging-Ultrasound Correlation
Koneru, Sirisha; Nguyen, Vinh T; Hacquebord, Jacques H; Adler, Ronald S
Multimodality imaging of the brachial plexus is essential to accurately localize the lesion and characterize the pathology and site of injury. A combination of computed tomography (CT), ultrasound, and MR imaging is useful along with clinical and nerve conduction studies. Ultrasound and MR imaging in combination are effective to accurately localize the pathology in most of the cases. Accurate reporting of the pathology with dedicated MR imaging protocols in conjunction with Doppler ultrasound and dynamic imaging provides practical and useful information to help the referring physicians and surgeons to optimize medical or surgical treatment regimens.
PMID: 37019549
ISSN: 1557-9786
CID: 5463802
Evaluation of instrumentation and pedicle screw design for posterior lumbar fixation: A pre-clinical in vivo/ex vivo ovine model
Witek, Lukasz; Parente, Paulo Eduardo Lima; Torroni, Andrea; Greenberg, Michael; Nayak, Vasudev Vivekanand; Hacquebord, Jacques Henri; Coelho, Paulo G. G.
ISI:000915953900001
ISSN: 2572-1143
CID: 5439782
Distal Radius Fracture Management: Surgeon Factors Markedly Influence Decision Making
Doermann, Alex; Gupta, Deven K; Wright, David J; Shafiq, Babar; Hacquebord, Jacques; Rafijah, Gregory; Lim, Philip K; Gupta, Ranjan
INTRODUCTION/BACKGROUND:It is our hypothesis that physician-specific variables affect the management of distal radius (DR) fractures in addition to patient-specific factors. METHODS:A prospective cohort study was conducted evaluating treatment differences between Certificate of Additional Qualification hand surgeons (CAQh) and board-certified orthopaedic surgeons who treat patients at level 1 or level 2 trauma centers (non-CAQh). After institutional review board approval, 30 DR fractures were selected and classified (15 AO/OTA type A and B and 15 AO/OTA type C) to create a standardized patient data set. The patient-specific demographics and surgeon's information regarding the volume of DR fractures treated per year, practice setting, and years posttraining were obtained. Statistical analysis was done using chi-square analysis with a postanalysis regression model. RESULTS:A notable difference was observed between CAQh and non-CAQh surgeons. Surgeons in practice longer than 10 years or who treat >100 DR fractures/year were more likely to choose surgical intervention and obtain a preoperative CT scan. The two most influential factors in decision making were the patients' age and medical comorbidities, with physician-specific factors being the third most influential in medical decision making. DISCUSSION/CONCLUSIONS:Physician-specific variables have a notable effect on decision making and are critical for the development of consistent treatment algorithms for DR fractures.
PMCID:9984156
PMID: 36867522
ISSN: 2474-7661
CID: 5432412
The presence of 3D printing in orthopedics: A clinical and material review
Rodriguez Colon, Ricardo; Nayak, Vasudev Vivekanand; Parente, Paulo E L; Leucht, Philipp; Tovar, Nick; Lin, Charles C; Rezzadeh, Kevin; Hacquebord, Jacques H; Coelho, Paulo G; Witek, Lukasz
The field of additive manufacturing, 3D printing (3DP), has experienced an exponential growth over the past four decades, in part due to increased accessibility. Developments including computer-aided design and manufacturing, incorporation of more versatile materials, and improved printing techniques/equipment have stimulated growth of 3DP technologies within various industries, but most specifically the medical field. Alternatives to metals including ceramics and polymers have been garnering popularity due to their resorbable properties and physiologic similarity to extracellular matrix. 3DP has the capacity to utilize an assortment of materials and printing techniques for a multitude of indications, each with their own associated benefits. Within the field of medicine, advances in medical imaging have facilitated the integration of 3DP. In particular, the field of orthopedics has been one of the earliest medical specialties to implement 3DP. Current indications include education for patients, providers, and trainees, in addition to surgical planning. Moreover, further possibilities within orthopedic surgery continue to be explored, including the development of patient-specific implants. This review aims to highlight the use of current 3DP technology and materials by the orthopedic community, and includes comments on current trends and future direction(s) within the field.
PMID: 35634867
ISSN: 1554-527x
CID: 5235812
Degree of Soft Tissue Injury is a Major Determinant of Successful Arterial Repair in the Extremity: A New Classification of Extremity Arterial Injury?
Deng, Peijun; Yang, Jiantao; Hacquebord, Jacques Henri; Qin, Bengang; Wang, Honggang; Li, Ping; Gu, Liqiang; Qi, Jian; Zhu, Qingtang
BACKGROUND/UNASSIGNED:This study aimed to investigate outcomes after extremity arterial injury repair and examined the association between outcomes and the degree of soft tissue injury and vascular repair methods. METHODS/UNASSIGNED:A retrospective study was conducted on 106 patients (108 cases) who underwent emergent microsurgical repair of extremity arterial injury due to trauma and non-perfusion of the affected extremity. The cases were divided into three groups by degree of associated soft tissue injuries: (A) adequate soft tissue coverage over the injured major vessels after radical debridement, (B) inadequate soft tissue coverage over the injured major vessels after radical debridement, and (C) radical debridement was not feasible due to unclear extent of injured soft tissue. Differences in vascular repair methods and outcomes among the three groups were analyzed. RESULTS/UNASSIGNED: < 0.001). CONCLUSION/UNASSIGNED:The extent of associated soft tissue injury was associated with different vascular repair methods and outcomes. We propose a new system for classifying these injuries according to the degree of associated soft tissue injury.
PMID: 35361053
ISSN: 1521-0553
CID: 6074260
Complex upper extremity injuries: targeted muscle reinnervation, free functional muscle transfer, and vascularized composite allotransplantation
Bekisz, Jonathan; Hacquebord, Jacques H.
Restoration of upper extremity function poses a unique surgical challenge. With considerations ranging from ensuring appropriate skeletal support and musculotendinous and ligamentous anatomy, restoring adequate vascularity and innervation, and providing sufficient soft tissue coverage, upper extremity injuries present a diverse range of reconstructive problems. Recent history has been marked by an expansion of novel techniques for addressing these complex issues. Sophisticated modalities, such as targeted muscle reinnervation, free functional muscle transfer, and vascularized composite allotransplantation, have become some of the most powerful tools in the armamentarium of the reconstructive surgeon. This review article aims to define the distinguishing features of each of these modalities and reviews some of their unique advantages and limitations.
SCOPUS:85148477395
ISSN: 2347-9264
CID: 5426052