Searched for: in-biosketch:true
person:josepd10
Rhabdomyolysis and oliguric renal failure after use of TASER®: is it really safe? [Case Report]
Gross, Erica R; Porterieko, Joseph; Joseph, D'Andrea
PMID: 24351337
ISSN: 1555-9823
CID: 3488732
Successful nonoperative management of the most severe blunt renal injuries: a multicenter study of the research consortium of New England Centers for Trauma
van der Wilden, Gwendolyn M; Velmahos, George C; Joseph, D'Andrea K; Jacobs, Lenworth; Debusk, M George; Adams, Charles A; Gross, Ronald; Burkott, Barbara; Agarwal, Suresh; Maung, Adrian A; Johnson, Dirk C; Gates, Jonathan; Kelly, Edward; Michaud, Yvonne; Charash, William E; Winchell, Robert J; Desjardins, Steven E; Rosenblatt, Michael S; Gupta, Sanjay; Gaeta, Miguel; Chang, Yuchiao; de Moya, Marc A
IMPORTANCE/OBJECTIVE:Severe renal injuries after blunt trauma cause diagnostic and therapeutic challenges for the treating clinicians. The need for an operative vs a nonoperative approach is debated. OBJECTIVE:To determine the rate, causes, predictors, and consequences of failure of nonoperative management (NOM) in grade IV and grade V blunt renal injuries (BRIs). DESIGN/METHODS:Retrospective case series. SETTING/METHODS:Twelve level I and II trauma centers in New England. PARTICIPANTS/METHODS:A total of 206 adult patients with a grade IV or V BRI who were admitted between January 1, 2000, and December 31, 2011. MAIN OUTCOMES AND MEASURES/METHODS:Failure of NOM, defined as the need for a delayed operation or death due to renal-related complications during NOM. RESULTS:Of 206 patients, 52 (25.2%) were operated on immediately, and 154 (74.8%) were managed nonoperatively (with the assistance of angiographic embolization for 25 patients). Nonoperative management failed for 12 of the 154 patients (7.8%) and was related to kidney injury in 10 (6.5%). None of these 10 patients had complications because of the delay in BRI management. The mean (SD) time from admission to failure was 17.6 (27.4) hours (median time, 7.5 hours; range, 4.5-102 hours), and the cause was hemodynamic instability in 10 of the 12 patients (83.3%). Multivariate analysis identified 2 independent predictors of NOM failure: older than 55 years of age and a road traffic crash as the mechanism of injury. When both risk factors were present, NOM failure occurred for 27.3% of the patients; when both were absent, there were no NOM failures. Of the 142 patients successfully managed nonoperatively, 46 (32.4%) developed renal-related complications, including hematuria (24 patients), urinoma (15 patients), urinary tract infection (8 patients), renal failure (7 patients), and abscess (2 patients). These patients were managed successfully with no loss of renal units (ie, kidneys). The renal salvage rate was 76.2% for the entire population and 90.3% among patients selected for NOM. CONCLUSIONS AND RELEVANCE/CONCLUSIONS:Hemodynamically stable patients with a grade IV or V BRI were safely managed nonoperatively. Nonoperative management failed for only 6.5% of patients owing to renal-related injuries, and three-fourths of the entire population retained their kidneys.
PMID: 23945834
ISSN: 2168-6262
CID: 3488722
Diagnosing blunt hollow viscus injury: is computed tomography the answer?
Joseph, D'Andrea K; Kunac, Anastasia; Kinler, Rae Lynne; Staff, Ilene; Butler, Karyn L
BACKGROUND:Blunt hollow viscus injury (BHVI) is challenging to diagnose. The purpose of this study was to determine the reliability of physical exam and the role of computed tomography (CT) in the diagnosis of BHVI. METHODS:All blunt abdominal trauma (BAT) admissions to a level 1 trauma center from January 2009 through December 2011 were identified through the trauma registry. Data collected included demographics and findings on CT and physical exam. RESULTS:Of 2,912 patients with blunt trauma, 340 had BAT, and 30 (9%) had BHVIs. The sensitivity and specificity of CT were 86% and 88%, respectively, whereas the sensitivity and specificity of clinical exam were 53% and 69%. Twenty-seven percent of patients with BAT and bladder injuries had concomitant BHVIs. CONCLUSIONS:This is the largest single series of BHVI after BAT. CT is superior to clinical exam in establishing the diagnosis of BHVI. Although associated injuries are common, bladder injury may be an important marker for BHVI.
PMID: 23375703
ISSN: 1879-1883
CID: 3488712
Predictors of acute posttraumatic stress disorder symptoms following civilian trauma: Highest incidence and severity of symptoms after assault DISCUSSION [Editorial]
Davis, James W.; Croce, Martin; Dicker, Rochelle A.; Betts, James M.; Brasel, Karen J.; Joseph, D'Andrea; Alarcon, Louis H.
ISI:000301371100026
ISSN: 2163-0755
CID: 3488822
Percutaneous versus open tracheostomy in the pediatric trauma population
Raju, Ashish; Joseph, D'Andrea K; Diarra, Cheickna; Ross, Steven E
The purpose of this study was to determine the safety and efficacy of percutaneous versus open tracheostomy in the pediatric trauma population. A retrospective chart review was conducted of all tracheostomies performed on trauma patients younger than 18 years for an 8-year period. There was no difference in the incidence of brain, chest, or facial injury between the open and percutaneous tracheostomy groups. However, the open group had a significantly lower age (14.2 vs. 15.5 years; P < 0.01) and higher injury severity score (26 vs. 21; P = 0.015). Mean time from injury to tracheostomy was 9.1 days (range, 0 to 16 days) and was not different between the two methods. The majority of open tracheostomies were performed in the operating room and, of percutaneous tracheostomies, at the bedside. Concomitant feeding tube placement did not affect complication rates. There was not a significant difference between complication rates between the two methods of tracheostomy (percutaneous one of 29; open three of 20). Percutaneous tracheostomy can be safely performed in the injured older child.
PMID: 20349656
ISSN: 0003-1348
CID: 3488702
Decompressive laparotomy to treat intractable intracranial hypertension after traumatic brain injury
Joseph, D'Andrea K; Dutton, Richard P; Aarabi, Bizhan; Scalea, Thomas M
INTRODUCTION/BACKGROUND:Increases in intra-abdominal pressure (IAP) can cause increases in intracranial pressure (ICP). Recently, we noticed that abdominal fascial release could be useful in treating intracranial hypertension (ICH) after traumatic brain injury (TBI). We added this as an option in our treatment of TBI. METHODS:In our institution, ICH is treated with an algorithm using osmolar therapy, CSF drainage and barbiturates. Patients with refractory ICH have routine measurement of IAP. If elevated, consideration is given to decompressive laparotomy. We retrospectively reviewed all patients admitted from January 2000 through July 2003 who had abdominal decompression to treat refractory ICH. RESULTS:From 1/00 to 7/03, 17 patients underwent decompressive laparotomy for intractable ICH. Thirteen male and 4 females all sustained blunt injury. All had failed maximal therapy including 14 who had had decompressive craniectomy. Mean ICP was 30 +/- 8.1 mmHg (range 20-40 mmHg) before decompression. No patients had evidence of abdominal compartment syndrome (ACS). Before decompression mean IAP was 27.5 (+/- 5.2) mmHg (range 21-35 mmHg). After abdominal decompression ICP dropped precipitously by at least 10 mmHg to a mean of 17.5 (+/- 3.2) mmHg (range 10-25 mmHg). In 6 patients the decrease in ICP was transient. All died. The remaining 11 had sustained decreases in ICP. All survived, made neurologic recovery and were discharged to a rehabilitation facility. CONCLUSION/CONCLUSIONS:Decompressive laparotomy can be a useful adjunct in the treatment of ICH failing maximal therapy following TBI. More work will need to be done to precise the exact indications for this therapy.
PMID: 15514520
ISSN: 0022-5282
CID: 3488692