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Does butterfly fragment management affect healing following fixation of comminuted clavicle fractures?
Linker, Jacob A; Ganta, Abhishek; Konda, Sanjit R; Egol, Kenneth A
PURPOSE/OBJECTIVE:Evaluate healing outcomes of patients who sustained a comminuted clavicle fracture and underwent operative fixation using a bridge plate technique or interfragmentary screw/neutralization plate. METHODS:Two hundred and seventy-one comminuted clavicle fractures that underwent operative fixation with minimum 6 months follow-up were retrospectively reviewed. Patients were grouped based on fixation methods. Data collected include patient demographics and injury information. Fracture healing, total complications, fracture related infection, removal of hardware, nonunion, and revision fracture surgery were reviewed. Clinical healing was defined as non-tenderness about the fracture site, and radiographic healing was defined as bridging callus and/ or lack of fracture line on X-ray. Chi square analysis, T test, and linear regression were used for analysis. RESULTS:There were 126 comminuted fractures fixed with a bridge plate and 145 comminuted fractures fixed with a plate and at least one interfragmentary screw both with a mean follow-up of 8.2 months. The bridge plated group was more female, the result of high-energy mechanisms, and had more anteroinferior plates (p < 0.05 for all). There were no differences in time to radiographic healing as well as incidence of nonunion between cohorts. Patients fixed with the bridge plate technique underwent a higher incidence of revision surgery, higher incidence of hardware removal, and had a longer time until clinically healed. On multivariate regression analysis, fixation method was not associated with any of these outcomes (p < 0.05 for all). CONCLUSION/CONCLUSIONS:Bridge plating and lag screw/neutralization plate fixation were both associated with similar rates of healing. Complication profiles were similar.
PMID: 41091223
ISSN: 1432-1068
CID: 5954792
Posterior Sternoclavicular Joint Dislocation and Reconstruction [Case Report]
Lin, Charles C; Morgan, Allison; Doran, Michael; Jejurikar, Neha; Resad-Ferati, Sehar; Markus, Danielle H; Ganta, Abhishek; Konda, Sanjit R
This case presentation describes a technique for reconstruction of an acute posterior sternoclavicular joint dislocation. The patient was a 37 year-old female who sustained a left posterior sternoclavicular dislocation after a fall. A curvilinear incision was made directly over the sternoclavicular joint. After reduction, a semitendinosus allograft was used to reconstruct the sternoclavicular joint in a figure-of-8 fashion through drill holes in the manubrium and the proximal clavicle and secured with suture tape. Sternoclavicular reconstruction with semitendinosis allograft provides a reliable option with good clinical outcomes and low rates of recurrent instability.
PMID: 40932255
ISSN: 1531-2291
CID: 5936492
Technical Trick: Coronoid Fracture "Lasso" Repair Using Arthroscopic Instrumentation in Terrible Triad Injuries With Fixable Radial Head Fractures [Case Report]
Bi, Andrew S; Herbosa, Carolyn; Abola, Matthew V; Konda, Sanjit R; De Tolla, Jadie; Ganta, Abhishek
A single-stage operative repair of terrible triad injuries through a laterally-based approach using arthroscopic instrument-assisted reduction of the coronoid fracture in cases in which the radial head is deemed appropriate for repair rather than arthroplasty is described in this technical trick. Using an arthroscopic suture lasso, adjustable drill guides, cannulated guide-pins with nitinol shuttling wires, and a suspensory cortical button allow for a more precise and facile technique of "lasso" fixation of coronoid fractures and anterior capsular injuries with intact radial heads in terrible triad injuries.
PMID: 40932269
ISSN: 1531-2291
CID: 5936502
Monitored Anesthesia Care-Soft Tissue Infiltration with Local Anesthesia (MAC-STILA) Decreases Incidence of Short-Term Postoperative Altered Mental Status in Hip Fracture Patients
Fisher, Nina D; Kingery, Matthew T; Merrell, Lauren; Kadiyala, Manasa L; Reider, Lisa; Ganta, Abhishek; Egol, Kenneth A; Konda, Sanjit R
OBJECTIVE:To determine if the occurrence of short-term post-operative altered mental status (AMS) was lower in geriatric patients undergoing operative repair of hip fractures with Monitored Anesthesia Care and Soft-Tissue Infiltration with Local Anesthesia (MAC-STILA) when compared with general anesthesia (GA). DESIGN/METHODS:Retrospective cohort study. SETTING/METHODS:Two U.S. hospitals within a single academic medical center. PATIENT SELECTION CRITERIA/UNASSIGNED:Geriatric patients with hip fractures (AO/OTA 31A and 31B) undergoing operative repair were identified. Propensity matching was performed in a 1:2 ratio to minimize selection bias (age, sex, BMI, ASA class, fracture pattern, fixation construct, pre-injury ambulatory status, and assistive device use). OUTCOME MEASURES/METHODS:Patients who underwent surgical fixation with MAC-STILA were compared with GA. Primary outcome was post-operative AMS, defined as missing ≥1 items on the alert and oriented assessment (person, place, and time) at any point from post-operative days 0-3. RESULTS:After matching, 228 patients (76 MAC-STILA: 152 GA) were included in the analysis. The average age of patients in both groups was 83 years. In the MAC-STILA group, 62% were female and 33% had baseline dementia while in the GA group 66% were female and 29% had baseline dementia. Treating patients with MAC-STILA was associated with 72% lower odds of having AMS compared with GA, controlling for baseline comorbidity and dementia (OR: 0.28. 95% CI: 0.09-0.075, p=0.016). Among patients with baseline dementia, the rate of AMS was lower in patients treated with MAC-STILA compared with GA (64.0% vs 95.3%, p = 0.001). CONCLUSION/CONCLUSIONS:Monitored Anesthesia Care and Soft-Tissue Infiltration with Local Anesthesia (MAC-STILA) was associated with lower odds of short-term postoperative altered mental status (AMS) compared to general anesthesia (GA) in hip fracture patients undergoing operative repair. Given the high rate of post-operative AMS and complications associated with geriatric hip fracture patient, MAC-STILA should be considered for use in patients with increased risk of post-operative AMS, particularly in the setting of preoperative dementia. LEVEL OF EVIDENCE/METHODS:Therapeutic III.
PMID: 40952772
ISSN: 1531-2291
CID: 5934982
Isolated Fifth Metatarsal Fractures: A Spectrum of Patterns With Similar Clinical and Radiographic Outcomes Regardless of Management
Kadiyala, Manasa L; Kingery, Matthew T; Walls, Raymond; Leucht, Philipp; Ganta, Abhishek; Konda, Sanjit R; Egol, Kenneth A
INTRODUCTION/BACKGROUND:Several types of fifth metatarsal (MT) fractures exist and are treated with various methods of immobilization, weight bearing restrictions, and occasionally operative procedures. This study evaluated the differences in clinical and radiographic outcomes among pseudo-Jones fractures (Zones 1 and 2), true Jones fractures (Zone 3), and fifth metatarsal shaft and neck fractures. METHODS:A retrospective review of a consecutive series of patients presenting to a single academic medical center with a fifth metatarsal fracture between 2012 and 2022 was conducted. Radiographs obtained at the initial presentation were reviewed, and fracture patterns were categorized as either Zone 1, Zone 2, Zone 3, shaft, neck, or head fractures. RESULTS:In total, 1314 patients with isolated fifth metatarsal fractures were treated (mean age = 49.6 ± 18.0 years). In total, 1217 fractures (92.5%) were initially treated nonoperatively, and 97 fractures (7.5%) were treated operatively. The overall time to clinical and radiographic healing for all fifth metatarsal fractures treated nonoperatively was 9.9 ± 8.7 weeks and 17.9 ± 15.6 weeks, respectively (P = .245, P = .088). Immediate weightbearing led to a faster time to clinical healing by (P = .035). There was no statistically significant difference in time to clinical or radiographic union among the different fracture types (P = .496, P = .400). Likewise, there was no evidence of any difference in time to clinical or radiographic union for patients treated operatively versus nonoperatively (P > .05). CONCLUSION/CONCLUSIONS:.
PMID: 40968738
ISSN: 1938-7636
CID: 5935532
Predicting Contralateral Second Hip Fracture Risk Within 5 Years of First Hip Fracture: A New Risk Tool to Guide Patient/Family Counseling and Bone Health Treatment
Pettit, Christopher J; Herbosa, Carolyn F; Linker, Jacob A; Ganta, Abhishek; Egol, Kenneth A; Konda, Sanjit R
OBJECTIVE:To develop a stratification tool to identify hip fracture patients at risk for second contralateral hip fracture and mortality within 5 years of an index fracture, and to assess the cost-effectiveness of prophylactic fixation in high-risk/low-mortality patients. METHODS:Design: Retrospective prognostic cohort study. SETTING/METHODS:Single academic system with 2 Level 1 Trauma Centers, 1 orthopedic specialty hospital, and 1 tertiary care hospital. PATIENT SELECTION CRITERIA/UNASSIGNED:Patients who were 60 years or older with OTA 31A/B hip fractures from low-energy mechanisms between 11/1/2014 and 11/31/2023 with ≥5 years follow-up or until death were included. OUTCOME MEASURES AND COMPARISONS/UNASSIGNED:The study included four phases: (1) identifying factors associated with second hip fracture within 5 years; (2) using multivariate logistic regression to generate models predicting 5-year second hip fracture (vs. FRAX) and mortality risk; (3) creating a "risk matrix" to identify candidates for prophylactic fixation using Youden's Index which determined cutoff points encompassing the maximum sensitivity and specificity for each risk equation and were used to define a value-based target group; (4) cost analysis comparing standard vs. prophylactic care in high-risk/low-mortality patients. RESULTS:Of 426 patients (mean age 80.25 years, 73.4% female), 78 sustained second hip fractures (mean interval: 594 days). Predictors included higher FRAX score (p=0.004), dementia (p<.001), ICU stay (p=0.014), discharge to subacute care (p<.001), and 90-day readmission (p=0.011). Logistic regression predicted 5-year second fracture risk (AUC 0.742 vs. FRAX 0.617, p=0.012) and 5-year mortality (AUC 0.723). The risk matrix used cutoff points of 18.2% (mortality) and 38.2% (second fracture) to define a value-based target group (n=26; 13 experienced second fracture). Cost analysis showed prophylactic fixation of all 26 patients ($781,508) would save $353,067 compared to treating the 13 who fractured again ($1,134,575). CONCLUSIONS:A novel matrix was developed that accurately predicted 5-year second hip fracture and mortality risk. Prophylactic fixation in low-mortality, high-risk patients may reduce costs and prevent future fractures. [Tool available: https://sttgmacom.wpcomstaging.com/predicting-risk-of-second-hip-fractures/]. LEVEL OF EVIDENCE/METHODS:Level III Diagnostic.
PMID: 40853342
ISSN: 1531-2291
CID: 5909912
Does the addition of demineralized bone matrix to fixation of acute comminuted clavicle fractures affect healing outcomes?
Linker, Jacob A; Ganta, Abhishek; Konda, Sanjit R; Egol, Kenneth A
PURPOSE/OBJECTIVE:To assess the healing outcomes of patients who sustained a comminuted clavicle fracture and underwent operative fixation with or without the addition of demineralized bone matrix (DBM). METHODS:A total of 271 comminuted midshaft clavicle fractures that presented to our hospital system and underwent operative fixation with a plate and screw construct were retrospectively reviewed. Data collected include patient demographics, initial injury information, and use of demineralized bone matrix during surgery to enhance bone healing. Patients were grouped based on whether or not their fixation was augmented with DBM. Fracture-related infection (FRI), lack of fracture healing, and the need for revision fracture surgery were reviewed. Adhesive capsulitis of the shoulder and screw back out were categorized as "minor complications." Clinical healing was defined as non-tenderness about the fracture site, and radiographic healing was defined as presence of bridging callus and lack of fracture line on X-ray. Chi-square, T-test, and linear regression analysis were used to determine any significant differences between cohorts. RESULTS:Sixty-nine patients had DBM used in their repair, and 202 patients did not. Cohorts had a similar follow-up (range: 6-18 months). There were no differences in patient demographics or fracture pattern between the two groups (P > 0.05 for all). There were no differences in major and minor complications; however, the cohort treated with DBM had shorter time to radiographic healing, confirmed with regression analysis (P < 0.05). CONCLUSION/CONCLUSIONS:Augmentation of midshaft clavicle fracture constructs with DBM was associated with quicker radiographic healing.
PMID: 40879830
ISSN: 1432-1068
CID: 5910732
Triceps-sparing versus triceps-splitting approaches for OTA 12A-C and 13A2-3 distal-third humeral shaft fractures have similar 1 year functional outcomes
Ganta, Abhishek; Goldstein, Amelia; Lezak, Bradley; Campbell, Hillary; Egol, Kenneth; Konda, Sanjit
PURPOSE/OBJECTIVE:To compare functional outcomes of distal third humeral shaft fractures (OTA 12A-C and 13A2-3) treated with either triceps-splitting or triceps-sparing surgical approach. Secondarily, the purpose was to compare healing and complication rates between the two surgical approaches. METHOD/METHODS:A retrospective review of a prospectively collected humeral shaft registry was performed from 01/2018-12/2024. Inclusion criteria was: age > 18yo, OTA 12A-C or 13A2-3 distal third humeral shaft fracture, either triceps-splitting or triceps-sparing surgical approach, and minimum 1-year follow-up. The primary outcome was 1-year postoperative functional status measured using the Disabilities of the Arm, Shoulder, and Hand (DASH) score. Secondary outcomes measures included surgical time, radiographic union times, union rates, iatrogenic nerve injury, fracture related infection, hardware failure, reoperation, and documented range of motion (ROM) at last follow-up. Univariate analysis with two-tailed Student's t-tests and chi-square tests was used to compare demographics, injury and surgical characteristics. RESULT/RESULTS:A total of 39 patients met inclusion criteria: 27 (69.2%) underwent a triceps-splitting approach and 12 (30.8%) a triceps-sparing approach. There were no significant differences in baseline demographics. At final follow-up, functional outcomes were comparable. DASH scores were similar between groups (7.7 ± 13.8 vs 7.0 ± 9.0, p = 0.89), as were fracture healing times (5.5 ± 2.2 vs 6.1 ± 3.6 months, p = 0.63), with all fractures achieving union. Surgical duration was shorter in the splitting group (83 ± 42 vs 103 ± 52 min, p = 0.26), though not statistically significant. No hardware-related complications were reported. Two radial nerve palsies (7.6%) occurred in the splitting group, while one postoperative infection (8.3%) occurred in the sparing group (all p > 0.05). Elbow range of motion was similar. Mean flexion was 137.9 ± 10.0° in the splitting group vs 131.3 ± 30.0° in the sparing group (p = 0.47); mean extension was 2.3 ± 4.7° vs 4.6 ± 5.5°, respectively (p = 0.21). CONCLUSION/CONCLUSIONS:There is no difference in 1-year functional outcomes as measured by the DASH score between the triceps-splitting versus triceps-sparing approach for surgical fixation of the OTA 12A-C and 13A2-3 distal third humeral shaft fractures. Either surgical approach is viable for distal third humeral shaft fractures. LEVEL OF EVIDENCE/METHODS:Level III.
PMID: 40721679
ISSN: 1432-1068
CID: 5903132
Factors associated with decline in ambulatory ability following intramedullary nailing of 42A-C diaphyseal tibia fractures
Lashgari, Alexander M; Esper, Garret; Ganta, Abhishek; Egol, Kenneth A; Konda, Sanjit
BACKGROUND/UNASSIGNED:The purpose of this study was to examine factors that were associated with a decline in functional ambulatory status following fractures of the tibial diaphysis. METHODS/UNASSIGNED:A retrospective review of an IRB-approved tibial diaphysis fracture database from 2012 to 2024 was conducted. Inclusion criteria were age ≥18, isolated OTA 42A-C tibia fracture treated with an intramedullary nail, and minimum 12 months follow-up. Demographics, injury, and surgical information were collected. Functional ambulatory status was measured at routine follow up intervals by the Functional Ambulatory Category (FAC) score, a six-point scale where zero represents non-ambulation and five represents normal ambulatory ability. Univariate analysis was performed using Student's T-tests and Chi-squared tests. A backwards stepwise multivariate logistic regression analysis was performed to determine factors that were independently associated with a decline in FAC score (SPSS version 29, Armonk, NY). RESULTS/UNASSIGNED:289 patients, with a mean follow up time of 15.04 ± 6.18 months, were included in the analysis with a mean age of 43.24 ± 16.22 years, body mass index of 27.19 ± 6.30, and age-unadjusted Charlson Comorbidity Index of 0.18 ± 0.54. 39.1 % of patients were female, 28.0 % patients sustained open fractures, and 52.6 % sustained high energy injuries. The logistic regression demonstrated that older age (OR = 1.04 p < .001), higher BMI (OR = 1.06 p = .024), high-energy mechanism (OR = 3.18 p = .003), nonunion (OR = 3.66, p = .005), and concomitant lower extremity fractures (OR = 4.47 p = 002), were risk factors for a decrease in final FAC score. The AUROC of the logistic regression equation was 0.787 indicating a moderate ability to discriminate between patients that will experience a loss in functional ambulatory ability and those who will not. CONCLUSION/UNASSIGNED:This study suggests that concomitant lower extremity injuries, increased age, increased BMI, high-energy mechanisms, and nonunion are risk factors that are associated with a decline in ambulatory capacity following diaphyseal tibia fractures.
PMCID:12274951
PMID: 40687745
ISSN: 0976-5662
CID: 5901142
Ready for discharge? Factors associated with prolonged length of stay following geriatric hip fracture
Pettit, Christopher; Herbosa, Carolyn; Ganta, Abhishek; Egol, Kenneth; Konda, Sanjit
PURPOSE/OBJECTIVE:To identify factors associated with prolonged length of stay following geriatric hip fractures. METHODS:A single-center retrospective study of a consecutive series of geriatric (age > 65) hip fractures between 10/1/14 and 11/1/23 was performed. Patient demographics, injury/surgery characteristics, and inpatient complications were reviewed. Patients who died during hospitalization were excluded. Patients were cohorted into "average" LOS (nLOS) and "prolonged" LOS (pLOS); pLOS was defined as 1 standard deviation above the mean LOS. Cohort variables were compared using standard statistical tests. Multivariable logistic regression was used to isolate covariates that were independently associated with pLOS while controlling for confounders. RESULTS:A total of 3383 patients were identified. Average LOS was 6.38 days (S.D. = 4.24 days), and prolonged LOS was 10.62 days. The pLOS cohort was sicker and less functionally independent at baseline. The pLOS cohort had a more complicated hospital course with a 6 × increase in major complications and 2 × increase in minor complications. The demographic characteristic associated the most to pLOS was male gender. The injury/surgery characteristic contributing the most to pLOS was time from admission to surgery. The complication contributing the most to pLOS was new-onset stroke. CONCLUSION/CONCLUSIONS:Multiple demographic and outcome factors are associated with pLOS in geriatric hip fractures. While demographics cannot be changed, teams should focus on modifiable factors such as reducing time to surgery and identification, prevention, and treatment of perioperative complications, most importantly stroke and pneumonia, to prevent delays in discharge following hip fracture in the elderly population. LEVEL OF EVIDENCE/METHODS:Level IV.
PMID: 40545513
ISSN: 1432-1068
CID: 5874642