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Evaluation of Subchondral Bone Marrow Lipids of Acute Anterior Cruciate Ligament (ACL)-Injured Patients at 3 T
Wang, Ligong; Salibi, Nouha; Chang, Gregory; Bencardino, Jenny T; Babb, James S; Rokito, Andrew; Jazrawi, Laith; Sherman, Orrin; Regatte, Ravinder R
RATIONALE AND OBJECTIVES: The objectives of this study were to investigate the changes in compartment-specific subchondral bone marrow lipids of femoral-tibial bone in acute anterior cruciate ligament (ACL)-injured patients compared to that of healthy volunteers and patients with osteoarthritis (OA) (Kellgren-Lawrence [KL] grade 2-3). MATERIALS AND METHODS: A total of 55 subjects were recruited in the study and subdivided into three subgroups: 17 healthy controls (4 females, 13 males; mean age = 41 +/- 16, age range 24-78 years), 17 patients with acute ACL injury (3 females, 14 males; mean age = 30 +/- 11, age range 18-61 years), and 21 patients with KL2-3 OA (12 females, 9 males; mean age = 65 +/- 12, age range 44-89 years). Routine clinical proton density-weighted fast spin echo images in sagittal (without fat saturation), axial, and coronal (fat saturation) planes were acquired on a 3 T clinical scanner for cartilage morphology using Whole-Organ Magnetic Resonance Imaging Score grading. A voxel of 10 x 10 x 10 mm3 was positioned in the medial and lateral compartments of the tibia and femur for proton magnetic resonance spectroscopy measurements using the single voxel stimulated echo acquisition mode pulse sequence. All proton magnetic resonance data were processed with Java-based magnetic resonance user interface. Wilcoxon rank sum test and mixed model two-way analysis of variance were performed to determine significant differences between different compartments and examine the effect of ACL injury, OA grade and compartment, and their interactions. RESULTS: The index of unsaturation in lateral tibial compartment in ACL-injured patients was significantly higher (P < .05) than all compartments except lateral femoral in patients with KL2-3 OA. Significantly lower values (P < .05) were also identified in saturated lipids at 2.03 ppm in all compartments in ACL-injured patients than those of all compartments in patients with KL2-3 OA. CONCLUSIONS: The preliminary results suggest that the indices of unsaturation in the lateral tibial compartment and the peaks of saturated lipids at 1.3 and 2.03 ppm in medial tibial compartment may be clinically useful to characterize subchondral bone marrow among healthy controls, acute ACL-injured patients, and patients with OA.
PMCID:4037703
PMID: 24717549
ISSN: 1076-6332
CID: 895832
Current trends in the management of recurrent anterior shoulder instability
Rossy, William H; Cieslak, Kristina; Uquillas, Carlos A; Rokito, Andrew
The glenohumeral joint is innately complex and comprised of both static and dynamic stabilizers. Anterior glenohumeral instability has been estimated to have an incidence of 11.2 cases per 100,000 persons and typically follows a traumatic injury. Although there are specific instances when conservative management is advocated, a majority of these patients are treated with operative stabilization. Recent advancements in arthroscopy have created a shift from the traditional open stabilization procedures towards more minimally invasive arthroscopic stabilization procedures. This comprehensive review will summarize current concepts involved in evaluating patients with anterior glenohumeral instability and specifically focus on those patients who suffer from recurrent instability.
PMID: 25429389
ISSN: 2328-5273
CID: 2689272
The rising incidence of rotator cuff repairs
Ensor, Kelsey L; Kwon, Young W; Dibeneditto, Michael R; Zuckerman, Joseph D; Rokito, Andrew S
BACKGROUND: Rotator cuff repairs (RCRs) have become increasingly common. Several studies have shown variation in the indications for this procedure. We chose to track the incidence of RCRs in New York State (NYS) from 1995 to 2009. We hypothesized that after the introduction of the Current Procedural Terminology (CPT) code 29827 for arthroscopic RCR, there would be a significant increase in the rate of RCRs performed in NYS. MATERIALS AND METHODS: The NYS Department of Health's Statewide Planning and Research Cooperative System (SPARCS) database was queried for reported RCRs between the years 1995 and 2009. Using the International Classification of Diseases, Ninth Revision, Clinical Modification procedural code 83.63 and CPT codes 23410, 23412, 23420, and 29827, we collected and analyzed data on RCR procedures. RESULTS: A total of 168,780 RCRs were performed in NYS from 1995 to 2009. In 1995, the population incidence of RCRs was 23.5 per 100,000. In comparison, in 2009, the population incidence was 83.1 per 100,000, an increase of 238% (P < .0001). The percentage of individuals aged between 45 and 65 years undergoing RCR increased from 53.0% to 64.2% during this same period. CONCLUSIONS: There has been a notable increase in the volume of RCRs performed in NYS. In addition, after the introduction of CPT code 29827 in 2003, the increase in the incidence of RCRs became significantly more pronounced.
PMID: 23466172
ISSN: 1058-2746
CID: 590302
Authors' response [Letter]
Wasserman, Bradley R; Pettrone, Sarah; Jazrawi, Laith M; Zuckerman, Joseph D; Rokito, Andrew S
PMID: 24199231
ISSN: 0363-5465
CID: 833182
Accuracy of acromioclavicular joint injections: letter to the editor [Letter]
Sabeti, Manuel; Wasserman, Bradley R; Pettrone, Sarah; Jazrawi, Laith M; Zuckerman, Joseph D; Rokito, Andrew S
PMID: 24077749
ISSN: 0363-5465
CID: 590282
Accuracy of acromioclavicular joint injections
Wasserman, Bradley R; Pettrone, Sarah; Jazrawi, Laith M; Zuckerman, Joseph D; Rokito, Andrew S
BACKGROUND: Injection to the acromioclavicular (AC) joint can be both diagnostic and therapeutic. PURPOSE: The purpose of this study was to evaluate the accuracy of in vivo AC joint injections. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Thirty patients with pain localized to the AC joint were injected with 1 mL of 1% lidocaine and 0.5 mL of radiographic contrast material (Isovue). Radiographs of the AC joint were taken after the injection. Each radiograph was reviewed by a musculoskeletal radiologist and graded as intra-articular, extra-articular, or partially intra-articular. RESULTS: Of the 30 injections performed, 13 (43.3%) were intra-articular, 7 (23.3%) were partially articular, and 10 (33.3%) were extra-articular. When the intra-articular and the partially articular groups were combined, 20 patients (66.7%) had some contrast dye in the AC joint. CONCLUSION: This study demonstrates that despite the relatively superficial location of the AC joint, the clinical accuracy of AC joint injections remains relatively low.
PMID: 23193147
ISSN: 0363-5465
CID: 214962
Functional outcomes of anterior cruciate ligament reconstruction with tibialis anterior allograft
Shybut, Theodore B; Pahk, Brian; Hall, Gregory; Meislin, Robert J; Rokito, Andrew S; Rosen, Jeffrey; Jazrawi, Laith M; Sherman, Orrin H
Background: Allografts offer potential advantages over autografts in anterior cruciate ligament reconstruction (ACLR), including the absence of donor site morbidity, shorter operative times, improved cosmesis, and easier rehabilitation. There is limited and conflicting outcome data for ACLR with tibialis anterior allograft. The purpose of this study was to evaluate the functional outcomes of ACLR with tibialis anterior allograft. Methods:We retrospectively evaluated primary ACL reconstructions using tibialis anterior allograft between January 2004 and December 2006. Clinical outcomes were measured by KT-1000 arthrometry, and International Knee Documentation Committee (IKDC), Lysholm, and Tegner scores. Results: 19 patients were available for follow-up at a mean of 2.7 years (range: 2.0 to 3.2). One patient experienced a traumatic re-rupture that required revision and another patient was advised to undergo revision reconstruction for a failed graft. Based on IKDC and Lysholm scoring, 12 patients (63%) had good or excellent results, 4 (21%) patients had fair results, and 3 (16%) patients had poor results. The mean side-to-side difference was 2.7mm (0 to 8.2) and the mean decrease in Tegner activity level was 1.4 (0 to 6). Conclusion:An alarming number of patients demonstrated residual laxity after ACL reconstruction with tibialis anterior allograft. We recommend against using tibialis anterior allograft as a first choice graft for high demand patients.
PMID: 24032615
ISSN: 2328-4633
CID: 590292
Operative management of acromioclavicular joint injuries: Indications, techniques, and outcomes
Chapter by: Rokito, A; Schubkegel, TA; Epstein, DM
in: Disorders of the Shoulder: Diagnosis and Management: Shoulder Trauma by
pp. 226-244
ISBN: 9781469837864
CID: 2170872
The rising incidence of arthroscopic superior labrum anterior and posterior (SLAP) repairs
Onyekwelu, Ikemefuna; Khatib, Omar; Zuckerman, Joseph D; Rokito, Andrew S; Kwon, Young W
BACKGROUND: Superior labrum anterior-posterior (SLAP) lesions of the shoulder that require surgical repair are relatively uncommon. However, recent observations suggest that there may be a rise in the incidence of SLAP lesion repair. MATERIALS AND METHODS: The Statewide Planning and Research Cooperative Systems (SPARCS) database from the New York State Department of Health was used to acquire data for all outpatient ambulatory surgery procedures that were performed in New York State from 2002 to 2010. The data were reviewed and analyzed to compare the incidence of arthroscopic SLAP lesion repairs relative to other outpatient surgical procedures. RESULTS: Within New York State, from 2002 to 2010, the number of all ambulatory surgical procedures increased 55%, from 1,411,633 to 2,189,991. Correspondingly, the number of ambulatory orthopedic procedures increased 135%, from 118,126 to 278,136. In comparison, the number of arthroscopic SLAP repairs increased 464%, from 765 to 4,313 (P < .0001). This represented a population-based incidence of 4.0/100,000 in 2002 and 22.3/100,000 in 2010. The mean age of patients undergoing arthroscopic SLAP repair in 2002 was 37 +/- 14 years. The mean age in 2010 was 40 +/- 14 years (P < .0001). CONCLUSIONS: The data suggest a substantial increase in the number of arthroscopic SLAP repairs that is significantly more rapid than the rising rate of outpatient orthopedic surgical procedures. In addition, there is a significant increase in the age of patients who are being treated with arthroscopic SLAP repairs.
PMID: 22608836
ISSN: 1058-2746
CID: 167507
Anatomic variants and pitfalls of the labrum, glenoid cartilage, and glenohumeral ligaments
Dunham, Kevin S; Bencardino, Jenny T; Rokito, Andrew S
Magnetic resonance (MR) imaging is the primary diagnostic imaging modality for the evaluation of patients with suspected internal derangement of the shoulder joint. Awareness and understanding of the complex anatomy of the shoulder articulation and the ability to recognize normal anatomic variants and potential imaging pitfalls are critical to accurate interpretation of conventional and arthrographic MR imaging studies. This review discusses the normal anatomy and anatomic variants of the glenoid labrum, articular cartilage, and glenohumeral ligaments. An improved understanding of normal anatomy, biomechanics, and variants will help to avoid potential pitfalls in the interpretation of noncontrast and arthrographic shoulder MR imaging examinations.
PMID: 22469401
ISSN: 1064-9689
CID: 163584