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Free Tissue Transfer with Distraction Osteogenesis and Masquelet Technique Is Effective for Limb Salvage in Patients with Gustilo Type IIIB Open Fractures

Abdou, Salma A; Stranix, John T; Daar, David A; Mehta, Devan D; McLaurin, Toni; Tejwani, Nirmal; Saadeh, Pierre B; Levine, Jamie P; Leucht, Philipp; Thanik, Vishal D
Osteocutaneous reconstruction can be challenging because of concomitant injuries and limited donor sites. There is a paucity of data on limb salvage outcomes following combined soft-tissue reconstruction and bone transport or Masquelet procedures. The authors reviewed a consecutive series of open tibia fracture patients undergoing soft-tissue reconstruction with either distraction osteogenesis or Masquelet technique. Endpoints were perioperative flap complications and bone union. Fourteen patients with Gustilo type IIIB open tibia fractures were included. Half of the group received muscle flaps and the remaining half received fasciocutaneous flaps. Ten patients (71.4 percent) underwent distraction osteogenesis and the remaining patients underwent Masquelet technique. Average bone gap length was 65.7 ± 31.3 mm (range, 20 to 120 mm). In the bone transport group, the average external fixation duration was 245 days (range, 47 to 686 days). In the Masquelet group, the average duration of the first stage of this two-stage procedure (i.e., time from cement spacer placement to bone grafting) was 95 days (range, 42 to 181 days). Bone union rate, as determined by radiographic evidence, was 85.7 percent. There was one complete flap failure (7.1 percent). One patient underwent below-knee amputation after failing bone transport and developing chronic osteomyelitis and subsequent infected nonunion. Our case series demonstrates that nonosteocutaneous flap methods of limb reconstruction are a viable option in patients with segmental long bone defects, with a bone union rate of 85 percent and a limb salvage rate over 90 percent in patients with Gustilo type IIIB fractures. CLINICAL QUESTION/LEVEL OF EVIDENCE:: Therapeutic, IV.
PMID: 32221236
ISSN: 1529-4242
CID: 4369902

Complex Proximal Tibia Fractures: Workup, Surgical Approaches, and Definitive Treatment Options

Tejwani, Nirmal C; Archdeacon, Michael; Harvey, Edward; Shannon, Steven F; McAlister, Ian; Sciadini, Marcus F
Proximal tibia fractures including intra-articular plateau fractures are complex injuries that benefit from an algorithmic approach in terms of treatment to optimize outcomes and minimize complications. Certainly, nonsurgical treatment will be an option for some injuries; however, this chapter will focus on those injuries best addressed with surgicalsurgical treatment. Indications for surgical treatment include joint incongruity, joint instability and limb malalignment. In regard to surgical treatment, important considerations include appropriate management of the soft-tissue envelope, staged provisional reduction and stabilization versus immediate definitive fixation, single versus multiple surgical approaches, unilateral versus bicondylar fixation, and treatment of concomitant fracture-dislocation. This chapter describes surgical approaches to the proximal tibia ranging from the standard anterolateral to complex dual approaches or posterior approaches. Soft-tissue management becomes important due to the high-energy nature of these injuries with trauma both at the time of injury and then the surgical insult. Learning to identify and minimize these risks as well as addressing the soft-tissue defects that may require treatment is highlighted. Implant selection and fixation options for bicondylar plateau fractures will be discussed. Finally, use of nails, especially suprapatellar nails for proximal extra-articular proximal tibia fractures is described.
PMID: 32017745
ISSN: 0065-6895
CID: 4300082

High-energy Lateral Compression Type 1 Injuries of the Pelvis: A Spectrum of Injury

Tejwani, Nirmal; Stevens, Nicole M; Ganta, Abhishek
Lateral compression type 1 pelvic fractures comprise a spectrum of injuries of varying stability. The clinician should be cognizant of signs and symptoms of instability including complete sacral fractures, bilateral ramus fractures, displacement greater than 1 cm, high-energy mechanism, and inability to bear weight. Management of these injuries is controversial, but the clinician should consider examination under anesthesia and potentially surgical stabilization.
PMID: 31425321
ISSN: 1940-5480
CID: 4046592

It's All About the Timing: When Do I Take This Injury to the Operating Room?

Tejwani, Nirmal C; Nork, Sean; Kubiak, Erik N; Podolnick, Jeremy; Wolinsky, Philip R
Over time, what was considered urgent or emergent in orthopaedic trauma has been revisited, and as awareness of factors associated with outcomes has increased, priorities have changed. There are multiple procedures performed urgently in the belief that early intervention allowed for better outcomes for the injury and the patient. Classic examples of conditions for which urgent intervention has been implemented include open fractures, femoral neck fractures in the young adult, talus fractures, and compartment syndrome. All of these conditions are considered nonurgent except for compartment syndrome, which requires urgent and timely intervention. Studies have demonstrated that these injuries need to be managed in a timely fashion but not necessarily in the middle of the night. Outcomes can be improved by measures such as early antibiotic administration for open fractures, closed reduction of talus fracture-dislocations, and anatomic reduction of femoral neck fractures. These measures are more important and useful than an emergent trip to the operating room by inexperienced surgeons with staff who may be unprepared. Orthopaedic surgeons should be familiar with open fractures and the timing of irrigation and débridement, the relative urgency of managing talus fractures, and the need for immediate reduction and fixation of femoral neck fractures. For each of these injuries, factors other than timing that affect outcomes will be described. Finally, the emergent nature of diagnosis and management of compartment syndrome must also be understood.
PMID: 32032033
ISSN: 0065-6895
CID: 4300822

Tibial Shaft Fractures in Workers Compensation and No-Fault Insurance Is There a Difference in Resource Utilization?

Boylan, Matthew R; Suchman, Kelly I; Bosco, Joseph A; Tejwani, Nirmal C
BACKGROUND:Workers Compensation claims have been previously associated with inferior clinical outcomes. However, variation in inpatient stays for orthopedic trauma injuries according to insurance type has not been previously examined. METHODS:We investigated the differences according to insurance for tibial shaft fractures in regard to length of stay and disposition. Using the New York SPARCS database, we identified 1,856 adult non-elderly patients with an isolated tibial shaft fracture who underwent surgery. Patients were stratified by insurance type, including private, Medicaid, Workers Compensation, and no-fault, which covers medical expenses related to automobile or pedestrian accidents. RESULTS:Compared to private insurance (mean: 2.7 days), length of stay was longer for no-fault (mean: 3.9 days; adjusted difference +33%, p < 0.001) and Medicaid (mean: 3.5 days; adjusted difference +22%, p < 0.001), but not significantly different for Workers Compensation (mean: 3.5 days; adjusted difference +4%, p = 0.474). Compared to private insurance (rate: 3.5%), disposition to a facility was significantly higher for no-fault (rate: 10.1%; adjusted odds ratio [OR] = 3.3, p < 0.001) and Medicaid (rate: 7.6%; OR = 2.2, p = 0.003), but was not significantly different for Workers Compensation (rate: 6.3%; OR = 1.8, p = 0.129). CONCLUSIONS:Patients with no-fault insurance, but not Workers Compensation, are subject to longer hospital stays and are more likely to be discharged to a facility following operative fixation of an isolated tibial shaft fracture. These findings suggest that financial, social, and legal factors influence medical care for patients involved in automobile accidents with no-fault insurance.
PMID: 31487486
ISSN: 2328-5273
CID: 4067622

Post-operative Orthopedic Infection with Monomicrobial Leclercia adecarboxylata: A Case Report and Review of the Literature

Mayfield, Cory K; Haglin, Jack M; Konda, Sanjit R; Tejwani, Nirmal C; Egol, Kenneth A
CASE/METHODS:An 65-year-old immunocompetent female developed a Leclercia adecarboxylata infection following the repair of closed olecranon fracture. L. adecarboxylata is associated with polymicrobial infections, infections in immunocompromised patients and penetrating or open wounds. Following speciation, intravenous ceftriaxone was started. Two weeks later, the patient presented with leukopenia and neutropenia. Per infectious disease recommendations, the patient was switched to intravenous ertapenem with resolution of both infection and neutropenia. The olecranon fracture went on to heal fully. CONCLUSIONS:This case describes a rare postoperative monomicrobial infection with L. adecarboxylata in an immunocompetent host following musculoskeletal trauma and identifies L. adecarboxylata as a potential emerging hospital-acquired pathogen following orthopedic surgery.
PMID: 31343997
ISSN: 2160-3251
CID: 3987462

Influence of bone lesion location on femoral bone strength assessed by MRI-based finite-element modeling

Rajapakse, Chamith S; Gupta, Nishtha; Evans, Marissa; Alizai, Hamza; Shukurova, Malika; Hong, Abigail L; Cruickshank, Nicholas J; Tejwani, Nirmal; Egol, Kenneth; Honig, Stephen; Chang, Gregory
Currently, clinical determination of pathologic fracture risk in the hip is conducted using measures of defect size and shape in the stance loading condition. However, these measures often do not consider how changing lesion locations or how various loading conditions impact bone strength. The goal of this study was to determine the impact of defect location on bone strength parameters in both the sideways fall and stance-loading conditions. We recruited 20 female subjects aged 48-77 years for this study and performed MRI of the proximal femur. Using these images, we simulated 10-mm pathologic defects in greater trochanter, superior, middle, and inferior femoral head, superior, middle, and inferior femoral neck, and lateral, middle, and medial proximal diaphysis to determine the effect of defect location on change in bone strength by performing finite element analysis. We compared the effect of each osteolytic lesion on bone stiffness, strength, resilience, and toughness. For the sideways fall loading, defects in the inferior femoral head (12.21%) and in the greater trochanter (6.43%) resulted in the greatest overall reduction in bone strength. For the stance loading, defects in the mid femoral head (-7.91%) and superior femoral head (-7.82%) resulted in the greatest overall reduction in bone strength. Changes in stiffness, yield force, ultimate force, resilience, and toughness were not found to be significantly correlated between the sideways fall and stance-loading for the majority of defect locations, suggesting that calculations based on the stance-loading condition are not predictive of the change in bone strength experienced in the sideways fall condition. While stiffness was significantly related to yield force (R2 > 0.82), overall force (R2 > 0.59), and resilience (R2 > 0.55), in both, the stance-loading and sideways fall conditions for most defect locations, stiffness was not significantly related to toughness. Therefore, structure-dependent measure such as stiffness may not fully explain the post-yield measures, which depend on material failure properties. The data showed that MRI-based models have the sensitivity to determine the effect of pathologic lesions on bone strength.
PMID: 30851438
ISSN: 1873-2763
CID: 3747652

Day of Admission is Associated With Variation in Geriatric Hip Fracture Care

Boylan, Matthew R; Riesgo, Aldo M; Paulino, Carl B; Tejwani, Nirmal C
INTRODUCTION/BACKGROUND:The transition to bundled payment reimbursement for geriatric hip fractures has incentivized the identification of avoidable inefficiencies in the cost and quality of care. Although a "weekend effect" has been described with regard to hip fracture mortality, measures of efficiency according to the day of hip fracture admission are currently unclear. METHODS:We identified 62,303 patients aged 65 years or older with a primary diagnosis of femoral neck or intertrochanteric hip fracture in the New York Statewide Planning and Research Cooperative System between 2009 and 2014. Outcome measures included preoperative delay, postoperative length of stay (LOS), and cost of admission. RESULTS:Preoperative delay was longer for weekend admissions, but shorter for admissions on Wednesday, Thursday, and Friday. Postoperative LOS was longer for admissions on Tuesday, Wednesday, and Thursday. Discharge rates varied considerably according to the day of admission, ranging from 12% to 43% by hospital day 4 and 53% to 72% by hospital day 6. No differences in cost according to day of admission were found once preoperative delay and postoperative LOS were accounted for. DISCUSSION/CONCLUSIONS:Notable variation exists in hospitalizations for geriatric hip fracture depending on the day of admission. Our data suggest the presence of a weekend effect, in which changes in staffing of surgical, medical, and ancillary services lead to increased waiting times for surgery for new admissions and delays in discharge of early- and mid-week admissions. LEVEL OF EVIDENCE/METHODS:Level III, retrospective study.
PMID: 30247307
ISSN: 1940-5480
CID: 3313992

Is Patient Satisfaction Associated with Objective Measures of Geriatric Hip Fracture Care?

Boylan, Matthew R; Riesgo, Aldo M; Paulino, Carl B; Tejwani, Nirmal C
BACKGROUND:Patient satisfaction is publicly reported and used as a subjective measure of quality of care in alternative payment reimbursement models. In this study, we evaluated the association between patient satisfaction scores and objective measures of geriatric hip fracture care. Therefore, according to patient satisfaction score, we investigated the differences for geriatric hip fracture admissions in regard to 1. surgical delay during the index admission and 2. mortality within 1 year. METHODS:We identified 65,974 patients between the ages of 60 and 99 years with a primary diagnosis of femoral neck fracture in the New York Statewide Planning and Research Cooperative System database from 2009 to 2014. We evaluated patient satisfaction using annual hospital HCAHPS scores reported on Hospital Compare. Mixed effects regression models controlled for hospital and year of surgery as random effects variables and categorical age, sex, race, insurance, categorical Deyo score, fracture location, and surgical procedure as fixed effects variables. RESULTS:For high compared to low patient satisfaction hospitals, there were shorter surgical delays (β: -60%, 95% CI: -66% to -52%, p < 0.001) and a lower risk of 1-year mortality (OR: 0.86, 95% CI: 0.78 to 0.93, p < 0.001). For middle compared to low patient satisfaction hospitals, there were shorter surgical delays (β: -37%, 95% CI: -46% to -26%, p < 0.001), but no significant difference in 1-year mortality (OR: 0.94; 95% CI: 0.87 to 1.01; p = 0.091). CONCLUSIONS:Subjective quality, as measured by HCAHPS patient satisfaction scores, is associated with objective quality and clinical outcomes in geriatric hip fracture care. While these findings support the use of patient experience as a component of quality measurement, it remains unclear whether a superior patient experience in itself can increase the value of health care for patients in the form of superior clinical outcomes or if it will lead to increased strain on hospital resources and increase the cost of services, which would paradoxically decrease the value of care.
PMID: 31513510
ISSN: 2328-5273
CID: 4088302

Commonly Missed Injuries in the Patient with Polytrauma and the Orthopaedist's Role in the Tertiary Survey

Stevens, Nicole M; Tejwani, Nirmal
PMID: 30516717
ISSN: 2329-9185
CID: 3520712