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116


Systemic Treatment for Clinically Amyopathic Dermatomyositis at 4 Tertiary Care Centers

Pinard, Joanie; Femia, Alisa N; Roman, Michael; Alsarheed, Abeer; Joyce, Cara; Lin, Janice; Vleugels, Ruth Ann
PMCID:6459090
PMID: 30673076
ISSN: 2168-6084
CID: 4372222

Systemic sclerosis with malignant acanthosis nigricans in a patient with gastric adenocarcinoma [Case Report]

Nadelman, Daniel A; Orbuch, David; Sandigursky, Sabina; Femia, Alisa N
PMCID:6872833
PMID: 31768409
ISSN: 2352-5126
CID: 4215802

Pityriasis rubra pilaris: A study evaluating patient quality of life in 2 populations

Eastham, A Brooke; Tkachenko, Elizabeth Y; Femia, Alisa N; Pappas-Taffer, Lisa K; Rosenbach, Misha; Joyce, Cara J; Liu, Stephanie; Vleugels, Ruth Ann
PMID: 30710600
ISSN: 1097-6787
CID: 3989512

Clinical epidemiology and treatment of lichen planus: a retrospective review of two tertiary care centers

Schwager, Zachary; Stern, Marleigh; Cohen, Jeffrey; Femia, Alisa
PMID: 31004729
ISSN: 1097-6787
CID: 3810762

Assessment of Antimalarial Therapy in Patients Who Are Hypersensitive to Hydroxychloroquine

Riley, Kathryn; Schwager, Zachary; Stern, Marleigh; Vleugels, Ruth Ann; Femia, Alisa
PMID: 30758479
ISSN: 2168-6084
CID: 3656302

Advances in Cutaneous Lupus Erythematosus and Dermatomyositis: A report from the 4th International Conference on Cutaneous Lupus Erythematosus An ongoing need for international consensus and collaborations

Concha, Josef Symon S; Patsatsi, Aikaterini; Marshak-Rothstein, Ann; Liu, Ming-Lin; Sinha, Animesh A; Lee, Lela A; Merola, Joseph F; Jabbari, Ali; Gudjonsson, Johann E; Chasset, François; Jarrett, Paul; Chong, Benjamin; Arkin, Lisa; Fernandez, Anthony P; Caproni, Marzia; Greenberg, Steven A; Kim, Hee Joo; Pearson, David R; Femia, Alisa; Vleugels, Ruth Ann; Fiorentino, David; Fujimoto, Manabu; Wenzel, Joerg; Werth, Victoria P
PMID: 30243657
ISSN: 1523-1747
CID: 3313822

Correction to: MRI assessment of the thigh musculature in dermatomyositis and healthy subjects using diffusion tensor imaging, intravoxel incoherent motion and dynamic DTI [Correction]

Sigmund, E E; Baete, S H; Luo, T; Patel, K; Wang, D; Rossi, I; Duarte, A; Bruno, M; Mossa, D; Femia, A; Ramachandran, S; Stoffel, D; Babb, J S; Franks, A G; Bencardino, J
The original version of this article, published on 04 June 2018, unfortunately contained a mistake.
PMID: 29987417
ISSN: 1432-1084
CID: 3191822

Epidemiology and treatment of lichen planus: Experience of a tertiary medical center [Meeting Abstract]

Stern, M; Schwager, Z; Cohen, J; Femia, A
Background: Lichen Planus (LP) is a chronic idiopathic disorder of the skin, nails, and mucous membranes with a varied clinical presentation. This study describes the epidemiology and treatment of LP patients treated in a large tertiary medical center.
Method(s): This retrospective chart review identified 294 patients with biopsy-proven LP seen within the dermatology department at NYU Langone Medical Center from January 1, 2005, September 5, 2016. Patients were identified using ICD code-based queries (ICD-9 697.0, ICD-10 L43.0-L43.9). Demographic, physical examination, pathologic, laboratory, and treatment data were extracted.
Result(s): Of 294 participants, 65% were female. Fifty-five percent were white, 16% black, 12% South Asian, 10% Hispanic, and 6% Asian. Mean age at symptom-onset, presentation, and diagnosis was 46.7, 51, and 49.9 years, respectively. Initial misdiagnosis occurred in 15.6% of patients. Of individuals for whom physical examination was recorded (n = 282), 35.1% had documented mucosal involvement (59.6% oral only, 19.2% genital only, and 21.2% both oral and genital). Cutaneous involvement was seen in 69.5% of patients with mucosal involvement of only the oral cavity, compared with 36.8% with only genital involvement. Pruritus was the most common symptom (57.3%). Hepatitis C testing was performed in 38.3% of patients; 9.7% of those tested were positive. Sixty-seven percent were treated with topicals only and 27.5% received systemic therapy. In total, 20 systemic agents were used; prednisone was used most commonly, followed by cyclosporine and hydroxychloroquine. Of patients on systemic therapies, 28.4% required 2 or more systemic agents during their course.
Conclusion(s): This is the largest study to date to describe the epidemiology and treatment of lichen planus. Lichen planus is most common among women, has a mean age of onset of 46.7 years, and most commonly presents with pruritus. Mucosal involvement is present in 35.1% of individuals, most commonly involving the oral cavity. Patients with only oral involvement had a higher rate of cutaneous involvement than subjects with only genital involvement. The majority of patients did not receive hepatitis C testing, but 9.7% of those with test results were positive. Topical monotherapy was often insufficient, and 27.5% of patients required systemic therapy. Systemic therapy most commonly included the use of corticosteroids, although many required therapy with multiple systemic agents.
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EMBASE:2000995672
ISSN: 0190-9622
CID: 4385082

Generalized essential telangiectasia

Wiznia, Lauren E; Steuer, Alexa B; Penn, Lauren A; Meehan, Shane A; Femia, Alisa N
The pathophysiology of generalized essential telangiectasia is not well understood. Generalized essential telangiectasia is an uncommon disorder in which widespread telangiectasias of unknown cause develop without associated systemic or antecedent dermatologic disease. We report a case of generalized essential telangiectasia in an otherwise healthy 49-year-old man.
PMID: 30677795
ISSN: 1087-2108
CID: 3610002

Acquired immune deficiency syndrome-related epidemic Kaposi sarcoma

Steuer, Alexa B; Cohen, Jeffrey M; Christman, Mitalee P; Penn, Lauren A; Brinster, Nooshin; Femia, Alisa N
Kaposi sarcoma (KS) is a vascular neoplasm that is one of the most common human immunodeficiency virus (HIV)-related malignancies. We present the case of a 42-year-old man with a new diagnosis of HIV and acquired immune deficiency syndrome (AIDS)-related epidemic KS.
PMID: 30677797
ISSN: 1087-2108
CID: 3610022