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152


Robotic-assisted laparoscopic transection and repair of an obturator nerve during pelvic lymphadenectomy for endometrial cancer [Case Report]

Nezhat, Farr R; Chang-Jackson, Shao-Chun R; Acholonu, Uchenna C; Vetere, Patrick F
BACKGROUND:Obturator nerve injury may occur in gynecologic surgery, particularly in cases in which extensive pelvic sidewall retroperitoneal dissection is performed. The lack of tactile feedback from the robotic surgical system may contribute to obturator nerve injury. If surgical division occurs, microsurgical end-to-end anastomosis of the obturator nerve may be performed. CASE/METHODS:A 76-year-old woman with stage IA endometrial adenocarcinoma sustained a left obturator nerve transection during pelvic lymphadenectomy that was recognized immediately. Robotic-assisted laparoscopic repair was performed successfully, with the patient experiencing no residual neuropathy 6 months postoperatively. CONCLUSION/CONCLUSIONS:Robotic-assisted laparoscopic repair is feasible for the treatment of obturator nerve injury.
PMID: 22270439
ISSN: 1873-233x
CID: 5020342

Electrocautery-associated vascular injury during robotic-assisted surgery [Case Report]

Cormier, Beatrice; Nezhat, Farr; Sternchos, Jason; Sonoda, Yukio; Leitao, Mario M
BACKGROUND:The robotic surgical platform is increasingly used in gynecology and, similar to laparoscopy, it has risks of electrocautery-associated injury. CASE/METHODS:We present three cases of injury caused by failures of the monopolar scissors' insulating sheath while coagulation and cutting currents were set at 35 W. In case 1, an external iliac vein injury required blood transfusion and emergent laparotomy. In case 2, a full-thickness external iliac artery injury was repaired robotically. In case 3, a partial-thickness external iliac artery injury also was repaired robotically. CONCLUSION/CONCLUSIONS:Unintended electrosurgical arcs can occur from monopolar instruments. Insulation failure is a common finding in this type of injury. Surgeons should avoid excessive instrument collisions and should change the monopolar scissors' insulating sheath if there are any concerns of a defect in its integrity.
PMID: 22825276
ISSN: 1873-233x
CID: 5020352

Endometriosis: ancient disease, ancient treatments [Historical Article]

Nezhat, Camran; Nezhat, Farr; Nezhat, Ceana
PMID: 23084567
ISSN: 1556-5653
CID: 5020362

Leiomyoma recurrent at the cervical stump: report of two cases [Case Report]

Chu, Christine M; Acholonu, Uchenna C; Chang-Jackson, Shao-Chun R; Nezhat, Farr R
Although supracervical hysterectomy is an increasingly popular modality for surgical management of benign uterine conditions data exploring all of its consequences are still forth coming. This case report will discuss the scenario of leiomyoma recurrence at the cervical stump after supracervical hysterectomy. After supracervical hysterectomy, the remnant cervix has the potential for leiomyoma formation. Surgeons performing supracervical hysterectomy should be aware of this possible outcome.
PMID: 22196264
ISSN: 1553-4669
CID: 5020322

What is the role of lymphadenectomy in surgical management of patients with endometrial carcinoma?

Nezhat, Farr; Chang, Linus; Solima, Eugenio
The role of lymphadenectomy in the management of endometrial carcinoma remains controversial in gynecologic oncology. Comprehensive pelvic and paraaortic lymphadenectomy should be performed in patients with intermediate- and high-risk endometrial cancer.
PMID: 22244676
ISSN: 1553-4669
CID: 5020332

Laparoscopic splenectomy for isolated recurrent papillary serous ovarian carcinoma [Meeting Abstract]

Nezhat, F.; Sternchos, J.; Finger, T.; Halpern, D.
ISI:000303227600094
ISSN: 0090-8258
CID: 3726792

Laparoscopic Splenectomy for Isolated Recurrent Ovarian Cancer

Sternchos, J; Finger, T; Halpern, David; Nezhat, F
ORIGINAL:0013358
ISSN: 1553-4650
CID: 3726802

Laparoscopy for the management of early-stage endometrial cancer: from experimental to standard of care

Acholonu, Uchenna C Jr; Chang-Jackson, Shao-Chun R; Radjabi, A Reza; Nezhat, Farr R
We performed a search of PUBMED and MEDLINE for articles concerning surgical management of early stage endometrial cancer from 1950 to 2011. From the articles collected we extracted data such as estimated blood loss, operating room time, complications, conversion to laparotomy, and length of hospital stay. Forty-seven relevant sources were analyzed. The patients in the laparoscopy group had less blood loss, fewer complications, longer operating room times, and a shorter length of stay. Lymph node count was similar in both groups. Although obesity is not a contraindication to laparoscopy, it does lead to a higher conversion rate. Route of surgical treatment had no impact on recurrence or survival. Robotic surgery has significant advantages over laparotomy, but advantages over laparoscopy are not as distinct. Laparoscopic hysterectomy offers several advantages over laparotomy. These advantages relate to improvements in patient care with comparable clinical outcome. After careful analysis we believe laparoscopy should be the standard of care for surgical management of early stage endometrial cancer.
PMID: 22551760
ISSN: 1553-4669
CID: 2422182

Safety and efficacy of video laparoscopic surgical debulking of recurrent ovarian, fallopian tube, and primary peritoneal cancers

Nezhat, Farr R; Denoble, Shaghayegh M; Cho, Jennifer E; Brown, Douglas N; Soto, Enrique; Chuang, Linus; Gretz, Herbert; Saharia, Prakash
BACKGROUND AND OBJECTIVE: Studies on the role of laparoscopy in secondary or tertiary cytoreduction for recurrent ovarian cancer are limited. Our objective is to describe our preliminary experience with laparoscopic secondary/tertiary cytoreduction in patients with recurrent ovarian, fallopian, and primary peritoneal cancers. METHODS: This is a retrospective analysis of a prospective case series. Women with recurrent ovarian, fallopian tube, or primary peritoneal cancers deemed appropriate candidates for laparoscopic debulking by the primary surgeon(s) were recruited. The patients underwent exploratory video laparoscopy, biopsy, and laparoscopic secondary/tertiary cytoreduction between June 1999 and October 2009. Variables analyzed include stage, site of disease, extent of cytoreduction, operative time, blood loss, length of hospital stay, complications, and survival time. RESULTS: Twenty-three patients were recruited. Only one surgery involved conversion to laparotomy. Seventeen (77.3%) of the patients had stage IIIC disease at the time of their initial diagnosis, and 20 (90.9%) had laparotomy for primary debulking. Median blood loss was 75 mL, median operative time 200 min, and median hospital stay 2 d. No intraoperative complications occurred. One patient (4.5%) had postoperative ileus. Eighteen (81.8%) of the patients with recurrent disease were optimally cytoreduced to 1cm. Overall, 12 patients have no evidence of disease (NED), 6 are alive with disease (AWD), and 4 have died of disease (DOD), over a median follow-up of 14 mo. Median disease-free survival was 71.9 mo. CONCLUSIONS: In a well-selected population, laparoscopy is technically feasible and can be utilized to optimally cytoreduce patients with recurrent ovarian, fallopian, or primary peritoneal cancers.
PMCID:3558884
PMID: 23484556
ISSN: 1086-8089
CID: 2317162

Robotic assisted surgery in gynecology: current insights and future perspectives

Tinelli, Andrea; Malvasi, Antonio; Gustapane, Sarah; Buscarini, Maurizio; Gill, Indy S; Stark, Michael; Nezhat, Farr R; Mettler, Liselotte
To focus on the recent adoption, patents, experience, and future of Robotic assisted surgery (RAS) applications in gynecologic surgery, a computer aided and manual search for clinical and systematic reviews, randomized controlled trials, prospective observational studies, retrospective studies and case reports published between 1970 and January of 2011 has been performed. The use of RAS in gynecologic patients includes hysterectomy, myomectomy, tubal reanastomoses, radical hysterectomy, lymph node dissection, and sacrocolpopexies. Although individual studies vary, gynecological RAS is often associated with longer operating room time but similar clinical outcomes, decreased blood loss, and shorter hospital stay. RAS procedures on women have, however, their own limitations: the patented equipment is very large, bulky, and expensive, the staff must be trained specifically on draping and docking the instruments, the lack of surgical haptic feedback, a limited vaginal access, a limited specific instrumentation, and the need for larger port incisions requiring fascial closure. The RAS significantly facilitates gynecologic surgery, even if well-designed, prospective studies are needed to fully assess the value of this equipments in particular studies with well-defined clinical and long-term outcomes, including complications, cost, pain, return to normal activity, and quality of life. The future of robotic surgery in gynecology may be bright, but currently, caution is advisable and clinically meaningful long-term outcomes are needed. These recent patents, however, has exciting potential for future applications, especially in long-distance telesurgery and might change the paradigm of gynecologic surgery in the future.
PMID: 21517747
ISSN: 2212-4012
CID: 5020282