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Impact of half-time image acquisition with wide-beam reconstruction on the perfusion scores and diagnostic certainty of single-photon emission computed tomography [Meeting Abstract]
Druz, R; Phillips, LM; Rutkin, BJ; Boutis, LS
ISI:000207860500314
ISSN: 1520-765x
CID: 2581812
Mandatory diagnostic angiography for carotid artery stenosis prior to carotid artery intervention
Makaryus, Amgad N; Phillips, Lawrence M; Wright, Paul; Freeman, Jason; Green, Stephen J; Ong, Lawrence; Marchant, Donna
INTRODUCTION: Revascularization is an important strategy for reducing stroke risk in patients with severe carotid atherosclerosis. Magnetic resonance angiography (MRA) and/or carotid ultrasound have traditionally been used as the only diagnostic modalities prior to revascularization. Patients undergoing CEA frequently have no further assessments of carotid anatomy prior to surgery. Evaluation with carotid ultrasound and MRA can often overestimate the degree of stenosis. We sought to determine if noninvasive imaging was sufficient for determining whether a patient should be referred for carotid intervention. METHODS: We performed an analysis of 101 patients referred for carotid artery stenting (CAS). All patients had previously been evaluated with carotid ultrasound and 94% had undergone MRA as well. We sought to determine if noninvasive diagnostic imaging for carotid stenosis was sufficient to determine the necessity for endovascular intervention. RESULTS: Of the 101 patients referred for carotid intervention, 36 (36%) were shown to have <70% stenoses and did not require intervention. Of those who had significant disease, 49 (75%) underwent successful CAS, 15 (23%) underwent CEA, and 1 patient was treated medically for a total occlusion. Three of the 36 patients not requiring carotid intervention were found to have subclavian stenosis. Two (4%) of the patients undergoing CAS and 4 (27%) of the patients undergoing CEA had minor complications. No patients suffered a major stroke, MI, or death at follow-up. CONCLUSION: This analysis demonstrates that 36% of patients referred for endovascular intervention based on noninvasive imaging did not meet criteria by angiography. This emphasizes the need for carotid angiography prior to carotid intervention
PMID: 18973511
ISSN: 1540-8183
CID: 95316
Impact of Half-Time Image Acquisition with Wide-Beam Reconstruction on the Perfusion Scores and Diagnostic Certainty of Single-Photon Emission Computed Tomography: Comparison with Filtered Back-Projection [Meeting Abstract]
Druz, Regina S; Phillips, Lawrence M; Rutkin, Bruce J; Boutis, Loukas S
ISI:000262104504016
ISSN: 0009-7322
CID: 2581762
Myocardial perfusion imaging in patients with new-onset atrial fibrillation: Cardiac risk factors and coronary artery disease predict perfusion findings [Meeting Abstract]
Phillips, Lawrence M; Patel, Keyoor; Druz, Regina S
ISI:000244651801162
ISSN: 0735-1097
CID: 2581882
Coronary artery dissection during pregnancy treated with medical therapy [Case Report]
Phillips, Lawrence M; Makaryus, Amgad N; Beldner, Stuart; Spatz, Allison; Smith-Levitin, Michelle; Marchant, Donna
Spontaneous coronary artery dissection is a rare etiology of myocardial infarction with a higher noted incidence in pregnancy. The recognition and proper treatment of this condition affects patient outcomes. We report the case of a coronary artery dissection during a twin pregnancy involving the left anterior descending artery. Successful treatment with medical management was possible once spontaneous reperfusion had been achieved
PMID: 16628025
ISSN: 1061-5377
CID: 75569
Contrast echocardiography improves the diagnostic yield of transthoracic studies performed in the intensive care setting by novice sonographers
Makaryus, Amgad N; Zubrow, Michael E; Gillam, Linda D; Michelakis, Nickolaos; Phillips, Lawrence; Ahmed, Safi; Friedman, David; Sison, Cristina; Kort, Smadar; Rosman, David; Mangion, Judy R
BACKGROUND: Bedside portable echocardiography in the intensive care department (ICU) is technically difficult, but crucial for directing patient care. Prior studies have shown contrast echocardiography (CE) in the ICU clarifies left ventricular wall motion when performed by experienced sonographers (ESO). However, in most hospitals, ESO are unavailable around the clock, and less experienced cardiovascular fellows or trainees may be asked to perform these examinations. METHODS: Transthoracic echocardiograms were retrospectively evaluated by level III trained echocardiographers for 213 patients in the ICU. Most were performed to assess left ventricular function (65% or 139 of 213) and were scanned by cardiology fellows (70% or 149 of 213) with less than 3 months echocardiography experience. Contrast agent was used in 29% (62 of 213) of all patients. RESULTS: The conversion of suboptimal or diagnostically inadequate apical 4- and 2-chamber views to diagnostically adequate with contrast was statistically significant when performed by both cardiology fellows and ESO (Fischer exact test, P < .0002). CONCLUSIONS: CE is effective in improving the diagnostic yield of transthoracic echocardiographic ICU studies performed by both novice sonographers and ESO. Using cardiology fellows to perform CE in this setting can be appropriate, particularly in after-hour situations, when ESO are not always available and the clinical question is left ventricular function. Results also suggest cardiology fellows can easily learn CE
PMID: 15891758
ISSN: 0894-7317
CID: 56191