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ACR Appropriateness Criteria Shoulder Pain-Atraumatic
Small, Kirstin M; Adler, Ronald S; Shah, Shaan H; Roberts, Catherine C; Bencardino, Jenny T; Appel, Marc; Gyftopoulos, Soterios; Metter, Darlene F; Mintz, Douglas N; Morrison, William B; Subhas, Naveen; Thiele, Ralf; Towers, Jeffrey D; Tynus, Katherine M; Weissman, Barbara N; Yu, Joseph S; Kransdorf, Mark J
Shoulder pain is one of the most common reasons for musculoskeletal-related physician visits. Imaging plays an important role in identifying the specific cause of atraumatic shoulder pain. This review is divided into two parts. The first part provides a general discussion of various imaging modalities (radiographs, arthrography, nuclear medicine, ultrasound, CT, and MRI) and their usefulness in evaluating atraumatic shoulder pain. The second part focuses on the most appropriate imaging algorithms for specific shoulder conditions including: rotator cuff disorders, labral tear/instability, bursitis, adhesive capsulitis, biceps tendon abnormalities, postoperative rotator cuff tears, and neurogenic pain. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 30392607
ISSN: 1558-349x
CID: 3429262
Response to Nazarian et al regarding: "Cost-effectiveness of magnetic resonance imaging versus ultrasound for the detection of symptomatic full-thickness supraspinatus tendon tears" [Letter]
Gyftopoulos, Soterios; Guja, Kip E; Subhas, Naveen; Virk, Mandeep S; Gold, Heather T
PMID: 30093231
ISSN: 1532-6500
CID: 3226702
Qualitative Study to Understand Ordering of CT Angiography to Diagnose Pulmonary Embolism in the Emergency Room Setting
Gyftopoulos, Soterios; Smith, Silas W; Simon, Emma; Kuznetsova, Masha; Horwitz, Leora I; Makarov, Danil V
PURPOSE: To better understand the decision making behind the ordering of CT pulmonary angiography (CTPA) for the diagnosis of pulmonary embolism (PE) in the emergency department. METHODS: We conducted semistructured interviews with our institution's emergency medicine (EM) providers and radiologists who read CTPAs performed in the emergency department. We employed the Theoretical Domains Framework-a formal, structured approach used to better understand the motivations and beliefs of physicians surrounding a complex medical decision making-to categorize the themes that arose from our interviews. RESULTS: EM providers were identified as the main drivers of CTPA ordering. Both EM and radiologist groups perceived the radiologist's role as more limited. Experience- and gestalt-based heuristics were the most important factors driving this decision and more important, in many cases, than established algorithms for CTPA ordering. There were contrasting views on the value of d-dimer in the suspected PE workup, with EM providers finding this test less useful than radiologists. EM provider and radiologist suggestions for improving the appropriateness of CTPA ordering consisted of making this process more arduous and incorporating d-dimer tests and prediction rules into a decision support tool. CONCLUSION: EM providers were the main drivers of CTPA ordering, and there was a marginalized role for the radiologist. Experience- and gestalt-based heuristics were the main influencers of CTPA ordering. Our findings suggest that a more nuanced intervention than simply including a d-dimer and a prediction score in each preimaging workup may be necessary to curb overordering of CTPA in patients suspected of PE.
PMCID:5908756
PMID: 29055608
ISSN: 1558-349x
CID: 2757552
Automated Pulmonary Embolism Risk Classification and Guideline Adherence for Computed Tomography Pulmonary Angiography Ordering
Koziatek, Christian A; Simon, Emma; Horwitz, Leora I; Makarov, Danil V; Smith, Silas W; Jones, Simon; Gyftopoulos, Soterios; Swartz, Jordan L
BACKGROUND:The assessment of clinical guideline adherence for the evaluation of pulmonary embolism (PE) via computed tomography pulmonary angiography (CTPA) currently requires either labor-intensive, retrospective chart review or prospective collection of PE risk scores at the time of CTPA order. The recording of clinical data in a structured manner in the electronic health record (EHR) may make it possible to automate the calculation of a patient's PE risk classification and determine whether the CTPA order was guideline concordant. OBJECTIVES/OBJECTIVE:The objective of this study was to measure the performance of automated, structured-data-only versions of the Wells and revised Geneva risk scores in emergency department encounters during which a CTPA was ordered. The hypothesis was that such an automated method would classify a patient's PE risk with high accuracy compared to manual chart review. METHODS:We developed automated, structured-data-only versions of the Wells and revised Geneva risk scores to classify 212 emergency department (ED) encounters during which a CTPA was performed as "PE Likely" or "PE Unlikely." We then combined these classifications with D-dimer ordering data to assess each encounter as guideline concordant or discordant. The accuracy of these automated classifications and assessments of guideline concordance were determined by comparing them to classifications and concordance based on the complete Wells and revised Geneva scores derived via abstractor manual chart review. RESULTS:The automatically derived Wells and revised Geneva risk classifications were 91.5% and 92% accurate compared to the manually determined classifications, respectively. There was no statistically significant difference between guideline adherence calculated by the automated scores as compared to manual chart review (Wells: 70.8 vs. 75%, p = 0.33 | Revised Geneva: 65.6 vs. 66%, p = 0.92). CONCLUSION/CONCLUSIONS:The Wells and revised Geneva score risk classifications can be approximated with high accuracy using automated extraction of structured EHR data elements in patients who received a CTPA. Combining these automated scores with D-dimer ordering data allows for the automated assessment of clinical guideline adherence for CTPA ordering in the emergency department, without the burden of manual chart review.
PMCID:6133740
PMID: 29710413
ISSN: 1553-2712
CID: 3056432
Variation in Downstream Relative Costs Associated With Incidental Ovarian Cysts on Ultrasound
Rosenkrantz, Andrew B; Xue, X; Gyftopoulos, Soterios; Kim, Danny C; Nicola, Gregory N
PURPOSE/OBJECTIVE:To explore variation in downstream relative costs associated with ovarian cysts incidentally detected on ultrasound. METHODS:For 200 consecutive incidental ovarian cysts on ultrasound, ultrasound reports were classified in terms of presence of a radiologist recommendation for additional imaging. All downstream events (imaging, office visits, and surgery) associated with the cysts were identified from the electronic health record. Medical costs associated with these downstream events were estimated using national Medicare rates. Average cost per cyst was stratified by various factors; cost ratios were computed among subgroups. RESULTS:Average costs per cyst were 1.9 times greater in postmenopausal than premenopausal women. Relative to when follow-up imaging was neither recommended nor obtained, costs were 1.1 times greater when follow-up imaging was recommended but not obtained, 5.1 times greater when follow-up imaging was both recommended and obtained, and 8.1 times greater when follow-up imaging was obtained despite not being recommended. Costs were 2.5 times greater when the radiologist underrecommended follow-up compared with Society of Radiologists in Ultrasound (SRU) guidelines for management of ovarian cysts, 3.0 times greater when the ordering physician overmanaged compared with the radiologist's recommendation, as well as 1.7 times and 3.8 times greater when the ordering physician undermanaged and overmanaged compared with SRU guidelines, respectively. Four ovarian neoplasms, although no ovarian malignancy, were diagnosed in the cohort. CONCLUSION/CONCLUSIONS:Follow-up costs for incidental ovarian cysts are highly variable based on a range of factors. Radiologist recommendations may contribute to lower costs among patients receiving follow-up imaging. Such recommendations should reflect best practices and support the follow-up that will be of likely greatest value for patient care.
PMID: 29728324
ISSN: 1558-349x
CID: 3101312
Postoperative MRI of Massive Rotator Cuff Tears
Samim, Mohammad; Walsh, Pamela; Gyftopoulos, Soterios; Meislin, Robert; Beltran, Luis S
OBJECTIVE:The aim of this article is to review the postoperative MRI appearances of irreparable massive rotator cuff tears (RCTs) after surgery was performed using newer techniques, including patch repair, muscle tendon transfer, superior capsular reconstruction, and subacromial balloon implantation. CONCLUSION/CONCLUSIONS:Newer surgical techniques are emerging for the management of massive RCTs. As radiologists become increasingly likely to encounter postoperative imaging studies of RCTs repaired using these techniques, familiarity with the normal postoperative appearances and complications associated with these techniques becomes important.
PMID: 29792745
ISSN: 1546-3141
CID: 3150612
Comparison Between Image-Guided and Landmark-Based Glenohumeral Joint Injections for the Treatment of Adhesive Capsulitis: A Cost-Effectiveness Study
Gyftopoulos, Soterios; Abballe, Valentino; Virk, Mandeep S; Koo, James; Gold, Heather T; Subhas, Naveen
OBJECTIVE:The purpose of this study was to determine the cost-effectiveness of landmark-based and image-guided intraarticular steroid injections for the initial treatment of a population with adhesive capsulitis. MATERIALS AND METHODS/METHODS:A decision analytic model from the health care system perspective over a 6-month time frame for 50-year-old patients with clinical findings consistent with adhesive capsulitis was used to evaluate the incremental cost-effectiveness of three techniques for administering intraarticular steroid to the glenohumeral joint: landmark based (also called blind), ultrasound guided, and fluoroscopy guided. Input data on cost, probability, and utility estimates were obtained through a comprehensive literature search and from expert opinion. The primary effectiveness outcome was quality-adjusted life years (QALY). Costs were estimated in 2017 U.S. dollars. RESULTS:Ultrasound-guided injections were the dominant strategy for the base case, because it was the least expensive ($1280) and most effective (0.4096 QALY) strategy of the three options overall. The model was sensitive to the probabilities of getting the steroid into the joint by means of blind, ultrasound-guided, and fluoroscopy-guided techniques and to the costs of the ultrasound-guided and blind techniques. Two-way sensitivity analyses showed that ultrasound-guided injections were favored over blind and fluoroscopy-guided injections over a range of reasonable probabilities and costs. Probabilistic sensitivity analysis showed that ultrasound-guided injections were cost-effective in 44% of simulations, compared with 34% for blind injections and 22% for fluoroscopy-guided injections and over a wide range of willingness-to-pay thresholds. CONCLUSION/CONCLUSIONS:Ultrasound-guided injections are the most cost-effective option for the initial steroid-based treatment of patients with adhesive capsulitis. Blind and fluoroscopy-guided injections can also be cost-effective when performed by a clinician likely to accurately administer the medication into the correct location.
PMID: 29629805
ISSN: 1546-3141
CID: 3037172
Does the Addition of DWI to Fluid-Sensitive Conventional MRI of the Sacroiliac Joints Improve the Diagnosis of Sacroiliitis?
Beltran, Luis S; Samim, Mohammad; Gyftopoulos, Soterios; Bruno, Mary T; Petchprapa, Catherine N
OBJECTIVE:The purpose of this study was to determine whether adding DWI to conventional MRI of the sacroiliac joints improves the diagnostic performance of MRI readers in the detection of sacroiliitis. MATERIALS AND METHODS/METHODS:values of patients with and those without sacroiliitis were compared. RESULTS:AUC was 0.758 (95% CI, 0.67-0.83). CONCLUSION/CONCLUSIONS:The addition of DWI to conventional MRI does not significantly improve overall diagnostic performance in terms of accuracy, sensitivity, or confidence in the detection of inflammatory sacroiliitis, but it does have increased specificity and interobserver agreement. ADC threshold values can be used as predictors of sacroiliitis but give no added advantage over MRI with DWI.
PMID: 29629794
ISSN: 1546-3141
CID: 3037162
ACR Appropriateness Criteria® Chronic Wrist Pain
Rubin, David A; Roberts, Catherine C; Bencardino, Jenny T; Bell, Angela M; Cassidy, R Carter; Chang, Eric Y; Gyftopoulos, Soterios; Metter, Darlene F; Morrison, William B; Subhas, Naveen; Tambar, Siddharth; Towers, Jeffrey D; Yu, Joseph S; Kransdorf, Mark J
Radiographs are indicated as the first imaging test in all patients with chronic wrist pain, regardless of the suspected diagnosis. When radiographs are normal or equivocal, advanced imaging with MRI (without or without intravenous contrast or following arthrography), CT (usually without contrast), and ultrasound each has a role in establishing a diagnosis. Furthermore, these examinations may contribute to staging disease, treatment planning, and prognostication, even when radiographs are diagnostic of a specific condition. Which examination or examinations are best depends on the specific location of pain and the clinically suspected conditions. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 29724426
ISSN: 1558-349x
CID: 3061722
Who Refers Musculoskeletal Extremity Imaging Examinations to Radiologists?
Harkey, Paul; Duszak, Richard; Gyftopoulos, Soterios; Rosenkrantz, Andrew B
OBJECTIVE:The purpose of this study is to identify the specialty characteristics of providers referring musculoskeletal (MSK) extremity imaging examinations to radiologists, so as to better understand the drivers of MSK imaging utilization and potentially improve the appropriateness of such imaging examinations. MATERIALS AND METHODS/METHODS:Data on provider referral for MSK extremity imaging services were extracted from the 2014 Medicare Referring Provider Utilization for Procedures public use file, which aggregates data on diagnostic procedures according to referring provider identities and service codes. MSK extremity imaging services were identified using Neiman Institute Types of Service codes. The referring provider specialty was identified from cross-linked Medicare provider characteristics files. RESULTS:For 4,275,647 MSK extremity imaging examinations ordered, the most common specialties of the referring providers were orthopedic surgery (37.6% of ordered examinations), internal medicine (20.2%), family practice (14.8%), emergency medicine (7.9%), and rheumatology (5.7%). Orthopedic surgery was the referring specialty that most commonly ordered MSK extremity CT (33,465 ordered examinations; for all other specialties, < 2000 examinations), MRI (325,485 examinations; for all other specialities, < 20,000 examinations), and radiography (1,249,748 examinations; for all other specialities, < 850,000 examinations), whereas internal medicine was the referring specialty that most commonly ordered MSK extremity ultrasound examinations (8052 ordered examinations; for all other specialties, < 6000 examinations). Among the select specialties most relevant to MSK imaging, the most frequent referrers after orthopedic surgeons were rheumatologists, for radiography (236,057 ordered examinations) and ultrasound (2034 examinations), and podiatrists, for CT (1201 examinations) and MRI (19,159 examinations). The most commonly ordered individual MSK extremity imaging services were knee radiography, with 190,354 examinations ordered by orthopedic surgeons; hand radiography, with 66,167 examinations ordered by rheumatologists; foot radiography, with 137,042 examinations ordered by podiatrists; shoulder radiography, with 11,299 examinations ordered by sports medicine specialists; and hip radiography, with 9838 examinations ordered by physiatrists. CONCLUSION/CONCLUSIONS:Referral patterns for MSK imaging vary considerably by provider specialty. Referral pattern insights may guide targeted efforts by radiologists to ensure the appropriateness of such examinations.
PMID: 29489411
ISSN: 1546-3141
CID: 2965912