Faculty Bibliography

The purpose of this study was to compare short-term clinical outcomes between total hip arthroplasty (THA) and total knee arthroplasty (TKA) patient cohorts, adjusting for confounding variables including age, sex, body mass index, operative time, length of stay, and preoperative Western Ontario and McMaster Universities and 12-Item Short-Form Health Survey. A total of 349 patients who met inclusion and exclusion criteria created 2 cohorts: THA, 194, and TKA, 155, for statistical analysis via multiple regression and analysis of covariance measures. Outcome measures included Western Ontario and McMaster Universities and 12-Item Short-Form Health Survey data, collected prospectively at baseline and 2 years of follow-up. The current study showed that baseline characteristics of TKA patients have more factors with negative effect on postoperative outcome than THA. However, despite controlling for the possible confounding effect of these variables, THA patients experienced a significantly better functional outcome than TKA patients.

Total knee arthroplasty (TKA) can lead to substantial blood loss. To avoid the high costs of autologous blood predonation programs and efficiently allocate limited blood resources, we sought to identify preoperative and intraoperative factors associated with allogeneic blood transfusion (AllTx) after primary TKA and, subsequently, develop a model to predict patients who will require AllTx. We analyzed 31 independent variables in 644 primary unilateral TKAs without autologous blood predonation for requirement of AllTx. Seventy-one procedures (11.0%) required AllTx. Age, comorbid anemia, preoperative hemoglobin concentration, and surgical time were significant predictors for requiring AllTx. When applied to an independent cohort, our model for predicting the need for AllTx after TKA was 90% sensitive and 52.5% specific.

BACKGROUND: Intraarticular hip disease is commonly acknowledged as a cause of ipsilateral knee pain. However, this is based primarily on observational rather than high-quality evidence-based studies, and it is unclear whether ipsilateral knee pain improves when hip disease has been treated. QUESTIONS/PURPOSES: We asked whether (1) hip disease was associated with preoperative ipsilateral knee pain and (2) ipsilateral knee pain would improve after hip arthroplasty. PATIENTS AND METHODS: We retrospectively assessed knee pain in 255 patients who underwent hip arthroplasties between 2006 and 2008. The WOMAC pain score of each joint was the primary outcome measure, which was obtained prospectively before surgery and at 3 months and 1 year postoperatively. Of the 255 patients, 245 (96%) had followup data obtained at 3 months or 1 year. RESULTS: Preoperatively, ipsilateral knee pain was observed more frequently than contralateral knee pain (55% versus 18%). Preoperative ipsilateral knee pain scores were worse than contralateral knee pain scores (mean, 80 versus 95). Ipsilateral knee pain improved at 3 months and 1 year. When compared with the scores for contralateral knee pain at 3 months (95) and 1 year (96), there were no differences between knees. CONCLUSIONS: Our observations suggest hip disease is associated with ipsilateral knee pain and that it improves after hip arthroplasty. This should be considered during preoperative evaluation for patients with hip and knee pain. LEVEL OF EVIDENCE: Level III, diagnostic study. See Guidelines for Authors for a complete description of levels of evidence.

AIM: To identify factors that affect patient response rates to preoperative functional surveys in hip and knee arthroplasty patients. METHODS: From May 2008 to March 2009, 247 patients were scheduled more than 4 wk in advance for hip or knee arthroplasty by one of two participating surgeons at our center. A personalized questionnaire comprised of the Short Form 12 (SF-12) and Western Ontario and McMaster Universities (WOMAC) Index was mailed to patients at random time points ranging from 7 to 101 d prior to surgery. Nine independent factors were documented prospectively, including age, gender, ethnicity, marital status, type of surgery, surgeon, days prior to surgery (DPS) of survey mailing, WOMAC score and SF-12 score. The date of the completed survey receipt was also documented. For non-responders, the surveys were completed with the research team at the hospital upon admission. Multivariate regression and chi(2) analysis were performed with Statistical Analysis Software software. RESULTS: DPS was the only factor that affected patient response. Mailing surveys 26 d to 31 d prior to surgery dates led to a peak response rate of 80% that was significantly higher (P < 0.023) than response rates for patients who were mailed their surveys /= 32 d prior to surgery (55%). No other factors, including preoperative WOMAC and SF-12 scores, significantly influenced response behavior. CONCLUSION: The DPS was independently the most significant predictor of response rates for pre-operative functional data among patients scheduled for hip and knee arthroplasty.

Partial knee arthroplasty has enjoyed renewed interest during the past decade. It is helpful to be familiar with the classic and current indications, contraindications, and technical aspects of partial knee arthroplasty, including patellofemoral, medial unicompartmental, and lateral unicompartmental knee arthroplasty. Various implant choices for partial knee arthroplasty can be compared and evaluated based on patient characteristics, design qualities, and reported outcomes. It is also helpful to review the indications and techniques for performing medial or lateral unicompartmental knee arthroplasty in combination with arthroscopically assisted reconstruction of the anterior cruciate ligament.

BACKGROUND: The hemoglobin threshold at which postoperative red-cell transfusion is warranted is controversial. We conducted a randomized trial to determine whether a higher threshold for blood transfusion would improve recovery in patients who had undergone surgery for hip fracture. METHODS: We enrolled 2016 patients who were 50 years of age or older, who had either a history of or risk factors for cardiovascular disease, and whose hemoglobin level was below 10 g per deciliter after hip-fracture surgery. We randomly assigned patients to a liberal transfusion strategy (a hemoglobin threshold of 10 g per deciliter) or a restrictive transfusion strategy (symptoms of anemia or at physician discretion for a hemoglobin level of <8 g per deciliter). The primary outcome was death or an inability to walk across a room without human assistance on 60-day follow-up. RESULTS: A median of 2 units of red cells were transfused in the liberal-strategy group and none in the restrictive-strategy group. The rates of the primary outcome were 35.2% in the liberal-strategy group and 34.7% in the restrictive-strategy group (odds ratio in the liberal-strategy group, 1.01; 95% confidence interval [CI], 0.84 to 1.22), for an absolute risk difference of 0.5 percentage points (95% CI, -3.7 to 4.7). The rates of in-hospital acute coronary syndrome or death were 4.3% and 5.2%, respectively (absolute risk difference, -0.9%; 99% CI, -3.3 to 1.6), and rates of death on 60-day follow-up were 7.6% and 6.6%, respectively (absolute risk difference, 1.0%; 99% CI, -1.9 to 4.0). The rates of other complications were similar in the two groups. CONCLUSIONS: A liberal transfusion strategy, as compared with a restrictive strategy, did not reduce rates of death or inability to walk independently on 60-day follow-up or reduce in-hospital morbidity in elderly patients at high cardiovascular risk. (Funded by the National Heart, Lung, and Blood Institute; FOCUS ClinicalTrials.gov number, NCT00071032.).

Recently, implant companies have sought to target a more active segment of the population with high-flex implants. Our aim was to compare a successful medial UKA implant with its newer high-flex version. Sixty-one patients (nonflex, 33; high-flex [HF], 28) were prospectively followed after medial UKA with a minimum of 2-year follow-up. Patients were evaluated using Short Form 12, Western Ontario and McMaster Osteoarthritis (WOMAC), Knee Society Scores, and range of motion (ROM). The HF group exhibited significantly higher WOMAC Physical Function scores at 3-month follow-up and higher WOMAC Pain and SF-12 Mental Component scores at 2-year follow-up; all other comparisons were not statistically different, including ROM. The HF cohort had significantly higher improvements in Knee Society Function and Knee score at 1- and 2-year follow-up, respectively; all other comparisons yielded no significant differences in mean improvement from baseline, including ROM or survivorship.

This prospective cohort study compares functional outcomes of bicompartmental knee arthroplasty (BKA) and total knee arthroplasty (TKA) in patients with osteoarthritis (OA) of the patellofemoral and medial compartments. Eligibility criteria included bicompartmental OA with less than grade 2 OA in the lateral compartment and intact cruciate ligaments. Fifty-six patients met eligibility criteria (21 BKA, 33 TKA). Enrolled participants completed Short-Form 12 and Western Ontario and McMaster Universities Osteoarthritis Index assessments at baseline and postoperatively at 3 months, 1 year, and 2 years. In the early postoperative period, the BKA cohort had significantly less pain (P = .020) and better physical function (P = .015). These trends did not continue past 3 months. When adjusting for age, sex, body mass index, and preoperative status, only 3-month Western Ontario and McMaster Universities Osteoarthritis Index stiffness scores significantly differed between cohorts (P = .048). Despite less early stiffness in the BKA cohort, a significantly higher BKA complication rate (P = .045) has led us to recommend TKA for patients with this pattern of OA.

The purposes of this study were to evaluate the accuracy and reliability of preoperative templating on conventional radiographs (CRs) for metal-on-metal hip resurfacing and to determine the factors affecting the accuracy. Four observers templated 80 CRs on 2 separate occasions in a blinded fashion. Eight independent variables were evaluated to investigate their effect on the accuracy of templating. The overall accuracy of templating within one size of the actual component was 80.6% for the femoral component and 98.5% for the acetabular component. Overall, the intraobserver and interobserver reliability was fair to substantial (kappa = 0.22-0.61). Using multiple regression analysis, surgical time was the only factor that affected the accuracy of predicting the size of the acetabular component (P = .019). We conclude that CR templating for metal-on-metal hip resurfacing is a useful method for preoperative planning of the sizes of the respective implants and that surgeon experience does play a significant role in the accuracy of predicting component size during templating.

Total knee arthroplasty (TKA) is typically an extremely successful method of restoring pain-free function and providing good long-term outcomes for patients with end-stage knee disease. However, outcomes are less predictable in persons with Parkinson disease. The limited literature available and our experience lead us to conclude that complication rates in the perioperative and postoperative periods with TKA are comparatively high in persons with Parkinson disease. In addition, a good functional outcome is less certain than in the general population. For persons with Parkinson disease who require TKA, we propose an integrative, collaborative approach to avoid complications and optimize outcomes.