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An Observational Study of the Safety and Efficacy of Tissue Stabilized-Guided Subcision
Geronemus, Roy G; Kilmer, Suzanne L; Wall, Simeon H; Green, Jeremy B; Cohen, Joel L; Weiss, Robert A; Alster, Tina S; Kaminer, Michael S; Gupta, Anjali
BACKGROUND:Cellulite is a common female cosmetic concern for which there are few treatment options with long-term effectiveness data. The aim of this multisite prospective registry study was to collect observational data on the real-life clinical use of a tissue stabilized-guided subcision (TS-GS) system for long-term improvement of cellulite appearance. METHODS:Fifty-three subjects were enrolled and received a single treatment using the TS-GS system. Physicians treated the subjects according to their standard of care. Global Aesthetic Improvement Scale (GAIS) was completed by the patient and clinician assessing overall aesthetic improvement after 180 days. Treatment parameters, pain scores, quality of life data, and expected treatment effects and adverse events were also recorded throughout the study. RESULTS:The patient and physician GAIS scores at Day 180 revealed an overall improvement in 91% and 96% of patients, respectively. Quality of life and self-confidence scores also improved through 180 days. No serious adverse events were reported. Expected treatment effects were similar to those reported in the pivotal trial supporting FDA clearance. CONCLUSION/CONCLUSIONS:This study demonstrated significant improvement in the appearance of cellulite after a single treatment session in patients with moderate-to-severe cellulite. These results are consistent with the previously published the pivotal study data.
PMID: 30893161
ISSN: 1524-4725
CID: 3749082
Successful Utilization of Optical Coherence Tomography as a Non-Invasive, Bedside Imaging Technique To Identify Residual Nodular Basal Cell Carcinoma at Well-Healed and Clinically Unidentifiable Biopsy Site
Feng, Hao; Christman, Mitalee P; Holmes, Jon; Geronemus, Roy G
PMID: 30771419
ISSN: 1097-6787
CID: 3685542
Pulsed Dye Laser Treatment of Port-Wine Stains in Infancy Without the Need for General Anesthesia
Jeon, Hana; Bernstein, Leonard J; Belkin, Daniel A; Ghalili, Sabrina; Geronemus, Roy G
Importance/UNASSIGNED:Recent concerns regarding repetitive use of general anesthesia in children younger than 3 years have placed greater importance on the controversy surrounding the timing of the initiation of port-wine stain (PWS) laser treatment. Objective/UNASSIGNED:To evaluate the use of PWS treatments at the age of 1 year or younger in the office setting without general anesthesia. Design, Setting, and Participants/UNASSIGNED:Retrospective cohort study based on medical record reviews at a single, high-volume laser center for children who started pulsed dye laser treatment at the age of 1 year or younger for their PWS between 2000 and 2017. The data cutoff was at 1 year after the initial treatment to have comparable data points. Main Outcomes and Measures/UNASSIGNED:The primary outcome was improvement of PWSs using before and after photographs, which were reviewed by 4 physicians independently and graded using the following 5-point visual analog scale (VAS): poor (grade 1: 0%-25% improvement), fair (grade 2: 26%-50% improvement), good (grade 3: 51%-75% improvement), excellent (grade 4: 76%-99% improvement), and complete (grade 5: 100% improvement) clearance. Results/UNASSIGNED:Of the 197 patients (73 [37.1%] boys; 124 [62.9%] girls), most (149 [75.6%]) had facial lesions. The mean age at the time of first treatment was 3.38 months (range, 5-355 days) and the mean number of treatments was 9.8 (range, 2-23; median, 10). Per the mean physician VAS grading of 197 patients, 51 patients (25.9%) showed 100% clearance (mean [range] VAS score of 4.78 [4.5 - 5]); 81 patients (41.1%) showed 76 to 99% improvement (mean [range] VAS score of 3.91 [3.5 to <4.5]); 44 patients (22.3%) showed 51% to 75% improvement (mean [range] VAS score of 2.86 [2.5 to <3.5]); 13 patients (6.6%) showed 26% to 50% improvement (mean [range] VAS score of 2.12 [1.5 to <2.5]); and 8 patients (4.1%) showed 0 to 25% improvement (mean [range] VAS score of 0.78 [0 to <1.5]). The presence of a V1 (first branch of the trigeminal nerve [ophthalmic nerve]) lesion was associated with a statistically significantly higher clearance rate by a VAS grade of 0.55 (95% CI, 0.25-0.84; P < .001). The mean (SD) VAS grade for all patients was 3.65 (1.26), corresponding to excellent clearance. None of the patients experienced scarring or permanent pigmentary change. Conclusions and Relevance/UNASSIGNED:In this study, treatment of PWSs in infancy was both safe and effective. Early intervention allows for treatment without general anesthesia, maximizing the chance to achieve clearance before school age and thereby minimizing the negative outcome of PWSs for both the patient and the family.
PMID: 30865245
ISSN: 2168-6084
CID: 3733232
Safety of a Perfluorodecalin-Infused Silicone Patch in Picosecond Laser-Assisted Tattoo Removal: A Retrospective Review
Feng, Hao; Geronemus, Roy G; Brauer, Jeremy A
PMID: 29664770
ISSN: 1524-4725
CID: 3043042
Micrographic Surgery and Dermatologic Oncology Fellowship Selection Criteria
Feng, Hao; Belkin, Daniel A; Feng, Paula W; Geronemus, Roy G
BACKGROUND:Obtaining a fellowship position for Micrographic Surgery and Dermatologic Oncology (MSDO) is becoming very competitive. Applicant qualities desired by MSDO fellowship directors have not been previously explored in a systematic way. OBJECTIVE:To characterize the prevailing practices of selecting MSDO fellows. METHODS AND MATERIALS/METHODS:Cross-sectional study based on an anonymous online survey of MSDO fellowship directors. RESULTS:There were 34 completed surveys. Selection criteria with the highest importance to fellowship directors were the ability to work well and get along with others, interview, work ethic, and letter of recommendation from the Mohs micrographic surgery director at the applicant's residency. The criteria with the lowest importance were advanced degrees, medical licensing examination scores, and membership in Alpha Omega Alpha. Specific applicant factors that were looked upon most positively by fellowship directors include applicant from own institution and applicant's personal reasons and circumstances, whereas factors that were most unfavorable include applicant's desire to practice in the same city/area as the fellowship location and graduate of foreign medical school. CONCLUSION/CONCLUSIONS:Although variations existed, MSDO fellowship directors collectively placed greater importance on criteria that reflect interpersonal skills than on objective measures of academic performance, which highlights the importance of "fit."
PMID: 30199433
ISSN: 1524-4725
CID: 3275622
Geographic Distribution of U.S. Mohs Micrographic Surgery Workforce
Feng, Hao; Belkin, Daniel; Geronemus, Roy G
PMID: 29620564
ISSN: 1524-4725
CID: 3026112
Characteristics of opioid prescriptions by Mohs surgeons in the Medicare population [Meeting Abstract]
Kakpovbia, Efe; Feng, Hao; Petriceks, Aldis; Feng, Paula W.; Geronemus, Roy G.
ISI:000482195001301
ISSN: 0190-9622
CID: 4086112
Successful treatment of a traumatic tattoo in a pediatric patient using a 755-nm picosecond laser
Jeon, Hana; Geronemus, Roy G
We report a case of successful treatment of a traumatic tattoo in a 2-year-old patient. He presented with a green discoloration on the left infraorbital region after his sister accidentally hit him with a face paint brush while playing together. A single treatment with an alexandrite picosecond laser resulted in a complete clearance without any side effects for this disfiguring condition.
PMID: 30303558
ISSN: 1525-1470
CID: 3334982
Retrospective Multistudy Analysis of Axillary Odor Reduction After Microwave Treatment
Yagerman, Sarah; Brauer, Jeremy A; Geronemus, Roy G
PMID: 29360656
ISSN: 1524-4725
CID: 2929322
Three-Dimensional Analysis of Minimally Invasive Vacuum-Assisted Subcision Treatment of Cellulite
Brauer, Jeremy A.; Christman, Mitalee P.; Bae, Yoon Soo C.; Bernstein, Leonard J.; Anolik, Robert; Shelton, Ron; Geronemus, Roy G.
Introduction:This was a prospective non-randomized observational study of female subjects seeking treatment for cellulite who were consecutively enrolled into a registry. The objective was to evaluate the efficacy and safety of a tissue stabilized-guided subcision device for the treatment of cellulite using three-dimensional (3D) imaging analysis. ISI:000453940900005
ISSN: 1545-9616
CID: 3560712