Faculty Bibliography

BACKGROUND:Routine immediate postoperative laboratory studies, including metabolic panels and hematologic profiles, are commonly ordered after arthroplasty procedures. However, their values only occasionally influence management. This study investigated the clinical utility and value of these tests. METHODS:A large retrospective cohort study of 18,935 patients spanning a 6-year period from 2008 to 2013 from a single high-volume institution was evaluated. Only immediate postoperative labs drawn on postoperative day 0 in the recovery room were included in the study. Complete blood counts (CBC) and basic metabolic panels (BMP) were reviewed, and ranges of abnormal were set for each lab test based on values significant enough to impact patient management. Cost effectiveness calculations were made based on current cost of the laboratory tests. RESULTS:Actionably low hemoglobin values ( < 8 g/dL) were found in 1.44% of the overall cohort. Unilateral primary total knee arthroplasty was associated with the fewest hemoglobin abnormalities at 0.59%. Primary unilateral total hip arthroplasty was associated with abnormal hemoglobin values in 1.81% of cases. Significant electrolyte abnormalities were far less common, with hyperkalemia (> 6.5 mEq/L) in 0.19%, hyponatremia ( < 120 mEq/L) in 0.01% and elevated creatinine (> 2.0 mg/dL) was found in 0.25%. Hemoglobin values were calculated at a cost of $1,710 to detect a single significantly abnormal result. The cost to detect a single actionably abnormal BMP value was $1,000. CONCLUSIONS:Routine immediate postoperative laboratory tests represent a high institutional cost and are seldom abnormal enough to warrant a change in patient management. The routine use of these tests can likely be safely eliminated in uncomplicated primary unilateral arthroplasty procedures.

Disparities in musculoskeletal health care exist across race, ethnicity, sex, and socioeconomic status. Because medical and socioeconomic comorbidities disproportionately affect certain patient populations, the transition to a value-based model of healthcare delivery and reimbursement based on current methodology has unintentionally intensified musculoskeletal healthcare disparities. To address healthcare disparities, surgeons must understand the history and effect of a value-based model of healthcare delivery and reimbursement and the current risk adjustment and reporting initiatives that inform future directions of healthcare systems. Attention to bias and the use of shared decision making at the patient-surgeon level may help promote more equitable care. At the health systems level, surgeons can collect demographic data via registries and use existing disparity-related reporting measures to promote more equitable care. The development of quality reporting measures and risk stratification models that encourage the delivery of equitable musculoskeletal health care for all patients is necessary.

BACKGROUND: Revision total hip arthroplasty (RHA) has been associated with greater morbidity and length of stay (LOS) compared to primary total hip arthroplasty. Despite this, few validated metrics exist for risk stratification in RHA cohorts. The Charlson Comorbidity Index (CCI) has been associated with complications in total hip arthroplasty, but its utility in revision surgery remains unexplored. The purpose of this study was to examine the relationship between preoperative CCI and a variety of outcome metrics following RHA. METHODS: The National Surgical Quality Improvement Program database was used to identify all patients undergoing aseptic RHA between 2006 and 2013. A variety of demographics and perioperative variables were collected. Modified CCI scores were computed for each patient based on a validated formula incorporating comorbidities found in the National Surgical Quality Improvement Program database. Outcome variables of interest included mortality, major postoperative complications, minor adverse events, incidence of transfusion, and prolonged LOS. Perioperative factors were tested for association with these outcomes using bivariate analysis and significant variables were then incorporated into a logistic regression model to explore the relationship between preoperative CCI scores and postoperative events. RESULTS: In a multivariable regression model controlling for the significant perioperative variables, operative time, and American Society of Anesthesiologists classification, higher CCI scores were significantly associated with mortality (odds ratio [OR] 1.89, 95% confidence interval [CI] 1.64-2.18, P < .001), major complications (OR 1.12, 95% CI 1.05-1.20, P = .001), minor complications (OR 1.53, 95% CI 1.39-1.69, P < .001), transfusions (OR 1.14, 95% CI 1.09-1.20, P < .001), and prolonged LOS (OR 1.32, 95% CI 1.26-1.39, P < .001). CONCLUSION: Higher preoperative CCI scores were independent risk factors for numerous complications. This highlights the potential utility of the CCI in risk stratification for RHA populations.

BACKGROUND: Educational and computerized interventions have been shown to reduce red blood cell (RBC) transfusion rates, yet controversy remains surrounding the optimal strategy needed to achieve sustained reductions in liberal transfusions. STUDY DESIGN AND METHODS: The purpose of this study was to assess the impact of clinician decision support (CDS) along with targeted education on liberal RBC utilization to four high-utilizing service lines compared with no education to control service lines across an academic medical center. Clinical data along with associated hemoglobin levels at the time of all transfusion orders between April 2014 and December 2015 were obtained via retrospective chart review. The primary outcome was the change in the rate of liberal RBC transfusion orders (defined as any RBC transfusion when the hemoglobin level is >7.0 g/dL). Secondary outcomes included the annual projected reduction in the number of transfusions and the associated decrease in cost due to these changes as well as length of stay (LOS) and death index. These measures were compared between the 12 months prior to the initiative and the 9-month postintervention period. RESULTS: Liberal RBC utilization decreased from 13.4 to 10.0 units per 100 patient discharges (p = 0.002) across the institution, resulting in a projected 12-month savings of $720,360. The mean LOS and the death index did not differ significantly in the postintervention period. CONCLUSION: Targeted education combined with the incorporation of CDS at the time of order entry resulted in significant reductions in the incidence of liberal RBC utilization without adversely impacting inpatient care, whereas control service lines exposed only to CDS had no change in transfusion habits.

Paget's disease of the bone is a chronic osteopathy that leads to structural weakness, hypervascularity, and bone deformities. Rapid bone turnover in patients with Paget's disease may affect outcomes following total hip arthroplasty (THA). Most literature on THA in the setting of Paget's disease is limited to isolated case reports or case series documenting a single institution experience. By completing a comprehensive analysis of the available cases, this study aims to investigate the outcomes and complications of THA in patients with Paget's disease.

A 35-year-old female presented to orthopaedic clinic with a chief complaint of chronic left hip pain, beginning 17 years prior when she had sustained a gunshot wound to her left buttock. Imaging demonstrated significant left hip arthritis with a retained projectile in the femoral head. Lead levels were also found to be significantly elevated. The patient underwent successful left total hip arthroplasty, with subsequent postoperative pain relief and consistent decrease in serum lead level. This report presents a rare case that emphasizes lead intoxication as a potentially dangerous complication of gunshot wounds and retained projectiles in the orthopaedic patient. Recognition of lead intoxication as a potential complication of retained gunshot projectiles allows for efficient diagnosis and treatment, which may prevent associated future morbidity.