Faculty Bibliography

PURPOSE/OBJECTIVE:To evaluate whether incorporation of arterial injury into CT-based zone-of-injury (ZOI) models improves complication prediction after open tibial shaft fractures. METHODS:A retrospective cohort study was conducted at an urban multicenter academic hospital (2012-2024). Patients ≥ 18 years with open OTA 42A-C tibia fractures, preoperative CT, and ≥ 6 months follow-up were included. Arterial injury and wound location within the anterior tibial, posterior tibial, or peroneal angiosomes were identified on CT angiography. Soft-tissue ZOI (longitudinal extent of soft-tissue air) and fracture ZOI (fracture span) were normalized to tibial length. The primary outcome was a composite complication of fracture-related infection, nonunion, or amputation. Logistic regression identified predictors, and ROC analysis compared discrimination of (1) an angiosome-augmented ZOI model, (2) a standard ZOI model, and (3) Gustilo-Anderson classification. RESULTS:Eighty-two patients were included: 32 (39.0%) developed major complications. Arterial injury was present in 11 patients and significantly associated with complications (72.7% vs 33.8%, p = 0.020). The augmented ZOI model included arterial injury, anterior angiosome involvement, number of angiosomes affected, normalized soft-tissue ZOI, and BMI (AUROC 0.777), outperforming the standard ZOI model (AUROC 0.707) and Gustilo-Anderson classification (AUROC 0.592). DeLong testing showed no significant difference between ZOI and the augmented model. CONCLUSION/CONCLUSIONS:The original CT-based ZOI model, which incorporates soft-tissue injury measurements normalized to tibial length and BMI, remains a robust objective predictor of complications following open tibial shaft fractures, consistent with prior published work. While arterial injury is associated with adverse outcomes, its addition to ZOI-based models does not significantly improve predictive performance. Notably, only the arterial-augmented ZOI model demonstrated a statistically significant improvement in discrimination over the Gustilo-Anderson classification, whereas the standard ZOI model did not reach significance in this cohort, suggesting that augmentation may be necessary to meaningfully surpass subjective wound grading. LEVEL OF EVIDENCE/METHODS:III.

PURPOSE/OBJECTIVE:To evaluate the effect of baseline dementia on postoperative outcomes in hip fracture patients undergoing hemiarthroplasty. METHODS:A retrospective review was conducted of patients aged 55 years or older who underwent hemiarthroplasty for displaced femoral neck fracture (AO/OTA 31B) between 2012 and 2024 at a large urban academic institution. Dementia was identified by ICD-10 codes and confirmed by chart review. A 3:1 propensity score matched cohort was created using the Score for Trauma Triage in Geriatric and Middle-aged (STTGMA). Demographics and baseline characteristics were compared to ensure similarity. Outcomes included total complications, major and minor complications, periprosthetic dislocation, length of stay, ICU admission, discharge location, 30- and 90-day readmission, revision surgery, inpatient, and 30-day and 1-year mortality. RESULTS:A total of 1,030 patients were included, with 241 patients with dementia and 839 controls. After 3:1 STTGMA propensity matching, baseline characteristics were comparable (mean age 82.75 vs. 83.0 years, P = 0.065; Charlson Comorbidity Index 1.96 vs. 1.92, P = 0.42; STTGMA 0.022 vs. 0.020, P = 0.50). Patients with dementia had increased major complications (17.92% vs. 10.93%, P = 0.013), including sepsis (5.00% vs. 2.21%, P = 0.027), urinary tract infections (13.33% vs. 6.78%, P = 0.002), and hip hemiarthroplasty dislocations (6.25% vs. 2.21%, P = 0.002). Patients with dementia also had longer length of stay (7.84 ± 5.83 vs. 6.80 ± 2.24 days, P = 0.030), increased 30-day readmissions (15.83% vs. 8.85%, P < 0.001), increased 90-day readmission (20.00% vs. 11.76%, P < 0.001), and higher 1-year mortality (16.25% vs. 8.02%, P < 0.001). No differences were observed in pneumonia, stroke, myocardial infarction, cardiac arrest, venothromboembolism, acute kidney injury, anemia, and revision surgery. CONCLUSION/CONCLUSIONS:Dementia was associated with increased major complications, hip hemiarthroplasty dislocations, higher readmission, and mortality after hemiarthroplasty. These findings highlight the need for targeted perioperative planning and multidisciplinary care pathways in cognitively impaired patients.

IntroductionTourniquet use for ankle fracture fixation surgery is a common but not universally accepted practice due to concerns regarding soft tissue complications. Although prior literature has demonstrated increased short-term postoperative pain, tourniquet use's association with other complications remains under-investigated.MethodsA retrospective cohort study was performed of adult patients undergoing open reduction and internal fixation of a closed rotational ankle fracture (OTA Type 44) between 2012 and 2024 at an urban academic health system. Patients were stratified by tourniquet use. Demographic information, injury characteristics, and operative variables were collected. The primary outcome was the development of postoperative complications-wound dehiscence, fracture-related infection, superficial wound infection, delayed wound healing, peripheral nerve injury, venous thromboembolism, and nonunion. Secondary outcomes were operative time and estimated blood loss. Multivariable logistic regression was used to evaluate the association between tourniquet use and postoperative complications.ResultsA total of 617 patients met the inclusion criteria, including 446 who had a tourniquet inflated during surgery and 171 who did not. No significant differences in baseline patient demographics or comorbidity were observed. After multivariable logistic regression, tourniquet use was not associated with higher odds of any wound complication, fracture-related infection, delayed wound healing, or peripheral nerve injury. Among patients in the tourniquet cohort, 4 developed venous thromboembolism and 7 developed a fracture nonunion. No such complications were observed among patients treated without a tourniquet. Tourniquet use was associated with a modest decrease in estimated blood loss (47.3 ± 44.2 vs 33.9 ± 36.0 mL, P < .001) with no significant increase in operative time.ConclusionTourniquet use during operative fixation of closed rotational ankle fractures was not associated with increased soft tissue or bony complications. The findings support the safety of continued tourniquet use per surgeon preference, provided that appropriate patient selection is employed.

INTRODUCTION/BACKGROUND:The purpose of this study was to determine whether CT Hounsfield units (HUs) as a proxy for bone quality can predict postoperative mechanical complications following surgical treatment of distal humerus fractures. METHODS:One hundred fifty-three patients with both column distal humerus fractures who underwent surgical fixation at single institution and had complete radiographic data available were included. Radiographic measurements included the HU value from the surgical distal humerus as determined by measuring the metaphyseal/supracondylar at the midaxial/coronal/sagittal CT image an average of 1 cm from the articular surface using a freehand region of interest. Zones with fracture lines and cortical impaction were avoided for all measurements. Postoperative complications recorded were implant failure, nonunion, and acute periprosthetic fracture. Patients with and without complications were statistically compared, and binary logistic regression was done to determine if CT HU measurements from the distal humerus were predictive of complications. RESULTS:Five patients (3.3%) developed five mechanical complications, including peri-prosthetic humerus fracture (one), implant failure (two), and nonunion (two). Patients with mechanical complications were more likely to be current smokers (40% vs. 6.8%, P = 0.010). Otherwise, no difference was observed in demographics or AO/Orthopedic Trauma Association classification between the cohorts. Patients with complications had markedly lower HU in the coronal plane (P = 0.031). Regression analysis found that current smoking was associated with an increased risk of mechanical complications (P = 0.041, OR = 1.102, 95% confidence interval [CI], 1.087 to 1.710), whereas a higher coronal HU was associated with a decreased risk of complications (P = 0.048, OR = 0.973, 95% CI, 0.961 to 0.991). CONCLUSION/CONCLUSIONS:A thorough smoking history and CT HU measurements in the coronal plane may identify patients with poorer bone quality at higher risk for postoperative mechanical complications following distal humerus fracture fixation.

BACKGROUND/UNASSIGNED:To compare functional outcomes between obese and non-obese patients after intramedullary nail (IMN) fixation of OTA 42A-C tibial fractures. Secondarily, to compare clinical outcomes and union rates between cohorts. METHODS/UNASSIGNED:). Univariate comparisons between cohorts were performed, and multivariable regression was used to adjust for confounders. RESULTS/UNASSIGNED:286 patients met inclusion criteria: 60 (21.0%) were obese and 226 (79.0%) were non-obese. The mean follow-up time was 13.60 ± 7.90 months. There were no differences in injury or demographic characteristics, besides a higher rate of diabetes in the obese group (20% vs. 5.3%, p < 0.001). Obesity was associated with lower 3-month (B = -0.352, p = 0.009), 6-month (B = -0.283 p = 0.013) and 12-month (B = -0.181 p = 0.039) FAC scores when controlling for baseline FAC score, age, fracture pattern, diabetes, and open fractures. The obese group was not associated with fracture nonunion (81.7% vs. 90.3%, p = 0.064) and showed no difference in healed-by times (6.28 ± 2.45 [months] vs. 6.13 ± 2.83, p = 0.751). The obese group had a higher rate of amputation (5% vs. 0%, p < 0.001) but no difference in overall complication rate (28.3% vs. 18.0%, p = 0.081). CONCLUSIONS/UNASSIGNED:Obese patients who undergo intramedullary nail fixation of OTA 42A-C tibial diaphyseal fractures have worse functional ambulatory outcomes compared to their non-obese counterparts.

The gold standard for patella fracture fixation is tension band wiring; however, achieving stable anatomic fixation can be challenging in comminuted patterns. The "star" variable-angle locking patella plate is an alternative fixation construct that is meant to address these limitations by providing multiple fixation points and dorsal cortical stability. The purpose of this study was to analyze the outcomes of patients treated with the variable-angle locking "star" patella plate. A total of 358 patients who underwent repair of a displaced patella fracture over a 10-year period were reviewed. Patients who sustained an isolated orthopaedic trauma association (OTA) 34-C3 patella fracture and underwent open reduction internal fixation (ORIF) with the variable-angle locking star-shaped patella plating system with at least 6 months of follow-up were analyzed. Demographic and treatment characteristics, fracture union, complications, and functional outcome measures as measured by knee range of motion (ROM) were collected retrospectively at standard follow-up intervals. Thirty-seven patients (mean age 60.17 ± 16.72 [standard deviation, SD] years; mean body mass index [BMI] 25.12 ± 5.04 [SD] kg/m²) treated at one multisite, urban, academic institution were identified. All fractures were classified as OTA 34-C3. The mean operating room time (wheels-in wheels-out) was 149.43 ± 50.82 (SD) minutes. One patient (2.7%) developed a fracture-related infection (FRI), two patients (5.4%) had wound complications, and one patient (2.7%) developed a deep vein thrombosis (DVT) following surgery. All fractures healed by 6 months, and no patient underwent removal of symptomatic hardware. Three patients underwent secondary operation; one patient had repeated irrigation and debridement of a confirmed FRI, one manipulation under anesthesia for knee contracture, and one revision ORIF after loss of distal fixation. Patients displayed a mean knee ROM of 106.53 ± 21.64 degrees (SD) and 118.51 ± 16.87 degrees (SD) at the 3- and 6-month points, respectively. The novel locking "star" patella plate appears to be a reliable and safe method of treatment for the most complex patella fractures.

Orthopedic surgery has advanced through the demands of managing complex musculoskeletal trauma on the battlefield. The purpose of this review was to briefly summarize how successive conflicts have shaped principles and practice of orthopedic surgery-from wound management, fracture stabilization, limb salvage, prosthetics, and trauma systems-and to outline possible orthopedic input in future warfare and human exploration. From early empiricism in the Revolutionary War to organized military hospital systems in the Civil War, to the use of antibiotics and internal fixation in World War II, each armed conflict has introduced core orthopedic tenets and innovations. World War I introduced improvements in wound care and early femoral fracture stabilization (Thomas splint), dramatically reducing mortality. World War II brought on the innovation of Küntscher intramedullary nailing and the birth of hand surgery. The Korean and Vietnam wars accelerated evacuation and echeloned care, laying groundwork for damage control orthopedics. In Iraq and Afghanistan, tiered trauma systems and prospective outcomes data reframed limb salvage vs. amputation; contemporary prosthetics (targeted muscle reinnervation, myoelectric control, osseointegration) further expanded function. Future domains-remote warfare and space medicine-pose distinct challenges and research imperatives. Orthopedic surgery's evolution is inseparable from the history of war. Lessons in physiology-first care, principles of bony fixation, wound care, infection control, and multidisciplinary rehabilitation continue to inform modern civilian practice and will be essential for managing complexing injuries in emerging environments.

The purpose of this study was to compare outcomes in patients who sustained isolated lateral column tibial plateau fractures and combined lateral and posterolateral column tibial plateau fractures (AO/OTA 41B3 lateral split-depression fractures). Fractures were classified according to the three-column classification system of tibial plateau fractures. The primary outcome was the difference in Short Musculoskeletal Function Assessment (SMFA) function index at 12 months postoperatively between patients with lateral column plateau fractures and patients with combined lateral and posterolateral column plateau fractures. Seventy-eight patients were included (mean age: 48.8 ± 14.1 years). Thirty-two patients (41.0%) were in the isolated lateral column group (L), and 46 patients (59.0%) were in the lateral column plus posterolateral column group (L + PL). At 1 year following injury and fixation, the L + PL group demonstrated significantly worse SMFA function index than the L group (19.1 ± 17.7 vs. 9.1 ± 12.5, p = 0.005). Similarly, the L + PL group was significantly more bothered by the sequelae of their injury compared to the L group at 1 year based on the SMFA bothersome index (20.7 ± 23.7 vs. 8.6 ± 12.3, p = 0.005). Patients with combined lateral and posterolateral column tibial plateau fractures demonstrate worse outcomes compared to isolated lateral column fractures 1 year after fixation. The study provides level III evidence.

PURPOSE/UNASSIGNED:To report the technique and describe the outcomes of the use of a medial support fibular strut construct for treating varus humeral surgical neck nonunions in older patients. METHODS/UNASSIGNED:Older patients (≥ 60 years) who presented with a surgical neck varus nonunion initially treated with or without previous surgery were identified. All patients underwent repair with nonunion takedown, anatomic alignment with a plate and screw construct, and medial cortical substitution with an allograft fibular strut and autogenous iliac crest graft. Patients were followed prospectively. Patient demographics, injury and surgery characteristics, radiographic and clinical healing, in-hospital and post-operative complications, and follow-up range of motion were systematically collected and analyzed. RESULTS/UNASSIGNED:Six patients, mean age 70.5 ± 8.7, who presented with an atrophic humeral surgical neck nonunion with medial calcar deficiency were identified. All six patients (100%) achieved union with an average healing time of 4.5 months. One patient required an early revision due to hardware failure 3 weeks following revision surgery. At the 12-month follow-up, forward elevation of the shoulder averaged 138° ± 33°. Significant functional improvement was observed, with average preoperative SMFA scores of 42.0 ± 11.1 improving to 11.1 ± 12.1 12 months post-operatively. CONCLUSION/UNASSIGNED:The use of a fibular strut construct as a solution for humeral surgical neck nonunion with medial calcar loss demonstrates an alternative treatment for a complex type of proximal humerus nonunion in older populations. Patients who healed experienced high rates of functional recovery, underscoring its effectiveness as a treatment modality.