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246


Real-world diagnostic performance of knee MRI protocols accelerated using simultaneous multi-slice acquisition and deep learning reconstruction

Johnson, Patricia M; Dogra, Siddhant; Westerhoff, Malte; Fritz, Jan; Lin, Dana J; Recht, Michael P
OBJECTIVE:To assess whether accelerated knee MRI protocols using simultaneous multi-slice (SMS) and deep learning reconstruction (DLR) are non-inferior to a conventional parallel imaging protocol for detecting internal derangement injuries. METHODS:This retrospective cohort study included 1055 patients who underwent knee MRI followed by arthroscopy within 180 days. Patients were scanned using either a conventional protocol (n = 226), an accelerated SMS protocol (n = 406), or a SMS with DLR protocol (n = 423). Each group included consecutive exams. Imaging was performed on 3 T MRI using five standardized two-dimensional turbo spin echo sequences. Radiology interpretations were compared with arthroscopy (reference standard) for anterior cruciate ligament (ACL), medial meniscus (MM), and lateral meniscus (LM) tears. Sensitivity and specificity were calculated with 95% confidence intervals using non-parametric bootstrapping. Non-inferiority was concluded if the upper bound of the 95% confidence interval for the difference in sensitivity and specificity was ≤ 0.05. RESULTS:Among all patients, 666 had MM tears, 417 had LM tears, and 220 had ACL tears. Sensitivity for ACL tears was higher with accelerated protocols (0.96 and 0.98) than the conventional (0.85), with non-inferiority confirmed. Specificity was ≥ 0.98 across all protocols. MM sensitivity (0.94-0.95) met non-inferiority criteria. MM specificity (0.88-0.91) and LM sensitivity (0.63-0.68) were not statistically different across protocols but did not meet the non-inferiority margin. LM specificity (0.94) met non-inferiority criteria. CONCLUSION/CONCLUSIONS:Accelerated MRI protocols using SMS and DLR demonstrated comparable diagnostic performance to the reference protocol. Although not all metrics met the strict non-inferiority margin, none showed statistically significant reductions in sensitivity or specificity. These findings support the clinical adoption of accelerated protocols for faster, high-throughput knee imaging.
PMID: 41109866
ISSN: 1432-2161
CID: 5955482

[Macrodystrophia lipomatosa with fibrolipomatous hamartoma of the median nerve, sciatic nerve and brachial plexus]

Horger, Marius; Fritz, Jan; Gohla, Georg; Heckl, Stefan
PMID: 40972641
ISSN: 1438-9010
CID: 5935642

MR Neurography of the Foot and Ankle Nerves

Leonhardt, Yannik; Fritz, Jan
MR neurography offers a specialized approach for detailed nerve imaging when clinical symptoms indicate involvement. Imaging peripheral nerves in the foot and ankle is demanding due to their small size and challenging anatomy. This article provides an overview of foot and ankle nerve assessment, highlighting the importance of technical expertise and anatomic knowledge for accurate diagnosis.
PMID: 40610164
ISSN: 1557-9786
CID: 5888392

mapping near metallic implants using turbo spin echo pulse sequences

Khodarahmi, Iman; Bruno, Mary; Schwarzkopf, Ran; Fritz, Jan; Keerthivasan, Mahesh B
PURPOSE/OBJECTIVE:mapping technique for imaging of body parts containing metal hardware, based on magnitude images acquired with turbo spin echo (TSE) pulse sequences. THEORY AND METHODS/METHODS:values were validated against gradient-recalled and spin echo dual angle methods, as well as a vendor-provided TurboFLASH-based mapping sequence, in gel phantoms and human subjects without and with metal implants. RESULTS:shimming. CONCLUSION/CONCLUSIONS:values in regions near metal hardware, overcoming susceptibility-related and narrow-range limitations of standard mapping techniques.
PMID: 40079274
ISSN: 1522-2594
CID: 5808662

MRI grading using the neuropathy score-reporting and data system with electrodiagnostic correlation in radial neuropathy around the elbow: a 13-year retrospective review

Abiri, Benjamin; Kopylov, David; Samim, Mohammad; Walter, William; Fritz, Jan; Khodarahmi, Iman; Burke, Christopher J
OBJECTIVE:To evaluate the Neuropathy Score-Reporting and Data System (NS-RADS) MRI grading system in conjunction with electrodiagnostic (EDx) testing for radial neuropathy at the elbow. MATERIALS AND METHODS/METHODS:Patients presenting between 2010 and 2023 with suspected radial neuropathy who underwent both EDx testing in the form of electromyography and nerve conduction studies and MRI within a 12-month period were evaluated. Three blinded radiologists used the NS-RADS grading system to evaluate nerve entrapment (E grades), muscle denervation (M grades) proximally within the supinator/extensor carpi radialis brevis (ECRB), and more distally within the forearm extensor muscles. These grades and the presence of lateral epicondylitis were then correlated with EDx abnormalities. RESULTS:Forty-nine participants were included. Inter-reader reliability for M grades in the forearm extensor muscles was good (ICC = 0.90 [95% CI = 0.83 - 0.94], p < 0.001), as was reliability for the supinator/ECRB muscles (ICC = 0.91 [95% CI = 0.86-0.95], p < 0.001). Inter-reader reliability for E grades was moderate (ICC = 0.83 [95% CI = 0.69-0.90], p < 0.001). Patients with positive EDx studies had a significantly different distribution of M grades for the forearm extensors and supinator/ECRB than those with negative studies (all p values < 0.001). However, overall consensus reads showed no significant difference in the distribution of E grades between patients with positive and negative EDx studies. CONCLUSION/CONCLUSIONS:Muscle grading strongly correlated with EDx positivity, with a high level of inter-reader agreement for muscle denervation-related alterations. Nerve grading, however, did not show a statistical correlation.
PMID: 39760931
ISSN: 1432-2161
CID: 5804892

[Intraneural ganglion cysts at the superior tibiofibular joint]

Heckl, Stefan; Gohla, Georg; Fritz, Jan; Ruff, Christer; Horger, Marius
PMID: 40669504
ISSN: 1438-9010
CID: 5897242

[Mucoid degeneration of the anterior and posterior cruciate ligament: MR-Imaging findings and differential diagnoses]

Horger, Marius; Fritz, Jan; Gohla, Georg; Ruff, Christer; Heckl, Stefan
PMID: 40669505
ISSN: 1438-9010
CID: 5897252

Clinical Implementation of Sixfold-Accelerated Deep Learning Super-Resolution Knee MRI in Under 5 Minutes: Arthroscopy-Validated Diagnostic Performance

Vosshenrich, Jan; Breit, Hanns-Christian; Donners, Ricardo; Obmann, Markus M; Walter, Sven S; Serfaty, Aline; Rodrigues, Tatiane Cantarelli; Recht, Michael; Stern, Steven E; Fritz, Jan
PMID: 40266704
ISSN: 1546-3141
CID: 5830272

[Adhesive capsulitis (frozen shoulder): MR-characteristics]

Heckl, Stefan; Fritz, Jan; Gohla, Georg; Horger, Marius
PMID: 40623434
ISSN: 1438-9010
CID: 5890512

[MR-imaging of intersection syndromes of the forearm and wrist]

Horger, Marius; Gohla, Georg; Fritz, Jan; Heckl, Stefan
PMID: 40209750
ISSN: 1438-9010
CID: 5824182