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Interdisciplinary consensus statements on imaging of scaphoid fractures

Dietrich, Tobias Johannes; Teh, James; Schmitt, Rainer; Blum, Alain; Hesse, Nina; Lalam, Radhesh Krishna; Toms, Andoni Paul; Becce, Fabio; Omoumi, Patrick; Shahabpour, Maryam; Bień, Maciej; Zanetti, Marco; Boutin, Robert Downey; Fritz, Jan; Llopis, Eva; Bazzocchi, Alberto; Afonso, P Diana; Mascarenhas, Vasco V; Sutter, Reto; Cotten, Anne; Drapé, Jean-Luc; Bierry, Guillaume; Pracoń, Grzegorz; de Jonge, Milko C; Dalili, Danoob; Mespreuve, Marc; Klich, Maciej; Nagy, Ladislav; Szabo, Robert M; Grünert, Jörg G; Camus, Emmanuel J; Bain, Gregory Ian; Mathoulin, Christophe L; Goehtz, Florian; Garcia-Elias, Marc; Van Overstraeten, Luc; Del Piñal, Francisco; Atzei, Andrea; Luchetti, Riccardo; Chojnowski, Adrian Julian; Czarnecki, Piotr; Corella, Fernando; Yamamoto, Michiro; Golubev, Igor O; van Schoonhoven, Jörg; Cerezal, Luis; Sudoł-Szopińska, Iwona
OBJECTIVES/OBJECTIVE:To establish evidence-based consensus statements on imaging of scaphoid fractures. MATERIALS AND METHODS/METHODS:Nineteen hand surgeons formulated a preliminary list of eleven questions on imaging of scaphoid fractures. Based on this preliminary list, radiologists crafted statements considering literature and their clinical experience, then refined them through an iterative Delphi process to revise the questions and statements. A maximum of three Delphi rounds was scheduled until group consensus was achieved for an individual statement, whichever arose first. Twenty-eight radiologists drafted the statements and acted as Delphi panellists. Panellists rated their level of agreement with each statement on an 11-point numeric rating scale, the score '0' indicated complete disagreement and the score '10' indicated complete agreement, respectively. Group consensus was specified as a score of '8' or higher for ≥ 23/28 panellists. RESULTS:Eight of eleven questions and statements achieved group consensus in the first Delphi round. The remaining three questions and statements achieved group consensus in the second Delphi round, indicating more controversial topics. It was agreed that radiographs are the initial imaging technique of choice for suspected scaphoid fractures. MRI or CT are advocated for suspected radiographically occult scaphoid fractures. CT is the method of choice for assessment of osseous consolidation. Contrast-enhanced MRI is the preferred imaging modality for assessing vascularisation of scaphoid nonunion. CT is the most valuable technique in the postoperative evaluation of scaphoid fractures. CONCLUSION/CONCLUSIONS:Delphi-based consensus statements suggest imaging pathways to diagnose scaphoid fractures, assess osseous fracture consolidation and evaluate pre- and postoperative fractures. KEY POINTS/CONCLUSIONS:Question How can an international and interdisciplinary team of hand surgeons and musculoskeletal radiologists develop practical consensus statements on imaging of scaphoid fractures? Findings All eleven statements achieved group consensus among experts using the Delphi technique for consensus-building. Imaging pathways were suggested to diagnose and assess scaphoid fractures. Clinical relevance statement International, interdisciplinary and evidence-based consensus statements on imaging of scaphoid fractures were achieved using the Delphi technique. The focus of the statements was to diagnose scaphoid fractures, assess osseous fracture consolidation and evaluate pre- and postoperative fractures.
PMID: 42277387
ISSN: 1432-1084
CID: 6048732

Rapid Musculoskeletal MRI in 2026: Clinical Integration of Deep Learning Reconstruction

Vosshenrich, Jan; Fritz, Jan
Advances in MRI hardware and acceleration strategies have enabled substantial reductions in musculoskeletal MRI acquisition times over the past decade. Advanced acceleration techniques have facilitated four- to eightfold acceleration but are often limited by noise amplification and reconstruction artifacts at higher acceleration factors. The clinical introduction of deep learning (DL)-based image reconstruction addresses traditional constraints by improving SNRs, reducing artifacts, and enhancing image quality, thereby enabling higher acceleration factors than previously achievable with conventional reconstruction methods. DL reconstruction and superresolution techniques allow comprehensive musculoskeletal MRI protocols to be performed in less than 10 minutes across a range of applications, field strengths, and vendors. Successful implementation requires consideration of hardware capabilities, anatomic constraints, protocol design, and workflow adaptation to fully realize efficiency gains. In addition to technical factors, operational considerations-including scheduling logistics and infrastructure adjustments-are important to translate scan time reductions into clinical value. Early validation studies show preserved or improved diagnostic performance of DL-accelerated MRI compared with conventional protocols, supporting their growing integration into clinical practice. Continued technical development and clinical validation will further define the role of DL reconstruction and potentially facilitate even greater acceleration and efficiency gains.
PMID: 42233892
ISSN: 1546-3141
CID: 6044052

Optimizing Radiography Utilization: Multidisciplinary Expert Consensus Recommendations Endorsed by the Society of Academic Bone Radiologists, Society of Skeletal Radiology, American Society of Emergency Radiology, Orthopaedic Trauma Association, American Academy of Emergency Medicine, and American Rhinologic Society

Zandee van Rilland, Eddy D; Fayad, Laura M; Link, Thomas M; Davis, Kirkland W; Wu, Jim S; Brown, Ian P; Chang, Eric Y; Chow, Lawrence C; Desai, Shaun C; Fritz, Jan; Gatz, J David; Garner, Hillary W; Gorbachova, Tetyana; Gray, Mingyang L; Gross, Joel A; Guermazi, Ali; Ha, Patrick K; Halle, Tyler R; Hall, M Kennedy; Hanna, Tarek N; Kornblith, Aaron E; Lee, Mark A; Lopez-Ben, Robert R; Mann, Edana D; Moore, Christopher L; Obey, Mitchel R; Osgood, Greg M; Patel, Zara M; Raja, Ali S; Rendon, Juan M; Sabbatini, Amber K; Tannoury, Chadi; Yu, Joseph S; Boutin, Robert D
Radiography is an excellent first-line imaging technique for a wide range of conditions. However, there is insufficient evidence-based clinical guidance for ordering radiographic examinations in certain low-yield anatomic sites. To address this issue, a three-round modified Delphi consensus study was performed with a multidisciplinary, multi-institutional expert panel to determine the appropriate utilization of radiography at 12 often low-yield anatomic sites. The expert panel comprised 34 subspecialty faculty members (16 radiologists, nine emergency medicine physicians, four orthopedic surgeons, and five otolaryngology surgeons) from 21 academic centers. They evaluated 12 anatomic sites: rib, scapula, sacrum, coccyx, sternum, sternoclavicular joint, nasal bone, mandible, facial bones, sinuses, neck soft tissue, and skull. A structured literature review across three databases was conducted to assess the utilization and diagnostic test characteristics of radiography for each anatomic site. Teams drafted consensus statements and supporting text for their respective sites and submitted these statements to the panel for iterative rounds of anonymized voting. All 58 submitted statements achieved consensus by the end of round 3 and were endorsed by six major American medical societies. This study established expert consensus recommendations for the appropriate utilization of radiography at 12 anatomic sites through a multidisciplinary and multi-institutional deliberative process.
PMID: 42153836
ISSN: 1527-1315
CID: 6037892

New Techniques in Musculoskeletal MRI: State of the Art

Vosshenrich, Jan; Khodarahmi, Iman; Fritz, Jan
ABSTRACT/UNASSIGNED:Musculoskeletal magnetic resonance imaging has evolved substantially, driven by advances in hardware, image acquisition, and reconstruction techniques. Improvements in gradient performance and dedicated radiofrequency coils have enhanced spatial resolution and scan efficiency across field strengths. Image acceleration strategies, including parallel imaging, simultaneous multislice acquisition, and compressed sensing, now enable high-quality two-dimensional and three-dimensional magnetic resonance imaging with markedly reduced examination times and facilitate the time-neutral incorporation of advanced metal artifact reduction techniques into clinical magnetic resonance imaging protocols. ABSTRACT/UNASSIGNED:Deep learning-based reconstruction and super-resolution augmentation methods have further expanded achievable acceleration and image quality. Emerging techniques such as synthetic magnetic resonance imaging, magnetic resonance neurography, kinematic magnetic resonance imaging, and zero echo time magnetic resonance imaging expand the capabilities of musculoskeletal magnetic resonance imaging. At the same time, renewed interest in low-field magnetic resonance imaging provides intriguing opportunities to improve accessibility and sustainability. Ultra-high field magnetic resonance imaging provides unprecedented spatial resolution and quantitative insights in selected applications. These developments are redefining musculoskeletal magnetic resonance imaging practice and broadening its clinical value.
PMID: 42119689
ISSN: 1098-898x
CID: 6036662

Postmortem Analysis of Osseointegration in Cementless Acetabular Components After Total Hip Arthroplasty: A Multimodal Study

Saba, Braden V; Schaffler, Benjamin; Martins de Souza, Bruno; Schaffer, Olivia; Fallah, Cameron; Alhaddad, Noor; Montague, Michael; Fritz, Jan; Hopper, Robert; Engh, Charles A; Witek, Lukasz; Schwarzkopf, Ran
INTRODUCTION/BACKGROUND:Press-fit acetabular components achieve long-term fixation through osseointegration, yet the extent of bone ingrowth necessary for durable stability in well-functioning implants remains unclear. Postmortem retrievals provide a unique opportunity to directly assess the bone-cup interface in clinically successful total hip arthroplasties (THAs). This study evaluated osseointegration and biomechanical fixation strength in deceased-donor acetabular components to better define the characteristics of stable long-term fixation. METHODS:Cadaver pelvis specimens containing uncemented THAs from a single institution were evaluated. There were 29 acetabular components that underwent axial pull-out testing using a universal testing machine. A total of seven of these were additionally processed for histologic evaluation, including dehydration, acrylic embedding, thin-sectioning, staining, and digital imaging. Osseointegration was quantified by bone-area fraction occupancy (%BAFO), representing the proportion of bone occupying the porous thread spaces of the cup. RESULTS:All 29 specimens failed through fracture of the ilium rather than at the bone-cup interface, indicating that the mechanical integrity of the osseointegrated construct exceeded that of the surrounding bone under axial tension. Among the seven histologically analyzed components, %BAFO ranged from 4.2 to 27.0% (mean 15.1%), despite all implants being clinically stable at the time of death. There were no significant linear correlations observed between %BAFO and time implanted, fracture load, or body mass index. A significant quadratic relationship between %BAFO and age was identified, peaking near 81 years. CONCLUSIONS:Cementless acetabular components exhibited strong fixation despite modest osseointegration, with failure occurring through host bone on axial testing. Durable biological fixation appears achievable with limited, but mechanically favorable bone ingrowth.
PMID: 42069020
ISSN: 1532-8406
CID: 6029862

[When Greek mythology entered radiology: Cyclops lesions in the knee]

Horger, Marius; Gohla, Georg; Fritz, Jan; Gonser, Christoph Emanuel; Ruff, Christer; Heckl, Stefan
PMID: 42049065
ISSN: 1438-9010
CID: 6029172

Best fast MRI protocols for the knee: advantages and limitations

Leonhardt, Yannik; Vosshenrich, Jan; Fritz, Jan
Knee MRI plays a central role in musculoskeletal diagnostics but has traditionally been associated with relatively long acquisition times. Recent technological advances have fundamentally changed this paradigm. Parallel imaging (PI), simultaneous multi-slice acquisition (SMS), compressed sensing (CS), and combinations thereof have substantially reduced scan times without compromising diagnostic image quality. The introduction of deep learning (DL)-based reconstruction further elevates this transformative breakthrough, as it can reconstruct high-quality diagnostic MR images at higher acceleration factors, where conventional image reconstruction methods have traditionally struggled to succeed. Sixfold PIxSMS-accelerated DL protocols have demonstrated excellent diagnostic performance and image quality, allowing comprehensive knee MRI examinations to be completed in under five minutes. Accelerated three-dimensional (3D) TSE techniques, such as CAIPIRINHA-accelerated SPACE sequences, further expand the potential of knee MRI by enabling high-resolution isotropic 3D imaging at acquisition times that are increasingly practical for routine clinical use. Ongoing improvements in DL-based reconstruction and denoising may soon bridge the remaining gap, promising to enable the acquisition of isotropic 3D datasets with multiple contrasts within minutes. Beyond technical acceleration, the successful implementation of fast MRI requires careful workflow optimization and consideration of architectural and economic factors. This review outlines the technical principles underlying modern acceleration strategies, summarizes evidence from validation studies, discusses practical aspects of clinical implementation and protocol optimization, and highlights future opportunities and challenges.
PMID: 41874638
ISSN: 1432-2161
CID: 6018032

How I Do It: Fast MRI of the Joints

Vosshenrich, Jan; Fritz, Jan
This article provides a practice-oriented overview of current concepts in rapid musculoskeletal MRI of central and peripheral joints, focusing on echo train optimization and the application of modern acceleration techniques. Parallel imaging, simultaneous multislice acquisition, and compressed sensing-based undersampling can be applied independently or in combination to expedite MRI of the joints. Clinically available three- to eightfold acceleration of two-dimensional (2D) and three-dimensional turbo spin-echo (TSE) pulse sequences enables comprehensive 5-10-minute MRI protocols of joints. This acceleration allows for the efficient integration of advanced metal artifact reduction techniques into clinical MRI protocols. When conventional image reconstruction techniques fail, clinically available deep learning-based image reconstruction and superresolution augmentation methods effectively reconstruct images from highly accelerated acquisitions. Together, moderate acceleration and advanced image reconstruction techniques provide high diagnostic image quality of heavily undersampled MRI data, enabling three- to sixfold accelerated 2D TSE MRI of multiple joints in 4-6 minutes. Recent studies indicate that specially designed and trained deep learning methods may achieve 10-fold accelerated musculoskeletal MRI, with acquisition times under 3 minutes. Although further research and data are necessary, these promising developments are poised to enhance the value of musculoskeletal MRI.
PMID: 41842665
ISSN: 1527-1315
CID: 6016552

What's New: Sub-5-minute Knee Magnetic Resonance Imaging- Spectrum of Sports Injuries and Overuse Conditions

Leung, Sophie; Fritz, Jan
Knee injuries are one of the most common complaints in sports medicine. Magnetic resonance imaging is an essential adjunct to clinical evaluation for many traumatic injuries and overuse conditions. Given the heavy use of knee magnetic resonance imaging, developing faster magnetic resonance imaging acquisition methods and deployment in clinical practice would be valuable. In this article, we illustrate a spectrum of knee abnormalities from our clinical practice, utilizing a recently developed, publicly available sub-5-minute knee magnetic resonance imaging protocol with super-resolution image reconstruction based on deep learning. We review common traumatic injuries and overuse conditions of the knee and illustrate cases with this novel fast knee magnetic resonance imaging protocol.
PMID: 41776842
ISSN: 1098-898x
CID: 6008742

Interventional Management of Pain with Cryoneurolysis: Expert Consensus Recommendations for Standardizing Patient Selection and Techniques Based on Delphi Process

Cornelis, Francois H; Resnick, Neil J; Barral, Matthias; Bauones, Salem; Fritz, Jan; Guenette, Jeffrey P; Jennings, Jack W; Kastler, Adrian; Kelekis, Alexis; Levey, Alexa; Garcia Marcos, Raul; Moussa, Marwan; Petsatodis, Evangelos; Pua, Uei; Ramalingam, Vijay; Razakamanantsoa, Leo; Sag, Alan A; Stacoffe, Nicolas; Tutton, Sean; Yevich, Steven; Prologo, J David; Filippiadis, Dimitrios
PURPOSE/OBJECTIVE:To develop expert consensus recommendations for patient selection and procedural techniques in cryoneurolysis for chronic pain management using a Delphi process. MATERIALS AND METHODS/METHODS:A panel of 22 international interventionists participated in a two-round Delphi process. Participants rated 42 statements on a 10-point Likert scale (1 = strongly disagree, 10 = strongly agree). Consensus was predefined as ≥ 75% of ratings ≥ 7. Descriptive statistics (n, mean ± SD, % ≥ 7) were calculated. RESULTS:High agreement supported cryoneurolysis for localized chronic pain refractory to conservative therapies (mean 8.55 ± 0.60; 100% ≥ 7) and cases with identifiable peripheral nerve targets (8.45 ± 0.74; 100% ≥ 7). Imaging guidance was deemed essential for nerve identification and probe placement (8.91 ± 0.29; 100% ≥ 7). The panel endorsed individualized freeze-thaw cycles to achieve Sunderland II injury (8.27 ± 0.83; 91% ≥ 7) and emphasized thorough patient education (9.0 ± 0.0; 100% ≥ 7). Experts recommended repeat cryoneurolysis within weeks if initial response was incomplete (8.64 ± 0.65; 100% ≥ 7) and alternative therapies after two unsuccessful sessions (8.36 ± 0.73; 95% ≥ 7). No consensus was reached on restricting treatment to a single anatomical region (5.82 ± 2.91; 50% ≥ 7) or routine prophylactic antibiotics (6.27 ± 2.57; 54% ≥ 7). CONCLUSION/CONCLUSIONS:This Delphi study establishes expert-derived consensus standards for cryoneurolysis, highlighting careful patient selection, mandatory imaging guidance, and flexible freeze protocols while identifying areas requiring further research.
PMID: 41457159
ISSN: 1432-086x
CID: 6000932