Searched for: in-biosketch:true
person:martim64
Integrating Patient-Reported Outcome Measures in Atopic Dermatitis Clinical Practice: An Analysis of the Patient-Oriented Eczema Measure
Obijiofor, Chinemelum E; Martinez, Michael; Chappidi, Rayvanth; Friedman, Steven; Mandal, Soutrik; Adotama, Prince; Oza, Vikash
The Patient-Oriented Eczema Measure (POEM) is a validated patient-reported outcome measure for atopic dermatitis (AD), though its use in routine pediatric dermatology practice remains underexplored. In this cross-sectional study of 297 pediatric patients with AD at a tertiary pediatric dermatology clinic, POEM scores were collected and compared with physician-rated investigator global assessment (IGA) and IGA × body surface area, as well as treatment selection. Older patients (> 12 years) had significantly higher mean POEM scores (17.5 vs. 10.4; p < 0.001) with no significant differences observed by race, ethnicity, or socioeconomic status; total POEM scores correlated strongly with IGA (r = 0.68) and moderately with IGA×BSA (r = 0.54), and higher severity scores were associated with more potent topical corticosteroids and systemic treatments (p < 0.001). POEM detected clinically relevant changes, aligned with physician-rated measures, and correlated with treatment intensity, underscoring its utility in both clinical practice and future predictive modeling applications.
PMID: 42080414
ISSN: 1525-1470
CID: 6030862
Good Practice Concepts in Pediatric Critical Care Point-of-Care Ultrasound: A Modified Delphi Consensus Initiative
Penk, Jamie S; Bhargava, Vidit; Chandnani, Harsha; Chong, Grace; Conlon, Thomas; DeSanti, Ryan L; Diddle, J Wesley; Floh, Alejandro; Flores, Saul; Hsieh, Anyir; Kantor, David; Kaplan, Daniel; Kozyak, Benjamin; Li, Boran; Lumpkin, Christopher; MacDonald, Jennifer; Maxson, Ivanna; Nishisaki, Akira; Patel, Meghna D; Riggs, Becky J; Rivera, Michael Lintner; Martinez, Michael; Mills, Marcos; RamÃrez, Michelle; Tripathi, Sandeep; Veten, Ahmed; Vijayakumar, Niranjan; Wenger, Jesse; Werho, David K; Su, Erik; Al-Subu, Awni; ,
OBJECTIVE:We assembled a workgroup within the Pediatric Research Collaborative on Critical UltraSound (PeRCCUS), a subgroup of the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), to define early guidance for point-of-care ultrasound (POCUS) institutional practice and foster future comprehensive guidelines for its broad adoption in pediatric critical care medicine. DESIGN/METHODS:A modified Delphi method was used for creating the statements. The first meeting was an open proposal session for workgroup members to suggest items for consideration. This was followed by a cycle of voting for levels of agreement along a 7-point Likert-type scale. Items were reviewed, with only items receiving a score of greater than or equal to 6 progressing to the next stage of voting and lower-scoring items reconsidered, with only consensus items proceeding to the next stage for additional rounds of voting until consensus was reached. SETTING/METHODS:Multi-institutional, multidisciplinary, workgroup of experts on POCUS organized within PeRCCUS as a subgroup of PALISI. INTERVENTIONS/METHODS:None. MEASUREMENTS AND MAIN RESULTS/RESULTS:Consensus was obtained for 25 recommendations across five domains: clinical application, quality assurance, equipment, education, and research. CONCLUSIONS:We report consensus recommendations for institutions on clinical use, educational programs, quality assurance, technical requirements, and future research opportunities for the adoption of pediatric critical care medicine POCUS.
PMID: 41642060
ISSN: 1529-7535
CID: 6000342
Reduced Perioperative Bleeding With Use of Saphenous Vein Homograft as Blalock-Taussig-Thomas Shunt
Kumar, T K Susheel; Pasternack, Daniel M; Crawford, Maya T; Beaulieu, Thomas; Martinez, Michael J; Chakravarti, Sujata; Bull, Catherine; Vlassis, Isabella M; James, Leslie; Staffa, Steven J; Zurakowski, David; Mosca, Ralph
BACKGROUND/UNASSIGNED:Polytetrafluoroethylene (PTFE), traditionally used for construction of Blalock-Taussig-Thomas (BTT) shunt, is associated with complications such as perioperative bleeding, thrombosis, and stenosis. Saphenous vein homografts (SVHs) are theoretically more hemostatic and less thrombogenic. METHODS/UNASSIGNED:A retrospective chart review was conducted of all infants who underwent BTT shunt placement between January 2015 and May 2023 to compare the use of blood and blood products in the operating room and within the first 24 hours after cardiac intensive care unit admission. Morbidity (unplanned reoperations, extracorporeal membrane oxygenation requirement, or dialysis) was also compared. RESULTS/UNASSIGNED:= .004) with SVH. There were no group differences in rate of shunt thrombosis or need for percutaneous intervention. Interstage mortality (8% vs 13%) and morbidity (8% vs 10%) were similar, as were hemodynamic data before shunt takedown. CONCLUSIONS/UNASSIGNED:SVH as BTT shunt is associated with significantly less perioperative bleeding compared with PTFE, with no differences in risk of thrombosis or need for percutaneous intervention.
PMCID:12712163
PMID: 41425448
ISSN: 2772-9931
CID: 6041802
Rare coronary anomaly in association with tetralogy of Fallot and absent pulmonary valve [Case Report]
Kumar, T K Susheel; Underill, Zoe; Harrison, Cynthia; Chakravarti, Sujata B; Martinez, Michael J; Argilla, Michael; Mosca, Ralph
PMCID:12237772
PMID: 40641754
ISSN: 2666-2507
CID: 5891192
Severe hyperlactatemia from Warburg effect due to post-transplant lymphoproliferative disorder after paediatric heart transplantation with resolution following thiamine administration
Martinez, Michael J; St Francis, Hannah; Contreras Yametti, Gloria; Biary, Rana; Singh, Rakesh K
Hyperlactatemia is a common and concerning finding in the paediatric cardiac ICU as it may signify tissue hypoperfusion and/or hypoxia. However, it is important to include other aetiologies for an elevated lactate in the differential, especially when the lactate is significantly elevated (> 8 mmol/L). We present the case of metabolic acidosis with severe hyperlactatemia secondary to Warburg effect and presumed thiamine deficiency in a paediatric heart transplant patient with post-transplant lymphoproliferative disorder.
PMID: 40394735
ISSN: 1467-1107
CID: 5853062
Sexual orientation and gender identity in clinical trials of atopic dermatitis and psoriasis [Letter]
Martinez, Michael J; Rabbin-Birnbaum, Corinne; Yeung, Howa; Zampella, John G
PMID: 40365854
ISSN: 1468-3083
CID: 5844342
Cutaneous Disease of Penoscrotal Skin Part II: Infectious and Inflammatory Dermatoses
Martinez, Michael J; Oh, Christina S; Young, Trevor; Meehan, Shane; Hall, Anthony; Zampella, John G
PMID: 39106926
ISSN: 1097-6787
CID: 5730612
Cutaneous Disease of Penoscrotal Skin Part I: Benign and Neoplastic Lesions
Martinez, Michael J; Oh, Christina S; Young, Trevor; Meehan, Shane; Hall, Anthony; Zampella, John G
Penoscrotal skin diseases encompass an array of pathologies that present with unique clinical features. A patient-tailored approach to management is necessary. This article, part of a continuing medical education series, is dedicated to offering insights for managing penoscrotal dermatoses. The first article will provide an overview of normal variations, benign lesions, and malignant growths. We will then highlight up-to-date diagnostic and treatment protocols. In the second article, we will discuss inflammatory and infectious conditions, reviewing common diseases such as syphilis, human papilloma virus, and psoriasis, as well as rarer, difficult to treat diseases such as lichen sclerosus, lichen planus, and genital dyesthesias. Considering 70% of patients with genital skin diseases report that physicians lack awareness of these conditions,1 this CME series will help practitioners identify penoscrotal diseases, expand differential diagnoses, and discuss appropriate and emerging therapies.
PMID: 39103122
ISSN: 1097-6787
CID: 5730552
Minimally Invasive Injectable Cosmetic Procedures Increase Feelings of Authenticity
Martinez, Michael J; White, Michael W; Bailey, Erica R; Smeallie, Eleanor; Hoffman, Lauren; You, Janet; Chapas, Anne M; Lee, Nayoung; Iyengar, Sheena; Rieder, Evan A
BACKGROUND:Minimally invasive cosmetic dermatology procedures continue to be increasingly popular; however, the extant literature has poorly documented the psychological antecedents of interest in cosmetic procedures and their psychological consequences. OBJECTIVE:To better inform dermatologists on their patients' motivations for cosmetic enhancement. MATERIALS AND METHODS/METHODS:In a general population survey, an online representative sample of 984 Americans reported the extent to which they feel authentic using the validated authenticity scale and whether they were interested in undergoing a cosmetic procedure. In a prospective dermatology office survey, 102 participants reported their feelings of authenticity immediately before and 2 weeks after receiving a minimally invasive injectable cosmetic procedure. RESULTS:In the general population survey, participants interested in cosmetic procedures felt significantly less authentic than participants who were not interested ( p = .003). In the prospective dermatology office survey, participants felt significantly more authentic 2 weeks after their minimally invasive injectable cosmetic procedure than before ( p = .018). CONCLUSION/CONCLUSIONS:Lower feelings of authenticity are associated with interest in cosmetic procedures. Participants felt more authentic 2 weeks after receiving a minimally invasive injectable cosmetic procedure. Cosmetic procedures may present patients with an opportunity to feel more like their real, genuine selves.
PMID: 39074157
ISSN: 1524-4725
CID: 5696282
Correction: Predictors for the use of systemic therapy in stage IB Mycosis fungoides
Rodriguez, Elijah; Needle, Carli D; Martinez, Michael J; Nohria, Ambika; Xing, Yiping; Song, Clara; Betensky, Rebecca; Latkowski, Jo-Ann; Adotama, Prince
PMID: 39080081
ISSN: 1432-069x
CID: 5696392