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Impact of Social and Behavioral Determinants on Utilization and Outcomes of Total Ankle Arthroplasty: A Systematic Review
Tham, Alexander; Calton, Megan; Rubin, Jared; Mainville, Anaelie; Walls, Raymond; Schafer, Kevin A; Schon, Lew C; Kennedy, John G
BACKGROUND:Total ankle arthroplasty (TAA) provides pain relief and motion preservation for end-stage ankle arthritis, yet outcomes and utilization vary widely. Social determinants of health (SDOHs) such as socioeconomic, demographic, and behavioral factors may contribute to these disparities, but their influence on TAA has not been systematically evaluated. METHODS:A systematic review was registered on PROSPERO (CRD420251156933) and performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using the PROGRESS-Plus framework to identify studies examining the impact of SDOH on TAA utilization and outcomes. PubMed, Embase, and Scopus were searched through 2025. Study quality was assessed with the Risk Of Bias In Nonrandomized Studies of Interventions tool, and certainty of evidence for each domain was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation framework. Data were synthesized narratively with random-effects meta-analysis where feasible. RESULTS:Forty-four studies including more than 200,000 patients were analyzed. Social determinants were found to influence both access to TAA and postoperative outcomes. Men demonstrated slightly better postoperative function, whereas women reported more pain and higher rates of nonhome discharge. Older patients experienced more perioperative complications but achieved similar long-term implant survival compared with younger cohorts. Patients from minority racial and ethnic groups had higher complication rates and were less likely to receive TAA compared with arthrodesis. Lower income, public insurance, and treatment in rural or lower-volume hospitals were consistently linked with reduced access to TAA, longer hospital stays, and greater healthcare costs. Behavioral factors such as smoking and preoperative opioid use were strongly associated with wound complications, prolonged hospitalization, and poorer recovery. CONCLUSION/CONCLUSIONS:SDOH significantly shape access to surgery, complication risk, and recovery after TAA. Recognition of these influences and targeted strategies such as preoperative optimization, equitable referral pathways, and improved access to rehabilitation may help reduce disparities and improve outcomes in ankle arthroplasty. LEVEL OF EVIDENCE/METHODS:Level III, systematic review of predominantly Level III studies.
PMID: 41662479
ISSN: 2329-9185
CID: 6001772
Patient-Specific vs Standard Instrumentation in Total Ankle Arthroplasty: A Systematic Review and Meta-analysis of Short-term Outcomes
Tham, Alexander; Rubin, Jared; Bieganowski, Thomas; Butler, James J; Konar, Kishore; Walls, Raymond J; Schon, Lew C; Kennedy, John G
BACKGROUND:Patient-specific instrumentation (PSI) has been proposed to improve accuracy and efficiency in total ankle arthroplasty (TAA). Although cadaveric studies suggest improved precision, the clinical value of PSI over standard instrumentation (SI) remains uncertain. METHODS:A systematic review and meta-analysis following PRISMA guidelines was performed using PubMed, Embase, and Cochrane databases through July 2025. Comparative studies evaluating PSI vs SI in TAA were included. Outcomes analyzed included patient-reported outcome measures (PROMs), radiologic alignment, intraoperative efficiency, complication and revision rates, and cost. Random effects models were used to pool standardized or mean differences (MDs) or risk ratios with 95% CIs. RESULTS: < .001). No statistically significant differences were detected in complication and revision rates. Cost analysis produced conflicting results, with one study suggesting potential savings and another finding PSI more expensive after accounting for preoperative imaging. CONCLUSION/CONCLUSIONS:PSI in TAA reduces fluoroscopy time but does not appear to enhance functional outcomes, complication rates, or revision risk compared with SI in the short term. PSI may result in greater deviation from sagittal alignment, and its cost-effectiveness remains uncertain. High-quality prospective studies with long-term follow-up are needed to clarify its role in routine and complex cases.
PMID: 41589398
ISSN: 1944-7876
CID: 6003152
Needle arthroscopy for the management of foot and ankle pathology [Historical Article]
Dankert, John F; Butler, James J; Walls, Raymond; Kennedy, John G
Needle arthroscopy is a minimally invasive technique available for the management of common foot and ankle pathologies. Owing to the limitations associated with first-generation needle arthroscopic models, specifically visualization and fluid management, needle arthroscopy has undergone revitalization over the past decade. Newer systems are now using chip on tip visualization capability as well as improved fluid pumps allowing for direct intervention under improved visualization. The smaller diameter of the needle arthroscope permits procedures to be conducted in both the operating room and office setting under wide-awake conditions. We present this review to detail the history of needle arthroscopy and highlight how needle arthroscopy has improved care for patients with foot and ankle disorders.
PMCID:12742492
PMID: 41637598
ISSN: 2328-5273
CID: 6000052
Isolated Fifth Metatarsal Fractures: A Spectrum of Patterns With Similar Clinical and Radiographic Outcomes Regardless of Management
Kadiyala, Manasa L; Kingery, Matthew T; Walls, Raymond; Leucht, Philipp; Ganta, Abhishek; Konda, Sanjit R; Egol, Kenneth A
INTRODUCTION/BACKGROUND:Several types of fifth metatarsal (MT) fractures exist and are treated with various methods of immobilization, weight bearing restrictions, and occasionally operative procedures. This study evaluated the differences in clinical and radiographic outcomes among pseudo-Jones fractures (Zones 1 and 2), true Jones fractures (Zone 3), and fifth metatarsal shaft and neck fractures. METHODS:A retrospective review of a consecutive series of patients presenting to a single academic medical center with a fifth metatarsal fracture between 2012 and 2022 was conducted. Radiographs obtained at the initial presentation were reviewed, and fracture patterns were categorized as either Zone 1, Zone 2, Zone 3, shaft, neck, or head fractures. RESULTS:In total, 1314 patients with isolated fifth metatarsal fractures were treated (mean age = 49.6 ± 18.0 years). In total, 1217 fractures (92.5%) were initially treated nonoperatively, and 97 fractures (7.5%) were treated operatively. The overall time to clinical and radiographic healing for all fifth metatarsal fractures treated nonoperatively was 9.9 ± 8.7 weeks and 17.9 ± 15.6 weeks, respectively (P = .245, P = .088). Immediate weightbearing led to a faster time to clinical healing by (P = .035). There was no statistically significant difference in time to clinical or radiographic union among the different fracture types (P = .496, P = .400). Likewise, there was no evidence of any difference in time to clinical or radiographic union for patients treated operatively versus nonoperatively (P > .05). CONCLUSION/CONCLUSIONS:.
PMID: 40968738
ISSN: 1938-7636
CID: 5935532
The impact of mental health disorders on outcomes following total ankle arthroplasty: A systematic review
Mercer, Nathaniel P; Lezak, Bradley A; Hedbany, Davis; Butler, James J; Krebsbach, Sebastian; Bloom, David A; Harrington, Michael; Rosenbaum, Andrew J; Walls, Raymond J; Kennedy, John G
BACKGROUND:The purpose of this systematic review was to evaluate the impact of mental health disorders (MHDs) on the clinical and functional outcomes following total ankle arthroplasty (TAA) for the treatment of end-stage ankle arthritis. METHODS:A systematic review of the EMBASE, MEDLINE, and Cochrane Library databases was conducted in April 2024 following PRISMA guidelines. Data collected included patient demographics, clinical outcomes, complications, and failures. RESULTS:Six studies published between 2019 and 2023 were included, involving a total of 8772 patients who underwent TAA. Among these, 1076 patients (12.3 %) had a pre-operative MHD. The weighted mean age was 64.1 ± 4.9 years, and the mean postoperative follow-up was 4.6 ± 7.2 months. There were inferior subjective clinical outcomes in patients with an associated MHD, as demonstrated by lower scores in the Self-Administered Foot Evaluation Questionnaire (SAFE-Q), Visual Analogue Scale (VAS), and American Orthopaedic Foot and Ankle Society (AOFAS) scores compared to patients without a MHD. Additionally, patients with MHDs had high complication rates (23.7 %), including 76 prosthetic complications (6.1 %) and 15 cases (1.2 %) requiring revision procedures. However, no significant differences in objective outcomes such as joint mobility or implant failure rates were found between those with and without MHDs. CONCLUSION/CONCLUSIONS:MHDs adversely affect subjective outcomes and complications following TAA, highlighting the need for integrated mental health management in preoperative and postoperative care. Further research is needed to understand the precise role of mental health in TAA outcomes.
PMID: 39818473
ISSN: 1460-9584
CID: 5777112
A Historical Perspective of Surgical Procedures Used in the Treatment of Hallux Valgus: A Contemporary Review
Ubillus, Hugo A; Bi, Andrew S; Fisher, Nina D; Jimenez Mosquea, Thelma R; Walls, Raymond J
Visual AbstractThis is a visual representation of the abstract.
PMCID:12126636
PMID: 40453510
ISSN: 2473-0114
CID: 5862002
Revision Surgery for Failed Polyvinyl Alcohol Hydrogel Implant in the First MTP Joint: A Case Report and Comprehensive Review
Jimenez Mosquea, Thelma R; Colasanti, Christopher A; Ubillus, Hugo A; Walls, Raymond J
BACKGROUND/UNASSIGNED:Hallux rigidus is a degenerative condition of the first metatarsophalangeal (MTP) joint that can significantly impair function and quality of life. The introduction of polyvinyl alcohol (PVA) hydrogel implants, such as Cartiva, offered an alternative to arthrodesis by preserving joint motion. However, failures of these implants, often resulting in bone loss and joint instability, present a challenge for revision surgery. METHODS/UNASSIGNED:We report the case of a 43-year-old woman with persistent pain and functional limitations after a failed PVA hydrogel implant in the first MTP joint. The revision surgery involved a biologic resurfacing using the Osteochondral Autograft Transfer System (OATS) with a graft harvested from the ipsilateral femoral condyle, complemented by interpositional arthroplasty with a dermal graft and a proximal phalanx closing wedge osteotomy to correct residual hallux valgus. RESULTS/UNASSIGNED:At the 3-year follow-up, the patient-reported complete resolution of pain and returned to full activity with improved range of motion (40 degrees dorsiflexion, 15 degrees plantarflexion). Radiographic evaluation demonstrated graft incorporation and restoration of joint space, confirming the success of the procedure. CONCLUSION/UNASSIGNED:This case highlights the potential of OATS combined with interpositional arthroplasty as a viable option for revision surgery in complex cases of failed synthetic cartilage implants in hallux rigidus. By addressing bone loss and preserving joint function, this approach provides a patient-specific alternative to traditional arthrodesis. Further studies are warranted to establish the long-term efficacy of this technique in similar cases. LEVEL OF EVIDENCE/UNASSIGNED:Level V, case report.
PMCID:12033773
PMID: 40297397
ISSN: 2473-0114
CID: 5833382
Standing on the Heels of Giants: A Historical Perspective of Eponyms for Calcaneal Osteotomies
Jimenez Mosquea, Thelma R; Bi, Andrew S; Fisher, Nina D; Ubillus, Hugo A; Walls, Raymond J
PMCID:11603546
PMID: 39610645
ISSN: 2473-0114
CID: 5804052
Effect of patient age on fifth metatarsal fracture pattern, management, and outcomes
Kadiyala, Manasa L; Kingery, Matthew T; Walls, Raymond; Ganta, Abhishek; Konda, Sanjit R; Egol, Kenneth A
Patients with 5th metatarsal (MT) fractures encompass a broad age distribution. This study evaluated the impact of age on the differences in clinical outcomes and management of these fractures. This was a retrospective cohort study of patients presenting to a single large, urban, academic hospital system with a 5th MT fracture over a 10-year period. Patients were stratified into groups of younger than 65 years old and equal to or greater than 65 years old. Initial and successive radiographs were reviewed, and fractures were categorized as Zone 1, Zone 2, Zone 3, Shaft, Neck, or Head fractures. 2,461 patients with 5th MT fractures were evaluated. Patients who did not follow up after initial evaluation in the emergency department or urgent care were excluded. Among 2,020 patients with mean follow-up of 1.03 years who met inclusion criteria, 76.2% were younger than 65 years and 23.8% were greater than or equal to 65 years. There was a significant difference in fracture type between groups as older patients were more likely to sustain metatarsal neck fractures but less likely to sustain Zone 1 base fractures (p < 0.05). There was no difference in time to clinical healing (p = 0.108) or time to radiographic union (p = 0.367) for all fractures between age groups. In conclusion, older patients sustain different 5th metatarsal fracture patterns compared to younger patients. However, despite the differences in age, there was no evidence for any difference in clinical and radiographic outcomes between groups.
PMID: 39245432
ISSN: 1542-2224
CID: 5689922
Management of zone 2 fifth metatarsal fractures varies based on treating specialty
Kingery, Matthew T; Kadiyala, Manasa L; Walls, Raymond; Ganta, Abhishek; Konda, Sanjit R; Egol, Kenneth A
AIMS/UNASSIGNED:This study evaluated the effect of treating clinician speciality on management of zone 2 fifth metatarsal fractures. METHODS/UNASSIGNED:(SD 6.0)) with a mean follow-up duration of 2.57 years (SD 2.64). RESULTS/UNASSIGNED:Overall, 281 patients (57.7%) were treated by orthopaedic surgeons, and 206 patients (42.3%) by podiatrists. When controlling for age, sex, and time between symptom onset and presentation, the likelihood of undergoing operative treatment was significantly greater when treated by a podiatrist (odds ratio (OR) 2.9 (95% CI 1.2 to 8.2); p = 0.029). A greater proportion of patients treated by orthopaedic surgeons were allowed to immediately bear weight on the injured foot (70.9% (178/251) vs 47.3% (71/150); p < 0.001). Patients treated by podiatrists were immobilized for significantly longer (mean 8.4 weeks (SD 5.7) vs 6.8 weeks (SD 4.3); p = 0.002) and experienced a significantly longer mean time to clinical healing (12.1 (SD 10.6) vs 9.0 weeks (SD 7.3), p = 0.003). CONCLUSION/UNASSIGNED:Although there was considerable heterogeneity among zone 2 fracture management, orthopaedic surgeons were less likely to treat patients operatively and more likely to allow early full weightbearing compared to podiatrists.
PMID: 39216866
ISSN: 2049-4408
CID: 5687522