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What do youth need to know about puberty? A scoping review protocol to identify puberty education competencies
Brault, Marie A; Singh, Nanki; Kakkad, Nikita; Peskin, Melissa; Betori, Anthony; Laynor, Gregory; Naiser, Emily
INTRODUCTION/BACKGROUND:Puberty is a key transition point in adolescents' lives that plays a foundational role in shaping health behaviors and outcomes across one's life course. This period holds significant potential to empower adolescents and support autonomy in health and well-being, but limited puberty education curricula exist for early adolescents (age 8-14), and those that do exist vary in content. There is a paucity of evaluations of puberty competencies and limited consensus on what competencies should be measured to assess effectiveness or even how to measure these competencies. OBJECTIVE:The objective of this scoping review is to systematically map and characterize the outcomes, domains, and instruments used to evaluate puberty education curricula for early adolescents aged 8-14 years. In accordance with PRISMA-ScR and JBI scoping review guidance, this review does not synthesize effect sizes or assess intervention efficacy, but maps the breadth of evidence to identify conceptual gaps and inform future framework development. METHODS:The review protocol is registered with the Open Science Framework (OSF). We will search PubMed, CINAHL, PsycInfo, ERIC, Education Source, Scopus, Web of Science Core Collection, ProQuest Dissertations and Theses Global, and OpenAlex for relevant sources. Two reviewers will independently screen and extract studies that meet inclusion criteria using our data extraction tool. EXPECTED OUTPUTS/UNASSIGNED:Findings from the scoping review will be synthesized to create an overarching framework that can guide approaches to the development and evaluation of puberty curricula targeted to early adolescents. Focus group discussions with adolescents, parents, and school representatives will be conducted to assess the applicability and appropriateness of identified competencies and evaluation measures prior to broader dissemination. Insights from this scoping review will ultimately be used to inform the implementation and evaluation of puberty education.
PMCID:13249200
PMID: 42263087
ISSN: 1932-6203
CID: 6048292
Diet in the General United States Asian American Population: A Scoping Review
Chan, Sze Wan Celine; Godbole, Neel; LeCroy, Madison N; Kuang, Katherine M; Cheng, Jessica; Beasley, Jeannette M; Laynor, Gregory; Wang, Vivian Hsing-Chun; Ali, Shahmir H; Yi, Stella S
Asian American populations are underrepresented within dietary programs and nutrition-specific funding. Existing understanding amongst Asian American communities focuses on those with pre-existing health conditions. There is a gap in published literature providing an overview of the food groups Asian American populations without noncommunicable diseases consume. This scoping review aims to provide a comprehensive mapping of the Asian American diet with a focus on food groups in the United States within existing literature. A scoping review was conducted from December 2023 to December 2024. Research databases (PubMed/Medline, CABI Digital Library, CINAHL, Scopus, Web of Science, EBSCO, and ProQuest Dissertations) were searched to identify articles published since 2000 that described food group consumption of Asian American populations. A total of 1486 articles were independently screened by 3 reviewers, leaving 165 articles for inclusion in this review. An additional 15 gray literature sources were separately reviewed for complementary information. Key findings (population and geographical focus, dataset, food group outcome, study limitations, and recommendations) were extracted and summarized in narrative form. Within the literature, Asian American adults and children generally consume more refined grains and less dairy than the standard United States population, though specific patterns vary: South Asians report higher saturated fat and dairy intake, while Chinese, Filipino, and Southeast Asian groups often fall short of recommended fruit and vegetable consumption. Dietary staples also differ by ethnicity, ranging from white rice and noodles in East/Southeast Asian diets to breads and buns among South Asian and Filipino communities. Recommendations for improving diets in Asian American communities emphasize culturally tailored nutrition education that incorporates traditional diets, promotes whole-grain substitutions, and adopts family-focused approaches. Future research efforts in Asian American diet and nutrition should better understand meal-sharing practices and cooking methods. Identifying broad insights in Asian American dietary consumption lays an essential framework for developing recommendations and interventions to address dietary behaviors contributing to diet-related disease burden among the Asian American population. This scoping review is registered on Open Science Framework (https://doi.org/10.17605/OSF.IO/K3X8S).
PMCID:13194642
PMID: 42180656
ISSN: 2475-2991
CID: 6039242
Implementing substance use services into acute care settings for pregnant and birthing people: A systematic scoping review of implementation and quality improvement strategies
King, Carla; Fawole, Adetayo; Laynor, Gregory; McNeely, Jennifer; Terplan, Mishka; Lee, Matthew; Choi, Sugy
Pregnant and birthing people with untreated substance use disorders (SUDs) face multiple risks of mortality and morbidity. Acute care settings (i.e., hospital inpatient, labor/delivery and emergency departments) are one opportunity to provide substance use services, but have had limited implementation. This scoping review synthesized studies that used an implementation science or quality improvement (QI) strategy to implement substance use services into acute care settings for pregnant or birthing people. Our aim was to 1) characterize the implemented strategies; 2) assess the inclusion of racial equity in study design and implementation; 3) summarize measures and outcomes used to evaluate implementation; and 4) identify reported barriers and facilitators to implementation. We searched MEDLINE (PubMed), CINAHL Complete (EBSCO), Scopus (Elsevier), and APA PsycINFO (Ovid) for published studies using keywords and structured vocabulary, and supplemented database searches with a grey literature search of conference proceedings. Two authors independently screened then extracted studies that met eligibility criteria. After removing 661 duplicates, we screened 1101 studies by title and abstract and excluded 1037. Thirty-six were excluded after full text review yielding 28 studies for extraction. Studies were observational (n = 20, 71%), QI (n = 7, 25%), and experimental (n = 1, 4%). Twenty (71%) focused on SUDs broadly; 8 (29%) targeted OUD. Five strategy types were identified: 1) education and learning collaboratives (n = 11, 39%); 2) clinical workflows and pathways (n = 7, 25%); 3) brief interventions (n = 2, 7%); 4) peer support (n = 4, 14%); and 5) structural changes (n = 4, 14%). Five studies (18%) considered racial and ethnic equity in design or implementation. Overall, studies highlight promising strategies to implement substance use services for pregnant and birthing people in acute care settings. However, many strategies were not rigorously evaluated and few considered racial and ethnic equity in design or implementation. Future research should focus on more rigorous evaluations of implementation strategies, measure downstream outcomes such as adoption and sustained use of substance use services, and apply a racial equity lens more explicitly.
PMCID:12987426
PMID: 41824393
ISSN: 1932-6203
CID: 6016082
Harm reduction services and interventions for People Who Use Drugs (PWUD) in Latin America and the Caribbean (LAC) between 2013-2024: A scoping review protocol
Bórquez, Ignacio; Bailey, Katie; Laynor, Gregory; Toledo, Lidiane; Bastos, Francisco I; Santaella-Tenorio, Julian; Castillo-Carniglia, Álvaro; Cerdá, Magdalena; Krawczyk, Noa
INTRODUCTION/BACKGROUND:In Latin America and the Caribbean (LAC) the response to substance use has primarily been abstinence-based, acute-care-oriented treatments. While harm reduction services (HRS) and interventions have expanded in LAC over the last decade, the research evidence on such programs has been sparse and disjointed. OBJECTIVE:This scoping review will map peer-reviewed literature on HRS and interventions in LAC, and synthesize gaps and opportunities for policy, practice, and research. INCLUSION CRITERIA/METHODS:Studies conducted in LAC. The HRS that will be included in the search are opioid agonist therapy, syringe services programs, drug consumption facilities, safer consumption kits, managed alcohol programs, and drug-checking services. The scoping review will consider peer-reviewed original research, including qualitative, quantitative, and mixed-methods designs. We will exclude studies addressing harms associated with nicotine or tobacco use. We included original research written in English, Spanish, Portuguese, or French published between January 2013 and December 2024. METHODS:We will conduct literature searches in English (PubMed, Scopus, Web of Science), Spanish, Portuguese (SciELO and BIREME), and French (BIREME). Two reviewers will independently screen the literature. Extraction of characteristics of the studies using a template in Covidence. Data on the HRS and interventions studied and implemented in LAC will be summarized and presented in tables, graphs, and a narrative summary. We will use a narrative synthesis approach to summarize implications for policy, research, and practice identified in the literature. The review was registered in Open Science Framework (https://osf.io/qya7c/). DISCUSSION/CONCLUSIONS:The proposed scoping review will provide valuable information regarding the current state of HRS and interventions for PWUD in LAC. This in return can help guide future research for evaluating services that are already being implemented or unveil services needed in the region. To our knowledge, this is the first scoping review to map HRS in LAC using a systematic approach. Furthermore, among the strengths of this review are: the broad number of services, countries, and time, as well as the consultation with experts and knowledge users.
PMCID:12643314
PMID: 41284692
ISSN: 1932-6203
CID: 5968022
Education Research: EEG Instruction: Findings from a Scoping Review
Fernandez, Andres; Asoodar, Maryam; Laynor, Gregory; Peedin, Alexis; Ratliff, Jeffrey B; Vaid, Urvashi; Karmarkar, Swati A; Sur, Moushumi; van Kranen-Mastenbroek, Vivianne; Papanagnou, Dimitrios; Majoie, Marian H J M; Balmer, Dorene F; Thammasitboon, Satid
BACKGROUND AND OBJECTIVES/UNASSIGNED:Although EEG interpretation is a key skill in neurology, EEG instruction is variable and its landscape remains underexplored. Thus, we conducted a scoping review to expand the literature by providing a structured mapping of the EEG instruction literature and a foundation for future research in EEG instruction. METHODS/UNASSIGNED:We followed a structured methodological framework for scoping reviews and report the findings in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews. Research questions explored theoretical frameworks, methodologies, learner populations, instructional methods, and assessment approaches. Eligibility criteria were iteratively modified to focus on studies on EEG instruction. A search strategy was developed by a systematic review librarian including the following databases: Scopus, PubMed, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, CENTRAL, and Education Resources Information Center. An initial search was conducted in 2021, with a subsequent updated search to cover studies from 2022 to 2024. Screening was conducted in Covidence using dyads, with discrepancies resolved by a third reviewer. Data extraction categories were developed for the included studies. RESULTS/UNASSIGNED:Thirty-three EEG instruction studies were included in this scoping review. Most studies were published since 2014, were conducted in North America, originated in single institutions, and were published in neurology/neuroscience journals. Almost half of the studies had neurology trainee learner populations, but other specialty trainees were also represented. There was a dearth of theoretical frameworks underpinning the studies, and all studies used quantitative methodologies. Instructional approaches clustered around didactic instruction, online-based instruction, and experiential learning, with several studies using multiple modalities. Assessment approaches clustered around multiple-choice question tests, tests based on EEG samples, and standardized summative tests. Several studies used multiple assessment approaches, but most were lower level (Kirkpatrick level 1 or 2). DISCUSSION/UNASSIGNED:Our scoping review reveals a surge in publications on EEG instruction with a trend toward multimodal instructional approaches, with an assessment focus on knowledge. The findings from this scoping review highlight 3 areas for growth and improvement that future research might address: increase the rigor of research on EEG educational interventions, advance the scope of EEG instruction research, and enhance the precision of EEG instruction.
PMCID:12570072
PMID: 41169758
ISSN: 2771-9979
CID: 5961702
Quality improvement of a community-engaged authorship system: lessons learned from the RECOVER initiative
Esquenazi-Karonika, Shari; Mathews, Patenne D; Wood, Marion J; Mudumbi, Praveen M; Linton, Janelle; Briscoe, Jasmine; Seibert, Elle; Coombs, K; Laynor, Gregory; Katz, Stuart D; Chung, Alicia
BACKGROUND:Inclusion of patients, caregivers, and community members in scientific research should be essential for patient-centered care. Patients’ lived experiences can propose new areas of focus that may not have previously been considered, ensure that potentially sensitive topics are addressed thoughtfully, contribute to the interpretation of findings, and identify future directions of research. Further, their inclusion in the drafting of manuscripts can ensure that research findings are translatable to real-world practice. To achieve this goal, the Researching COVID to Enhance Recovery (RECOVER) consortium developed a Representative Authorship system for development of scientific manuscripts that report RECOVER data. This paper describes a Quality Improvement (QI) project that was conducted to identify system strengths and improvement opportunities. METHODS:An online QI survey was distributed to RECOVER’s Representative Authors about a year into the implementation of the Representative Authorship System. The survey focused on several key aspects, including the clarity regarding the authorship process, training opportunities, the matching process, communication within writing groups, and the perceived impact of the representative engagement on the quality and applicability of research. The survey also explored participants’ satisfaction with compensation, support, and involvement in the system, as well as areas for improvement. RESULTS:The survey was sent to 49 representative authors with 17 respondents (35%). Most respondents reported positive experiences, highlighting the effective matching to manuscripts based on their expertise and the perceived positive impact of their involvement on research outcomes. Additionally, participants felt that including diverse voices enhanced the relevance of research for clinical practice. Several areas for improvement were identified, including communication challenges within writing groups, the utility of manuscript orientation calls, and the fairness of compensation. Respondents also indicated a need for more training opportunities and logistical support. CONCLUSIONS:RECOVER’s Representative Authorship system is effective in fostering collaboration and improving the inclusivity of scientific research. The survey findings indicate that there are logistical changes around communication, training, and compensation that could enhance the experience for all collaborators. Based on these findings, we plan to implement changes to improve awareness, understanding, and collaboration. Additional work is needed to solicit feedback from investigators and administrative staff to obtain a more holistic understanding of the system. SUPPLEMENTARY INFORMATION:The online version contains supplementary material available at 10.1186/s12913-025-12914-3.
PMCID:12225380
PMID: 40611083
ISSN: 1472-6963
CID: 5888422
A Scoping Review on the Development, Implementation, and Evaluation of Nurse Well-Being Initiatives in Academic Health Systems
Withall, Jennifer; Laynor, Gregory; Anglin, Carlita; M Millon, Emma; Bass, Benjamin; Alendy, Fariza; DeMarco, Kathleen; Zavotsky, Kathleen Evanovich
BACKGROUND:Nursing well-being is foundational to the specialties workforce and broader healthcare industry worldwide. Despite frequent reports and descriptions of activities that support nurses' well-being, most reports describe singular activities and programs that lack science-based structures contextualized within academic healthcare systems (AHS) with validated impact. AIMS/OBJECTIVE:To evaluate and synthesize the existing national and international literature on nurse well-being initiatives offered in AHS. METHODS:Over 18 months, an 8-member interprofessional team conducted a scoping review adhering to PRISMA-ScR reporting guidelines. Five databases were searched, and results were screened in a multistep process by researcher pairs. Discrepancies were resolved by a third team member's review. Citations were reviewed uniquely three times to ensure methodological rigor. A final set of 54 articles was extracted for key data elements pertinent to the research question describing setting, population, study design, intervention, and other subsidiary fields. Reviewers additionally analyzed publication quality indicators and trends for additional implications for research and practice. RESULTS:Among the 54 eligible articles, 72% were research and 28% were evidence-based practice, quality improvement, or doctoral dissertations. The concepts studied were psychosocial (e.g., resiliency) and physical (e.g., sleep). The number of instruments used per study ranged from 1 to 11. Thirty percent of studies utilized a framework from various disciplines that included nursing, social and behavioral sciences, and safety science principles. Nurses were included as authors 67% of the time, and 35% received funding from either the public or private sector.
PMID: 40572021
ISSN: 1741-6787
CID: 5874842
From Questions to Answers: Teaching Evidence-Based Medicine Question Formulation and Literature Searching Skills to First-Year Medical Students
Magro, Juliana; Plovnick, Caitlin; Laynor, Gregory; Nicholson, Joey
INTRODUCTION/UNASSIGNED:Medical students may arrive at medical school with some research background but not necessarily evidence-based medicine (EBM) skills. First-year preclinical medical students require foundational skills for EBM (formulating background and foreground questions, navigating information sources, and conducting database searches) before critically appraising evidence and applying it to clinical scenarios. METHODS/UNASSIGNED:We developed a flipped classroom EBM workshop for preclinical students combining prework modules and a 60-minute in-person session. After completing the online modules on foundational EBM skills, students participated in an in-person activity based on patient cases. In small groups, students formulated background and foreground questions based on a case and looked for evidence in resources assigned to each group. Small groups reported back to the whole group how they searched for information for their patient cases. A total of 105 first-year medical students were required to complete this workshop after concluding their basic sciences courses. RESULTS/UNASSIGNED:= .002). DISCUSSION/UNASSIGNED:This flipped classroom approach to teaching foundational EBM skills may be adapted for different contexts, but educators should consider time limitations, group size, and tools for interactivity.
PMCID:11832641
PMID: 39968292
ISSN: 2374-8265
CID: 5841032
Addressing the immigrant screening gap: A protocol for a systematic review on interventions to enhance colorectal cancer screening among immigrants in the United States
McCready, Taylor M; Cohen, Ethan M; Laynor, Gregory; Chebli, Perla; Liang, Peter S; Renson, Audrey
INTRODUCTION/BACKGROUND:Colorectal cancer (CRC) screening rates are lower among immigrant populations in the United States (US) than the general population. Immigrant communities face structural barriers that disincentivize their engagement from CRC screening. A growing body of literature has evaluated the effects of interventions aimed at increasing CRC screening engagement among various immigrant groups, but there has not yet been a systematic synthesis of this literature. OBJECTIVE:This review will systematically evaluate quantitative studies assessing the effects of interventions designed to increase CRC screening rates among immigrant populations residing in the US. METHODS:We will conduct a comprehensive search of English language peer-reviewed and grey literature using specific keywords and database-specific structured vocabulary on interventions to improve CRC screening rates among immigrants published in 7 databases (PubMed, Cochrane Library (Wiley), CINAHL (EBSCO), ClinicalTrials.gov, Embase (Ovid), Scopus (Elsevier), and Web of Science) from January 1, 2000 to December 31, 2024. All studies will be imported into Covidence. Two reviewers will independently screen titles, abstracts, and full-texts for inclusion and exclusion criteria. Pilot screenings and consensus discussions will ensure accuracy and agreement in study selection and data extraction. Iterative data extraction of eligible studies will include critical appraisal using the Risk of Bias 2 (ROB2) for randomized controlled trials, while other study designs will be appraised with the risk of bias in nonrandomized studies of interventions (ROBINS-I) tool. Data synthesis will disaggregate pooled effect estimates by ethnicity, to the extent possible. The study protocol was pre-registered in International Prospective Register of Systematic reviews (PROSPERO): CRD42023488183. EXPECTED OUTPUTS/UNASSIGNED:This systematic review aims to generate an exhaustive summary of the evidence base, including a description of the intervention methods and settings, target populations, recruitment and retention strategies, partnerships and collaborations, and reported outcomes. The results will provide actionable recommendations for public health practitioners, healthcare providers, and policymakers developing tailored interventions and policies aimed at improving CRC screening uptake among diverse immigrant populations in the US.
PMCID:12040244
PMID: 40299980
ISSN: 1932-6203
CID: 5833582
Suicide and Self-Harm Events With GLP-1 Receptor Agonists in Adults With Diabetes or Obesity: A Systematic Review and Meta-Analysis
Ebrahimi, Pouya; Batlle, Juan Carlos; Ayati, Aryan; Maqsood, M Haisum; Long, Clarine; Tarabanis, Constantine; McGowan, Natalie; Liebers, David T; Laynor, Gregory; Hosseini, Kaveh; Heffron, Sean P
IMPORTANCE/UNASSIGNED:Bariatric surgery, once the criterion standard in obesity treatment, has a small but concerning association with increased suicidality. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs), originally developed to treat diabetes, now provide substantial efficacy in the treatment of obesity. However, concerns of risk of suicidality with these medicines have been raised. OBJECTIVE/UNASSIGNED:To evaluate the risk of suicidality and self-harm in randomized, placebo-controlled trials of GLP-1 RAs in adults with diabetes or obesity. DATA SOURCES/UNASSIGNED:MEDLINE, Embase, ClinicalTrials.gov, and Cochrane databases were systematically searched from inception to August 29, 2023. STUDY SELECTION/UNASSIGNED:Reports of randomized clinical trials (RCTs) lasting 6 or more months comparing GLP-1 RAs with placebo for the treatment of diabetes or obesity published in peer-reviewed journals were identified. Two independent reviewers screened all search-identified studies for inclusion. Records of outcomes were queried from primary papers, ClinicalTrials.gov entries, and corresponding authors. DATA EXTRACTION AND SYNTHESIS/UNASSIGNED:Two independent researchers abstracted data and assessed data quality and validity using PRISMA guidelines. Data were pooled using random-effects models. MAIN OUTCOMES AND MEASURES/UNASSIGNED:Pooled incidence of completed or attempted suicide, occurrences of suicidal ideation, or self-harm. RESULTS/UNASSIGNED:A total of 27 of 144 RCTs meeting inclusion criteria systematically recorded suicide and/or self-harm-related events and included 32 357 individuals receiving GLP-1 RAs and 27 046 treated with placebo, over 74 740 and 68 095 person-years of follow-up, respectively. Event incidence was very low in the GLP-1 RA (0.044 per 100 person-years) and placebo (0.040 per 100 person-years) groups, with no statistically significant difference (rate ratio [RR], 0.76; 95% CI, 0.48-1.21; P = .24). Subgroup analyses did not suggest differences in outcomes based on diabetes status or GLP-1 RA used. Five studies were considered at risk of bias due to the loss of more than 5% of participants to follow-up. Otherwise, studies were not found to be heterogeneous nor at high risk of bias. CONCLUSIONS AND RELEVANCE/UNASSIGNED:There is unlikely to be an increase in the very low incidence of suicide-related adverse events among individuals receiving GLP-1 RAs within the context of RCTs. While these findings may further ease concerns about these adverse effects, continued monitoring is warranted to identify particular patients who may be at risk as extended use of GLP-1 RAs expands.
PMCID:11923776
PMID: 40105856
ISSN: 2168-6238
CID: 5813382