Try a new search

Format these results:

Searched for:

in-biosketch:yes

person:petrop04

Total Results:

137


Scanning the aged to minimize missed injury: An EAST multicenter study

Ho, Vanessa P; Kishawi, Sami K; Hill, Hannah; O'Brien, Joseph; Ratnasekera, Asanthi; Seng, Sirivan Suon; Ton, Trieu Hai; Butts, Christopher A; Muller, Alison; Diaz, Bernardo Fabian; Baltazar, Gerard A; Petrone, Patrizio; Pacheco, Tulio Brasileiro Silva; Morrissey, Shawna; Chung, Timothy; Biller, Jessica; Jacobson, Lewis E; Williams, Jamie M; Nebughr, Cole S; Udekwu, Pascal O; Tann, Kimberly; Piehl, Charles; Veatch, Jessica M; Capasso, Thomas J; Kuncir, Eric J; Kodadek, Lisa M; Miller, Samuel M; Altan, Defne; Mentzer, Caleb; Damiano, Nicholas; Burke, Rachel; Earley, Angela; Doris, Stephanie; Villa, Erica; Wilkinson, Michael C; Dixon, Jacob K; Wu, Esther; Moncrief, Melissa L; Palmer, Brandi; Herzing, Karen; Egodage, Tanya; Williams, Jennifer; Haan, James; Lightwine, Kelly; Colling, Kristin P; Harry, Melissa L; Nahmias, Jeffry; Tay-Lasso, Erika; Cuschieri, Joseph; Hinojosa, Christopher J; Claridge, Jeffrey A
BACKGROUND:Despite the high incidence of blunt trauma in older adults, there is a lack of evidence-based guidance for computed tomography (CT) imaging in this population. We aimed to identify an algorithm to guide use of a Pan-Scan (Head/C-spine/Torso) or a Selective Scan (Head/C-spine ± Torso). We hypothesized that a patient's initial history and exam could be used to guide imaging. METHODS:We prospectively studied blunt trauma patients aged 65+ at 18 Level I/II trauma centers. Patients presenting >24 h after injury or who died upon arrival were excluded. We collected history and physical elements and final injury diagnoses. Injury diagnoses were categorized into CT body regions of Head/C-spine or Torso (chest, abdomen/pelvis, and T/L spine). Using machine learning and regression modeling as well as a priori clinical algorithms based, we tested various decision rules against our dataset. Our priority was to identify a simple rule which could be applied at the bedside, maximizing sensitivity (Sens) and negative predictive value (NPV) to minimize missed injuries. RESULTS:We enrolled 5,498 patients with 3,082 injuries. Nearly half (47.1%, n = 2,587) had an injury within the defined CT body regions. No rule to guide a Pan-Scan could be identified with suitable Sens/NPV for clinical use. A clinical algorithm to identify patients for Pan-Scan, using a combination of physical exam findings and specific high-risk criteria, was identified and had a Sens of 0.94 and NPV of 0.86 This rule would have identified injuries in all but 90 patients (1.6%) and would theoretically spare 11.9% (655) of blunt trauma patients a torso CT. CONCLUSIONS:Our findings advocate for Head/Cspine CT in all geriatric patients with the addition of torso CT in the setting of positive clinical findings and high-risk criteria. Prospective validation of this rule could lead to streamlined diagnostic care of this growing trauma population. LEVEL OF EVIDENCE/METHODS:Level 2, Diagnostic Tests or Criteria.
PMID: 38797882
ISSN: 2163-0763
CID: 5663222

Abdominal hernias secondary to non-penetrating trauma. A systematic review

Ceballos Esparragón, José; Dagnesses Fonseca, Javier; Marín García, Jordi; Petrone, Patrizio
Traumatic abdominal wall hernia (TAWH) is a protrusion of contents through a defect in the abdominal wall as a consequence of a blunt injury. The objective of this review was to describe demographic and clinical aspects of this rare pathology, identifying the optimal moment for surgical intervention, evaluating the need to use mesh, and analyzing the effectiveness of surgical treatment. Thus, a systematic review using PubMed, Embase, and Scopus databases was carried out between January 2004 and March 2024. Computed tomography is the gold-standard imaging test for diagnosis. Open surgery is generally the preferred approach, particularly in emergencies. Acute TAWH can be treated by primary suture or mesh repair, depending on local conditions, while late cases usually require mesh.
PMID: 39009304
ISSN: 2173-5077
CID: 5718202

A Quality Improvement Initiative to Implement Focused Family Meetings in the Surgical Intensive Care Unit: Does It Matter?

Maniar, Yesha; Chalasani, Haarika; Messerole, Kenneth; Beck, Lindsay; Stright, Adam; Petrone, Patrizio; Islam, Shahidul; Joseph, D'Andrea K
PMID: 39305278
ISSN: 1555-9823
CID: 5722222

A Quality Improvement Initiative to Implement Focused Family Meetings in the Surgical Intensive Care Unit: Does It Matter?

Maniar, Yesha; Chalasani, Haarika; Messerole, Kenneth; Beck, Lindsay; Stright, Adam; Petrone, Patrizio; Islam, Shahidul; Joseph, D'Andrea K
PMID: 39305278
ISSN: 1555-9823
CID: 5722212

A Quality Improvement Initiative to Implement Focused Family Meetings in the Surgical Intensive Care Unit: Does It Matter?

Maniar, Yesha; Chalasani, Haarika; Messerole, Kenneth; Beck, Lindsay; Stright, Adam; Petrone, Patrizio; Islam, Shahidul; Joseph, D'Andrea K
PMID: 39305278
ISSN: 1555-9823
CID: 5722202

A Quality Improvement Initiative to Implement Focused Family Meetings in the Surgical Intensive Care Unit: Does It Matter?

Maniar, Yesha; Chalasani, Haarika; Messerole, Kenneth; Beck, Lindsay; Stright, Adam; Petrone, Patrizio; Islam, Shahidul; Joseph, D'Andrea K
PMID: 39305278
ISSN: 1555-9823
CID: 5722232

Predictors of Length of Hospital Stay After Reduction of Internal Hernia in Patients With a History of Roux-en-Y Gastric Bypass

Sohail, Amir H; Hurwitz, Joshua C; Silverstein, Jeffrey; Hakmi, Hazim; Sajan, Abin; Ye, Ivan B; Pacheco, Tulio Brasileiro Silva; Zielinski, Gregory R; Gangwani, Manesh Kumar; Petrone, Patrizio; Levine, Jun; Kella, Venkata; Brathwaite, Collin E M; Goparaju, Anirudha
BACKGROUND:Postoperative internal hernias after Roux-en-Y gastric bypass (RYGB) have an incidence of 2%-9% and are a surgical emergency. Evidence on factors associated with length of stay (LOS) after emergent internal hernia reduction in RYGB patients is limited. METHODS:This is a retrospective review of patients who underwent internal hernia reduction after RYGB at our tertiary care center over a 5 year period from 2015 to 2020. Demographics, comorbidities, and intra- and postoperative hospital course were collected. Univariate and multivariate linear regressions were used to investigate factors associated with LOS. RESULTS:< .001) were independent risk factors for increased LOS. CONCLUSION/CONCLUSIONS:The most common location of IH after RYGB is Petersen's defect, followed by jejuno-jejunal mesenteric defect. LOS was significantly associated with male sex, exploratory laparotomy, and resection of small bowel.
PMID: 38227350
ISSN: 1555-9823
CID: 5655492

Surgical Antibiotic Prophylaxis: A Proposal for a Global Evidence-Based Bundle

Sartelli, Massimo; Coccolini, Federico; Labricciosa, Francesco M; Al Omari, AbdelKarim H; Bains, Lovenish; Baraket, Oussama; Catarci, Marco; Cui, Yunfeng; Ferreres, Alberto R; Gkiokas, George; Gomes, Carlos Augusto; Hodonou, Adrien M; Isik, Arda; Litvin, Andrey; Lohsiriwat, Varut; Kotecha, Vihar; Khokha, Vladimir; Kryvoruchko, Igor A; Machain, Gustavo M; O'Connor, Donal B; Olaoye, Iyiade; Al-Omari, Jamal A K; Pasculli, Alessandro; Petrone, Patrizio; Rickard, Jennifer; Sall, Ibrahima; Sawyer, Robert G; Téllez-Almenares, Orlando; Catena, Fausto; Siquini, Walter
In the multimodal strategy context, to implement healthcare-associated infection prevention, bundles are one of the most commonly used methods to adapt guidelines in the local context and transfer best practices into routine clinical care. One of the most important measures to prevent surgical site infections is surgical antibiotic prophylaxis (SAP). This narrative review aims to present a bundle for the correct SAP administration and evaluate the evidence supporting it. Surgical site infection (SSI) prevention guidelines published by the WHO, CDC, NICE, and SHEA/IDSA/APIC/AHA, and the clinical practice guidelines for SAP by ASHP/IDSA/SIS/SHEA, were reviewed. Subsequently, comprehensive searches were also conducted using the PubMed®/MEDLINE and Google Scholar databases, in order to identify further supporting evidence-based documentation. The bundle includes five different measures that may affect proper SAP administration. The measures included may be easily implemented in all hospitals worldwide and are based on minimal drug pharmacokinetics and pharmacodynamics knowledge, which all surgeons should know. Antibiotics for SAP should be prescribed for surgical procedures at high risk for SSIs, such as clean-contaminated and contaminated surgical procedures or for clean surgical procedures where SSIs, even if unlikely, may have devastating consequences, such as in procedures with prosthetic implants. SAP should generally be administered within 60 min before the surgical incision for most antibiotics (including cefazolin). SAP redosing is indicated for surgical procedures exceeding two antibiotic half-lives or for procedures significantly associated with blood loss. In principle, SAP should be discontinued after the surgical procedure. Hospital-based antimicrobial stewardship programmes can optimise the treatment of infections and reduce adverse events associated with antibiotics. In the context of a collaborative and interdisciplinary approach, it is essential to encourage an institutional safety culture in which surgeons are persuaded, rather than compelled, to respect antibiotic prescribing practices. In that context, the proposed bundle contains a set of evidence-based interventions for SAP administration. It is easy to apply, promotes collaboration, and includes measures that can be adequately followed and evaluated in all hospitals worldwide.
PMCID:10812782
PMID: 38275329
ISSN: 2079-6382
CID: 5625362

Morbidity and mortality of emergency surgery in octogenarian patient

Morales-García, Dieter; Rabanal-Llevot, José M; García-Diez, Víctor; Colsa-Gutiérrez, Pablo; Rica, Alejandro Suárez-de la; Maseda-Garrido, Emilio; Lage-Sánchez, José M; Marini, Corrado P; Petrone, Patrizio
OBJECTIVE:To evaluate the health outcomes (postoperative morbidity and mortality) and the functional status at discharge of elderly patients older than 80 years who underwent emergency surgery. METHOD/METHODS:Patients > 80 years of age who underwent emergency surgery during one year at the Marqués de Valdecilla University Hospital, Santander, Spain. Preoperative data (age, sex, type of surgery, comorbidity) and postoperative data (complications) were evaluated, as well as in-hospital mortality, at 30 days and 6 months after surgery. RESULTS:Five-hundred-sixty-eight patients underwent emergency surgery between 2018 and 2019. After the review, 407 patients were included in the study. Average age: 86.9 years. Women 61.7%. Mean hospital stay: 10.4 days. Traumatic interventions 41.3%, vascular surgery 19.7%, general-digestive surgery 25.3%. Medium ASA risk: 2.88. Functional status at discharge: 3.15. Postoperative complications: Clavien-Dindo I 40.8%, II 40.3%, IIIA 3.4%, IIIB 2.5%, IVA 3.9%, IVB 2.0% and V 7.1%. Hospital mortality 7.1%, 30-day mortality 10.3%, mortality at 6 months 24.6%. CONCLUSIONS:Patients > 80 years of age undergoing urgent surgery have high preoperative comorbidity, postoperative complications, and high mortality at 30 days and 6 months after surgery. This mortality is more significant in those ASA IV, nonagenarians and those undergoing high-risk surgery.
PMID: 39079252
ISSN: 2444-054x
CID: 5696362

Bariatric and general surgical procedures in obese patients with a history of venous thromboembolism and concurrent anticoagulation therapy

Howell, Raelina S; Liu, Helen H; Brathwaite, Barbara M; Petrone, Patrizio; Akerman, Meredith; Brathwaite, Collin E M
OBJECTIVE:The objective of this study was to examine the use and outcomes of perioperative anticoagulation (AC) in obese patients with a known history of venous thromboembolism event (VTE). METHOD/METHODS:A retrospective review of a prospective database for patients with a VTE history undergoing bariatric and general surgery at a single center (1/2008-12/2017) was performed. Factors assessed included demographics, surgical details, and outcomes. RESULTS:Sixty-five patients underwent 76 procedures: 46 females (71%); mean age 51 years (range 26-73), mean weight 284 pounds (range 110-558), mean body mass index 45 (range 19-87). Comorbidities include hypertension (60%), gastroesophageal reflux disease (54%), osteoarthritis (49%), obstructive sleep apnea (45%), and diabetes (37%). Operations: 22 general surgeries (29%), 20 sleeve gastrectomies (26%), 12 revisions/conversions (16%), 12 Roux-en-Y gastric bypasses (16%), and 10 gastric bands (13%). Modalities: 67% laparoscopic, 28% robotic, and 5% open. Twenty-two patients (34%) had a pre-operative inferior vena cava filter placed with no complications. The mean length of stay was 4.4 days (range 1-31). Complications: seven 30-day readmissions (9%), one 30-day reoperation (1%), and two 90-day VTEs (3%). Thirty-day readmissions: four for inability to tolerate PO, two for small bowel obstruction, and one for symptomatic anastomotic ulcer. CONCLUSIONS:In our patients, post-operative AC could be started without an increased risk of bleeding in patients with a history of VTE undergoing bariatric surgery.
PMID: 39079249
ISSN: 2444-054x
CID: 5696352