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57


Between Usual and Crisis Phases of a Public Health Emergency: The Mediating Role of Contingency Measures

Alfandre, David; Sharpe, Virginia Ashby; Geppert, Cynthia; Foglia, Mary Beth; Berkowitz, Kenneth; Chanko, Barbara; Schonfeld, Toby
Much of the sustained attention on pandemic preparedness has focused on the ethical justification for plans for the "crisis" phase of a surge when, despite augmentation efforts, the demand for life-saving resources outstrips supply. The ethical frameworks that should guide planning and implementation of the "contingency" phase of a public health emergency are less well described. The contingency phase is when strategies to augment staff, space, and supplies are systematically deployed to forestall critical resource scarcity, reduce disproportionate harm to patients and health care providers, and provide patient care that remains functionally equivalent to conventional practice. We describe an ethical framework to inform planning and implementation for COVID-19 contingency surge responses and apply this framework to 3 use cases. Examining the unique ethical challenges of this mediating phase will facilitate proactive ethics conversations about healthcare operations during the contingency phase and ideally lead to ethically stronger health care practices.
PMID: 33998972
ISSN: 1536-0075
CID: 5387002

"Thanks Doc, But I Prefer to Stay" ̶ Finding Our Way Out of Contentious Hospital Discharge Planning [Comment]

Alfandre, David
PMID: 34152920
ISSN: 1536-0075
CID: 4933922

An Exploratory Study of Goals of Care Conversations Initiated with Seriously Ill Veterans in the Emergency Room

Foglia, Mary Beth; Cohen, Jennifer H; Batten, Adam; Alfandre, David
PMID: 33170071
ISSN: 1557-7740
CID: 4675912

A Step in the Wrong Direction: Florida Lawmakers' Interference with Informed Consent for Pelvic Examinations

Alfandre, David; Geppert, Cynthia; Goedken, Jennifer; Schonfeld, Toby
PMID: 33715923
ISSN: 1878-4321
CID: 4836562

Informed Consent by Any Other Name: Consent Processes for Emergency Use Authorization

Weaver, Meaghann S; Alfandre, David J
PMID: 33645658
ISSN: 1552-4604
CID: 4825832

Ethics Frameworks and Beyond"”Advancing Our Understanding of the Contingency Phase to Improve Health Care Quality During Public Health Emergencies

Alfandre, D.; Sharpe, V.; Geppert, C.; Foglia, M.; Berkowitz, K.; Chanko, B.; Schonfeld, T.
SCOPUS:85111395808
ISSN: 1526-5161
CID: 5000932

Multi-Level Predictors of Discharges Against Medical Advice: Identifying Contributors to Variation Using an All-Payer Database

Onukwugha, Eberechukwu; Nagarajan, Madhu; Offurum, Ada; Gulati, Mangla; Alfandre, David
ABSTRACT/UNASSIGNED:There is increasing evidence of the role of non-patient-level factors on discharge against medical advice (DAMA), but limited quantitative information regarding the extent of their impact. This study quantifies the contribution of discharge-level and hospital-level factors to the variation in DAMA. We grouped variables from the 2014 National Inpatient Sample data and ran incremental mixed-effects logit models with grouping at the level of the discharge, the hospital, and the census region. We obtained the intraclass correlation coefficients (ICCs), and evaluated the incremental change in ICC. The final sample included 2,687,430 discharges. 12.8% of the identified variation in the probability of DAMA was associated with the hospital, and 1.2% of the variation was associated with the census division in which the hospital was located. The final, fully-adjusted model had 7.3% of variation in DAMA associated with the hospital-level, with the greatest percentage reductions because of the addition of patient demographics. Even after adjusting for measured patient-level characteristics, there was a contribution of non-patient-level factors to DAMA outcomes. The findings identify a role for a multi-level approach to addressing DAMA.
PMID: 32134810
ISSN: 1945-1474
CID: 4774092

Healthcare Resource Utilization Following a Discharge Against Medical Advice: An Analysis of Commercially Insured Adults

Gandhi, Aakash Bipin; Onukwugha, Eberechukwu; McRae, Jacquelyn; Alfandre, David
BACKGROUND:A discharge against medical advice (DAMA) is associated with adverse health outcomes. Its association with postdischarge healthcare resource utilization (HcRU) outside an inpatient setting is unknown. This information can help us understand how a DAMA may affect healthcare-seeking behavior following a hospital stay. We evaluated the relationship between a DAMA and 30-day postdischarge HcRU. METHODS:Plus database. We included individuals aged 18 to 64 years with an inpatient admission during 2007-2015 and continuous insurance coverage. We defined comparison groups as DAMA and routine discharge. Both groups were matched on baseline covariates. We quantified the association between a DAMA and 30-day HcRU, as well as 90-day for sensitivity analysis, with use of generalized linear models for binary outcomes (inpatient readmissions, emergency department [ED] visits) and count outcomes (physician office visits, nonphysician outpatient encounters, prescription drug fills). RESULTS:Of the 457,530 individuals in the unmatched sample, 2,245 (0.5%) had a DAMA. In the matched sample, a DAMA was positively associated with an ED visit (adjusted odds ratio, 2.28; 95% confidence interval, 1.90-2.72) but not with an inpatient readmission. There were no differences between groups based on the count outcomes. A DAMA was positively associated with 90-day HcRU (ie, inpatient readmission, ED visit, and prescription drug fills). CONCLUSION/CONCLUSIONS:The relationship between a DAMA and HcRU varied with the HcRU category and postdischarge time interval. This examination of HcRU in the inpatient and outpatient settings provides important information about outcomes following a DAMA.
PMID: 33231545
ISSN: 1553-5606
CID: 4721762

"Doc, I'm Going for a Walk": Liberalizing or Restricting the Movement of Hospitalized Patients-Ethical, Legal, and Clinical Considerations

Alfandre, David; Stream, Sara; Geppert, Cynthia
When patients are admitted to the hospital, they are generally expected to remain in or within close proximity to their assigned rooms in order to promote their safety and appropriate medical care. Although there are circumstances when patients may safely leave their hospital room or floor, guidance within the medical literature for the management of patient movement within the hospital are lacking. Excessive restrictions on patient movement may be seen as overly paternalistic, while lax requirements may interfere with high quality care, patient safety and efficient hospital practice. As a result, guidance in the form of institutional policy is warranted. Such policy development should take into consideration the potential clinical, legal, and ethical concerns in balancing the competing values of patients' preferences and respect for autonomy, while ensuring high quality, safe, and efficacious medical care. This paper will provide a framework for hospitals to create institution-specific patient movement policies that are fair, systematic, and transparent.
PMID: 32240442
ISSN: 1572-8498
CID: 4371542

PNS42 AGAINST MEDICAL ADVICE (AMA) DISCHARGES AND 30-DAY HEALTHCARE COSTS: AN ANALYSIS OF COMMERCIALLY INSURED ADULTS [Meeting Abstract]

Onukwugha, E; Gandhi, A B; Alfandre, D
Objectives: Discharges against medical advice (AMA) occur when patients leave the hospital prior to a physician-recommended endpoint. It is unknown whether AMA discharges are associated with higher healthcare costs within 30 days of discharge. We examine healthcare costs following a hospital discharge in a commercially insured population.
Method(s): This retrospective cohort study examined individuals aged 18 to 64 with a hospitalization during 2007-2015 from a 10% random sample of enrollees in the IQVIATM Adjudicated Health Plan Claims Data. We included individuals with insurance coverage 6 months before and 30 days after their first hospitalization. Individuals with AMA and non-AMA discharges were matched on baseline covariates. Generalized linear models and cost ratios (CR) were used to quantify the association between AMA discharges and 30-day costs. We report CRs overall and by points of service (inpatient, emergency department (ED), physician office, non-physician outpatient encounter (NPOE) and prescription drug fill).
Result(s): Of the 467,746 individuals in the unmatched sample, 2,164 (0.46%) were discharged AMA. Mean (median) costs were 20% (5%) higher in the AMA group compared to the non-AMA group. In the matched sample and relative to those discharged routinely, individuals with an AMA discharge incurred 1.20 times (95% CI: 1.08, 1.34) higher costs. Similarly, individuals with an AMA discharge incurred higher inpatient (CR: 1.71, 95% CI: 1.45, 2.01) and ED (CR: 2.10, 95% CI: 1.84, 2.39) costs within 30 days post-discharge. Conversely, individuals with an AMA discharge incurred lower NPOE (CR: 0.84, 95% CI: 0.74, 0.95) and prescription drug fill (CR: 0.81; 95% CI: 0.73, 0.91) costs. There were no differences in physician office visit costs across the two groups.
Conclusion(s): An AMA discharge is associated with higher 30-day costs compared to those discharged routinely, particularly for acute care services. Future work should determine whether these findings extend to publicly-insured individuals.
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EMBASE:2005868199
ISSN: 1098-3015
CID: 4441512